JP2008134268A - Radioactive solution syringe assembly - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To facilitate decomposition for reuse in a radioactive solution injection syringe sealing a radioactive solution. <P>SOLUTION: This radioactive solution syringe assembly 4 is provided with a syringe 5 holding the radioactive solution, a radiation shielding cylinder 6 storing the syringe 5, and a finger plate cylinder 7 attached to a base end of the shielding cylinder 6 and provided with a finger fitting piece 71 used in an injection. The finger plate cylinder 7 is provided with an inward flange 73 in a base end thereof, and a flange 52 of the syringe 5 is sandwiched by the inward flange 73 and the base end of the shielding cylinder 6. A heat shrinkable film tube 8 is tightly put under a shrunk condition thereof, ranging over the shielding cylinder 6 and the finger plate cylinder 7. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a packaging protective case for containing a radioactive substance and a radioactive solution syringe assembly contained in the case.

  For example, it is well known to use radioactive solutions such as thallium chloride injection for the diagnosis of heart disease. In order to use such a radioactive solution for safe and reliable transportation, the radioactive solution syringe assembly 4 shown in FIG. 5 and a packaging protective case 1 for housing the syringe assembly are publicly known and have already been proposed (see Japanese Patent No. 2623313). ).

  The radioactive solution syringe assembly 4 includes a syringe 5 enclosing a radioactive solution, a radiation shield cylinder 6 containing the syringe 5, and a finger hook piece 71 at the time of injection, and is attached to the proximal end of the shield cylinder 6. And a finger-holding cylinder 7. The finger hook cylinder 7 means a sleeve that can be engaged with a finger.

The packaging protective case 1 includes a case body 2 and a lid body 3 mainly composed of lead. A foamed resin cushioning material 28 is fitted into the case body 2, and a recess 29 corresponding to the shape of the radiation solution syringe assembly 4 is formed in the foamed resin cushioning material 28.
The packaging protective case 1 accommodates the radioactive solution syringe assembly 4 in the recess 29 of the foamed resin cushioning material 28 to prevent leakage of radiation to the outside as much as possible.

  The shield cylinder 6 has a proximal end that fits into the finger hook cylinder 7 and is fitted into the syringe 5 to prepare the radioactive solution syringe assembly 4. A flange cap 9 is provided on the inner surface of the lid 3 of the packaging protection case 1. The flange cap 9 is placed on the finger tube 7 from the base end side of the shield tube 6, and the leg claw 91 of the flange cap 9 is engaged with the step portion 75 of the finger tube 7 to hold the finger tube 7. Yes.

  The radioactive solution syringe assembly 4 can be taken out of the packaging protective case 1 while the syringe 5 is fitted to the shield cylinder 6, and the subject can be injected with the radioactive solution in that state. Thereby, radiation exposure to an administrator (medical doctor etc.) can be prevented.

Japanese Patent No. 2623313

However, this proposed means has the following problems. Lead is often used as a radiation protection material, but lead has the problem of poisoning or contamination. In the above conventional packaging protective case, the upper inner surface of the case body 2 is not covered with the foamed resin cushioning material 28, and the lead forming the inner layer 26 of the case body 2 and the lead plate 36 on the inner surface of the lid 3 are exposed. As a result, the problem of poisoning or contamination remained.
Since the shield cylinder 6 is expensive, it is reused, and a clearance is provided between the syringe 5 and the shield cylinder 6 so that the two elements can be easily separated.

The shield tube 6 has only a base end portion fitted to the finger hook tube 7. Accordingly, when the radioactive solution syringe assembly 4 is taken out from the packaging protective case 1 and the friction resistance between the shield tube 6 and the buffer material 28 is larger than the fitting force between the finger tube 7 and the shield tube 6, the shield tube 6 May remain in the packaging protective case 1.
When the syringe 5 comes out of the shield tube 6, the role of the radiation protection of the shield tube 6 is lost.

  In order to remove the syringe 5 from the shield tube 6 in order to reuse the used shield tube 6 after injecting the radioactive solution into the subject, the flange cap 9 must be removed. Since the flange cap 9 has a plurality of leg claws 91 engaged with the stepped portion 75 of the finger hook cylinder 7, this engagement must be released at the same time and the flange cap 9 must be removed from the finger hook cylinder 7. This work takes time.

