JPH10314203A - Skin protective material - Google Patents

Abstract

PROBLEM TO BE SOLVED: To improve the sealing of the skin, make a skin protective material hard to cause a rash, make it unflowing, and prevent paste from remaining on the skin at time of releasing by integrally laminating a hydrophilic pressure sensitive adhesive mainly composed of an elastic polymer and a water soluble high polymer on one surface of a hydrophobic pressure sensitive adhesive mainly composed of an elastic polymer. SOLUTION: This skin protective material is formed as a two-layer structure by integrally laminating a hydrophilic pressure sensitive adhesive 1 on one surface of a hydrophobic pressure sensitive adhesive 3, and is desirably obtained by integrally laminating the hydrophilic pressure sensitive adhesive 1 on the hydrophobic pressure sensitive adhesive 3 on which a creep has cohesive power not more than 5 mm/hour (JISZ-0237). This hydrophilic pressure sensitive adhesive 1 is obtained by uniformly mixing an elastic polymer and a water soluble high polymer, in a word, a medicine or the like by a kneader. Next, an obtained mixture is rolled in a sheet shape by a T die extruder, a rolling roller and a press machine, and is stuck to the protective material 2 of the hydrophilic pressure sensitive adhesive composed of a mold parting processed plastic film and mold releasable paper simultaneously with rolling or after rolling.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION The present invention relates to a stoma, a fistula or an opening (hereinafter referred to as a stoma) of a person having a colostomy or an artificial bladder, and excrement does not directly contact the skin or does not contact the skin. The present invention also relates to a skin protective material capable of suppressing dermatitis and rash or a skin protective material capable of being applied to an ulcer surface such as a pressure ulcer to protect a sore wound.

[0002]

Heretofore, those who have undergone artificial ostomy surgery have been wearing various pouches (bags) for storing excrement from the stoma. As a means for attaching this pouch to the skin surface around the stoma, a ring or washer made of a water-swellable substance (hydrophilic substance) such as karaya-glycerol gel or carboxymethyl cellulose is used. Disadvantages of these rings or washers are that they have low adhesion to the skin, making it difficult to maintain airtightness, and that due to the poor airtightness, the excrement from the stoma comes into direct contact with the skin. It causes inflammation and rash.

[0003] Various attempts have been made to prevent this disadvantage. For example, JP-A-54-44
No. 91 discloses a medical binder comprising a mixture of a hydrocolloid and a mineral oil, a pressure-sensitive adhesive component which is an adhesive strength enhancer such as finely divided cellulose, insoluble cross-linked dextran, and Na-CMC.

[0004] However, although this medical bonding agent is improved in hermeticity, it is poor in elasticity and cannot keep up with the body movement, so that it has a drawback in that wrinkles are formed during use and the part breaks due to hip break. In addition, there is a drawback that the fluid flows during storage or use and cannot achieve its intended purpose.

Further, Japanese Patent Application Laid-Open No. 57-169414 (Japanese Patent Publication No. 63-6020) discloses a method of improving the flowability of an adhesive rubber-like bonding agent, a hydrocolloid (hydrocolloid), and white carbon or calcium carbonate. A skin protector made of a mixture of humans is disclosed.

However, since this skin protective material is made of an adhesive rubber-like bonding agent obtained by blending (kneading) a hydrocolloid (hydrocolloid), an elastic binder insoluble in water, and a flow inhibitor, Although the hardness and adhesive strength can be improved, there is a disadvantage that the fluidity is large. If a large amount of a flow inhibitor is added to improve the fluidity, the hardness becomes high and the elasticity is poor, and the body movement cannot be kept.To prevent this, the amount of the flow inhibitor must be kept constant. However, there is a limit to the improvement of liquidity, for example, the improvement in liquidity is small.

Further, JP-A-1-99564 discloses that a support material such as a polymer film, a woven fabric, a nonwoven fabric, or a polymer foam comprises a pressure-sensitive material comprising a mixture of an elastic binder, a water-swellable substance and a pharmaceutically active ingredient. A pharmaceutically active ingredient-containing adhesive bandage for protecting a sore wound surface attached to one surface of an adhesive layer is disclosed.

