JPH11114062A - Plunger rod and plunger cap cover for injection syringe body in which radioactive solution is inclosed - Google Patents

Abstract

PROBLEM TO BE SOLVED: To shield the radiation behind an injection syringe body at the time of administration by interposing a radiation shielding part made of a tungsten alloy or tungsten plastic in the front end of a main body part made of plastic, thereby constituting a plunger rod. SOLUTION: The plunger rod 10 is constituted by forming the main body part 11 of the plastic. An end part 13 made of a light metal, such as aluminum, is formed by interposing the radiation shielding part 12 made of the tungsten alloy or tungsten plastic at the front end of the main body part 11. An external screw thread part 14 having the outer peripheral shape of screw threads of an approximately triangular shape which is a noncircular shape freely attachably and detachably screwed to the internal screw thread part of the internal screw thread part of a rubber gasket 44 slidably inserted into the injection syringe body 40 is formed at the end part 13 made of the light metal. A bar-shaped projecting end is formed at the end part of the external screw thread part 14 to prevent the tight contact of the flat parts of the screw thread of the external screw thread part 14 with the inside bottom walls of the internal screw threads of the gasket 44.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a plunger rod and a flange cap cover, and more particularly to a plunger rod and a flange cap cover for safely using an injection syringe body containing a radioactive solution.

[0002]

2. Description of the Related Art Radiopharmaceuticals include, for example, thallium chloride injection used for diagnosis of heart disease, gallium citrate injection used for diagnosis of malignant tumors and inflammatory lesions, and the like.
Technetium MDP injection used for bone scintigraphy and the like. These radioactive injection solutions need to be administered to the patient with as little as possible radiation exposure to the patient at the time of the administration and in a safe and secure manner to the patient.

[0003] Conventionally, as a syringe used for administration of such a radioactive injection solution, in consideration of the convenience and safety of the user, for example, “a radioactive solution syringe and a radioactive solution syringe disclosed in Japanese Patent No. 2623313” are disclosed. The package is used.

[0004] This type of syringe for radioactive solution is provided with an injection syringe made of glass, plastic, or the like, and a radiation shield cylinder having a see-through window made of lead glass for accommodating the injection syringe. The radioactive solution is filled in a sealed state by a gasket inserted into the injection syringe body and a packing member attached to the tip of the injection syringe body. At the time of use, one end of a plastic plunger rod inserted from the rear end of the injection syringe body is attached to the gasket, and a tip of a packing member projecting outward from a front opening of the radiation shield cylinder body. The part has a configuration in which both cutting needles are inserted.

[0005] The radiation shield cylinder is made of a cylinder of lead, tungsten alloy or the like, and this cylinder is formed with an inner diameter slightly larger than the outer diameter of the syringe for injection so that the syringe for injection can be easily inserted and removed. In addition, a lead glass see-through window for visually confirming the remaining amount of the radioactive solution in the injection syringe and the state of securing blood vessels is formed in a part of the cylindrical body on the side peripheral wall. Further, a flange cap for holding the rear end of the injection syringe body to the radiation shield cylinder is detachably attached to a rear end of the radiation shield cylinder body in a state where the injection syringe body is inserted into the radiation shield cylinder body. I have.

[0006] However, in the injection syringe body of the above-mentioned syringe for radioactive solution, although the radiation shield in the radial direction of the injection syringe body is secured by the radiation shield cylinder, the injection direction of the plunger rod in the axial direction is ensured. However, there was a problem that radiation could not be shielded.
For this reason, a plunger rod made entirely of metal having excellent radiation shielding properties has been put to practical use, but has a drawback that it lacks operability due to its weight.

[0007] In addition, in order to facilitate separation and disposal after use, a detachable screwing means is generally employed for attaching a plunger rod to a gasket of a conventional injection syringe body. In addition to the fact that the gasket is made of a gasket, it often happens that the gasket comes into close contact with the plunger rod and becomes difficult to come off when the time until the removal has elapsed.