Since the shield cylinder 6 needs to be subjected to rust prevention treatment such as silver plating or rust prevention treatment on the surface so as to withstand reuse, the cost increases.
In the packaging protective case 1, since the outer layer 27 is a resin, its strength is small, and there is a possibility that the outer layer 27 may be damaged during transportation.

  An object of the present invention is to provide a radioactive solution syringe assembly that can solve the above problems.

  According to the present invention, the syringe 5 enclosing the radioactive solution is accommodated in the radiation shield cylinder 6, and the radioactive solution syringe in which the finger hook cylinder 7 having the finger hook piece 71 at the time of injection is attached to the proximal end of the shield cylinder 6. An assembly 4 is provided. The finger hook cylinder 7 has an inward flange 73 at the base end, and a flange 52 protruding from the base end of the syringe 5 is sandwiched between the inward flange 73 and the base end of the shield cylinder 6. A heat-shrinkable film tube 8 is tightly covered in a contracted state across the shield tube 6 and the finger-hanging tube 7.

  FIG. 1 shows a state in which the radioactive solution syringe assembly 4 is accommodated in the packaging protective case 1. A radioactive solution syringe assembly 4 includes a syringe 5 filled with a radioactive solution such as a thallium chloride injection solution or a gallium citrate injection solution, a shield tube 6 fitted outside the syringe 5 to protect radiation, and an injection. It comprises a finger-hanging tube 7 that includes a finger-hook piece 71 and is fitted to the base end of the shield tube 6, and a heat-shrinkable film tube 8 that is mounted across the finger-hanging tube 7 and the shield tube 6.

  The syringe 5 is a transparent cylinder formed of glass or synthetic resin, and has a narrow mouth spout 51 protruding from the tip. The spout 51 is attached to a plastic chip 55, and a rubber cap 56 is attached to the plastic chip 55.

  The proximal end of the syringe 5 has a flange 52 that protrudes short outward. The radioactive solution filled in the syringe 5 is sealed by a packing 54 that closes the spout 51 of the syringe 5 and a piston 53 fitted to the proximal end side of the syringe 5. The piston 53 is provided with a screw hole 53a for attaching the plunger 58.

  The shield cylinder 6 is formed in a cylindrical body capable of fitting the syringe 5 without resistance with a metal having a high density such as tungsten or a tungsten alloy, and is bent conically toward the spout 51 of the syringe 5 at the tip. An inward piece 62 is provided.

The shield tube 6 is provided with a long hole-like window portion 63 from the shoulder portion 57 on the front end side to the rear end side, and a lead glass 64 is fitted into the window portion 63.
The thickness of the lead glass 64 is larger than the thickness of the shield tube 6, and the lead glass 64 protrudes outward from the outer surface of the shield tube 6.

  Referring to FIG. 1, the inwardly facing piece 62 of the shield tube 6 has a slight margin with respect to the distal end side shoulder 57 of the syringe 5 when the base end of the shield tube 6 is in contact with the lower surface of the flange 52 of the syringe 5. It is formed at a position where

  The finger tube 7 is formed of a synthetic resin such as polypropylene, polyethylene, ABS resin, and can be detachably fitted to the base end of the shield tube 6 so that there is no backlash. The finger-hanging cylinder 7 has an inward flange 73 that extends from the base end of the cylinder portion to a length substantially equal to the inner diameter of the syringe 5 base end and covers the flange 52 of the syringe 5. The finger hook cylinder 7 further has a ridge 72 formed on the outer periphery of the tip over the entire circumference. A finger hook piece 71 protruding in a hook shape from the finger hook cylinder 7 is arranged between the inward flange 73 and the protrusion 72 and serves as a finger hook when injecting the radioactive solution in the syringe 5.

  The finger hook cylinder 7 is fitted to the proximal end of the shield cylinder 6, and the inward flange 73 covers the flange 52 of the syringe 5. More specifically, the axial movement of the syringe 5 with respect to the shield tube 6 is restricted by the proximal end of the shield tube 6 and the inward flange 73 of the finger hook tube 7.