However, the pressure-sensitive adhesive layer of this pressure-sensitive adhesive bandage is disclosed in JP-A-57-169414 (JP-B-63-602).
No. 0), it is a composition obtained by blending (kneading) a water-swellable substance (water-soluble polymer) and a hydrophobic elastic adhesive substance. Compared with those consisting only of a karaya composition of a hydrocolloid substance or a hydrocolloid substance, the adhesive strength is improved and it is easier to follow body movements, so the sealing property to the swelling surface is improved, but the adhesive layer contains a hydrophilic substance, Cannot completely prevent the fluidity, softening and stickiness of the skin, and have the disadvantage that the adhesive remains on the acne surface and the skin around the stoma even after the bandage is removed.

The present invention provides the functions required for the above-mentioned skin protection materials for stoma and acne, that is, it has good sealing properties to the skin, is hardly fogged, hardly flows, It is an object of the present invention to obtain a skin protection material having all that no glue remains on the skin.

[0010]

SUMMARY OF THE INVENTION According to the present invention, there is provided a flexible adhesive having an elastic polymer and a water-soluble polymer as its main components on one surface of a hydrophobic adhesive material having an elastic polymer as a main component and a large cohesive force. Using a skin protection material formed by integrally laminating a hydrophilic pressure-sensitive adhesive into a two-layer structure, and taking a measure of sticking the hydrophilic pressure-sensitive adhesive surface of the skin protection material to the acne surface and the skin around the stoma. The hydrophilic adhesive, which has flexibility, adhesion and water absorption, enhances the adhesion to the swelling surface and the skin around the stoma, and can be firmly adhered even after long-term use. It does not absorb the secretion of the surrounding skin and becomes a culture medium of bacteria, and it is easy to follow body movements and does not give physical irritation to the skin surface, so it is difficult to fog, and a hydrophilic adhesive is integrally laminated Hydrophobic adhesive is hydrophilic due to its cohesive strength Holding the adhesive prevents adhesive residue on the skin by disruption of the hydrophilic pressure sensitive adhesive during the peeling, it can be easily peeled off the skin protective material.

[0011]

Embodiments of the present invention will be described below in detail with reference to the drawings. FIG. 1 is a perspective view showing an example of the skin protective material of the present invention in which a hydrophilic pressure-sensitive adhesive is laminated on one side of a hydrophobic pressure-sensitive adhesive. FIG. 2 is a perspective view showing a hydrophilic pressure-sensitive adhesive containing a cloth or nonwoven fabric. FIG. 3 is a perspective view showing an example of the skin protective material of the present invention in which an adhesive is laminated, and FIG. 3 is a hydrophilic adhesive having a surface area smaller than that of the hydrophobic adhesive at a desired position except a peripheral portion on one surface of the hydrophobic adhesive. FIG. 4 is a perspective view showing an example of the skin protective material of the present invention in which a hydrophilic pressure-sensitive adhesive having a smaller surface area than the hydrophobic pressure-sensitive adhesive is laminated at a desired portion except a peripheral portion on one surface of the hydrophobic pressure-sensitive adhesive. FIG. 5 is a perspective view showing an example of the skin protective material of the present invention in which a therapeutic material is further laminated on a hydrophilic adhesive, and FIG. 5 is a skin protective material of the present invention in which a hydrophobic adhesive and a hydrophilic adhesive are provided with a plurality of grooves. FIG. 6 is a perspective view showing an example of the present invention. FIG. FIG. 7 is a perspective view showing an example of the skin protective material of the present invention in which a hole having a desired diameter is provided through a hydrophobic adhesive and a hydrophilic adhesive in a substantially central portion of the portion, and FIG. FIG. 8 is a diagram showing an example of use of the skin protector of the present invention for protecting a sore wound, and FIG. 8 is a diagram showing an example of use of the skin protector of the present invention attached to a pouch (bag).

