JPH0967231A - Antimicrobial agent composition containing fatty acid silver salt and cosmetic containing the fatty acid silver salt - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prepare an antimicrobial agent composition exhibiting the antimicrobial effect in a small amount without causing the lowering in the strength of a resin, etc., and further to prepare a cosmetic safe for human bodies and high in the antimicrobial effect. SOLUTION: An antimicrobial agent composition contains a fatty acid silver salt expressed by the formula: RCOOAg (R is a linear or branched alkyl, alkenyl or alkynyl) having good dispersibility in lipophilic components, and a cosmetic contains the fatty acid silver salt. The fatty acid silver salt is known to have exhibited the antimicrobial effect in a low concentration of approximately 0.001-1.0wt.%. The effect is remarkable, when the carbon number in the fatty acid residue of the fatty acid silver salt is 7-23.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an antibacterial composition having dispersibility in lipophilic components and having an effect even in a small amount, and a cosmetic containing the fatty acid silver.

[0002]

2. Description of the Related Art Conventionally, many organic bactericides have been used as chemical agents, but organic bactericides have many drawbacks such as lack of durability and heat resistance and teratogenicity. Against this background, inorganic antibacterial agents have come to be used. The inorganic antibacterial agent is a metallic inorganic antibacterial agent in which an antibacterial metal is supported on an inorganic ion exchanger or an inorganic porous material. It has been well known that silver, copper, zinc and the like have antibacterial properties. Among them, silver is one of the few metals that has high antibacterial properties and is highly safe for the human body.

The silver-based inorganic antibacterial agent is widely used because it has higher heat resistance, does not cause volatilization and decomposition, and has higher safety than conventional organic agents. In addition, since the antibacterial effect is exhibited by silver ions, it has excellent features not found in organic drugs. For example, it has no immediate effect due to the elution of components, but has a long duration and is unlikely to produce resistant bacteria, and has a broad antibacterial spectrum such as bacteria, yeasts and fungi.

[0004]

However, the surface of the inorganic antibacterial agent particles is hydrophilic and causes poor dispersion when kneaded into a lipophilic resin. When the inorganic antibacterial agent particles are coated with wax or the like and kneaded into the resin, the dispersibility is improved, but since the metal ions are coated with the wax or the like,
The antibacterial effect is not always sufficient. For this reason, when a large amount of inorganic antibacterial agent particles are added, the resin is remarkably deteriorated.

Therefore, for example, there has been proposed a method of improving the dispersibility in a resin or the like by coating the surface of an inorganic antibacterial agent with a polyurethane resin or by binding a carboxylic acid silver salt or the like to the side chain of an acidic amino acid polymer. ing.
However, these methods have the drawback that the operation is complicated and the economy is not always good.

Therefore, the first object of the present invention is to provide an antibacterial agent composition which has dispersibility in resins and the like, is effective in a small amount, and does not cause deterioration of the strength and color tone of the resins and the like. To do. A second object is to provide a cosmetic product having the above characteristics.

[0007]

Means for Solving the Problems The present inventor has conducted extensive studies in accordance with the above object, and as a result, an antibacterial agent composition containing a fatty acid silver having lipophilicity exhibits an antibacterial effect in a small amount, and It was found that the strength of resin and the like and the deterioration of color tone are not caused. That is, the invention according to claim 1 is a fatty acid having a dispersibility in a lipophilic component, represented by the following general formula, RCOOAg (R represents a linear or branched alkyl group, an alkenyl group or an alkynyl group). An antibacterial agent composition containing silver. The fatty acid silver is lipophilic and can be dispersed in a lipophilic component without being coated with wax or the like. Furthermore, since it is not necessary to coat with wax or the like, a small amount of fatty acid silver exhibits an antibacterial effect. The inventions of claims 2 to 4 show preferred embodiments. The invention according to claim 2 is the antibacterial agent composition according to claim 1, wherein the lipophilic component is any one or more selected from fats and oils or resins. The invention according to claim 3 is the antibacterial composition according to claim 1 or 2, wherein the fatty acid residue of the fatty acid silver has a carbon number of 7 to 23. Fatty acid silver having 7 to 23 carbon atoms has greater lipophilicity and further improves dispersibility in lipophilic components. The invention according to claim 4 is the antibacterial agent composition according to any one of claims 1 to 3, wherein the content of the fatty acid silver is about 0.001 to 1.0% by weight. It is a composition. Addition of such a small amount can exert an antibacterial effect.