  The heat-shrinkable film tube 8 is a tube formed of vinyl chloride, polypropylene, polyethylene terephthalate or the like, which is transparent or partially or almost entirely colored. The diameter of the heat-shrinkable film tube 8 before shrinkage is such that the shield tube 6, the protruding portion of the lead glass 64 fitted to the shield tube 6, and the protrusion 72 of the finger-hanging tube 7 can be fitted in a generous state. It has become. When contracted, the heat-shrinkable film tube 8 has a length that covers the length from the tip-inward facing piece 62 of the shield tube 6 to the lower end of the finger-hanging piece 71 of the finger-hanging tube 7.

  As shown in FIG. 3, the heat-shrinkable film tube 8 is provided with two intermittent cuts 81 and 81 that extend close to each other over the entire length in the axial direction.

  The heat-shrinkable film tube 8 is fitted over the finger tube 7 and the shield tube 6 and heated to shrink the heat-shrinkable film tube 8 mainly in the circumferential direction. Adhere closely. Thereby, the shield cylinder 6 and the finger hook cylinder 7 are integrally held on the syringe 5.

  The packaging protection case 1 includes a case main body 2 having a deep bottom upper surface opening and a lid 3 covering the opening. The packaging protective case 1 has a space 11 in which the radioactive solution syringe assembly 4 can be accommodated.

  The case main body 2 and the lid 3 are both formed by wrapping the radiation shield layers 22 and 32 with metal outer shells 21 and 31, and are not used up after being used once but are reused.

  The outer shell 21 of the case body 2 is formed in a bottomed cylindrical body. The radiation shield layer 22 of the case body 2 is formed in a bottomed cylindrical body like the outer shell 21, and can be fitted in close contact with the inner surface of the outer shell 21. The radiation shield layer 22 has an upper end slightly protruding from the upper end of the outer shell 21. A label (not shown) on which information on the radioactive solution of the radioactive solution syringe assembly 4 is printed is attached to the outer surface of the case body 2.

  The outer shell 31 of the lid 3 is integrally formed on a disc-shaped cover plate 31a, a peripheral wall 31b extending downward from the outer periphery of the cover plate 31a, and a lower portion of the peripheral wall 31b, and an upper end of the outer shell 21 of the case body 2 The fitting short cylinder part 31c which expanded the diameter so that it may fit in a part outer periphery is comprised.

The radiation shield layer 32 of the lid 3 is formed in a thick plate shape that fits in close contact with the inner surfaces of the covering plate 31 a and the peripheral wall 31 b of the outer shell 31.
The outer shells 21 and 31 of the case main body 2 and the lid 3 are made of a metal such as iron, stainless steel, copper alloy such as brass, tungsten or tungsten alloy, and the types thereof are not limited.

However, the outer shells 21 and 31 of the present invention can provide the radiation protection effect, and the radiation protection effect is related to the density of the substance used for the outer shells 21 and 31. Therefore, if the outer shells 21 and 31 are formed of tungsten or a tungsten alloy having a density higher than that of other metals, the thickness of the outer shells 21 and 31 can be reduced when the same radiation protection effect is obtained.
For those that do not require radiation protection, the thickness of the outer shell can be 0.5 mm or less.

  The radiation shield layers 22 and 32 of the case body 2 and the lid body 3 are made by kneading metal powder or metal particles into molten resin, can be fitted into the outer shells 21 and 31, and contain the radioactive solution syringe assembly 4. It is formed into a shape that defines a possible space 11.

  As described above, the material of the metal powder or metal particles used for the radiation shield layers 22 and 32 is preferably a metal having a high density such as tungsten, a tungsten alloy, or lead in terms of the effect of radiation protection. Furthermore, in order to prevent the metal powder or metal particles from being exposed on the surfaces of the radiation shield layers 22 and 32, a shape close to a spherical shape is desirable. Furthermore, the metal powder or metal particles should be at least one type.

  According to the present invention, metal powder means a powder having a particle size of less than 1 mm, and metal particle means a particle or pellet having a particle size or particle size of at least 1 mm to 5 mm. Even in the case of metal powder, it is desirable that the particle size be at least 0.5 mm in consideration of prevention of scattering of the metal powder before the kneading operation with the resin.