In the drawings, 1 is a hydrophilic adhesive, 1a is a plurality of grooves provided in the hydrophilic adhesive 1, 2 is a protective material for the hydrophilic adhesive, 3 is a hydrophobic adhesive, and 3a is a hydrophobic adhesive. A plurality of grooves provided in the material 3, 3 b is a cloth or non-woven fabric existing in the hydrophobic adhesive 3, 4 is release paper, 5 is a protective material of the hydrophobic adhesive, 6 is a hydrophilic adhesive 1 and hydrophobic adhesive A hole penetrating the material 3, 7 is a pouch (bag), 8 is a deodorant hole, 9 is an identification tag, and 10 is a treatment material.

That is, the present invention is a skin protective material formed by integrally laminating a hydrophilic pressure-sensitive adhesive 1 on one side of a hydrophobic pressure-sensitive adhesive 3 to form a two-layer structure as shown in FIGS. .

Preferably, the present invention relates to a skin protective material comprising a hydrophobic adhesive 3 having a cohesive force of 5 mm / hour or less (JISZ-0237) at 20 ° C. and a hydrophilic adhesive 1 laminated integrally. And, unlike the conventional use of a hydrophilic adhesive alone, such a skin protection material loses its shape even when it absorbs the secretion fluid, sticks more than necessary, and has excessive flow. Starting to do
All of the drawbacks such as losing its cohesive force when peeled off and remaining on the skin can be overcome.

That is, the hydrophilic pressure-sensitive adhesive 1 having a generally weak cohesive force
When the skin protective material consisting only of the adhesive is applied to the wound or the area around the stoma, the hydrophilic pressure-sensitive adhesive 1 is applied due to a rise in temperature due to body temperature, absorption of secretions, or a slight tension at the time of application.
Tend to soften, lose their shape, flow, or sticky.

However, when the skin protective material has the following two-layer structure, that is, the pressure-sensitive adhesive constituting one layer has a temperature of 20 ° C.
Creep of 5mm / hour or less (JISZ-0237)
Is a hydrophobic pressure-sensitive adhesive 3 having a cohesion force much larger than the cohesion force of the hydrophilic pressure-sensitive adhesive 1 which is the other layer, and the hydrophilic pressure-sensitive adhesive is in any case where the adhesion force between the two layers is any. When a two-layer structure is integrally laminated so as to be larger than that between the first adhesive and the adherend, the hydrophobic adhesive 3 has a flexibility enough to follow the hydrophilic adhesive 1 to the skin. The elastic pressure-sensitive adhesive can be elastically fixed while maintaining the same, so that the softening of the hydrophilic pressure-sensitive adhesive 1, the loss of shape, and excessive flow can be suppressed. Further, at the time of peeling, the hydrophilic pressure-sensitive adhesive 1 is pulled up toward the hydrophobic pressure-sensitive adhesive having a large cohesive force, and can be easily peeled off without causing adhesive residue on the adherend.

Here, the hydrophobic adhesive 3 is made of NR,
IR, BR, IIR, EPR, CR, NBR, SBR,
Rubbers such as polyisobutylene, acrylics such as alkyl acrylate copolymers and ethylene methyl acrylate copolymers, silicones such as dimethylsiloxane, methylvinylsiloxane, phenylmethylsiloxane, phenylvinylmethylsiloxane, and fluorosilicone;
Urethanes such as polyester urethane and polyether urethane, vinyl acetates such as ethylene vinyl acetate copolymer and vinyl acetate copolymer, SBS, SIS, SEB
S, SEPS, polyester urethane, polyether urethane, polyether polyester block copolymer,
Thermoplastic rubbers such as polyolefin block copolymer, trans 1.4 polyisoprene, polyethylene butyl graft copolymer, polybutadiene, polychloroprene,
It can be obtained by adding an elastic polymer selected from liquid rubbers such as polyisoprene, poly1.3 pentadiene, polycyclopentadiene, and polybutene as a main component, and adding a tackifier, a filler, a pigment, and the like, if necessary.