The present inventor has also found that cosmetics containing the fatty acid silver are safe for the human body, rich in antibacterial effect, and safe for heat, light and the like. The invention according to claim 5 is represented by the following general formula, RCOOAg (R represents a linear or branched alkyl group, an alkenyl group or an alkynyl group), and a fatty acid silver having dispersibility in a lipophilic component. It is a cosmetic containing. Cosmetics containing the antibacterial agent composition have a high antibacterial effect and are safe for the human body due to the use of silver, and are stable to heat, light, etc. and are resistant to discoloration. The product value is very high. The invention according to claim 6 is the cosmetic according to claim 5, wherein the lipophilic component is any one or more selected from fats and oils or resins. The invention according to claim 7 is the cosmetic according to claim 5 or 6, wherein the number of carbon atoms of the fatty acid residue of the fatty acid silver is
A cosmetic product having an arbitrary number of 7 to 23. 7 to 7 carbon atoms
The fatty acid silver of 23 is more lipophilic and the dispersibility in the lipophilic component is further improved. The invention according to claim 8 is the cosmetic product according to any one of claims 5 to 7, wherein
It is a cosmetic product in which the content of the fatty acid silver is approximately 0.001 to 1.0% by weight. Addition of such a small amount can exert an antibacterial effect.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION An inorganic antibacterial agent containing silver ions is highly safe and exhibits an excellent antibacterial effect.
Since the dispersibility in lipophilic components such as fats and oils and resins is poor, this improvement has been desired. Fatty acid silver, which is a silver salt of fatty acid,
In addition to having antibacterial properties comparable to inorganic antibacterial agents,
It has good dispersibility in lipophilic components such as resin, and since it is not necessary to coat it with wax or the like, or to carry it with ceramics, zeolite, etc., it is effective in a small amount,
It is also extremely easy to manufacture.

The fatty acid means a carboxylic acid RCOOH having one carboxyl group and having a chain structure. R may have a linear structure or a branched structure, and may or may not have an unsaturated bond.

Examples of such fatty acids include acetic acid, propionic acid, butyric acid, valeric acid, caproic acid, enanthic acid, caprylic acid, pelargonic acid, capric acid, undecyl acid,
Lauric acid, tridecylic acid, myristic acid, pentadecylic acid, palmitic acid, heptadecylic acid, stearic acid,
Nonadecanoic acid, arachidic acid, behenic acid, lignoceric acid, cerotic acid, heptacosanoic acid, montanic acid, melissic acid, laxeric acid, acrylic acid, crotonic acid, isocrotonic acid, undecylenic acid, oleic acid, elaidic acid,
Cetoleic acid, erucic acid, brassic acid, sorbic acid,
Examples include linoleic acid, linolenic acid, arachidonic acid, stearolic acid and the like.

Of these fatty acids, those having a fatty acid residue (that is, R in the general formula RCOOH) having 7 to 23 carbon atoms are more preferable. When the number of carbon atoms is 7 to 23, the lipophilicity of the fatty acid increases, so that the dispersibility in the lipophilic component such as fats and oils and resins becomes better. That is, for example, caprylic acid, pelargonic acid, capric acid, undecyl acid, lauric acid, tridecyl acid, myristic acid, pentadecyl acid, palmitic acid, heptadecyl acid, stearic acid, nonadecanoic acid, arachidic acid, behenic acid, lignoceric acid, undecylenic acid. , Oleic acid, elaidic acid, cetoleic acid, erucic acid, brassic acid, linoleic acid, linolenic acid, arachidonic acid, stearolic acid and the like. In producing fatty acid silver, it is desirable to prepare a sodium salt of fatty acid in advance because of its reactivity with silver ions.