Furthermore, depending on the diagnostic method, it may be necessary to inject the radioactive solution in the injection syringe in two stages, but conventionally, it is complicated to administer the appropriate amount by observing the scale. An operation was being performed.

[0009]

SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a flange cap cover which can shield radiation behind an injection syringe body at the time of administration and a plunger rod which is lightweight and excellent in operability. With the goal.

Another object of the present invention is to provide a plunger rod which does not come into close contact with a gasket after mounting and can be easily removed even after a long time has passed.

Still another object of the present invention is to provide a plunger rod capable of dispensing and dispensing an appropriate amount extremely easily and surely without the need for a user to check the scale or the like.

[0012]

In order to achieve the above-mentioned object, the present invention provides a method for manufacturing a main body made of plastic,
A plunger rod is formed by forming a light metal, plastic or tungsten plastic tip by interposing a tungsten alloy or tungsten plastic radiation shielding portion at the front end of the main body. Here, as the light metal, for example, aluminum or the like is preferable, and as the plastic, for example, polyacetal, polyethylene, polypropylene, polyvinyl chloride, polycarbonate, polystyrene, ethylene vinyl alcohol, PET, or the like is used.

[0013] According to such a configuration, the radiation shielding portion can effectively shield radiation behind the injection syringe body during administration, and is mostly composed of plastic and light metal. Light weight and excellent operability.

The present invention also provides a male screw portion having a non-circular screw thread outer peripheral shape which is detachably screwed with a female screw portion of a gasket slidably inserted into an injection syringe body. To form a plunger rod. Here, as the non-circular screw thread outer peripheral shape, for example, a triangular shape, a square shape, and a pentagonal shape are preferable, and these are more preferably provided with a non-sharp roundness by cutting off the corners. preferable.

According to such a configuration, the screw connection can be maintained despite the small contact area between the male screw portion of the plunger rod and the female screw portion of the gasket, so that there is no hindrance to the administration operation. Also, both are prevented from sticking to each other, and can be easily removed even after a long period of time.

Furthermore, in the present invention, if a bar-shaped protruding end is formed at the tip of the male screw portion, the screw thread flat portion of the male screw portion is prevented from closely contacting the inner bottom wall of the female screw portion of the gasket. Therefore, removal of the plunger rod from the gasket can be performed more easily.

Further, in the present invention, a plunger rod is formed by providing a stopper mechanism for adjusting an insertion stroke into an injection syringe body on an outer peripheral portion. Here, as the stopper mechanism, a slidable or detachable flange-shaped ring body locked at the rear end portion of the injection syringe body is preferably exemplified.

According to this configuration, the stroke of inserting the plunger rod into the injection syringe body, that is, the dose of the radioactive solution in the injection syringe body can be adjusted, so that the appropriate amount can be administered very easily and reliably. Can be.

Further, in the present invention, the plunger rod and the plunger rod are removably covered with a flange cap for holding the rear end of the injection syringe body to the radiation shield cylinder, and the plunger rod is provided at the center. The use of a flange cap cover made of tungsten plastic having a plunger rod insertion hole has a particularly good effect on the radiation shielding effect behind the injection syringe body. Here, it is preferable that the flange cap cover has a shape corresponding to the outer shape of the flange cap and can be detachably fitted.

[0020]

Embodiments of the present invention will be described below with reference to the drawings.

FIG. 1 is an exploded perspective view showing the entire structure of a syringe for a radioactive solution including the plunger rod of the present invention.
2 and 3 are perspective explanatory views showing an embodiment of the plunger rod of the present invention. The syringe for a radioactive solution will be described below with reference to the drawings. 20, flange cap 30, injection syringe body 40, fixing / buffering device 50
And a radiation shield cylinder 60.