Further, the hydrophobic adhesive 3 may be any of a solvent type, an aqueous type, a liquid polymer type, a dry blend type (sealant type) and a hot melt type, and is subjected to a release treatment according to each type. Is coated, extruded, pressed, and rolled (calendering) on the protective material 5 of a hydrophobic adhesive material made of a plastic film or release paper, or is bonded to the protective material 5 after coating, extruding, pressing, and rolling. Or transcribed.

On the other hand, the shape of the hydrophobic pressure-sensitive adhesive material 3 thus obtained is such that the original shape is a sheet shape, a tape shape, and a film shape, and is bonded to the hydrophilic pressure-sensitive adhesive 1 which is another layer. It can be formed into a desired shape such as a square, a polygon, a trapezoid, a rectangle, a circle, and an ellipse by a method such as punching, pressing, or cutting.

Further, the thickness of the thus obtained hydrophobic adhesive material 3 is desirably 2 mm to 0.02 mm.
The reason for this is that if the thickness is 2 mm or more, the hydrophobic adhesive 3 itself may lose its shape or flow due to its own weight or external pressure. Is difficult to obtain adhesive strength,
A force for elastically fixing the hydrophilic pressure-sensitive adhesive 1 while keeping the softness, the shape loss and the excessive flow of the hydrophilic pressure-sensitive adhesive 1 on the skin, and the application to the pouch (bag) 7 shown in the usage example of FIG. This is because the adhering force, and further, the adhering force for attaching the identification tag 9 in FIG. 7 may be weakened, which may cause a problem.

Next, the hydrophilic pressure-sensitive adhesive 1 will be described.
Examples of the composition of the hydrophilic pressure-sensitive adhesive 1 include an elastic polymer used for the above-mentioned hydrophobic pressure-sensitive adhesive 3 and karaya gum, guar gum, gum arabic, carob gum, rockast bean gum, carrageenan, starch, pectin, gelatin, albumin, and sodium. One of natural water-soluble polymers such as carboxymethylcellulose, calcium carboxymethylcellulose, carboxymethylcellulose, microcrystalline cellulose, xanthan gum, etc., and synthetic water-soluble polymers such as polyacrylic acid, polyvinyl alcohol, polyethylene oxide, sodium alginate and calcium alginate One or more than one.

The mixing ratio between the elastic polymer and the water-soluble polymer is preferably from 3: 7 to 7: 3. This is because water-soluble polymers with a mixing ratio of 70% or more tend to soften unnecessarily due to body temperature or absorption of secretions, and are easily sticky, while those with a mixing ratio of 30% or less have too large a cohesive force to the skin. This is not preferable because, in addition to the poor adhesion, the secretion fluid is absorbed and it is difficult to follow the body movement.

On the other hand, the hydrophilic pressure-sensitive adhesive 1 is obtained by uniformly mixing an elastic polymer and a water-soluble polymer, if necessary, with a kneading machine such as a kneader. The resulting mixture is
Next, the sheet is rolled into a sheet by a T-die extruder, a rolling roll, or a press, and bonded to the protective material 2 of a hydrophilic pressure-sensitive adhesive made of a release-treated plastic film or release paper simultaneously with or after rolling. .

The thickness of the thus obtained hydrophilic pressure-sensitive adhesive 1 is preferably 0.5 mm to 3 mm. This is because when the hydrophilic pressure-sensitive adhesive 1 has a thickness of 0.5 mm or less, a pouch (bag) is attached to the skin surface around the stoma so that excrement from the stoma does not directly contact the skin and does not leak to the outside. This is because it is difficult to fulfill the original purpose of the skin protection material for use in attaching to a stoma, which is to be stored in a (bag). If the thickness is 3 mm or more, excessive flow is likely to occur. This is because it has disadvantages such as a great sense of discomfort.