  In order for the radiation shield layers 22 and 32 to obtain a high radiation protection effect, it is necessary to mix a large amount of metal powder or metal particles. The amount of metal powder or metal particles mixed in the resin may be in the range of 50 to 80% in volume ratio.

  In order to homogenize the radiation shield layers 22 and 32, it is necessary to uniformly disperse high density metal powder and metal particles in the molten resin during injection molding. For this purpose, a resin having high viscosity such as polyamide or ABS resin may be used, or a resin that can be molded under high viscosity conditions such as polyethylene or polypropylene may be used.

  When metal powder or metal particles are kneaded with molten resin and molded, the metal powder and metal particles are not directly exposed on the surface of the molded product. Therefore, even if the radiation shield layers 22 and 32 are filled with small lead particles, the handler of the case 1 does not come into contact with lead, so that the problem of lead poisoning does not occur.

  Needless to say, the radiation shield layer 22 of the case body 2 can be integrally formed. If the radiation protection force of the lead glass 64 part of the radioactive solution syringe assembly 4 is weak, however, the corresponding part of the radiation shield layer 22 with the lead glass 64 is a shielding part 24 formed of a material having a high radiation protection effect, The shielding portion 24 can be fitted into the notch portion 23 formed in the radiation shield layer 22.

  On the inner bottom of the radiation shield layer 22 of the case main body 2, a water absorbing member 25 formed of a material having a water absorbing and buffering action such as absorbent paper is disposed, and the radioactive solution is disposed at the center of the water absorbing member. A recess 25a into which the rubber cap 56 of the syringe assembly 4 is fitted is formed.

(When assembled)
When the radioactive solution syringe assembly 4 is stored in the packaging protective case 1, the radioactive solution syringe assembly 4 is stored in the case body 2 with the rubber cap 56 facing down, and the rubber cap 56 is inserted into the recess 25 a of the water absorbing member 25. The cover body 3 is put on the case body 2 in a state where the cover body 3 is fitted.
The radioactive solution syringe assembly 4 is restrained from moving by the radiation shield layers 22 and 32 and the water absorbing member 25 of the packaging protective case 1.

A heat-shrinkable film tube 82 is fitted over the case main body 2 and the lid 3 and is heat-shrinked and sealed.
Like the heat-shrinkable film tube 8 of the radioactive solution syringe assembly 4, the heat-shrinkable film tube 82 has two intermittent cuts for opening that extend close to and parallel to the axial direction of the tube. Is provided.

  The heat-shrinkable film tube 82 can be printed with all or part of information such as the product name and content regarding the radioactive solution of the radioactive solution syringe assembly 4. Furthermore, some of the information of the radioactive solution can be represented by the color of the tube 82 of the film.

  Unlike the conventional resin outer packaging protection case, the case body 2 and the lid 3 of the packaging protection case 1 are made of metal, so that they are resistant to impacts and are damaged during transportation and storage. It is possible to prevent radiation leakage due to accidents and fires. Since the radiation shield layers 22 and 32 surrounded by the outer shells 21 and 31 are formed of a resin mixed with metal powder or metal particles, they have a buffer function as well as a role of radiation protection. Therefore, it is not necessary to use a foamed resin cushioning material for the inner layer as in the prior art, and the contained radioactive solution syringe assembly 4 is effectively protected from impact during transportation.

  The heat shrinkable film tube 82 that seals the lid 3 is printed with all or part of information such as the product name and content of the radioactive solution of the radioactive solution syringe assembly 4, or the color of the film tube 82 is Used to represent some of this information. Even when the information label affixed to the case body 2 is not correctly arranged in a visible direction, the user can check information on the radioactive solution from the film tube 82.

(how to use)
When the radioactive solution syringe assembly 4 is used, the heat shrinkable film tube 82 is broken to remove the lid 3 and the radioactive solution syringe assembly 4 is taken out. By tearing the heat-shrinkable film tube 82, it is displayed whether it has been opened, that is, whether the radioactive solution syringe assembly 4 has been used.

Since the film tube 8 that has been heat-shrinked over the finger-clamping cylinder 7 and the shield cylinder 6 is covered and the finger-clamping cylinder 7 and the shield cylinder 6 are held in a fixed state, the two elements are not inadvertently separated. .
Since the film tube 8 gives an aesthetic appearance to the surface of the shield tube 6 and acts as a protective film, it is not necessary to apply silver plating or rust prevention treatment to the surface of the shield tube 6. Therefore, the packaging protective case 1 can be manufactured at a relatively low cost.