As the metal having antibacterial properties, there are, for example, copper, zinc, magnesium, nickel, cobalt, etc., in addition to silver. Considering safety for human body and antibacterial effect,
Silver is the best. When producing fatty acid silver,
It is preferable to use a soluble silver nitrate solution, silver fluoride solution, silver chlorate solution, silver perchlorate solution, silver sulfate solution or the like.

Typical lipophilic components are fats and oils and resins. Examples of fats and oils are animal and vegetable fats and oils containing glycerides of fatty acids as main components, petroleum consisting of hydrocarbons, or aromatic oils consisting of alcohols, ketones, aldehydes, etc.
There are essential oils obtained from plant flowers and buds. More specifically, for example, calcium soap grease, sodium soap grease, synthetic lubricating oil grease, beef tallow, lard, coconut oil, soybean oil, cottonseed oil, rapeseed oil, seed oil, castor oil, palm oil, safflower oil, whale oil, anise. Oil, Avies oil, Ayowan oil, ylang-ylang oil, iris oil, etc. The resin includes natural resin and synthetic resin. Natural resins include, for example, balsams such as raw pine tar, Canadian balsam, true balsam, and Peruvian balsam, and buderium,
There are rubber resins such as gamboge, motu yak, and frankincense. Examples of synthetic resins include thermosetting resins such as phenol resin, urea resin, melamine resin, polyester resin, and silicone resin, and thermoplastic resins such as acrylic resin, polystyrene resin, polyethylene resin, polyvinyl chloride resin, and cellulosic resin. There is a resin. The above fatty acid silver can be used for any of these oils and fats and resins 1 or more.

The amount of the fatty acid silver added is preferably about 0.001 to 1.0% by weight with respect to the antibacterial composition. In such a range, the effect as an antibacterial agent is sufficiently exerted, the strength of the resin or the like is not deteriorated, and it is more economical. The above-mentioned preferable content of silver of fatty acid is low as compared with the content of silver required in the conventional antibacterial agent composition. This is because it is not necessary to support it with ceramics or zeolite, and it is not necessary to coat it with wax or the like. Silver-based inorganic antibacterial agents are
This is one of the causes of deterioration of resin strength and discoloration with heat. Generally, if a few% of a silver-based inorganic antibacterial agent is added to a resin, the resin strength easily deteriorates, and oxidative deterioration and yellowing deterioration occur. In many cases, blackening and deterioration were caused, and the commercial value was sometimes significantly reduced. According to the present invention, an antibacterial effect is exhibited with a low content of fatty acid silver, which is extremely advantageous in that it is not necessary to consider deterioration of the resin. There is a more preferable range of addition amount depending on the purpose of use. For example, for those that need to be kept for a relatively long time in an aqueous solution such as keeping the freshness of cut flowers,
More preferred is any amount of about 0.001-0.1% by weight. When kneading into resin, it is approximately 0.01 to 1.0.
More preferred is any amount by weight.

In the antibacterial agent composition, surfactants such as sucrose fatty acid ester and sorbitan fatty acid ester, sucrose, lactose,
It is also possible to add sugars such as maltose and starch, oils such as silicone oils and fats, fluorine oils and the like, salts such as magnesium sulfate, calcium chloride and potassium nitrate, alcohols such as ethanol, cetanol and glycerin.

Next, a method for producing the antibacterial composition of the present invention will be described. However, the manufacturing method is not limited to the following method.

First, a glyceride, that is, an ester of glycerin and a fatty acid is saponified with sodium hydroxide to prepare a solution of a sodium salt of fatty acid, that is, a soap.
It is more preferable that the solution of the soap is set to about 5% by weight. While appropriately stirring the solution of this soap,
Fatty acid silver is produced by adding about 5% by weight of silver nitrate. Stirring is, for example, a high-speed stirrer (homo mixer)
Etc. at an arbitrary rotation speed of 100 to 100,000 rpm. Generally, the higher the rotation number of stirring, the smaller the particles produced, and the better the antibacterial effect, which is preferable. Add fats and oils, surfactants, etc. as needed in any manufacturing process,
Further, if necessary, it is purified and dried to obtain an antibacterial agent composition.