Next, in the lamination of the hydrophilic pressure-sensitive adhesive 1 and the hydrophobic pressure-sensitive adhesive 3, these two pressure-sensitive adhesives can be simultaneously bonded by using a composite extruder, or separately formed and bonded. After the square, polygon, trapezoid, rectangle,
It can be formed in a desired shape such as a circle or an ellipse.
In addition, it is also possible to form them by bonding them after processing them into a desired shape, as long as they can form a two-layer structure in which these two adhesives are integrally laminated in a desired shape. Either is acceptable.

As a measure to prevent the hydrophilic pressure-sensitive adhesive 1 from protruding from the surface of the hydrophobic pressure-sensitive adhesive 3 due to excessive flow of the hydrophilic pressure-sensitive adhesive 1 and thereby deteriorating the releasability from the adherend, FIGS. As shown in FIG. 4, the hydrophobic pressure-sensitive adhesive 3 has a surface area larger than the surface area of the hydrophilic pressure-sensitive adhesive 1, that is, the hydrophobic pressure-sensitive adhesive 3 is provided at a desired position except a peripheral portion on one side of the hydrophobic pressure-sensitive adhesive 3. The hydrophilic pressure-sensitive adhesive 1 having a surface area smaller than the surface area of No. 3 may be integrally laminated to form a two-layer structure. In this way, the hydrophilic pressure-sensitive adhesive 1 can be easily held by the hydrophobic pressure-sensitive adhesive 3, and even if the hydrophilic pressure-sensitive adhesive 1 causes excessive flow due to the temperature or the absorption of secretion fluid, it is not hydrophobic. It does not protrude outside the area of the adhesive 3.

On the other hand, in order to further enhance the above-described effects of the hydrophobic adhesive 3, a nonwoven fabric or a cloth 3b can be included in the hydrophobic adhesive 3 as shown in FIGS. . By doing so, the cohesive force of the hydrophobic pressure-sensitive adhesive 3 is supplemented, and the excessive fluidity of the hydrophilic pressure-sensitive adhesive 1 and the good peelability at the time of peeling can be further enhanced.

Further, according to the skin protective material of the present invention when used for the purpose of protecting a sore area, as shown in FIG. 4, an anti-inflammatory analgesic, a local anti-inflammatory, A therapeutic material 10 such as a gauze impregnated with an agent such as an antipruritic, an anti-scabies agent, a local anesthetic, an antibacterial agent, or the like can also be used by attaching. Further, the above-mentioned drug can be directly kneaded into the hydrophilic adhesive 1, but in this case, the treatment material 10 such as gauze can be omitted. Furthermore, for applications requiring air permeability, both the hydrophilic pressure-sensitive adhesive 1 and the hydrophobic pressure-sensitive adhesive 3 or only the hydrophilic pressure-sensitive adhesive 1 is 300 g / m ^2.
· Moisture permeability of 24 hours ~8000g / m ² · 24 hours is designed to give. This is 300 g / m ² · 24
Insufficient moisture permeability in the time following moisture permeability, is because not enough play a moisture permeation function, 8000g / m ² · 24
This is because moisture permeability for more than an hour is not preferable because it rather causes moisture absorption in the atmosphere. In order to obtain the above-mentioned moisture permeability, the hydrophilic pressure-sensitive adhesive 1 or the hydrophobic pressure-sensitive adhesive 3 is mechanically provided with pores, or is heated and dried by adding a hydrophilic polymer aqueous solution to the composition. Obtainable.

Further, as shown in FIG. 5, the skin protective material of the present invention has a plurality of grooves on each of the surface to be adhered to the skin around the stoma and the hydrophobic adhesive 3 and / or the hydrophilic adhesive 1 or both. 1a and 3a can be provided. This is partly to reduce the contact area to the skin surface to be adhered and to facilitate peeling, and to release excess flow of the adhesive in the thickness direction to protrude in the width and length directions. This is to prevent it.

Further, as shown in FIG. 7, in an application for sticking to the swelling surface and protecting the swelling portion, the protective material 5 made of a hydrophobic adhesive material is peeled off after the application to the swelling portion and the identification tag is obtained. Paste 9
The identification can be used after the identification is clarified, or a desired identification display can be printed on the protective material 5 made of a hydrophobic adhesive material and used as the identification tag 9.