  Furthermore, since the heat-shrinkable film tube 8 also covers the lead glass 64 fitted in the notch 23 of the radiation shield layer 22, the lead glass 64 that is most easily damaged in the shield tube 6 and is likely to come off. The film tube can protect against breakage and detachment. This contributes to an improvement in the reuse rate of the shield tube 6 containing lead glass.

  Since the proximal end flange 52 of the syringe 5 is sandwiched between the inward flange 73 of the finger hook cylinder 7 and the proximal end of the shield cylinder 6, detachment from the shield cylinder 6 is reliably prevented. Thereby, the radiation exposure by the syringe 5 inadvertently pulling out from the shield cylinder 6 is prevented.

  Even if the syringe 5 is broken in the packaging protective case 1 and the radioactive solution leaks out from the radioactive solution syringe assembly 4, the water absorbing member 25 absorbs the solution, and therefore the post-processing is easy. .

  A plunger 58 is connected to the piston 53 of the extracted radioactive solution syringe assembly 4, the rubber cap 56 is removed, a double-ended needle (not shown) is inserted through the packing 54, and the subject is injected with the radioactive solution. Is done.

  The shield tube 6 of the radioactive solution syringe assembly 4 prevents radiation exposure to the administration person (doctor). Through the lead glass 64 on the shield tube 6, the remaining amount of the injection solution in the syringe 5 being administered can be visually observed.

The packaging protective case 1 after use is cleaned and prepared for reuse.
The case main body 2 of the packaging protective case 1 has a simple bottomed cylindrical shape as a whole, and the shape of the lid 3 is not complicated. Therefore, the case can be easily cleaned.

  In order to reuse the shield tube 6 of the radioactive solution syringe assembly 4 after use, the syringe 5 is removed from the shield tube 6. For this purpose, the heat shrinkable film tube 8 is first broken and removed, and the holding of the shield cylinder 6 and the finger hook cylinder 7 is released.

Since the heat-shrinkable film tube 8 is provided with intermittent notches 81 and 81 extending in parallel over the entire length of the tube, it can be easily broken.
The finger-clamping cylinder 7 is removed from the shield cylinder 6 to release the restraint of the syringe 5, and the syringe 5 is removed from the shield cylinder 6.
The shield tube 6 is cleaned and prepared for reuse.

  In carrying out the present invention, in order to seal the lid 3 on the case main body 2, an adhesive tape may be wound over the lid 3 and the case main body 2 instead of the heat-shrinkable film tube 82. Even in this case, it is possible to represent a part of the content information by the color of the tape.

  Even when lead globules are used as the packing for the radiation shield layers 22 and 32 of the packaging protection case 1 for the packaging protection case 1 and the radioactive solution syringe assembly 4 of the present invention, the small spheres are not bonded to the resin. Since the resin always adheres to the surface of the small balls by kneading, lead is not directly exposed on the surfaces of the radiation shield layers 22 and 32, and the problem of contamination of lead poisoning does not occur.

  FIG. 4 shows another embodiment. In this embodiment, the inward flange 73 a of the finger hook cylinder 7 is formed as a member independent of the finger hook cylinder 7. The inward flange 73a is detachably coupled to the finger hook cylinder 7 by screwing. In this case, the syringe 5 can be removed from the shield tube 6 simply by removing the inward flange 73a while the finger tube 7 is fitted to the shield tube 6.

  The packaging protective case 1 of the present invention is not limited to housing the radioactive solution syringe assembly 4. Needless to say, the present invention can be implemented in a packaging protective case for storing and transporting radioactive substances contained in containers other than the radioactive solution syringe assembly 4 such as vials.

  It should be noted that the length, thickness, etc. of the radioactive solution syringe assembly of the present invention and its packaging protective case may be as small as possible to prevent radiation leakage. For example, when the outer diameter is 18 mm, the shield cylinder 6 of the syringe assembly 4 can be 2 to 5 mm thick when formed from tungsten, and the lead glass of the shield cylinder 6 can be 5 to 6 mm thick.