Further, talc, kaolin, alumina, bentonite, acrylic fine particles and the like may be added before the formation of the fatty acid silver or after the formation of the fatty acid silver. These generally have a larger particle size than fatty acid silver (approximately 0.
It is possible to obtain an antibacterial agent composition in which fatty acid silver is homogeneously mixed. Further, it is possible to prevent the fatty acid silver from scattering from the dried antibacterial composition.

The produced antibacterial composition is excellent in dispersibility with respect to lipophilic components such as fats and oils and resins. Further, since the effect is exhibited even in a small amount, the deterioration of the strength of the resin and the deterioration due to heat, light, etc. are not caused. Furthermore, as the metal ions, copper ions, zinc ions, etc. are not used, and only silver ions are used, so that the safety is also excellent. Such an antibacterial agent composition can be applied to a wide range of fields such as medical devices, biomaterials, medical products as well as fibers and plastics.

The present invention also provides a cosmetic containing the above-mentioned fatty acid silver. Since the cosmetic contains a fatty acid silver, it has a high antibacterial effect and is safe for the human body because it does not use copper, zinc or the like as a metal ion but uses only silver. Furthermore, the product value is very high because it is stable against heat and light and is unlikely to cause discoloration. The cosmetics include basic cosmetics such as emulsion and lotion, white powder, lipstick, nail enamel, makeup cosmetics such as makeup, sunscreen products, medicated cosmetics such as deodorant cosmetics, shampoo, pomade, cold wave lotion, hair dye. It can be widely used for hair cosmetics such as, oral cosmetics, bath cosmetics such as bath salt and bath oil, and fragrances.

The fatty acid silver contained in cosmetics can be used for the above-mentioned fats and oils, any one or more lipophilic components of the resin, and the like. Further, as the fatty acid constituting the fatty acid silver contained in the cosmetics, those exemplified above can be used, and among these fatty acids, fatty acid residues having 7 to 23 carbon atoms are more preferable. Furthermore, a cosmetic containing this fatty acid silver can be produced by a conventional method, but the content of the fatty acid silver in the cosmetic is about 0.001.
It is desirable to have any amount of ˜1.0 wt%. Within this range, the antibacterial effect is sufficiently exhibited, and at the same time, the value as a cosmetic can be maintained without causing discoloration or the like.

[0023]

EXAMPLES Examples of the present invention will be described below. However, the present invention is not limited to the following examples.

<Example 1> The dispersibility of the fatty acid silver and the commercial product (control) having the formulations shown in Table 1 in diethyl sepagate was compared.

[0025]

[Table 1]

For silver stearate, silver caprylate and silver isostearate, 1% of a 5% silver nitrate aqueous solution was mixed with a high speed stirrer.
While stirring at 0000 rpm, 5% sodium stearate aqueous solution or 5% sodium caprylate aqueous solution or 5% sodium isostearate aqueous solution was gradually added, and stirring was continued for 5 minutes after the addition was completed. Manufactured by filtering, drying. In addition, the commercial product A is an inorganic antibacterial agent supported on a sodium type A-type zeolite (2.0% by weight in terms of silver ion).
In addition, the commercial product B is an inorganic antibacterial agent supported on hydrotalcite (2.0% by weight in terms of silver ion). Each sample was mixed with a high speed stirrer at 10,000 rpm for 5 minutes. After allowing them to stand at 40 ° C. for 1 week, the dispersibility of the fatty acid silver was visually judged by the presence or absence of separation. Table 2 shows the results
Shown in

[0027]

[Table 2]

(Evaluation Criteria) A: There is no separation and the dispersibility is good. ◯: Slight separation occurs, but dispersibility is almost good. X: Separated and poor in dispersibility.

Sample No. Samples Nos. 1, 2, and 3 using fatty acid silver have good or almost good dispersibility, whereas Sample No. It can be confirmed that the commercially available products of Nos. 4 and 5 have poor dispersibility and have excellent dispersibility of the fatty acid silver.