On the other hand, as shown in FIG. 8, after the pouch (bag) is attached, the pouch (bag) is attached to the skin surface around the stoma, for example, as shown in FIG. A hole 6 having a desired diameter penetrating the hydrophobic pressure-sensitive adhesive 3 and the hydrophilic pressure-sensitive adhesive 1 is provided substantially at the center of the portion where the hydrophobic pressure-sensitive adhesive 3 and the hydrophilic pressure-sensitive adhesive 1 are integrally laminated. This hole 6 must of course be connected to a hole in the pouch (bag) and to a stoma.

The skin protective material shown in FIGS. 3 to 6 is adhered to the skin surface by peeling off the release material 4 provided on the protective material 2 of the hydrophilic adhesive and the hydrophobic adhesive 3. I do.

[0033]

Embodiments of the present invention will be described below. Example 1 A hydrophilic pressure-sensitive adhesive component shown in Table 1 and a hydrophobic pressure-sensitive adhesive component shown in Table 2 were mixed in a kneader. Next, each of the compounded hydrophilic pressure-sensitive adhesive composition and hydrophobic pressure-sensitive adhesive composition was sheeted with an extruder to a thickness of 1 mm, and then 25 cm × 25 mm.
After cutting into a size of 1 cm and bonding them together with a pressure press machine, a sample 1 was obtained by punching to 150 mmφ. When this sample 1 was used for trial, the results shown in Table 3 were obtained.

Example 2 A sheet-shaped hydrophilic pressure-sensitive adhesive was prepared in the same manner as in Example 1, and then punched into a 150 mmφ circle. Next, a 30 μm thick acrylic pressure-sensitive adhesive was coated on a protective material (kraft release paper) to prepare a hydrophobic pressure-sensitive adhesive, and a 150 mmφ punched hydrophilic pressure-sensitive adhesive was continuously formed on the hydrophobic pressure-sensitive adhesive. And then 170mm
Sample 2 was obtained by punching into φ. When this sample 2 was used for trial, the results shown in Table 3 were obtained.

[0035]

[Table 1]

[0036]

[Table 2]

[0037]

[Table 3]

As can be seen from the results in Table 3, Sample 1 and Sample 2 each had a good hydrophilic adhesive with low fluidity and no adhesive residue and no fogging.

[0039]

EFFECT OF THE INVENTION The skin protective material of the present invention is a hydrophilic pressure-sensitive adhesive having flexibility, adhesiveness and water absorption, which enhances the adhesiveness to the swelling surface and the skin around the stoma so that it can be securely adhered even when used for a long period of time. It can also absorb secretions from the skin around the acne surface and stoma and does not become a culture medium for bacteria, and it is easy to follow body movements and does not give physical irritation to the skin surface, so it is less rash, Hydrophobic pressure-sensitive adhesive laminated with hydrophilic pressure-sensitive adhesive is elastically fixed by its cohesive force while maintaining flexibility enough to follow the skin, and excessive flow of hydrophilic pressure-sensitive adhesive In addition, the effect that the skin protective material can be easily peeled off without causing adhesive residue on the skin due to the destruction of the hydrophilic adhesive due to the retention of the cohesive force at the time of peeling can be obtained.

[Brief description of the drawings]

FIG. 1 is a perspective view showing an example of the skin protective material of the present invention in which a hydrophilic adhesive is laminated on a hydrophobic adhesive.

FIG. 2 is a perspective view showing an example of the skin protective material of the present invention in which a cloth or a nonwoven fabric is embedded in a hydrophobic adhesive.

FIG. 3 is a perspective view showing an example of the skin protection material of the present invention in which a hydrophilic adhesive having a smaller surface area than the adhesive is laminated on a hydrophobic adhesive.

FIG. 4 is a perspective view showing an example of the skin protective material of the present invention in which a treatment material is laminated on the hydrophilic adhesive of the skin protective material of FIG.