  Furthermore, when the outer shells 21 and 31 of the packaging protective case are made of iron, the thickness of these outer shells is 0.5 to 5 mm, and the thickness of the radiation shield layers 22 and 32 is 2 to 10 mm.

  The packaging protective case 1 and the radioactive solution syringe assembly 4 of the present invention can shield radiation without using a lead shielding wall. Even when lead particles are used as the filler of the radiation shield layers 22 and 32 of the packaging protective case 1, the molten resin and lead particles are kneaded and molded, so the lead particles are embedded in the resin. This prevents the lead small particles from being directly exposed on the surfaces of the radiation shield layers 22 and 32, thereby reducing the problem of lead poisoning contamination.

Since the outer shells 21 and 31 are made of metal, the packaging protective case 1 is more resistant to impact force and fire than those of conventional packaging protective cases in which the outer layer is made of resin. It is possible to prevent the case 1 and the radioactive solution syringe assembly 4 from being damaged to the extent that radiation leaks.
Thereby, the reuse rate of packaging protection case 1 can be raised.

  Since the radiation shield layers 22 and 32 of the packaging protective case 1 are formed of a resin in which metal powder or metal particles are kneaded, these layers function as a radiation shield and at the same time a buffer function. Therefore, the packaging protective case 1 does not need to use a cushioning material made of foamed resin as an inner layer as in the prior art, and effectively protects the contained radioactive solution syringe assembly 4 from an impact during transportation.

  In the radioactive solution syringe assembly 4, the heat-shrinkable film tube 8 is put on the finger-clamping tube 7 and the shield tube 6, and the heat-shrinkable film tube 8 is heat-shrinked to hold both in a fixed state. Yes. Therefore, these elements are not inadvertently separated.

  Furthermore, since the heat-shrinkable film tube 8 acts as a film that gives a beautiful appearance and protects the surface of the shield tube 6, it is not necessary to apply silver plating or rust prevention treatment to the surface of the shield tube 6, and correspondingly. Cost reduction is achieved.

  The syringe 5 has its base end flange 52 sandwiched between the inward flange 73 of the finger tube 7 and the base end of the shield tube 6, so that the removal from the shield tube 6 is reliably prevented. Due to this feature, there is no possibility that the syringe 5 will inadvertently come out of the shield tube 6 and the surroundings will be exposed to radiation as in the conventional case.

  After using the syringe assembly 4 to inject the radioactive solution in the syringe 5 into the subject, the syringe 5 is removed from the shield tube 6 to reuse the shield tube 6. The heat shrink film tube 8 is first broken to release the holding of the shield tube 6 and the finger tube 7.

  The finger grip cylinder 7 is removed from the shield cylinder 6, and then the syringe 5 is removed from the shield cylinder 6. A clearance that can be removed without resistance can be provided between the shield tube 6 and the syringe 5, and the radioactive solution syringe assembly 4 can be disassembled without difficulty.

It is sectional drawing of the state which accommodated the radioactive solution syringe assembly in the packaging protection case. It is sectional drawing which follows the AA line of FIG. It is a slope view of the finger tube which fractured | ruptured a part. It is a perspective view of the other Example of a finger hook cylinder. It is sectional drawing of the conventional case main body and a radioactive solution syringe assembly.

Explanation of symbols

2 Case body 3 Lid 4 Radioactive solution syringe assembly 5 Syringe 6 Shield tube 7 Finger tube 8 Heat-shrinkable film tube 21 Outer shell 22 Radiation shield layer 31 Outer shell 64 Lead glass

Claims (1)

  The syringe (5) holding the radioactive solution is accommodated in the radiation shield tube (6), and the finger-clad tube (7) including the finger-hook piece (71) at the time of injection is attached to the proximal end of the shield tube (6). In the radioactive solution syringe assembly (4), the finger tube (7) has an inward flange (73) at the proximal end, and between the inward flange (73) and the proximal end of the shield tube (6). The flange (52) provided at the proximal end of the syringe (5) is sandwiched, and the heat-shrinkable film tube (8) is tightly covered in a contracted state across the shield tube (6) and the finger tube (7). A radioactive solution syringe assembly characterized by that.

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