<Example 2> Sample N prepared in Example 1
o. An antibacterial resin was prepared by using Nos. 1, 4, and 5 with the formulations shown in Table 3, and the antibacterial effect, the resin strength, and the degree of resin coloring were examined.
The sample No. 12 is a control sample without the addition of fatty acid silver.

[0031]

[Table 3]

The respective components were mixed well and a 60 mm × 49 mm × 2.5 mm test piece was molded by an injection molding machine (set temperature 220 ° C.).

(Antibacterial property test) Each sample No. Each of the test pieces of 1 is placed in a sterilized flask, to which 50 ml of water collected from the river is added. 24 at 30 ℃
After shaking culture for a period of time, the number of viable bacteria before and after shaking culture was measured. The results are shown in Table 4. The sample No. The fatty acid silver concentrations of 6, 7, and 8 in water are about 0.04% by weight (silver ion concentration about 0.01% by weight), about 0.004% by weight (silver ion concentration about 0.001% by weight), It is about 0.0004% by weight (silver ion concentration about 0.0001% by weight). In addition, sample No. The silver ion concentrations in water of 9, 10, and 11 are about 0.0008% by weight, about 0.00008% by weight, and about 0.00008% by weight, respectively.

[0034]

[Table 4]

(Resin Strength Test) The strength of the resin is JIS
25 tensile test specified in K 6301-1975.
C., and the breaking strength was evaluated.

The results are shown in Table 5.

[0037]

[Table 5]

The degree of coloring of the molded test piece was visually compared with that of a control product (Sample No. 12). Table 5 shows the results.

(Evaluation of Coloring Degree) O: Light brown color, almost no difference from the control product. Δ: Brown, which is slightly colored compared to the control product, but is practical. X: Colored in black, which is not practical.

The ratio of silver ions in the fatty acid silver (27.6% by weight of silver isostearate and silver stearate and 43.0% by weight of silver caprylate) is the ratio of silver ions in commercial products A and B ( 2% by weight). Therefore, when the addition amount of the fatty acid silver and the commercial product A or B to the polypropylene resin is the same (Sample Nos. 6 and 9 and Sample N)
o. 7), 10) and 11), it is confirmed that the sample containing the fatty acid silver has a higher antibacterial effect. Regarding the deterioration of resin strength, sample No. Comparing 7 and 9 (Sample Nos. 7 and 9 have approximately the same antibacterial effect),
Sample No. 7 is much less deteriorated. Sample No. Even comparing 6 and 9 (Sample Nos. 6 and 9 have the same amount of the fatty acid silver and the commercial product A added to the polypropylene resin, and the antibacterial effect is higher in No. 6) ,
Sample No. 6 is far less deteriorated. From these results, the antibacterial effect of the antibacterial agent containing fatty acid silver and the deterioration resistance of the resin can be confirmed. Further, the antibacterial agent using fatty acid silver has a low degree of coloring despite the high content of fatty acid silver, and the anticoloring effect of the antibacterial agent containing fatty acid silver can be confirmed.

Example 3 The antibacterial composition of the present invention was used as a freshness-keeping agent for cut flowers. Freshness-keeping agents were prepared with the formulations shown in Table 6.

[0042]

[Table 6]

While stirring the purified water at 5000 rpm with a high speed stirrer, the other components were added into the purified water, heated to 80 ° C. and stirred for 3 minutes. Then use a high speed agitator 10
The mixture was cooled to 25 ° C. with stirring at 0 rpm to obtain a freshness-retaining agent. 20 vases of the same shape were prepared, 200 g of tap water was added to each, and two roses cultivated under the same environment were inserted. Of these, 10 fresh vases were added to 10 vases.
02 g was added, and the freshness of roses for 2 weeks was visually confirmed by the discoloration of flowers and the presence or absence of wilting.

No discoloration or wilting of the flower was observed even after 2 weeks in all the vases to which the freshness-retaining agent was added. On the other hand, discoloration and wilting of the flowers were observed in 4 days in all vases to which the freshness-retaining agent was not added. This makes fatty acid silver
It was confirmed that it is effective for keeping the freshness of cut flowers.

Example 4 The antibacterial composition according to the present invention was used in a cream foundation. Cream foundations were prepared with the formulations shown in Table 7. Sample N
o. No. 15 is a control product containing no antimicrobial composition.

[0046]

[Table 7]

The ingredients of phase A are weighed and gradually added to phase B while mixing with an emulsifying machine (manufactured by Mizuho Kogyo Co., Ltd.), and after the addition is completed, stirring is continued for 3 minutes to emulsify to obtain a cream foundation. This cream foundation is 3 at 25 ℃
The sample was allowed to stand for a month, and the number of general viable bacteria at the time of preparing the cream foundation and after standing for 3 months was measured. Table 8 shows the results.

[0048]

[Table 8]

From Table 8, the antibacterial effect of the antibacterial composition containing fatty acid silver was confirmed.

<Example 5> The antibacterial composition of the present invention was used in a cosmetic cream. Cosmetic creams were prepared with the formulations shown in Table 9. The sample No. 17 is a control product containing no antimicrobial composition.

[0051]

[Table 9]

Phase A is heated to 80 ° C. while stirring at 1000 rpm with a high-speed stirrer to mix and dissolve the components, then phase B heated to the same temperature is added, and stirring is continued for another 3 minutes to emulsify. . This is cooled to 25 ° C. with stirring to make a cosmetic cream. This cosmetic cream was allowed to stand at 25 ° C. for 6 months, and the number of general viable bacteria at the time of making the cosmetic cream and after standing for 6 months was measured. The results are shown in Table 10.

[0053]

[Table 10]

From Table 10, the antibacterial effect of the antibacterial composition containing fatty acid silver was confirmed.

<Example 6> The antibacterial composition of the present invention was used as an antiperspirant. The ingredients shown in Table 11 were mixed well to prepare an antiperspirant.

[0056]

[Table 11]

1 g of antiperspirant was applied to the back of the right hand, while it was not applied to the back of the left hand.
After being held for a minute, the degree of sweat generation was evaluated by sensory evaluation. The back of the right hand, to which an antiperspirant was applied, remarkably suppressed perspiration compared to the left hand.

Example 7 The antibacterial agent composition according to the present invention was used as an anti-rubbing agent. The ingredients shown in Table 12 were mixed well to prepare a floor scuff inhibitor.

[0059]

[Table 12]

5 g of a floor rub preventive agent was applied to the back, and the slippage of the skin was evaluated organoleptically. The skin on the back became smoother, and it was possible to prevent rubbing on the floor. Further, the degree of body odor generated from the back was evaluated by sensory analysis, and the generation of body odor from the back was also prevented.

<Example 8> The antibacterial composition of the present invention was used as a deodorant. Deodorants were prepared with the formulations shown in Table 13.

[0062]

[Table 13]

Raw materials other than purified water were mixed well, purified water was added while stirring at 1000 rpm with a stirrer, and the mixture was further stirred for 3 minutes to obtain a deodorant. When 5 kg of raw garbage in a 20-liter poly bucket was sprayed with 50 g of a deodorant and the deodorant effect was sensory confirmed, the smell of raw garbage was almost eliminated. Moreover, when 20 g of a deodorant was sprayed on a 5 m × 4 m room and the effect of the deodorant was sensory confirmed, the odor in the room almost disappeared.

Example 9 Dispersion of fatty acid silver in the antibacterial agent composition when talc and acrylic fine particles were added to the antibacterial agent composition, and antibacterial agent of fatty acid silver in an environment of a wind speed of 1 m / s. The state of scattering from the composition was visually confirmed.
An antibacterial agent composition was prepared with the formulations shown in Table 14.

[0065]

[Table 14]

Sample No. 21 is 14.2 g while stirring 1000 g of purified water with a high-speed stirrer at 10,000 rpm.
Sodium laurate of 10 is added and dissolved, and further 10
Add 0 g of acrylic fine particles (average particle size 1 μm),
Disperse. While further stirring this solution, 100 g of a 10% silver nitrate aqueous solution is gradually added, and stirring is continued for 10 minutes after the addition is completed. The solution was filtered and dried by a conventional method to obtain a powdery antibacterial agent composition. Sample No. 22
In addition, 99 g of talc is added and dispersed while stirring 600 g of purified water with a high-speed stirrer at 10,000 rpm. While continuing stirring, 1.57 g of silver nitrate was added, and a solution of 2.2 g of sodium isostearate dissolved in 100 g of purified water was gradually added, and stirring was continued for 10 minutes after the addition was completed. This solution was used as sample No. In the same manner as in the case of 21, the product was filtered and dried to obtain a powdery antibacterial agent composition. Sample No. In No. 23, 14.2 g of sodium laurate is added and dissolved while stirring 1100 g of purified water at 10,000 rpm with a high-speed stirrer. While further stirring this solution, 100 g of a 10% silver nitrate aqueous solution is gradually added, and stirring is continued for 10 minutes after the addition is completed. This solution was used as sample No. In the same manner as in the case of 21, the product was filtered and dried to obtain a powdery antibacterial agent composition. Sample No.
24 is 10000 rp of high-speed stirrer with 699 g of purified water
While stirring at m, 1.57 g of silver nitrate was added, and a solution of 2.2 g of sodium isostearate dissolved in 100 g of purified water was gradually added, and stirring was continued for 10 minutes after the addition was completed. This solution was used as sample No. In the same manner as in the case of 21, the product was filtered and dried to obtain a powdery antibacterial agent composition.

Sample No. No. 21 is sample No. Than 23
In addition, sample No. No. 22 is sample No. 24, the fatty acid silver was more uniformly dispersed in the powdery antibacterial agent composition, and the scattering of the fatty acid silver from the antibacterial agent composition could be further suppressed.

[0068]

INDUSTRIAL APPLICABILITY According to the present invention, an antibacterial agent composition containing a fatty acid silver having lipophilicity has dispersibility in a lipophilic component and can exert its effect even in a small amount. In particular, the greater the lipophilicity of the fatty acid residue, the greater this effect. Furthermore, since the effect can be exhibited even in a small amount, the strength of the resin does not decrease when kneaded into a resin or the like. That is, when kneading an inorganic antibacterial agent into a resin or the like, it was necessary to knead a relatively large amount of the inorganic antibacterial agent into the resin or the like because dispersibility in the resin or the like could not be ensured without coating with wax or the like. was there. Therefore, it was not possible to avoid a decrease in the strength of the resin or the like. In the present invention, the fatty acid silver is lipophilic, and it is not necessary to coat it with wax or the like. Therefore, the antibacterial effect can be exhibited even in a small amount, so that the decrease in strength of the resin or the like can be avoided. Also, by containing the fatty acid silver, it is safe for the human body and exhibits a high antibacterial effect,
Furthermore, it is possible to provide a cosmetic product having a very high commercial value because it is unlikely to cause discoloration or the like.

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Claims (8)

[Claims] 1. A fatty acid silver having a dispersibility in a lipophilic component, represented by the following general formula, RCOOAg (R represents a linear or branched alkyl group, an alkenyl group or an alkynyl group). An antimicrobial composition comprising 2. The antibacterial composition according to claim 1, wherein the lipophilic component is at least one selected from fats and oils and resins. 3. The fatty acid residue of the fatty acid silver has 7 carbon atoms.
The antibacterial agent composition according to claim 1 or 2, wherein 4. The content of the fatty acid silver is about 0.001
The antibacterial agent composition according to any one of claims 1 to 3, which is 1.0% by weight. 5. A fatty acid silver having a dispersibility in a lipophilic component, represented by the following general formula, RCOOAg (R represents a linear or branched alkyl group, an alkenyl group or an alkynyl group). Makeup cosmetics. 6. The cosmetic according to claim 5, wherein the lipophilic component is at least one selected from fats and oils and resins. 7. The fatty acid residue of the fatty acid silver has 7 carbon atoms.
The antibacterial agent composition according to claim 5 or 6, characterized in that 8. The content of the fatty acid silver is approximately 0.001 to
The antibacterial agent composition according to claim 5, wherein the antibacterial agent composition is 1.0% by weight.