FIG. 5 is a perspective view showing an example of the skin protective material of the present invention in which a plurality of grooves are provided in a hydrophobic adhesive and a hydrophilic adhesive.

FIG. 6 is a perspective view showing an example of the skin protective material of the present invention provided with a hole penetrating a hydrophobic adhesive and a hydrophilic adhesive.

FIG. 7 is a view showing an example of use of the skin protective material of the present invention which is adhered to an acne surface to protect an acne wound.

FIG. 8 is an application example diagram of the skin protective material of the present invention attached to a pouch (bag).

[Explanation of symbols]

 REFERENCE SIGNS LIST 1 hydrophilic adhesive 1a groove provided in hydrophilic adhesive 2 protective material for hydrophilic adhesive 3 hydrophobic adhesive 3a groove provided in hydrophobic adhesive 3b fabric or non-woven fabric inherent in hydrophobic adhesive 4 release Paper 5 Protective material for hydrophobic adhesive material 6 Hole penetrating hydrophilic adhesive and hydrophobic adhesive material 7 Pouch (bag) 8 Deodorant hole 9 Identification tag 10 Treatment material

──────────────────────────────────────────────────の Continued on the front page (51) Int.Cl. ⁶ Identification code FI B32B 7/10 B32B 25/08 25/08 A61L 15/01 (72) Inventor Keiichiro Shiga 3-20 Tachibana, Nishinari-ku, Osaka-shi, Osaka No. 28 Kyowa Corporation (72) Inventor Kazuo Matsuoka 3-20-28 Tachibana, Nishinari-ku, Osaka City, Osaka Prefecture Kyowa Corporation

Claims (8)

[Claims] 1. A two-layer structure in which an elastic polymer and a hydrophilic adhesive mainly containing a water-soluble polymer are integrally laminated on one surface of a hydrophobic adhesive mainly containing an elastic polymer. A skin protection material characterized by the following. 2. The method according to claim 1, wherein the hydrophobic adhesive is rubber-based, acrylic-based,
Adhesive material mainly composed of silicone-based, urethane-based, vinyl acetate-based, thermoplastic rubber-based, and liquid rubber-based elastic polymers and having a cohesive strength of 5 mm / hour or less at 20 ° C. The skin protective material according to claim 1, 3. The skin protective material according to claim 1, wherein the hydrophobic adhesive is an adhesive containing a fabric or a nonwoven fabric. 4. A therapeutic material such as a gauze impregnated with an anti-inflammatory analgesic agent, a local anti-inflammatory agent, an antipruritic agent, an anti-scabies agent, a local anesthetic agent, an anti-bacterial agent or the like is stuck on the hydrophilic adhesive. The skin protective material according to any one of claims 1 to 3, wherein the agent is kneaded in a hydrophilic adhesive. 5. 300 g / m ² · 24 hours to 8000 g
The skin protective material according to any one of claims 1 to 4, wherein a moisture permeability of / m ² · 24 hours is applied to both the hydrophobic adhesive and the hydrophilic adhesive or only the hydrophilic adhesive. . 6. A two-layer structure in which a hydrophilic pressure-sensitive adhesive having a surface area smaller than the surface area of the hydrophobic pressure-sensitive adhesive is integrally laminated at a desired position except a peripheral portion on one surface of the hydrophobic pressure-sensitive adhesive. The skin protective material according to any one of claims 1 to 5, wherein: 7. The method according to claim 1, wherein a plurality of grooves are provided on a surface of the hydrophobic adhesive or the hydrophilic adhesive, or both of them, which is adhered to the sore surface or the skin around the stoma. The skin protective material according to any one of the above. 8. A hole having a desired diameter penetrating the hydrophobic pressure-sensitive adhesive and the hydrophilic pressure-sensitive adhesive is provided substantially at the center of a portion where the hydrophobic pressure-sensitive adhesive and the hydrophilic pressure-sensitive adhesive are integrally laminated. The skin protective material according to any one of claims 1 to 7, wherein: