JPH0987673A - Detergent composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a detergent composition having low stimulation to the skin and high detergency, excellent in bactericidal effect and durability, good in feeling in use and especially suitable for a liquid detergent for body. SOLUTION: This detergent composition contains (A) 5-90wt.% glycine derivative of formula I (R<1> is a 5-21C alkyl, alkenyl or hydroxyalkyl) (a salt such as an slkali metal salt, a trialkanol amine salt, a basic amino acid salt, etc.), (B) 0.05-3wt.% cationic bactericidal agent and further, if needed, (C) a metal chelating agent in 0.5-3 mole times as much as the ingredient B. As an example of the ingredient B, a benzarconium salt of formula II (R<2> is an 8-24C hydrocarbon; Z is a halogen, an amino acid, a fatty acid, etc.) can be cited.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a detergent composition, and more particularly to a detergent composition which is mild to the skin, has a high detergency, is excellent in bactericidal effect and its durability, and has a good feeling in use. It relates to a composition.

[0002]

2. Description of the Related Art Conventionally, as a germicidal detergent, a medicated detergent containing various surfactants and germicides in combination has been known. However, when a disinfectant is added to a cleaning agent, the disinfectant itself is washed away from the skin or hair by cleaning and does not remain sufficiently, and its effect is almost eliminated against bacteria that adhere to the skin or hair after cleaning. There was a problem that it could not be demonstrated.

Therefore, in order to enhance the bactericidal effect of the detergent, a method of increasing the amount of the bactericidal agent blended can be considered, but it is not preferable due to the concern of skin irritation, allergies, etc., and the effect is also temporary. Although it increased, there was also a problem that it was not sufficient and sustainability was poor.

[0004]

SUMMARY OF THE INVENTION Accordingly, the object of the present invention is to provide a detergent composition which is mild to the skin, has high detergency, is excellent in bactericidal effect and its durability, and has a good feeling in use. To provide.

[0005]

Means for Solving the Problems As a result of intensive studies in view of such circumstances, the present inventors have found that when a specific glycine derivative and a cationic bactericide are used in a specific ratio, they are hypoallergenic to the skin. It was found that a detergent composition having a high detergency, an excellent bactericidal action and its durability, and a good feeling during and after washing can be obtained, and the present invention has been completed.

That is, the present invention provides the following components (A) and (B): (A) General formula (1)

[0007]

Embedded image

(Wherein R ¹ represents a linear or branched alkyl group, alkenyl group or hydroxyalkyl group having 5 to 21 carbon atoms) or a salt thereof in an amount of 5 to 90% by weight, (B ) Cationic fungicides
The present invention provides a detergent composition containing 0.05 to 3% by weight.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION The component (A) used in the present invention is a glycine derivative represented by the general formula (1) or a salt thereof. In the formula, examples of the linear or branched alkyl group, alkenyl group, or hydroxyalkyl group having 5 to 21 carbon atoms represented by R ¹ include, for example, n-pentyl group, n-heptyl group, n-octyl group, n- Nonyl group, n-decyl group,
Examples include n-undecyl group, n-dodecyl group, n-tridecyl group, n-tetradecyl group, n-pentadecyl group, n-heptadecyl group, methylhexadecyl group, ethylpentyl group, heptadecenyl group and hydroxyundecyl group. . Of these, carbon number 7 to
The alkyl group and alkenyl group having 19 carbon atoms are preferable, and those having 9 to 15 carbon atoms are particularly preferable.

The salt of the glycine derivative represented by the general formula (1) is, for example, an alkali metal salt, an alkaline earth metal salt, an ammonium salt, a mono-, di- or trialkanolamine salt having 1 to 22 total carbon atoms, 1 to 22 carbon atoms
Alkyl group or alkenyl group-substituted pyridinium salt, a polyalkylene polyamine salt having a total carbon number of 2 to 500 and a total amino number of 2 to 250, a basic amino acid salt, and the like,
For example, sodium salt, potassium salt, magnesium salt, calcium salt, ammonium salt, monoethanolamine salt, diethanolamine salt, triethanolamine salt,
Examples thereof include ethylenediamine salt, propylenediamine salt, arginine salt, histidine salt and lysine salt. Of these, alkali metal salts, trialkanolamine salts,
Basic amino acid salts are preferable, and sodium salt, potassium salt, triethanolamine salt, arginine salt, and sodium salt and potassium salt are particularly preferable.

The salt of the glycine derivative represented by the general formula (1) does not necessarily have to be added as a salt, and the glycine derivative and a base forming such a salt are separately added and the composition is prepared. The salt may be formed therein. Examples of bases that form such salts include alkali metal hydroxides, alkaline earth metal hydroxides, ammonia, mono-, di- or trialkanolamines having 1 to 22 carbon atoms, and alkyl groups having 1 to 22 carbon atoms. Or alkenyl group-substituted pyridine, total carbon number 2 to 500 and total amino number 2 to
500 polyalkylene polyamines, basic amino acids and the like are listed, for example, sodium hydroxide, potassium hydroxide, magnesium hydroxide, calcium hydroxide, ammonia, monoethanolamine, diethanolamine, triethanolamine, ethylenediamine, propylenediamine, arginine, Histidine, lysine, etc. are mentioned.

The component (A) is N-lauroyl-N.
-Carboxyethylglycine sodium salt, N-lauroyl-N-carboxyethylglycine potassium salt, N-
Lauroyl-N-carboxyethylglycine triethanolamine salt, N-myristoyl-N-carboxyethylglycine sodium salt, N-myristoyl-N-carboxyethylglycine potassium salt, N-myristoyl-
N-carboxyethylglycine triethanolamine salt, N-myristoyl-N-carboxyethylglycine arginine salt, N-coconut oil fatty acid acyl-N-carboxyethylglycine sodium salt, N-coconut oil fatty acid acyl-N-carboxyethylglycine potassium salt Salt is preferred.

Such a glycine derivative (1) or a salt thereof can be produced, for example, according to the reaction formula shown below.

[0014]

Embedded image

That is, glycine represented by the general formula (3) or a salt thereof is reacted with acrylonitrile to obtain a glycine derivative (4) or a salt thereof (step A), which is hydrolyzed and, if necessary, a salt. Glycine derivative (7) or a salt thereof is obtained by exchanging (step B), and then this is reacted with acid chloride (5), and salt exchange is carried out if necessary (step E) to give glycine as the component (A). Derivative (1)
Alternatively, its salt can be obtained. Further, the glycine derivative (4) or salt thereof obtained in step A is reacted with an acid chloride (5), and if necessary, salt exchange is performed to obtain a glycine derivative (6) or salt thereof (step C), Then, the glycine derivative (1) as the component (A) or a salt thereof can be obtained by hydrolyzing the salt and exchanging the salt as necessary (step D).

Each step will be described below. (Step A) This step is a step of reacting glycine (3) or a salt thereof with acrylonitrile to obtain a glycine derivative (4) or a salt thereof. Glycine or a salt thereof as a raw material, and acrylonitrile may be produced by known methods, any commercially available one may be used, but if necessary, recrystallization, purification by distillation, etc. You may use.

Specific examples of glycine (3) or a salt thereof include glycine, glycine sodium salt, glycine potassium salt, glycine lithium salt, glycine magnesium salt,
Glycine calcium salt, glycine ammonium salt, glycine ethylenediamine salt, glycine propylenediamine salt and the like can be mentioned, and glycine sodium salt, glycine potassium salt and glycine ammonium salt are particularly preferable.

In this step, glycine (3) or a salt thereof and 0.5 to 10 equivalents of acrylonitrile are added in water at a suitable temperature of 10 to 100 ° C., preferably 30 to 70 ° C., and 0.5 to 100. The glycine derivative (4) or a salt thereof can be obtained by reacting for a time, preferably 1 to 3 hours, and if necessary, by exchanging a counter ion with an electrodialyzer or the like. When the reaction time is longer than 100 hours, side reactions such as hydrolysis of the cyano group occur concurrently, which is not preferable. During the reaction, it is preferable that a treatment such as gradually adding acrylonitrile to an aqueous solution of glycine (3) or a salt thereof is performed because side reactions such as polymerization of acrylonitrile are significantly suppressed and the yield is improved. The glycine derivative (4) or a salt thereof obtained in this step can be used as it is in the next step, but if necessary, it may be recrystallized using a solvent such as water, methanol, ethanol, etc. It can also be a product.

(Step B) In this step, the cyano group of the glycine derivative (4) or salt thereof obtained in step A is hydrolyzed, preferably in the presence of a basic substance, to give a glycine derivative (7) or its salt. This is the step of obtaining salt. Examples of the basic substance used here include alkali metal hydroxides and alkaline earth metal hydroxides, and specific examples include sodium hydroxide, potassium hydroxide, magnesium hydroxide,
Examples thereof include calcium hydroxide and barium hydroxide.

In this step, the glycine derivative (4)
Or a salt thereof in the presence of 0.1 to 30 equivalents of a basic substance,
In an aqueous solution, if necessary, water and methanol, ethanol,
In a mixed solution with a polar solvent such as isopropanol, acetone, 1,3-propanediol, and propylene glycol, the reaction is carried out at a suitable temperature of 50 to 100 ° C., preferably 70 to 100 ° C. for 0.5 to 100 hours, If necessary, by exchanging counterions with an electrodialyzer,
Glycine derivative (7) or a salt thereof can be obtained.
The glycine derivative (7) or its salt obtained in this step can be used as it is in the next step, but if necessary, recrystallization is performed using a solvent such as water, methanol, ethanol, etc. It can also be a product.

(Step C) In this step, the glycine derivative (4) or salt thereof obtained in step A is reacted with an acid chloride (5), preferably in the presence of an alkaline substance, to give a glycine derivative (6) or This is the step of obtaining the salt. As the acid chloride (5) as a raw material, any of those produced by a known method and those commercially available may be used, but those obtained by purification such as distillation may be used if necessary.
Specific examples of the acid chloride (5) include hexanoic acid chloride, octanoic acid chloride, decanoic acid chloride,
Dodecanoic acid chloride, tetradecanoic acid chloride, hexadecanoic acid chloride, octadecanoic acid chloride,
Examples thereof include fatty acid chlorides having a single composition such as 2-ethylhexanoic acid chloride, isostearic acid chloride and oleic acid chloride, and fatty acid chlorides having a mixed composition such as coconut oil fatty acid chloride and tallow fatty acid chloride.

In this step, the glycine derivative (4)
Or its salt and 0.8-5.0 equivalent normally, Preferably it is 0.
9 to 1.3 equivalents of acid chloride (5) in an aqueous solution,
If necessary, in a mixed solution of water and a polar solvent such as methanol, ethanol, isopropanol, acetone, 1,3-propanediol, propylene glycol, 0-10
0.5-at a suitable temperature of 0 ° C, preferably 10-50 ° C
The glycine derivative (6) or a salt thereof can be obtained by reacting for 100 hours and exchanging counterions with an electrodialyzer or the like if necessary. If the amount of the acid chloride (5) used is less than the above range, a large amount of the glycine derivative (4) or a salt thereof remains in the reaction product. A large amount of fatty acid is by-produced from the acid chloride (5), which is not preferable.

In this step, in order to secure the reactivity and allow a certain reaction to proceed, an alkaline substance is added to the reaction system to bring the pH in the system to the alkaline side, preferably pH 9.0 to 9.0.
It is desirable to keep it in the range of 11.0. When the pH of the reaction system is lower than this range, hydrochloric acid, which is a by-product of the reaction, forms a salt with the unreacted glycine derivative (4) and the reaction does not proceed sufficiently, while the pH is higher than this range. In this case, the decomposition of acid chloride (5) is promoted and a large amount of fatty acid is produced as a by-product. Specific examples of the alkaline substance used include inorganic bases such as sodium hydroxide, potassium hydroxide, calcium hydroxide, barium hydroxide and sodium carbonate, and organic bases such as triethylamine, pyridine and 4- (dimethylamino) pyridine. But especially sodium hydroxide,
Potassium hydroxide is practical. The amount of these alkaline substances used is an amount that maintains the system pH within the above range.

The glycine derivative (6) or a salt thereof obtained in this step can be used as it is in the next step. If necessary, a solvent such as water, methanol or ethanol may be used for recrystallization or hydrochloric acid. After treatment with a strong acid such as sulfuric acid, an acid type product of the glycine derivative (6) is obtained and recrystallized using a solvent such as acetone, hexane, petroleum ether, methanol, ethanol, butanol,
A highly purified product can be obtained by again using the appropriate neutralizing agent to prepare the glycine derivative (6) or a salt thereof.

(Step D) In this step, the cyano group of the glycine derivative (6) or its salt obtained in step C is hydrolyzed, preferably in the presence of a basic substance, to give the glycine derivative (1) or its salt. This is the step of obtaining salt. Examples of the basic substance used here include alkali metal hydroxides and alkaline earth metal hydroxides, and specific examples include sodium hydroxide, potassium hydroxide, magnesium hydroxide,
Examples thereof include calcium hydroxide and barium hydroxide.

In this step, the glycine derivative (6)
Or a salt thereof in the presence of 0.1 to 30 equivalents of a basic substance,
In an aqueous solution, if necessary, in a mixed solution of water and a polar solvent such as methanol, ethanol, isopropanol, acetone, 1,3-propanediol, and propylene glycol, 50 to 100 ° C, preferably 70 to 100 ° C. By reacting for 0.5 to 100 hours at various temperatures, and if necessary by exchanging counterions using an electrodialyzer or the like,
Glycine derivative (1) or a salt thereof can be obtained.

The glycine derivative (1) or a salt thereof obtained in this step can be used as it is in a detergent composition. If necessary, a solvent such as water, methanol or ethanol is used for recrystallization, or After treatment with a strong acid such as hydrochloric acid or sulfuric acid, an acid type product of glycine derivative (1) was obtained,
By recrystallizing it using a solvent such as acetone, hexane, petroleum ether, methanol, ethanol, butanol, and again using an appropriate neutralizing agent to give the glycine derivative (1) or its salt, a higher purity can be obtained. It can also be a purified product of

(Step E) In this step, the glycine derivative (7) or salt thereof obtained in step B is reacted with an acid chloride (5), preferably in the presence of an alkaline substance, to give a glycine derivative (1) or This is the step of obtaining the salt. The same acid chloride (5) as the raw material may be the same as in step C.

In this step, the glycine derivative (7)
Or its salt and 0.8-5.0 equivalent normally, Preferably it is 0.
9 to 1.3 equivalents of acid chloride (5) in an aqueous solution,
If necessary, in a mixed solution of water and a polar solvent such as methanol, ethanol, isopropanol, acetone, 1,3-propanediol, propylene glycol, 0-10
0.5-at a suitable temperature of 0 ° C, preferably 10-50 ° C
The glycine derivative (1) or a salt thereof can be obtained by reacting for 100 hours and exchanging the counter ion with an electrodialyzer or the like if necessary. If the amount of acid chloride (5) used is less than the above range, a large amount of the glycine derivative (7) or its salt remains in the reaction product. A large amount of fatty acid is by-produced from the acid chloride (5), which is not preferable.

In this step, in order to secure the reactivity and allow a certain reaction to proceed, an alkaline substance is added to the reaction system to bring the pH in the system to the alkaline side, preferably pH 9.0 to 9.0.
It is desirable to keep it in the range of 11.0. When the pH of the reaction system is lower than this range, hydrochloric acid, which is a by-product of the reaction, forms a salt with the unreacted glycine derivative (7) and the reaction does not proceed sufficiently, while the pH is higher than this range. In this case, the decomposition of acid chloride (5) is promoted and a large amount of fatty acid is produced as a by-product. Specific examples of the alkaline substance used here include sodium hydroxide, potassium hydroxide, calcium hydroxide, barium hydroxide, inorganic bases such as sodium carbonate,
Triethylamine, pyridine, 4- (dimethylamino)
Examples thereof include organic bases such as pyridine, but sodium hydroxide and potassium hydroxide are particularly practical. The amount of these alkaline substances used is an amount that maintains the system pH within the above range.

The glycine derivative (1) or a salt thereof obtained in this step can be used as it is in the detergent composition. It can also be a product.

The glycine derivative as the component (A) can be used alone or in combination of two or more kinds. The blending amount of the component (A) in the detergent composition of the present invention varies depending on the formulation of the detergent and the like, but is 5 to 90% by weight (hereinafter, simply indicated by%) in the entire composition. Further, in the case of a liquid, it is preferable to add 5 to 50%, particularly 10 to 40% in the whole composition, and in the case of a paste, 10% in the whole composition.
-80%, especially 15-40% is preferable, and when it is made solid, it is 40-90%, especially 70-% in the whole composition.
90% is preferable. When the content is within these ranges, foaming is more excellent and a refreshing feeling can be obtained, which is preferable.

Examples of the cationic bactericide of the component (B) used in the present invention include, for example, benzethonium salts, benzalkonium salts, pyridinium salts, dialkyldimethylammonium halides, monoalkyltrimethylammonium halides or counterions of these bactericides. Examples include cationic surfactant-based bactericides in which is converted to other anions; biguanide-based bactericides such as chlorhexidine and chlorhexidine gluconate. Of these, the following general formula (2)

[0034]

Embedded image

(In the formula, R ² represents a hydrocarbon group having 8 to 24 carbon atoms, Z has a halogen atom, an amino acid, a fatty acid, a linear or branched alkyl group or alkenyl group having 1 to 30 carbon atoms. A sulfone of a polycyclic aromatic compound having an anion residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester, or a styrene sulfonic acid having a polymerization degree of 3 or more, or having a hydrocarbon group as a substituent. A benzalkonium salt represented by the formula (indicating an anionic oligomer or polymer containing a formalin condensate) is particularly preferable because of its high bactericidal property.

In the general formula (2), the number of carbon atoms represented by R ² is 8
The hydrocarbon group having 24 to 24 is preferably a hydrocarbon group having 12 to 18 carbon atoms, particularly n-dodecyl group. Further, Z is a halogen atom such as a chlorine atom or a bromine atom, and has 8 to 8 carbon atoms.
Anion residues of phosphoric acid ester having 18 alkyl groups and the like are preferable.

As the cationic bactericide of the component (B),
Especially benzalkonium chloride, benzalkonium hexadecylphosphate, benzethonium chloride, cetylpyridinium chloride, stearyldimethylbenzylammonium chloride,
Stearyl trimethyl ammonium chloride and lauryl trimethyl ammonium chloride are preferred.

The content of the component (B) in the detergent composition of the present invention is 0.05 to 3%, preferably 0.1 to 1.5%, more preferably 0.2 to 1% in the total composition. Is preferable because it has a good bactericidal action and is not irritating by the bactericide.

In the detergent composition of the present invention, a metal chelating agent can be further added as the component (C), and the bactericidal effect of the cationic bactericide of the component (B) can be further enhanced, which is preferable. . The metal chelating agent is not particularly limited as long as it has the ability to chelate metal ions, for example, ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid,
Diethylenetriaminepentaacetic acid, nitrilotriacetic acid,
Triethylene tetramine hexaacetic acid, phosphonic acids, tripolyphosphoric acid, ethylene glycol bis (2-aminoethyl ether) tetraacetic acid, citric acid, maleic acid, polyacrylic acid, isoamylene-maleic acid copolymer, silicic acid, gluconic acid, hydroxy Benzyliminodiacetic acid,
Examples include iminodiacetic acid and salts thereof. Among these, ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, 1-hydroxyethylidene-
1,1-diphosphonic acid, citric acid, tripolyphosphoric acid or salts thereof are particularly preferred.

The amount of the component (C) in the detergent composition of the present invention is preferably 0.5 to 3 times, more preferably 0.7 to 2 times the molar amount of the component (B). It is particularly preferable because it does not reduce the bactericidal activity of the system bactericide.

In addition to the anionic and cationic surfactants, shampoos, rinses and the like may contain a metal chelating agent for the purpose of improving foaming properties and detergency at low temperatures. It is needless to say that the amount of the metal chelating agent in this case is extremely small unlike the present invention, and the effect exerted is also completely different from that of the present invention.

The cleaning composition of the present invention may optionally contain
Other surfactants such as higher fatty acid salts, alkyl sulfates, alkyl sulfonates, polyoxyethylene alkyl sulfates, alkylbenzene sulfonates, N-acyl sarcosine salts, N-acyl-N-methyl taurine salts,
Anionic surfactants such as alpha olefin sulfonates, alkyl ether acetates, polyoxyethylene alkyl ether acetates; nonionic surfactants such as polyoxyethylene alkyl ethers, sugar ester-based, sugar ether-based, sugar amide-based surfactants An amphoteric surfactant such as an imidazoline-based or betaine-based surfactant may be optionally used in combination as long as the effect of the present invention is not impaired.

Further, as other additives, components usually used in detergents, for example, humectants such as propylene glycol, sorbitol and glycerin, carboxyvinyl polymer, methyl cellulose, ethanol, polyoxyethylene glycol distearate and the like are used for viscosity adjustment. Agents, pearlizing agents, fragrances, dyes, ultraviolet absorbers, antioxidants, anti-inflammatory agents, preservatives and the like can be optionally added within a range that does not impair the effects of the present invention.

The detergent composition of the present invention can be manufactured by a conventional method. In addition, the dosage form is not particularly limited, and may be any dosage form such as liquid, paste, cream, solid, and powder. Liquid, paste, and cream are preferable, In particular, it is preferable to use a liquid. In the case of a liquid state, it is preferable to use water as a liquid medium, and the amount of water is 50% in the total composition.
Preferably it is ~ 90%. Further, the cleansing composition of the present invention is suitable as a cleansing agent for the body such as skin and hair, and is particularly preferably used for cleansing the skin.

In the detergent composition of the present invention, the pH of the aqueous solution when diluted 10 times by weight with water is preferably 4 to 8, particularly 5 to 7. In order to obtain a preferable pH, it may be adjusted by adding an acid or an alkali to the detergent composition, and an equimolar ion exchange may be performed on the component (A).

[0046]

The cleaning composition of the present invention has a low deteriorating effect on the skin, has a high detergency, is excellent in bactericidal action and its durability, and has a feeling of use from the time of cleaning to the time after cleaning. It is a good one.

[0047]

EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited to these examples.

Example 1 A detergent composition whose composition is shown in Tables 1 and 2 was produced by the following method. (Production method) A liquid detergent composition was obtained by sequentially dissolving other components in purified water.

The bactericidal effect of each of the obtained liquid detergent compositions was measured by the following method, and the feeling of use was evaluated by the following method and criteria. The results are shown in Tables 1 and 2.

(Measurement of bactericidal effect) A bactericidal test method, a diluted system agent was prepared for each of the obtained detergent compositions, and a test bacterium (Escherichia coli IFO 3) was prepared for each.
972, Pseudomonas aeruginos
a IFO 12689) was inoculated and the concentration and time for 100% sterilization were determined. That is, bacteria (about 10 ⁹ to 10 ¹⁰ cells) pre-cultured in SCD medium (manufactured by Nippon Pharmaceutical Co., Ltd.)
0.1 ml / ml), and use sterile distilled water to obtain a predetermined concentration (concentration of bactericide 1, 5, 10, 25, 50, 75, 100, 20
10 ml of the test solution diluted to 0,300,500 ppm) was inoculated and allowed to act at room temperature. Fixed time (5, 10, 1
Every 5 to 30 minutes), one platinum loop of the bacterial contact liquid was sampled, and a micro Petri dish (COR) containing 0.3 ml of SCD medium for post-culture
NING, 96-Cell Wells) was inoculated. The cells were cultured at 30 ° C. for 3 days, the growth of the bacteria was visually observed, and the strength of the effect was judged by the number of sterilized areas. That is,
It was judged by measuring the places where the bacteria did not grow on the micro planter (maximum 40). The larger the number, the stronger the sterilizing power.

(Evaluation of feeling of use) With respect to each detergent composition, each of 10 male and 10 female panelists wash their bodies, and the foaming, rinsing easiness and refreshing feeling after drying are as follows.
Sensory evaluation was performed. For evaluation, the average value was calculated according to the following criteria, and when the average value is 4.5 or more, it is very good (⊚),
The case of 3.5 to 4.4 was judged as good (◯), the case of 2.5 to 3.4 was judged as normal (Δ), and the case of 2.4 or less was judged as bad (x). (1) Foaming; 5; Good foaming. 4: Slight foaming. 3: Normal. 2: The foaming is slightly poor. 1; Foaming is poor. (2) Ease of rinsing; 5; Easy to rinse. 4; 3: Normal. 2; 1: it is difficult to rinse. (3) Refreshing feeling after drying; 5; Refreshing. 4: Slightly refreshing. 3: Normal. 2; Not very refreshing. 1; Not refreshed.

[0052]

[Table 1]

[0053]

[Table 2]

As is clear from the results shown in Tables 1 and 2, all of the products of the present invention were superior in bactericidal effect and the feeling of use from the time of skin washing to the time of washing compared with the comparative products. Moreover, these detergents were excellent in detergency and had low irritation to the skin.

Example 2 A liquid detergent composition having the following composition was prepared by the following method.

[0056]

[Table 3] (Composition) (%) (1) Lauroyl-N-carboxyethylglycine triethanolammonium 24.0 (2) Triethanolammonium laurate 4.0 (3) Lauroyl amide propyl dimethyl dimethyl carboxybetaine 2. 0 (4) Benzalkonium chloride 1.0 (5) 1-Hydroxyethylidene-1,1-diphosphonic acid 1.0 ^* (*: indicates a molar ratio to (4)) (6) Perfume 0.5 (7 ) Dibutylhydroxytoluene 0.2 (8) Ethanol 4.0 (9) Purified water Balance

(Manufacturing method) (1)-
After dissolving (3) and cooling, (4) to (8) were added to obtain a liquid detergent composition.

Example 3 A liquid detergent composition having the following composition was prepared by the following method.

[0059]

[Table 4] (Composition) (%) (1) N-cocoyl-N-carboxyethylglycine potassium 20.0 (2) N-lauroyl-N-carboxyethylglycine potassium 5.0 m (3) Potassium laurate 3.0 (4) Lauroyl amide propyl dimethyl carboxy betaine 2.0 (5) Cationized cellulose 0.2 (6) Benzalkonium hexadecylphosphate 1.0 (7) Ethylenediaminetetraacetic acid disodium 1.0 ^* ( *: Indicates the molar ratio to (6)) (8) Fragrance 0.5 (9) Dibutylhydroxytoluene 0.2 (10) Ethanol 4.0 (11) Purified water balance

(Manufacturing method) (1)-
(5) is dissolved, after cooling, (6) to (10) are added,
A liquid detergent composition was obtained.

When the body was washed with the detergent compositions obtained in Examples 2 and 3, the deodorant effect and its sustainability were excellent due to the high bactericidal power of both, and the foaming was good and easy to rinse. After drying, a refreshing feel was obtained and the usability was excellent. Further, both of the detergent compositions had low irritation to the skin and high detergency.

Claims (8)

[Claims] 1. The following components (A) and (B): (A) General formula (1) (In the formula, R ¹ represents a linear or branched alkyl group, alkenyl group or hydroxyalkyl group having 5 to 21 carbon atoms) or a glycine derivative or a salt thereof.
5 to 90% by weight, (B) cationic bactericide
A cleaning composition containing 0.05 to 3% by weight. 2. Further, (C) a metal chelating agent is added to (B)
The molar amount of the cationic bactericide is 0.5 to 3 times that of the cationic bactericide.
The cleaning composition described. 3. A cationic fungicide is represented by the general formula (2): (In the formula, R ² represents a hydrocarbon group having 8 to 24 carbon atoms, and Z 2
Is a halogen atom, an amino acid, a fatty acid, an anion residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester having a linear or branched alkyl group or alkenyl group having 1 to 30 carbon atoms or a degree of polymerization of 3 or more. Of an anionic oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound which has a styrene sulfonic acid or may have a hydrocarbon group as a substituent) The cleaning composition according to claim 1 or 2. 4. The salt of the glycine derivative represented by the general formula (1) is an alkali metal salt, a trialkanolamine salt or a basic amino acid salt.
9. The cleaning composition according to item 7. 5. In the general formula (1), R ¹ has 7 carbon atoms.
To 19 are alkyl groups or alkenyl groups.
The cleaning composition according to any one of 4 above. 6. The cleaning composition according to claim 1, wherein the pH of the aqueous solution when diluted 10 times by weight with water is 4 to 8. 7. The liquid according to any one of claims 1 to 6.
9. The cleaning composition according to item 7. 8. The cleansing composition according to claim 1, which is a personal cleansing agent.