The injection syringe body 40 is formed from a transparent cylindrical body having a predetermined diameter such as glass or plastic, and has a cylindrical needle having a diameter sufficiently smaller than the diameter of the injection syringe body 40 at the tip thereof. The attachment part 41 is formed coaxially, and a holding flange part 42 extending in the radial direction is formed at the rear end. In addition, a needle attachment part 41 is formed at the tip of the injection syringe body 40, and a packing member 43 for sealing the radioactive solution is mounted. A gasket 44 is slidable in the injection syringe body 40 in the longitudinal direction of the injection syringe body 40. Has been inserted. One end of the plunger rod 10 inserted from the rear end opening of the injection syringe body 40 is detachably attached to the gasket 44 by screwing means. The injection syringe body 40 defined by the gasket 44 and the packing member 43 is filled with a radioactive solution in a sealed state.

The radiation shield cylinder 60 houses the injection syringe body 40 filled with a radioactive solution, and is formed from a cylinder of lead, tungsten alloy or the like having both ends opened. The inner diameter of the radiation shield cylinder 60 is formed slightly larger than the outer diameter of the injection syringe body 40 so that the injection syringe body 40 can be easily inserted and removed, and the side wall of the injection syringe body 40 has An elongated transparent window 61 made of lead glass for visually confirming the remaining amount of the radioactive solution and the state of securing blood vessels is formed along the axial direction from the vicinity of the front end of the radiation shield cylinder 60 to the rear.
It should be noted that a double cutting needle (not shown) is inserted into the front end of the packing member 43 that protrudes outward from the front opening of the radiation shield cylinder 60. In addition, a synthetic resin flange tubular portion 62 is fitted around the rear end of the radiation shield tubular body 60. A pair of finger stoppers 62a, on which a finger is hooked at the time of an injection operation, are formed on the side wall of the flange cylindrical portion 62 so as to protrude radially at an interval of 180 degrees in the circumferential direction. A notch 62b with which the retaining flange 42 engages when the injection syringe body 40 is inserted into the radiation shield cylinder 60 is formed on an end face on the rear end side of the flange 60. A locking portion 62c for locking the flange cap 30 is provided on the side wall.
Are protruded.

The flange cap 30 is for holding the rear end of the injection syringe 40 inserted into the radiation shield cylinder 60 to the radiation shield cylinder 60, and has a plunger at the center of the top plate. A hole 31 through which the rod 10 is inserted is formed.
A locking piece 32 that locks with both protrusions 62c of the flanged cylindrical portion 62 is formed on the side wall of the flange cylindrical portion 62.

The flange cap cover 20 is made of tungsten plastic, and is removably fitted to the flange cap 30. The flange cap cover 20 has a plunger rod insertion hole 21 formed in the center similarly to the flange cap 30. In addition, it has a shape and a size suitable for covering the outer surface of the flange cap 30, and as is apparent from the test examples described later, in conjunction with the plunger rod 10, the injection syringe body 40 can be more effectively used. Shield the radiation behind.

The fixing / buffering device 50 supports the insertion destination of the injection syringe body 40 inserted into the radiation shield cylinder 60, and the insertion destination of the injection syringe body 40 and the radiation facing the front end. The distal end of the injection syringe body 40 is interposed between the inner circumferential surfaces of the front end portions of the shield cylinder body 60 and is compressed and deformed in the insertion direction by the pressing force in the insertion direction of the injection syringe body 40 and radially deformed. It is configured to be able to support the shield cylinder 60.

The plunger rod 10 has a main body 11 made of plastic and a radiation shield 12 made of tungsten alloy or tungsten plastic at the front end of the main body 11 to form a light metal tip 13 made of aluminum or the like. It is configured.

The light metal tip 13 has an injection syringe 4
A male screw part 14 having a non-circular, substantially triangular screw thread 15 outer peripheral shape is detachably screwed to a female screw part of a rubber gasket 44 slidably inserted into the inside.

FIG. 2 shows the tip of the male screw portion 14.
As shown in FIG. 5, a bar-shaped protruding end 16 is formed to prevent the flat portion of the screw thread 15 of the male screw portion 14 from being in close contact with the inner bottom wall of the female screw portion of the gasket 44.

Further, in the embodiment shown in FIG. 3, the plunger rod 1 to the injection syringe body 40 is attached to the outer periphery of the plastic body 11 of the plunger rod 10.
A stopper mechanism for adjusting the zero insertion stroke is provided. That is, a short locking groove 18a is formed in the outer wall portion of the plunger rod main body 11 at the position where the insertion stroke is aimed at in the circumferential direction, and is orthogonal to the locking groove 18a. An elongated syringe groove 18b extending in an L-shape is formed in the axial direction toward the rear end, has an engaging groove 18a and a guide projection 17a that protrudes into the slide groove 18b, and has an injection syringe body. A flange-like ring body 17 that is locked with the holding flange 42 of the holding member 40 is locked on the outer periphery of the plunger rod body 11 with the locking groove 18a via the guide projection 17a and the slide groove 18 is provided.
It is slidably mounted along section b.

When the injection syringe 40 is set in the radiation shield cylinder 60 in the syringe for radioactive solution configured as described above, first, the fixing / buffer 50 is attached to the tip of the injection syringe 40. Packing member 43
The notch 53 of the injection syringe body 40 is inserted into the radiation shield cylinder 60 from the rear end opening of the radiation shield cylinder 60 from the packing member 43 side so as to coincide with the lead glass see-through window 61 from the packing member 43 side. When adjusted and inserted, the front end side of the lead glass see-through window 61 is not obstructed by the fixing / buffer 50 in view.

Next, after the retaining flange 42 of the injection syringe body 40 is engaged with the notch 62b of the flange cylindrical portion 62,
Covering the flange cap 30 with the flange cylinder portion 62,
The locking piece 32 is resiliently locked to the locking portion 62c of the flange cylinder portion 62. Thereby, the flange cap 30
Is mounted on the rear end of the radiation shield cylinder 60, and fixes and holds the rear end of the injection syringe body 40 to the radiation shield cylinder 60.

Next, the flange cap cover 20 is resiliently fitted to the outer surface of the flange cap 30 and covered. Next, when injecting the radioactive solution filled in the injection syringe body 40 into a patient or the like, the holes 21 of the flange cap cover 20 and the holes 31 of the flange cap 30 are used.
The male screw portion 14 of the plunger rod 10 inserted through is inserted and screwed into a gasket 44 in the injection syringe body 40, and one of the double cutting needles (not shown) is inserted into the packing member 43, and the other of the double cutting needles is inserted. If the plunger rod 10 is moved forward while piercing the patient's blood vessel, the radioactive solution in the syringe body for injection 40 can be injected.

In this case, in the embodiment shown in FIG.
If the flange-shaped ring body 17 is locked and fixed by the locking groove 18a, the plunger rod 10 stops at a target position during the entire insertion stroke, so that the dose can be adjusted. When the remaining amount is to be administered, the collar-shaped ring body 17 is slightly rotated to disengage it from the locking groove 18a,
After moving to the rear end along the slide groove 18b,
What is necessary is just to move the plunger rod 10 further forward.

Next, the present invention will be further described with reference to test examples. Test example Techne MDP (methylene diphosphonic acid) injection (SD)
As shown in FIG. 1, the injection syringe body containing 1.056 GBq was housed in a radiation shield cylinder body, and after covering a flange cap, each of the following plunger rods was attached to a gasket, and 45 mm above the flange cap. (The site where the thumb is located at the time of administration)
Radiation shielding effect in ionization chamber survey meter (Aloka)
Model ICS-315Ser. Measured with 96R162. The results are shown in Table 1.

Control product: Injection syringe with no plunger rod attached Conventional product: Plunger rod entirely made of plastic Invention product 1-1: Tungsten radiation shielding part having a thickness of 2 mm and a diameter of 8.8 mm The plunger rod shown in FIG. 2 having the present invention 1-2: the plunger rod shown in FIG. 2 having a tungsten radiation shielding part having a thickness of 3 mm and a diameter of 8.8 mm The present invention 1-3: the thickness of 7 mm, diameter Plunger rod shown in FIG. 2 having a 8.8 mm tungsten radiation shielding part. Invention product 1-4: Plunger rod shown in FIG. 2 having a tungsten radiation shielding part having a thickness of 3 mm and a diameter of 9.0 mm. Article 2-1: The present invention 1-1 further using the flange cap cover shown in FIG. 1 together. The present invention 2-2: The present invention 1-2 further comprises a flange shown in FIG. Inventive product 2-3: Inventive product 1-3: In addition to inventive flange 1-3 in addition to the flange cap cover shown in FIG. 1. Inventive product 2-4: Inventive product 1-4, further shown in FIG. With flange cap cover

[0037]

[Table 1]

[0038]

According to the present invention, the use of the plunger rod and the flange cap cover makes it possible to shield the radiation behind the injection syringe body at the time of administration, and the operability is markedly lower than before because of its light weight. Excellent. Also,
If the plunger rod of the present invention is used, the adhesion after the attachment with the gasket is prevented, so that the detachment after use is easy and the sorting and disposal can be performed smoothly. Furthermore, if the plunger rod of the present invention is used, the user can dispense an appropriate amount very easily and surely without looking at the scale or the like.

[Brief description of the drawings]

FIG. 1 is an exploded perspective view showing the entire configuration of a syringe for radioactive solution including a plunger rod and a flange cap cover of the present invention.

FIG. 2 is a perspective explanatory view showing an embodiment of the plunger rod of the present invention.

FIG. 3 is a perspective explanatory view showing another embodiment of the plunger rod of the present invention.

[Explanation of symbols]

 10: Plunger rod 11: Body part 12: Radiation shielding part 13: Tip part 14: Male screw part 15: Screw thread 16: Rod-shaped protruding end 20: Flange cap cover 21: Hole 30: Flange cap 31: Hole 40: Injection Syringe body 44: Gasket 50: Fixing / buffer 60: Radiation shield cylinder

Claims (11)

[Claims] 1. A body made of plastic,
A plunger rod for an injection syringe body, in which a radioactive solution is sealed, wherein a tip made of light metal, plastic or tungsten plastic is formed by interposing a radiation shielding part made of tungsten alloy or tungsten plastic at the front end of the main body. 2. A male screw part having a non-circular screw thread outer peripheral shape in which a light metal tip part is removably screwed with a female screw part of a gasket slidably fitted in an injection syringe body. The plunger rod according to claim 1, wherein the plunger rod is provided. 3. The plunger rod according to claim 2, wherein the male screw portion has a rod-shaped protruding end at its tip. 4. The plunger according to claim 1, wherein the plastic main body has a stopper mechanism for adjusting an insertion stroke of the plastic main body at an outer peripheral portion thereof. rod. 5. The plunger rod according to claim 4, wherein the stopper mechanism is a slidable or detachable flange-shaped ring body which is engaged with a rear end portion of the injection syringe body. 6. A flange cap made of tungsten plastic, which is detachably covered by a flange cap for holding a rear end of an injection syringe body to a radiation shield cylindrical body and has a plunger rod insertion hole at a central portion. The plunger rod according to any one of claims 1 to 5, further comprising a cover separately. 7. A male screw portion having a non-circular screw thread outer peripheral shape removably screwed with a female screw portion of a gasket slidably inserted into an injection syringe body, is formed at a front portion. A plunger rod for an injection syringe in which a radioactive solution is enclosed. 8. The plunger rod according to claim 7, wherein the male screw portion has a rod-shaped protruding end at its tip. 9. A plunger rod for an injection syringe containing a radioactive solution, wherein a stopper mechanism for adjusting an insertion stroke into the injection syringe is provided on an outer peripheral portion. 10. The plunger rod according to claim 9, wherein the stopper mechanism is a slidable or detachable flange-shaped ring body locked at a rear end portion of the injection syringe body. 11. A tungsten plastic flange which is detachably covered with a flange cap for holding a rear end of a syringe body for injection to a radiation shield cylindrical body and has a plunger rod insertion hole at a central portion. Cap cover.