JPH0967209A - Agrochemical composition and its production - Google Patents

Abstract

PROBLEM TO BE SOLVED: To easily obtain an agrochemical composition having excellent residual activity by encapsulating an agrochemical active component in a microcapsule shell composed of a combination of a yeast of natural origin with a specific polymer. SOLUTION: An agrochemical active component consisting of a noxious life controlling active component or a plant growth regulating active component is included in a microcapsule composed of a yeast cell and a polyurethane and/or polyurea resin. The inclusion is preferably carried out by the interfacial polymerization of a polyfunctional polyisocyanate monomer with a polyhydric alcohol and/or water. The agrochemical active component is e.g. insecticide, miticide, fungicide, herbicide, plant growth regulator, insect pheromone or insect growth regulator. The amount of the agrochemical active component in the composition is about 0.1-95wt.% based on the total composition. The active component compound is stably maintained in encapsulated state over a long period in the composition. The production process is extremely useful since the process enables the production of the composition having high encapsulation ratio with a simple operation.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a composition comprising a pesticidal active ingredient microencapsulated and a method for producing the same.

[0002]

2. Description of the Related Art Conventionally, in JP-A-5-124908 and the like, a composition in which a pesticide active ingredient is encapsulated in a yeast,
That is, a microencapsulated pesticide composition using yeast as a microcapsule film is known.

[0003]

However, while such a microencapsulated pesticide composition can be obtained by a relatively simple operation, there remains a problem that it is difficult to efficiently include a hydrophobic pesticide active ingredient. ing. That is, many pesticide active ingredients are hydrophobic, but since such a hydrophobic substance tends to remain outside the yeast without being incorporated into the yeast, the hydrophobic substance is incorporated into the yeast. Therefore, it is necessary to use yeast in large excess,
Otherwise, a lot of hydrophobic substances not encapsulated in yeast will be left behind. In addition, no microencapsulated pesticide composition using yeast as a microcapsule film has been practically used so far because it generally has poor residual effect.

[0004]

The present invention relates to a microencapsulated pesticide composition using yeast, which is a naturally occurring and easily available raw material, as a microcapsule film.
The pesticidal active ingredient, which is an active ingredient for controlling pests or an active ingredient for controlling plant growth, is a yeast and a polyurethane and / or
Alternatively, the invention provides an agrochemical composition (hereinafter referred to as the composition of the present invention) encapsulated in microcapsules containing a polyurea-based resin, and a simple method for producing the same.

[0005]

BEST MODE FOR CARRYING OUT THE INVENTION Examples of the agrochemical active ingredient used in the present invention include insecticides, acaricides, fungicides, herbicides, plant growth regulators, insect pheromones, insect growth regulators and the like described below. When the pesticidal active ingredient is liquid at room temperature, the pesticidal active ingredient can be used as it is, or can be used by dissolving it in a solvent. When the pesticidal active ingredient is semi-solid or solid at room temperature, it is preferable to dissolve the pesticidal active ingredient in a suitable solvent before use. Specific examples of the agrochemical active ingredient used in the present invention are shown below together with the compound numbers.

(1) α-Cyano-3-phenoxybenzyl 2- (4-chlorophenyl) -3-methylbutyrate (2) (S) -α-cyano-3-phenoxybenzyl (S) -α-2- (4-chlorophenyl) -3-methylbutyrate (3) α-cyano-3-phenoxybenzyl 2,
2,3,3-Tetramethylcyclopropanecarboxylate (4) 3-phenoxybenzyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate (5) 3-phenoxybenzyl chrysanthemate ( 6) 3-phenoxybenzyl (1R) -chrysanthemate (7) α-cyano-3-phenoxybenzyl 3-
(2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate (8) α-cyano-3- (4-chlorophenoxy) benzyl 3- (2,2-dichlorovinyl) -2,2-dimethyl Cyclopropanecarboxylate (9) α-cyano-3- (4-fluorophenoxy)
Benzyl 3- (2,2-dichlorovinyl) -2,2-
Dimethylcyclopropanecarboxylate (10) α-cyano-3-phenoxybenzyl chrysanthemate

(11) α-cyano-3-phenoxybenzyl (1R) -chrysanthemate (12) α-cyano-3- (4-chlorophenoxy)
Benzyl 2- (4-chlorophenyl) -3-methylbutyrate (13) α-cyano-3-phenoxybenzyl 2-
(4-tert-Butylphenyl) -3-methylbutyrate (14) α-cyano-3-phenoxybenzyl 2-
(3,4-Methylenedioxyphenyl) -3-methylbutyrate (15) α-cyano-4-fluoro-3-phenoxybenzyl 3- (2,2-dichlorovinyl) -2,2-
Dimethylcyclopropanecarboxylate (16) α-cyano-3-phenoxybenzyl 2-
(2-chloro-4-trifluoromethylanilino) -3
-Methyl butyrate (17) α-cyano-3-phenoxybenzyl 2-
(4-Difluoromethoxyphenyl) -3-methylbutyrate (18) α-cyano-3-phenoxybenzyl
(S) -2- (4-difluoromethoxyphenyl) -3
-Methylbutyrate (19) Cyano- (5-phenoxy-2-pyridyl)
Methyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate (20) α-cyano-3-phenoxybenzyl 2,
2-Dimethyl-3- (1,2,2,2-tetrabromoethyl) cyclopropanecarboxylate

(21) α-Cyano-3-phenoxybenzyl 1- (4-ethoxyphenyl) -2,2-dichlorocyclopropanecarboxylate (22) α-Cyano-3-phenoxybenzyl 2,
2-Dimethyl-3- (2-chloro-2-trifluoromethylvinyl) cyclopropanecarboxylate (23) 2- (4-ethoxyphenyl) -2-methylpropyl 3-phenoxybenzyl ether (24) 2- (4 -Ethoxyphenyl) -3,3,3
-Trifluoropropyl 3-phenoxybenzyl ether (25) 2-methyl-3-phenylbenzyl (1
R, trans) -2,2-Dimethyl-3- (2-chloro-2-trifluoromethylvinyl) cyclopropanecarboxylate (26) 2,3,5,6-tetrafluorobenzyl
(1R, trans) -3- (2,2-dichlorovinyl)
-2,2-Dimethylcyclopropanecarboxylate (27) 2,3,5,6-tetrafluoro-4-methylbenzyl 3- (2,2-dichlorovinyl) -2,2
-Dimethylcyclopropanecarboxylate (28) 3,4,5,6-tetrahydrophthalimidomethyl chrysanthemate (29) 3,4,5,6-tetrahydrophthalimidomethyl (1R) -chrysanthemate (30) 3-allyl -2-Methyl-4-oxocyclopent-2-enyl chrysanthemate

(31) 3-allyl-2-methyl-4-
Oxocyclopent-2-enyl (1R) -chrysanthemate (32) (S) -2-methyl-4-oxo-3- (2
-Propynyl) cyclopent-2-enyl (1R)
-Chrysanthemate (33) 1-ethynyl-2-methyl-2-pentenyl (1R) -Chrysanthemate (34) 5-benzyl-3-furylmethyl Chrysanthemate (35) 5-benzyl-3-furylmethyl (1R)
-Chrysanthemate (36) O, O-dimethyl O- (3-methyl-4-)
Nitrophenyl) phosphorothioate (37) O, O-dimethyl O- (4-cyanophenyl) phosphorothioate (38) O, O-dimethyl S- (α-ethoxycarbonylbenzyl) phosphorodithioate (39) O, O-dimethyl O- (2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothioate (40) O, O-dimethyl O- [3-methyl-4-
(Methylthio) phenyl] phosphorothioate

(41) O- (4-bromo-2,5-dichlorophenyl) O, O-diethylphosphorothioate (42) 2-methoxy-4H-1,3,2-benzodioxaphosphorine-2-sulfide ( 43) O, O-dimethyl O- (2,4,5-trichlorophenyl) phosphorothioate (44) O, O-dimethyl O- (3,5,6-trichloro-2-pyridyl) phosphorothioate (45) O, O -Dimethyl O- (4-bromo-2,
5-Dichlorophenyl) phosphorothioate (46) O- (2,4-dichlorophenyl) O-ethyl S-propyl phosphorodithioate (47) S-2,3-dihydro-5-methoxy-2-
Oxo-1,3,4-thiadiazol-3-ylmethyl O, O-dimethyl phosphorodithioate (48) dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate (49) O-ethyl O- (4- Nitrophenyl)
Phenylphosphonothioate (50) O, O-dimethyl S-methylcarbamoylmethyl phosphorothioate

(51) O, O-dimethyl S-methylcarbamoylmethyl phosphorodithioate (52) O-2-diethylamino-6-methylpyrimidin-4-yl O, O-dimethyl phosphorothioate (53) O, O- Diethyl O- (5-phenyl-3
-Isoxazole) phosphorothioate (54) O, O-diethyl O- (3-oxo-2-
Phenyl-2H-pyridazin-6-yl) phosphorothioate (55) S-2-ethylsulfinylethyl O, O
-Dimethyl phosphorothioate (56) O, O-dimethyl S- [2- (1-methylcarbamoylethylthio) ethyl] phosphorothioate (57) S- (2-ethylthioethyl) O, O-diethyl phosphorodithioate (58) ) S- (2-isopropylthioethyl) O,
O-diethyl phosphorodithioate (59) 3-diethoxyphosphorylthiomethyl-6-
Chlorobenzoxazolone (60) O, O-dimethyl S-phthalimidomethyl phosphorodithioate

(61) (E) -2-Dimethylcarbamoyl-1-methylvinyl dimethyl phosphate (62) 1,2-dibromo-2,2-dichloroethyl dimethyl phosphate (63) 2-chloro-1- (2,2) 4,5-Trichlorophenyl) vinyl dimethyl phosphate (64) 2-chloro-1- (2,4-dichlorophenyl) vinyl dimethyl phosphate (65) 2-chloro-1- (2,4-dichlorophenyl) vinyl diethyl phosphate (66) ) O, O-dipropyl O- [4- (methylthio) phenyl] phosphate (67) O- (2,4-dichlorophenyl) O-ethyl phenylphosphonothioate (68) O, O-dimethyl S- (N-methyl) -N-
Formylcarbamoylmethyl) phosphorodithioate (69) O- (2,6-dichloro-4-methylphenyl) O, O-dimethylphosphorothioate (70) 2-sec-butylphenyl methylcarbamate

(71) 2- (1-methylethyl) phenyl methylcarbamate (72) 3,4-dimethylphenyl methylcarbamate (73) 2,3-dihydro-2,2-dimethylbenzofuran-7-yl (dibutylamino) Thio) methyl carbamate (74) Isopropyl 3-chlorophenyl carbamate (75) S-Ethyl N, N-dipropyl thiol carbamate (76) 3-[(methoxycarbonyl) amino] phenyl (3-methylphenyl) carbamate (77) S- Ethyl N, N-hexamethylene thiol carbamate (78) S- (4-chlorobenzyl) N, N-diethyl thiol carbamate (79) Methyl 1- (butylcarbamoyl) benzimidazole-2-carbamate (80) Ethyl 2- ( Four Phenoxy-phenoxy)
Ethyl carbamate

(81) Ethyl N- [2,3-dihydro-2,2-dimethylbenzofuran-7-yloxycarbonyl (methyl) aminothio] -N-isopropyl-
β-alaninate (82) 1- [3,5-dichloro-4- (3-chloro-5-trifluoromethyl-2-pyridyloxy) phenyl] -3- (2,6-difluorobenzoyl) urea (83) 1- (4-chlorophenyl) -3- (2,6
-Difluorobenzoyl) urea (84) 1- (3,5-dichloro-2,4-difluorophenyl) -3- (2,6-difluorobenzoyl)
Urea (85) 1- [3,5-dichloro-4- (1,1,
2,2-Tetrafluoroethoxy) phenyl] -3-
(2,6-Difluorobenzoyl) urea (86) trans-5- (4-chlorophenyl) -N
-Cyclohexyl-4-methyl-2-oxo-3-thiazolidinecarboxamide (87) 2-tert-butyl-5- (4-tert-butylbenzylthio) -4-chloropyridazine-3 (2H)-
ON (88) 1- [4- (2-chloro-4-trifluoromethylphenoxy) -2-fluorophenyl] -3-
(2,6-Difluorobenzoyl) urea (89) tert-butyl (E) -α- (1,3-dimethyl-5-phenoxypyrazol-4-ylmethyleneaminooxy) -p-toluate (90) 3,7 , 9,13-Tetramethyl-5,11-dioxa-2,8,11-trithia-4,7,9,12-tetraazapentadeca-3,12-diene-6,10-dione

(91) 1- (6-chloropyridine-3
-Ylmethyl) -N-nitroimidazolidin-2-ylideneamine (92) 5-ethoxy-3-trichloromethyl-1,
2,4-thiadiazole (93) 3,4-dichloropropionanilide (94) N-methoxymethyl-2-chloro-2 ', 6'-
Diethylacetanilide (95) 2,6-dinitro-N, N-dipropyl-4
-Trifluoromethylaniline (96) N- (1,1,1-trimethyl-2-oxa-4-indanyl) -5-chloro-1,3-dimethylpyravir-4-carboxamide (97) 3'-iso Propoxy-2- (trifluoromethyl) benzanilide (98) diisopropyl 1,3-dithiolane-2-
Ylidene malonate (99) 1,2,5,6-tetrahydropyrrolo [3,3
2,1-i, j] quinolin-4-one (100) 3-allyloxy-1,2-benzisothiazole-1,1-dioxide

(101) 5-Methyl [1,2,4] triazolo [3,4-b] benzothiazole (102) 1,2-bis (3-methoxycarbonyl-)
2-Thioureido) benzene (103) 1- (4-chlorobenzyl) -1-cyclopentyl-3-phenylurea (104) 6- (3,5-dichloro-4-methylphenyl) -3 (2H) -pyridazinone ( 105) 3- (3,5-dichlorophenyl) -N-
Isopropyl-2,4-dioxoimidazolidin-1-
Carboxamide (106) 3- (3,5-dichlorophenyl) -5-
Methyl-5-vinyl-1,3-oxazolidine-2,4
-Dione (107) manganese ethylenebisdithiocarbamate (108) manganese and zinc ethylenebisdithiocarbamate (109) N- (trichloromethylthio) cyclohex-4-ene-1,2-dicarboximide (110) 3'-isopropoxy -2-Methylbenzanilide

(111) Tetrachloroisophthalonitrile (112) 1- (4-chlorophenoxy) -3,3-
Dimethyl-1- (1H-1,2,4-triazole-1
-Yl) butanone (113) (E) -4-chloro-2- (trifluoromethyl) -N- [1- (imidazol-1-yl) -2
-Propoxyethylidene] aniline (114) methyl N- (methoxyacetyl) -N-
(2,6-Dimethylphenyl) alaninate (115) 3-chloro-N- (3-chloro-5-trifluoromethyl-2-pyridyl) -2,6-dinitro-
4-methylaniline (116) N-butoxymethyl-2-chloro-2 ', 6'
-Diethylacetanilide (117) ethyl N-chloroacetyl-N- (2,
6-Diethylphenyl) glycinate (118) 2- [1-methyl-2- (4-phenoxyphenoxy) ethoxy] pyridine (119) (E) -1- (4-chlorophenyl)-
4,4-Dimethyl-2- (1H-1,2,4-triazol-1-yl) -1-penten-3-ol (120) 1- (4-chlorophenyl) -4,4-dimethyl-2- (1H-1,2,4-triazole-1-
Il) Pentan-3-ol

(121) 2-Bromo-N- (α, α-
Dimethylbenzyl) -3,3-dimethylbutanamide (122) 1- (1-methyl-1-phenylethyl)
-3- (p-Tolyl) urea (123) 2- (2-naphthoxy) propionanilide (124) 2- (2,4-dichloro-3-methylphenoxy) propionanilide (125) 4- (2,4- Dichlorobenzoyl)-
1,3-Dimethyl-5-pyrazolyl p-toluenesulfonate (126) 4- (2,4-dichlorobenzoyl)-
1,3-Dimethyl-5-phenacyloxypyrazole (127) 4- (2,4-dichloro-3-methylbenzoyl) -1,3-dimethyl-5- (4-methylphenacyloxy) pyrazole (128) 2,4,6-Trichlorophenyl 4-nitrophenyl ether (129) 2,4-Dichlorophenyl 3-methoxy-4-nitrophenyl ether (130) 2,4-Dichlorophenyl 3-methoxycarbonyl-4-nitrophenyl ether

(131) 2-benzothiazole-2-
Iloxy-N-methylacetanilide (132) 2 ', 3'-dichloro-4- (ethoxymethoxy) benzanilide (133) 5-tert-butyl-3- (2,4-dichloro-5-isopropoxyphenyl) -1 , 3,4-Oxadiazol-2 (3H) -one (134) 2-amino-3-chloro-1,4-naphthoquinone (135) Methyl 2- [3- (4,6-dimethoxypyrimidine-2- (Il) ureidosulfonyl] benzoate (136) ethyl 5- [3- (4,6-dimethoxypyrimidin-2-yl) ureidosulfonyl] -1-methylpyrazole-4-carboxylate (137) O- (4-tert- Butylphenyl) N-
(6-Methoxy-2-pyridyl) -N-methylthiocarbamate (138) O- (3-tert-butylphenyl) N-
(6-Methoxy-2-pyridyl) -N-methylthiocarbamate (139) O- (4-chloro-3-ethylphenyl)
N- (6-methoxy-2-pyridyl) -N-methylthiocarbamate (140) O- (4-bromo-3-ethylphenyl)
N- (6-methoxy-2-pyridyl) -N-methylthiocarbamate

(141) O- (3-tert-butyl-4)
-Chlorophenyl) N- (6-methoxy-2-pyridyl) -N-methylthiocarbamate (142) O- (4-trifluoromethylphenyl)
N- (6-methoxy-2-pyridyl) -N-methylthiocarbamate (143) 1- (2-chlorobenzyl) -3- (α,
α-Dimethylbenzyl) urea (144) N- (3,5-dichlorophenyl) -1,
2-Dimethylcyclopropane-1,2-dicarboximide (145) Isopropyl 3,4-diethoxyphenylcarbamate (146) N- [4-chloro-2-fluoro-5-
(Pentyloxycarbonylmethoxy) phenyl]-
3,4,5,6-Tetrahydrophthalimide (147) 7-Fluoro-6- (3,4,5,6-tetrahydrophthalimide) -4- (2-propynyl)-
1,4-benzoxazin-3 (2H) -one (148) 2 ', 6'-dimethyl-N- (3-methoxy-
2-Tenyl) -2-chloroacetanilide (149) 1- [2-chloroimidazo [1,2-a]
Pyridin-3-ylsulfonyl] -3- (4,6-dimethoxypyrimidin-2-yl) urea (150) 3-isopropyl-1H-2,1,3-benzothiadiazin-4 (3H) -one- 2,2-dioxide

(151) 2- (1-Ethoxyiminobutyl) -5- [2- (ethylthio) propyl] -3-hydroxycyclohex-2-en-1-one (152) 2 ', 6'-diethyl -N- (2-propoxyethyl) -2-chloroacetanilide (153) S- (1-methyl-1-phenylethyl)
Piperidine-1-carbothioate (154) S-benzyl N-ethyl-N- (1,2
-Dimethylpropyl) thiol carbamate (155) 2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine (156) 2-methylthio-4,6-bis (ethylamino) -1,3 , 5-Triazine (157) 2-chloro-4,6-bis (ethylamino) -1,3,5-triazine (158) 2-methylthio-4-ethylamino-6-
(1,2-Dimethylpropylamino) -1,3,5-triazine (159) 3- [2- (3,5-dimethyl-2-oxocyclohexyl) -2-hydroxyethyl] glutarimide (160) Isopropyl ( 2E, 4E) -11-Methoxy-3,7,11-trimethyl-2,4-dodecadienoate

(161) 2-tert-butylimino-3
-Isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazin-4-one (162) 2-phenoxy-6- (neopentyloxymethyl) pyridine (163) 3 -Chloro-2- [7-fluoro-4-
(2-propynyl) -3,4-dihydro-1,4-benzoxazin-3 (2H) -one-6-yl] -4,
5,6,7-Tetrahydro-2H-indazole (164) 4'-chloro-2 '-(α-hydroxybenzyl) isonicotinic acid anilide (165) 6- (benzylamino) purine (166) 3- (4- Chlorophenyl) -1,1-dimethylurea (167) 3- (3,4-dichlorophenyl) -1,
1-Dimethylurea (168) 2,4-dinitro-6-sec-butylphenol (169) 2,4-Dimethyl-5- (trifluoromethylsulfonylamino) acetanilide (170) 6- (furfurylamino) purine

(171) 1-phenyl-3- [4-
(2-Chloropyridyl)] urea (172) S, S-dimethyl 2- (difluoromethyl) -4- (2-methylpropyl) -6- (trifluoromethyl) pyridine-3,5-dicarbothioate ( 173) 3- (4,6-dimethoxy-1,3,5-
Triazin-2-yl) -1- [2- (2-methoxyethoxy) phenylsulfonyl] urea (174) exo-1-methyl-4- (1-methylethyl) -2- (2-methylphenylmethoxy)- 7-Oxabicyclo [2.2.1] heptane (175) 2,6-diethyl-N-[(2-cis-butenoxy) methyl] -2-chloroacetanilide Of the agrochemical active ingredients contained in the composition of the present invention. The content of the pesticidal active ingredient may vary depending on the type and application, but is usually 0.1 to 95% by weight, preferably 1 to 60% by weight based on the total weight of the composition of the present invention. The pesticidal active ingredient may also be a mixture of two or more pesticidal active ingredients.

The polyurethane and polyurea resins used in the composition of the present invention can be produced by interfacial polymerization. In the case of polyurethane resins, polyurea resins are usually prepared by reacting a polyfunctional polyisocyanate monomer with a polyhydric alcohol. In the case of a resin, it is usually produced by reacting a polyfunctional polyisocyanate monomer with water. Examples of the polyfunctional polyisocyanate monomer used include, for example, toluene diisocyanate, hexamethylene diisocyanate, diphenylmethane diisocyanate, naphthyl diisocyanate, cyclohexyl diisocyanate, triphenyl diisocyanate, triisocyanate, an adduct of toluene diisocyanate and trimethylolpropane, hexamethylene. Self-condensates of diisocyanates and the like are mentioned, and specific examples of trade names of easily available products include Sumijour L (manufactured by Sumitomo Bayer Urethane Co., Ltd.), Sumijour N (manufactured by Sumitomo Bayer Urethane Co., Ltd.), Sumijour HT ( Sumitomo Bayer Urethane Co., Ltd., Death Module Z (Sumitomo Bayer Urethane Co., Ltd.) and the like.

Examples of the polyhydric alcohol used include ethylene glycol, propylene glycol, butylene glycol, hexanediol, heptanediol, dipropylene glycol, glycerin, resorcin, hydroquinone and the like. The amount of the polyfunctional polyisocyanate monomer used varies depending on the type of the isocyanate monomer used and the like, but is usually 0.001 to 40% by weight, preferably 0.005 to 20% by weight based on the total weight of the composition of the present invention. % By weight. Further, it is usually 1 to 200 parts by weight, preferably 1 to 50 parts by weight, relative to 100 parts by weight of the agricultural chemical active ingredient. The amount of polyhydric alcohol used varies depending on the type of alcohol used and the like, but is usually 0.001 relative to the total weight of the composition of the present invention.
-30% by weight, preferably 0.005-15.0% by weight
It is.

Specific examples of the yeast used in the present invention include Saccharomyces cereviceae of the genus Saccharomyces, Saccharomyces rouxii, and Saccharomyces carlsberge.
nsis], Saccharomyces uvarum [Saccharomycesuva
rum], Endomyces vernalis of the genus Endomyces, Lipomyces lipofer of the genus Lipomyces, Lypomyces atarkeyi, and Tricosporon pullulans of the genus Trichosporone
], Candi Doutilus [Candi
da utills], Candida tropis
picallis], Candida lyp
olytica], Candida flaveri
] Etc. can be mentioned.

Any yeast may be used in the composition of the present invention, and the yeast may be alive or dead.
Of course, a yeast strain in which the components inside the dead yeast strain are leached may be used, or a yeast strain treated with a chemical such as an acid, an alkali or an enzyme may be used. There are various types of yeast such as oval, spherical, lens-shaped, columnar, and elliptical shapes depending on the type of yeast, and spherical, elliptical, and oval shapes are preferred. The particle size of the yeast used in the composition of the present invention may vary depending on the type of yeast used, but is usually 3 to 20 μm. Further, these yeasts may be used as a mixture of two or more kinds at an arbitrary ratio. The amount of yeast added to the composition of the present invention may vary depending on the type of yeast, the type and content of the agrochemical active ingredient, but is usually 0.001 relative to the total weight of the composition of the present invention.
˜90% by weight, preferably 0.01 to 60% by weight. In addition, 1 is usually added to 100 parts by weight of the pesticide active ingredient.
To 900 parts by weight, preferably 10 to 300 parts by weight.

The composition of the present invention can be in the form of powder, granules, wettable powder, wettable granules, suspension in water, liquid and the like. To make the composition of the present invention into powder, granules, hydratable powder or hydratable granules, if necessary, a solvent, a dispersant, a binder, a surfactant, a carrier, a stabilizer, a perfume, a pigment. Etc. are added. Further, in order to make the composition of the present invention a suspension or liquid in water, if necessary, a solvent, a dispersant, a surfactant, a thickener, an antifreezing agent, water, an antiseptic, a stabilizer, and a fragrance. , Dyes, etc. are added.

As the solvent used in the present invention,
For example, saturated aliphatic hydrocarbons such as decane, tridecane, tetradecane, hexadecane, octadecane, etc., unsaturated aliphatic hydrocarbons such as 1-undecene, 1-heneicosene, halogenated carbonization such as SELECROLL S45 (solvent manufactured by Zeneca), etc. Hydrogen, ketones such as methyl ethyl ketone and cyclohexanone, alcohols such as ethanol, butanol and octanol, ethyl acetate, dimethyl phthalate,
Esters such as methyl laurate, ethyl palmitate, octyl acetate, dioctyl succinate, didecyl adipate, xylene, ethylbenzene, octadecylbenzene, Solvesso 100 (exxon chemical solvent), Hisol SAS-296 (solvent by Nippon Petrochemical) Alkylbenzenes such as dodecylnaphthalene, tridecylnaphthalene, Solvesso 200 (solvent manufactured by Exxon Chemicals), etc., ethylene glycol, diethylene glycol, propylene glycol monomethyl ether, glycols such as 2-ethoxyethanol, glycol esters, glycols Ethers, oleic acid,
Fatty acids such as capric acid and enanthate, polyglycols such as tetraethylene glycol, polyethylene glycol and polypropylene glycol, acid amides such as N, N-dimethylformamide and diethylformamide, olive oil, soybean oil, rapeseed oil, castor oil , Linseed oil, cottonseed oil, palm oil, avocado oil, shark liver oil and other animal and vegetable oils, machine oil and other mineral oils, glycerin, and glycerin derivatives such as glycerin fatty acid ester. In addition, these solvents can be used alone or as a mixture of two or more kinds of solvents at an arbitrary ratio, and the addition amount thereof is usually 20 to 500 parts by weight with respect to 100 parts by weight of the agrochemical active ingredient.

Examples of the dispersant used in the present invention include natural polysaccharides such as gelatin, gum arabic and sodium alginate, semi-synthetic polysaccharides such as sodium carboxymethyl cellulose salt and lignin sulfonate,
Synthetic water-soluble polymers such as polyvinyl alcohol and polyvinylpyrrolidone, mineral substances such as magnesium aluminum silicate, alkylbenzene sulfonates, alkyl phosphates, formalin condensates of naphthalene sulfonates, higher alkyl sulfonates, higher alkyl quaternary Surfactants such as higher ammonium salts, higher fatty acids or salts thereof, and higher alkylcarboxylic acid salts can be used. Among these dispersants, it is preferable to use gum arabic or polyvinyl alcohol, for example, Gohsenol GL-05 (polyvinyl alcohol manufactured by Nippon Synthetic Chemical Industry, polymerization degree 1000 or less, saponification degree 86.5-89 mol%), Gohsenol KL-05. (Polyvinyl alcohol manufactured by Nippon Synthetic Chemical Industry, polymerization degree 1000 or less, saponification degree 7
Commercially available products such as 8.5 to 81.5 mol%) are used. These dispersants may be used alone, or two or more kinds may be mixed at an arbitrary ratio. The addition amount of the dispersant in the composition of the present invention may vary depending on the type of the dispersant and the type and content of the agrochemical active ingredient, but is usually 0.5 to 20 relative to the total weight of the composition of the present invention. %, Preferably 2 to 10% by weight.

Examples of the binder used in the composition of the present invention include inorganic binders, natural organic binders, semi-synthetic binders, synthetic resin binders and waxes. Examples of the inorganic binder include bentonite, montmorillonite, water glass, colloidal silica and the like. Examples of the natural organic binder include starch, dextrin, casein, gelatin, glue, agar, gum arabic, corn starch, natural rubber, pulp liquid and the like. As the semi-synthetic binder, carboxymethyl cellulose, carboxymethyl cellulose sodium salt, hydroxypropyl methyl cellulose, nitrocellulose, cellulose acetate, methyl cellulose,
Examples thereof include cellulose-based binders such as ethyl cellulose and hydroxypropyl cellulose, and lignin-based binders such as lignin, sodium lignin sulfonate, and ammonium lignin sulfonate. Synthetic resin binders include high density polyethylene, low density polyethylene, polyolefins such as polypropylene, halogenated polyolefins such as polychloroethylene and polypropylene chloride, acrylic polymers such as polyacrylonitrile and polymethylmethacrylate, polystyrene, acrylonitrile. -Polystyrene-butadiene copolymer, polyvinyl chloride, polyvinyl acetate, vinyl chloride-vinyl acetate copolymer, vinyl-based polymers such as chlorinated vinyl chloride, polyvinyl ether, polyvinylidene chloride, ketone-formalin resin, phenoxy resin Synthetic rubber such as polybutadiene, polyisobutylene and polyisoprene, silicone resin, fluororesin such as polyvinylidene fluoride and polytrifluoroethylene, acetal tree such as polyacetal Polyester such as nylon 6, nylon 66, polyethylene terephthalate, olefin oxides such as polyamide, polyimide, polyethylene oxide and polyphenylene oxide, carbonate resin such as polycarbonate, polysulfone resin, polyurethane, polyurethane such as polyurethane urea, epoxy resin, phenol Resin, melamine resin, maleic acid resin, urea resin, polyvinylpyrrolidone, etc. are mentioned. Examples of the wax include natural wax, petroleum wax, synthetic wax and the like. Examples of natural waxes include candelilla wax, carnauba wax, rice wax, wood wax, jojoba oil, beeswax, lanolin, whale wax,
Examples include beef tallow, ozokerite, and ceresin. Examples of the petroleum wax include paraffin wax and microcrystalline wax. Examples of synthetic waxes include montan wax, polyethylene wax, Fischer-Tropsch wax, sazol wax, hydrogenated castor oil, 12-hydroxystearic acid, stearic acid, stearyl alcohol, lauron,
Stearone, isopropyl myristate, glycerin fatty acid ester, glycol fatty acid ester, sorbitan fatty acid ester and the like can be mentioned.

When the binder used in the composition of the present invention is water-soluble, it may be dissolved in water and added as an aqueous solution, may be added as a powder, or may be melted by heating. It may be used as a substance or as an emulsion in which these fine particles are dispersed in water. When the binder is insoluble in water, it is preferably added as an emulsion dispersed in water, used as a melt melted by heating, or used as an emulsion in which these fine particles are dispersed in water. Two or more kinds of binders may be mixed and used at an arbitrary ratio. The amount of the binder added may vary depending on the kind of the binder, but is usually 0.1 to 40% by weight, preferably 0.5 to 30% by weight, based on the total weight of the composition of the present invention.

Examples of the surfactant used in the composition of the present invention include polyoxyethylene alkyl ether, polyoxyethylene alkyl allyl ether, polyoxyethylene lanolin alcohol, polyoxyethylene alkylphenol formalin condensate, polyoxyethylene sorbitan fatty acid ester. , Polyoxyethylene glyceryl monofatty acid ester, polyoxypropylene glycol monofatty acid ester, polyoxyethylene sorbitol fatty acid ester, polyoxyethylene castor oil derivative, polyoxyethylene fatty acid ester, higher fatty acid glycerin ester, sorbitan fatty acid ester,
Sucrose fatty acid ester, polyoxyethylene polyoxypropylene block polymer, polyoxyethylene fatty acid amide, alkylolamide, nonionic surfactant such as polyoxyethylene alkylamine, alkylamine hydrochloride such as dodecylamine hydrochloride, alkyl tetrachloride Alkyl quaternary ammonium salts such as primary ammonium salts and dodecylalkyl trimethyl ammonium salts, alkyl dimethyl benzyl ammonium salts, alkyl pyridinium salts, alkyl isoquinolinium salts, dialkyl morpholinium salts, benzethonium chloride, polyalkyl vinyl pyridinium salts, etc. Cationic surfactants, sodium fatty acid such as sodium palmitate, ether carboxylic acids such as sodium polyoxyethylene lauryl ether carboxylate Amino acid condensates of higher fatty acids such as thorium, sodium lauroyl sarcosine and sodium N-lauroyl glutamate, higher alkyl sulfonates such as sodium dodecylbenzene sulfonate, higher fatty acid ester sulfonates such as laurate ester sulfonate, dioctyl sulfo. Dialkyl sulfosuccinic acid such as succinate, higher fatty acid amide sulfonic acid such as oleic acid amide sulfonate, dodecylbenzene sulfonate, alkyl allyl sulfonate such as diisopropylnaphthalene sulfonate, formalin condensate of alkyl allyl sulfonate Higher alcohol sulfate ester salts such as pentadecane-2-sulfate, polyoxyethylene alkyl ether sulfate ester salts such as sodium polyoxyethylene dodecyl ether sulfate Salts, polyoxyethylene alkyl phosphates such as dipolyoxyethylene dodecyl ether phosphate, anionic surfactants such as styrene-maleic acid copolymer, alkyl vinyl ether-maleic acid copolymer, N-lauryl alanine, N, N, N-trimethylaminopropionic acid,
N, N, N-trihydroxyethylaminopropionic acid, N-hexyl N, N-dimethylaminoacetic acid, 1-
Examples include amphoteric surfactants such as (2-carboxyethyl) pyridinium betaine and lecithin. Two or more kinds of these surfactants may be mixed and used, and the amount thereof is 0.1 to 10% by weight based on the total weight of the composition of the present invention.

The carrier used in the composition of the present invention includes, for example, mineral carrier, white carbon, animal and plant carrier. As the mineral substance carrier, kaolinite such as kaolinite, dickite, nacrite, and halosite, chrysotile, lizzite, anticolite, serpentine such as amethite, calcium montmorillonite, magnesium montmorillonite, saponite, hectorite, sauconite, and hyderite Such as smectite, piophyllite, talc, wax, muscovite, fengite, mica such as sericite and illite, silica such as cristobalite and quartz, hydrous magnesium silicate such as attapulgite and sepiolite, calcium carbonate such as dolomite, and gypsum. , Sulfate minerals such as gypsum, zeolite, zeolite, tuff, vermiculite, laponite, pumice, diatomaceous earth, clay, acid clay, activated clay, diatomaceous earth, mudstone, ammonium sulfate, urea, ammonium chloride, etc. It is. Examples of the white carbon include wet method silica, dry method silica, and a calcined product of wet method silica. Examples of animal and plant carriers include wheat flour, sucrose, dextrin, wood flour, starch, bran, bran, chaff, soybean flour, carnauba wax, fats and oils. These carriers may be used alone, or two or more kinds may be mixed and used at an arbitrary ratio. The addition amount of the carrier in the composition of the present invention may vary depending on the kind of the carrier, but is usually in the range of 0.1 to 99% by weight.

Examples of the stabilizer used in the composition of the present invention include antioxidants, light stabilizers, ultraviolet absorbers, quenchers, radical scavengers, and peroxide decomposers. Examples of the antioxidants include phenolic antioxidants, amine antioxidants, phosphorus antioxidants, sulfur antioxidants and the like. Examples of the UV absorber include benzotriazole-based UV absorbers, benzophenone-based UV absorbers, benzoate-based UV absorbers, cyanoacrylate-based UV absorbers, salicylic acid-based UV absorbers, hindered amine-based UV absorbers, and the like. Examples of the quencher include organic nickel compounds. Further, stabilizers such as isopropyl acid phosphate, liquid paraffin, epoxidized soybean oil, epoxidized linseed oil, and epoxidized vegetable oil such as epoxidized rapeseed oil can also be used. Further, these stabilizers may be used as a mixture of two or more kinds in an arbitrary ratio. Although the amount of the stabilizer added may vary depending on the kind thereof, it is usually 0.01 to 0.01% based on the total weight of the composition of the present invention.
5% by weight.

Examples of the thickener used in the composition of the present invention include natural polysaccharides such as xanthan gum and locust bean gum, magnesium aluminum silicate,
Examples thereof include mineral substances such as bentonite, semi-synthetic polysaccharides such as carboxymethyl cellulose sodium salt, and synthetic water-soluble polymers such as polyacrylates. When used, two or more kinds of them may be mixed and used. The amount of thickener added is
Although it may vary depending on the type of the thickener, it is usually 0.01 to 10% by weight based on the total weight of the composition of the present invention.

Examples of the antifreezing agent used in the composition of the present invention include propylene glycol, ethylene glycol and diethylene glycol. The addition amount of the antifreezing agent may vary depending on the kind thereof, but is usually 0.1 to 20% by weight based on the total weight of the composition of the present invention. Examples of the preservative used in the composition of the present invention include formalin, Proxel GXL (manufactured by Zeneca), Neoplatinus (manufactured by Ueno Pharmaceutical Co., Ltd.) and the like.
The addition amount of the preservative may vary depending on the kind of the preservative, but it is usually 0.1 to 5% by weight based on the total weight of the composition of the present invention. In addition to this, the composition of the present invention also contains rhodamine B,
Rhodamines such as solar rhodamine, colorants such as yellow dye 4, blue dye 1, red dye 2 and tar dyes, ethyl acetoacetate, methyl anthranilate, isoamyl isovalerate, ethyl enanthate, ethyl cinnamate, isoamyl butyrate. Ester such as, caproic acid, organic acid such as cinnamic acid, cinnamic alcohol, geraniol, citral,
Alcohols such as decyl alcohol, vanillin, piperonal, aldehydes such as perilaldehyde, mannitol, ketones such as methyl β-naphthyl ketone, and fragrances such as menthol may be added. Each is usually 0.01 to 5% by weight relative to the total weight of the composition of the present invention.

Next, the method for producing the composition of the present invention will be described in detail. The composition of the present invention is produced by the interfacial polymerization of a polyfunctional polyisocyanate monomer and a polyhydric alcohol and / or water when the pesticidal active ingredient is included in the yeast cell, and the pesticidal active ingredient is added to the yeast. It is manufactured by two steps, that is, the step of encapsulating and the step of encapsulating the agricultural chemical active ingredient in polyurethane or polyurea resin by interfacial polymerization reaction. These steps can be performed separately or simultaneously, and a typical method thereof will be shown below.

A dispersant and water and / or a polyhydric alcohol are mixed to prepare an aqueous solution containing the dispersant. Next, the agrochemical active ingredient, the polyfunctional polyisocyanate monomer, the yeast, and the solvent, if necessary, are mixed to prepare an oil phase containing them. Then, the oil phase containing the agricultural chemical active ingredient, the polyfunctional polyisocyanate monomer, the yeast and the like is added to the aqueous dispersant solution and peptized by a peptizer. Examples of the peptizer used at this time include a high-speed rotating high-shear stirring aggregator, a dissolver, a colloid mill, a homogenizer, an ultrasonic peptizer, and the like. K. Auto homomixer (made by Tokushu Kika Kogyo),
T. K. Homomic Line Flow (made by Tokushu Kika Kogyo),
Ultra Homo mixer (manufactured by Nippon Seiki Seisakusho), NNK colloid mill (manufactured by Nippon Seiki Seisakusho) and the like can be mentioned. The rotation speed during peptization may vary depending on the type and structure of the peptizer and the type of liquid to be peptized, but is usually 500 to 10,000 rp.
m, preferably 2000 to 8000 rpm, and the temperature during peptization is usually 5 to 50 ° C. Also, the peptization time is
It may vary depending on the type and structure of the peptizer and the type of liquid to be peptized, but is usually 0.01 to 0.3 hours, preferably 0.0
It is 2 to 0.15 hours. The size of the deflocculated oil droplet particles is about 0.1 depending on the deflocculating strength and the amount of the dispersant added.
It can be adjusted within the range of up to 200 μm, but 0.1 to
It is preferably adjusted to 50 μm. In the peptized solution thus obtained, the agricultural chemical active ingredient is then encapsulated in the polyurethane or polyurea resin by interfacial polymerization. The reaction time of the interfacial polymerization varies depending on the kind and addition amount of the monomer, the reaction temperature and the like, but is usually 1 to 48 hours, and the reaction temperature is usually 40 to 80 ° C, preferably 50 to 70 ° C. The stirring conditions at the time of reaction are 10 to 200 rpm,
The speed is preferably 50 to 150 rpm, and as a stirrer that is usually used, a stirrer such as a chemical mixer or a three-one motor (a stirrer manufactured by Shinto Kagaku Co., Ltd.) can be mentioned.

When the microencapsulated product thus obtained is prepared as a solid preparation, it is dried and solidified by freeze-drying, spray-drying, reduced-pressure drying or the like, and if necessary, a solvent or a dispersant is used. , Binders, surfactants, carriers, stabilizers, fragrances, dyes, etc. are added. When the microencapsulated product is prepared as a liquid preparation, the microencapsulated product, if necessary, a solvent, a dispersant, a surfactant, a thickener, an antifreezing agent, water, a preservative,
Stabilizers, fragrances, pigments, etc. are added.

The composition of the present invention can also be produced by the following method. A dispersant and water and / or a polyhydric alcohol are mixed to prepare an aqueous solution containing the dispersant. Next, an agricultural chemical active ingredient, a polyfunctional polyisocyanate monomer, and a solvent, if necessary, are mixed to prepare an oil phase containing them. Then, an oil phase containing an agricultural chemical active ingredient, a polyfunctional polyisocyanate monomer, etc. is added to an aqueous dispersant solution and peptized by a peptizer. Examples of the peptizer used at this time include a high-speed rotating high-shear stirring aggregator, a dissolver, a colloid mill, a homogenizer, an ultrasonic peptizer, and the like. K.
Auto Homo Mixer, T. K. Homomic line flow, ultra homomixer, NNK colloid mill and the like can be mentioned. The number of revolutions at the time of peptization depends on the type and structure of the peptizer,
It varies depending on the type of peptized liquid, but usually 500 to 10
000 rpm, preferably 2000 to 8000 rpm, and the temperature during peptization is usually 5 to 50 ° C. The deflocculation time may vary depending on the type and structure of the deflocculator and the type of the peptized liquid, but is usually 0.01 to 0.3 hours, preferably 0.02 to 0.15 hours. The size of the peptized oil droplet particles depends on the peptization strength and the amount of the dispersant added.
It can be adjusted within the range of about 0.1 to 200 μm,
It is preferably adjusted to 0.1 to 50 μm. A dispersion prepared by mixing yeast in water is added to the peptized solution thus obtained, and these are mixed. The mixing time at this time is usually 1 to 48 hours, and the mixing temperature is usually 40 to 80 ° C, preferably 50 to 70 ° C. Also,
The stirring conditions at the time of mixing are 10 to 200 rpm, preferably 50 to 150 rpm, and examples of commonly used agitators include chemical mixers and three-one motors.

Further, the composition of the present invention can be produced by the following method. A dispersant and water are mixed to prepare an aqueous solution containing the dispersant. Next, an agricultural chemical active ingredient, a polyfunctional polyisocyanate monomer, and a solvent, if necessary, are mixed to prepare an oil phase containing them. Then, an oil phase containing an agricultural chemical active ingredient, a polyfunctional polyisocyanate monomer, etc. is added to an aqueous dispersant solution and peptized by a peptizer. Examples of the peptizer used at this time include a high-speed rotating high-shear stirring agitator peptizer, a dissolver, a colloid mill, a homogenizer, and an ultrasonic peptizer.
More specifically, T.W. K. Auto Homo Mixer, T.
K. Homomic Line Flow, Ultra Homo Mixer,
Examples include NNK colloid mill. The number of revolutions during peptization varies depending on the type and structure of the peptizer and the type of liquid to be peptized, but is usually 500 to 10,000 rpm, preferably 2
000-8000 rpm, and the temperature during peptization is usually 5
５０50 ° C. In addition, the peptization time may vary depending on the type and structure of the peptizer and the type of peptized liquid, but is usually 0.0
It is 1 to 0.3 hours, preferably 0.02 to 0.15 hours. In addition, the size of the peptized oil droplet particles is the peptization strength,
It can be adjusted within a range of about 0.1 to 200 μm depending on the amount of the dispersant added, but it is preferably adjusted to 0.1 to 50 μm. To the peptized solution thus obtained, a suspension in water containing yeast, polyhydric alcohol and, if necessary, a solvent and the like is added and mixed. The mixing time at this time is usually 1 to 48.
Time, and the mixing temperature is usually 40 to 80 ° C, preferably 50 to 70 ° C. In addition, the stirring condition during mixing is 10 to 200 rpm, preferably 50 to 150 rpm.
Examples of the commonly used stirrer include chemical mixers and three-one motors.

In order to efficiently incorporate the pesticidal active ingredient into the yeast cells, it is preferable to elute the intracellular ingredients in advance. For example, ethanol was added to the yeast dispersion, and the components inside the cells were eluted by stirring to remove the components eluted by centrifugation, followed by the treatment as described above. It is preferred to produce the composition of the present invention.

The composition of the present invention is a mixed composition of a yeast containing an agrochemical active ingredient and a polyurethane and / or polyurea resin microspheres containing an agrochemical active ingredient, and an agrochemical active ingredient. A composition comprising a yeast and a microsphere of a polyurethane and / or a polyurea resin encapsulated therein, and a composition comprising a microsphere of a polyurethane and / or a polyurea resin including an agrochemical active ingredient encapsulated in the yeast. The composition may be in any form of a composition in which the microbe and the agrochemical active ingredient are encapsulated in microspheres made of a mixture of yeast and polyurethane and / or polyurea resin. Further, the mixing ratio of the microspheres of polyurethane and / or polyurea resin and the microspheres of yeast in the composition of the present invention can be arbitrarily selected according to the application scene.

The composition of the present invention is usually used as follows. For example, when the composition of the present invention is in the form of powder or granules, it is applied in the same manner as dusts or granules. When it is in the form of hydratable powder or hydratable granules, it is diluted with water to an appropriate ratio and then sprayed in the same manner as a usual wettable powder. When the composition of the present invention is in the form of suspension or liquid in water, it is applied in the same manner as a usual suspension or solution in water. When spraying the composition of the present invention, it can be sprayed using an appropriate device. Examples of the spraying device include a pipe duster, a granulator, and a hydraulic sprayer. Further, the composition of the present invention may be sprayed from the ground, or may be sprayed in the air by a helicopter or an aircraft.

The amount of the composition of the present invention applied varies depending on the type of active ingredient of the composition of the present invention, weather conditions, formulation form, treatment time, method, place, target, etc. In general, the amount of the active ingredient is an insecticide. , 1 for acaricides and nematicides
0.01 to 1000 g per m ² , preferably 0.01
~ 100 g, usually 1 m ² for insect growth regulators
The amount is 0.001 to 1 g. In the case of a fungicide, it is usually from 1 g to 10 kg per ha, in the case of a herbicide, it is usually from 1 g to 10 kg per ha, and in the case of a plant preparation control agent, it is usually from 0.001 g to 10 g per ha.

[0047]

EXAMPLES The present invention will now be described with reference to production examples and test examples, but the present invention is not limited to the following examples. In the following examples, parts represent parts by weight (absolute dry parts by weight for yeast). First, a production example of the present invention will be shown. Production Example 1 2.5 parts of ethanol was added to 25 parts of a dispersion liquid containing 2.5 parts of commercially available baker's yeast (live yeast manufactured by Kanegafuchi Chemical Co., Saccharomyces cerevisiae), and the mixture was stirred at 40 ° C. for 24 hours to obtain yeast. The water-soluble components in the cells were eluted outside the cells, and the water-soluble components were removed by centrifugation to obtain a dispersion liquid of the yeast residue.
To the obtained dispersion liquid, 3 parts of Sumidule L and 5 parts of fenitrothion (organic phosphorus insecticidal active ingredient) were added, and stirred using a three-one motor, to which 1.5 parts of ethylene glycol and 0.5 part of polyvinyl alcohol were added. 40 parts of an aqueous solution containing T. K. An auto homomixer was used to deflocculate for 3 minutes under the conditions of a rotation speed of 4000 rpm and a temperature of 25 ° C. Next, the obtained suspension is subjected to a polymerization reaction while gently stirring for 3 hours under the conditions of a rotation speed of 100 rpm and a temperature of 60 ° C. using a three-one motor,
A dispersion liquid of the microencapsulated product was obtained. 2 parts Zanthan gum, 4 parts magnesium aluminum silicate,
Proxel GXL (2 parts), propylene glycol (5 parts) and pure water were added to adjust to 100 parts,
The composition (1) of the present invention was obtained.

Production Example 2 2.5 parts of ethanol was added to 25 parts of a dispersion liquid containing 2.5 parts of commercially available baker's yeast (live yeast produced by Kanegafuchi Chemical Co., Ltd.), and 2
After stirring for 4 hours, the water-soluble components in the yeast cells were eluted outside the cells, and the water-soluble components were removed by centrifugation to obtain a dispersion liquid of the yeast residue. To the obtained dispersion liquid, 6 parts of Sumidule L and 10 parts of fenitrothion were added and stirred using a three-one motor, and 50 parts of an aqueous solution containing 3 parts of ethylene glycol and 1 part of gum arabic as a dispersant. And T. K. It was deflocculated for 5 minutes with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 20 ° C. Next, the obtained suspension was subjected to a polymerization reaction using a three-one motor under the conditions of a rotation speed of 80 rpm and a temperature of 60 ° C. for 12 hours with gentle stirring to obtain a dispersion liquid of a microencapsulated product. Pure water is added to make 100
The composition of the present invention (2) was obtained.

Production Example 3 After adding 12 parts of Sumidule L to 20 parts of fenitrothion to form a uniform solution, 10 parts of commercially available baker's yeast (live yeast manufactured by Kanegafuchi Chemical Co., Ltd.) was added until the baker's yeast was uniformly dispersed. The mixture was stirred using a three-one motor and added to 45 parts of an aqueous solution containing 6 parts of ethylene glycol and 0.75 part of gum arabic as a dispersant. K. 1 with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 25 ° C.
Peptized for 0 minutes. Next, the obtained suspension was subjected to a polymerization reaction using a three-one motor at a rotation speed of 100 rpm and a temperature of 60 ° C. for 24 hours while gently stirring to obtain a dispersion liquid of a microencapsulated product. Further, 2 parts of xanthan gum, 4 parts of magnesium aluminum silicate, 2 parts of Proxel GXL and 5 parts of propylene glycol were added to obtain a composition (3) of the invention.

Production Example 4 6 parts of Sumidule L was added to 10 parts of cyanophos (organophosphorus insecticidal active ingredient) to form a uniform solution, and 3 parts of brewer's yeast (manufactured by Asahi Breweries) were added. The mixture was stirred using a three-one motor and added to 40 parts of an aqueous solution containing 0.5 part of polyvinyl alcohol as a dispersant.
K. An auto homomixer was used to deflocculate for 8 minutes under the conditions of a rotation speed of 8000 rpm and a temperature of 25 ° C. Next, 10 parts of an aqueous solution containing 3 parts of ethylene glycol was added dropwise to the obtained suspension, and the rotation speed was 100 r using a three-one motor.
Polymerization reaction was carried out under conditions of pm and temperature of 60 ° C. for 24 hours with gentle stirring to obtain a microencapsulated product. Further, 1 part of xanthan gum, 2 parts of magnesium aluminium silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to adjust to 100 parts to obtain a composition (4) of the invention.

Production Example 5 15 parts of Sumidule L was added to 25 parts of fenitrothion to form a uniform solution, and then 5 parts of brewer's yeast (manufactured by Asahi Breweries) were added. The mixture was stirred using a three-one motor and added to 45 parts of an aqueous solution containing 7.5 parts of ethylene glycol and 0.3 part of polyvinyl alcohol as a dispersion liquid. K. Rotation speed 700 with auto homomixer
Peptization was performed for 5 minutes under the conditions of 0 rpm and a temperature of 20 ° C. Next, the obtained suspension was subjected to a polymerization reaction using a three-one motor under the conditions of a rotation speed of 120 rpm and a temperature of 60 ° C. for 8 hours with gentle stirring to obtain a dispersion liquid of a microencapsulated product. Add pure water to this and add 100 to the total weight.
The composition of the present invention (5) was obtained.

Production Example 6 9 parts of Sumidule L were added to a mixed solution of 10 parts of fenitrothion, 0.5 part of fenvalerate (a pyrethroid insecticidal active ingredient) and 1 part of phenylxylylethane to obtain a uniform solution. 0.5 with ethylene glycol
30 parts by weight of an aqueous solution containing polyvinyl alcohol as a dispersant and T. K. An auto homomixer was used to deflocculate for 15 minutes under the conditions of a rotation speed of 9000 rpm and a temperature of 20 ° C. Next, the obtained suspension was added to 30 parts of a dispersion containing 7.5 parts of baker's yeast (Kanabuchi Kagaku's live yeast), and then a three-one motor was used to rotate at 100 rpm and a temperature of 65 ° C. for 8 hours. The polymerization reaction was carried out while gently stirring for a period of time to obtain a dispersion liquid of the microencapsulated product. To this, 2 parts of xanthan gum, 4 parts of magnesium aluminum silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to adjust the total weight to 100 parts to obtain the composition (6) of the present invention.

Production Example 7 3 parts of Sumidule L was added to a mixed solution of 5 parts of esfenvalerate (pyrethroid-based insecticidal active ingredient) and 10 parts of phenylxylylethane to prepare a uniform solution, and then baker's yeast (Kanebuchi) Chemically-produced yeast) (2.5 parts) and stirred using a three-one motor, and this was added to 50 parts of an aqueous solution containing 2 parts of gum arabic as a dispersant. K. It was deflocculated for 5 minutes with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 25 ° C. Next, 10 parts of an aqueous solution containing 1.5 parts by weight of ethylene glycol was added dropwise to the obtained suspension, and the rotation speed was 100 rpm using a three-one motor.
The polymerization reaction was carried out at a temperature of 60 ° C. for 3 hours with gentle stirring to obtain a dispersion liquid of the microencapsulated product. Pure water was added to this to adjust the total weight to 100 parts to obtain the composition (7) of the present invention.

Production Example 8 3 parts of Sumidule L was added to 5 parts of cyanophos to make a uniform solution, and this was added to 40 parts of an aqueous solution containing 1.5 parts of polyoxyethylene phenyl ether alkylaryl sulfonate as a dispersant to give T. K. It was deflocculated for 5 minutes with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 20 ° C. Next, 10 parts of a dispersion liquid containing 5 parts of beer yeast (manufactured by Asahi Breweries) and 1.5 parts of ethylene glycol was added to the obtained suspension, and the rotation speed was 100 rpm and the temperature was 55 ° C. using a three-one motor. Polymerization reaction was carried out under the condition of 36 hours with gentle stirring to obtain a dispersion liquid of the microencapsulated product. 1 part of xanthan gum, 2 parts of magnesium aluminum silicate, proxel G
2 parts of XL, 5 parts of propylene glycol and pure water were added to adjust the total amount to 100 parts to obtain the composition (8) of the present invention.

Production Example 9 10 parts of Sumidule L was added to fenitrothion 10 to form a uniform solution, 10 parts of brewer's yeast (manufactured by Asahi Breweries) were added, and the mixture was stirred using a three-one motor to give 5 parts of ethylene. T.coli was added to 50 parts of an aqueous solution containing glycol and 0.75 parts of gum arabic as a dispersant. K. Rotation speed 6000 rpm with an auto homomixer,
Peptization was performed for 3 minutes at a temperature of 25 ° C. Next, the obtained suspension is rotated at 90 rpm using a three-one motor.
m, the temperature was 55 ° C., the polymerization reaction was carried out for 48 hours with gentle stirring to obtain a dispersion liquid of the microencapsulated product. Pure water was added to this to prepare 100 parts by weight to obtain the composition (9) of the present invention.

Production Example 10 9 parts of Sumidule N was added to a mixed solution of 3 parts of cyphenothrin (a pyrethroid insecticidal active ingredient) and 6 parts of phenylxylylethane to prepare a uniform solution, which was then added to brewer's yeast (made by Asahi Breweries). 1 part) and stirred using a three-one motor. This was added to 50 parts of an aqueous solution containing 0.5 part of polyvinyl alcohol as a dispersant, and T.I. K. Using an auto homomixer, 10 was decomposed under the conditions of a rotation speed of 5500 rpm and a temperature of 30 ° C. Next, 10 parts of an aqueous solution containing 3 parts of ethylene glycol was added dropwise to the obtained suspension, and the number of revolutions was 150 rpm and the temperature was 5 using a three-one motor.
The polymerization reaction is carried out under the condition of 5 ° C with gentle stirring,
A dispersion liquid of the microencapsulated product was obtained. 2 parts of Zanthan gum, 4 parts of magnesium aluminum silicate,
Proxel GXL (2 parts), propylene glycol (5 parts) and pure water were added to prepare 100 parts,
The present composition (10) was obtained.

Production Example 11 3 parts of Sumidule L were added to 5 parts of fenitrothion,
After making a uniform solution, baker's yeast (Kanebuchi Chemical's live yeast) 1
Part, add and stir using a three-one motor.
T.V. was added to 40 parts of an aqueous solution containing 1.5 parts ethylene glycol and 1 part polyoxyethylene phenyl ether alkylaryl sulfonate as a dispersant. K. Rotation speed 3500 rpm, temperature 15 ° C with auto homomixer
The peptization was carried out for 3 minutes under the conditions of. Next, the obtained suspension was rotated at 100 rpm and a temperature of 6 using a three-one motor.
The polymerization reaction is carried out under the condition of 0 ° C with gentle stirring,
A microencapsulated product was obtained. Pure water was added to this to prepare 100 parts by weight of the composition (11) of the present invention.
I got

Production Example 12 6 parts of Sumidule L was added to 10 parts of fenitrothion to form a uniform solution, which was added to 25 parts of an aqueous solution containing 1 part of polyvinyl alcohol as a dispersant,
K. An auto homomixer was used to deflocculate for 10 minutes under the conditions of a rotation speed of 7,000 rpm and a temperature of 30 ° C. Next, the obtained suspension was added to 30 parts of an aqueous solution containing 3 parts of ethylene glycol and 10 parts of de-nucleic acid sanyo yeast (manufactured by Nippon Paper Industries Co., Ltd.), and the number of rotations was performed using a three-one motor. 120
The polymerization reaction was carried out under a condition of rpm and a temperature of 60 ° C. for 24 hours with gentle stirring to obtain a dispersion liquid of the microencapsulated product. To this, 2 parts of xanthan gum, 4 parts of magnesium aluminum silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to prepare 100 parts of the whole to obtain a composition (12) of the invention.

Production Example 13 After 6 parts of Sumidule L was added to 10 parts of cyanophos to form a uniform solution, 5 parts of de-nucleic acid Sanyo yeast (manufactured by Nippon Paper Industries Co., Ltd.) was added and stirred using a three-one motor. Was added to 60 parts of an aqueous solution containing 0.4 part of polyvinyl alcohol as a dispersant. K. 5 with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 25 ° C.
I defused for minutes. Next, 10 parts of an aqueous solution containing 3 parts of ethylene glycol was added dropwise to the obtained suspension, and then a polymerization reaction was performed using a three-one motor under conditions of a rotation speed of 100 rpm and a temperature of 60 ° C. while gently stirring. A dispersion liquid of the microencapsulated product was obtained. Zanthangum 1
Parts, 2 parts of magnesium aluminum silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to adjust to 100 parts to obtain a composition (13) of the invention.

Production Example 14 3 parts of Sumidule L was added to 5 parts of cyanophos to make a uniform solution, which was added to 40 parts of an aqueous solution containing 0.25 part of polyvinyl alcohol as a dispersant to give T. K. It was deflocculated for 5 minutes with an auto homomixer at a rotation speed of 1500 rpm and a temperature of 20 ° C. Next, 10 parts of an aqueous solution containing 5 parts of brewer's yeast (manufactured by Asahi Breweries) and 1.5 parts of ethylene glycol was added to the obtained suspension, and the rotation speed was 100 rpm and the temperature was 55 ° C. using a three-one motor. The polymerization reaction was carried out under mild conditions for 36 hours with gentle stirring to obtain a dispersion liquid of the microencapsulated product. To this, 1 part of xanthan gum, 2 parts of magnesium aluminum silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to adjust to 100 parts to obtain a composition (14) of the invention.

Production Example 15 3 parts of Sumidule L were added to 5 parts of fenitrothion,
A homogeneous solution was prepared, which was added to 40 parts of an aqueous solution containing 1 part of gum arabic as a dispersant, K. It was deflocculated for 5 minutes with an auto homomixer at a rotation speed of 5000 rpm and a temperature of 20 ° C. Next, 10 parts of an aqueous solution containing 10 parts of brewer's yeast (manufactured by Asahi Breweries) and 1.5 parts of ethylene glycol was added to the obtained suspension, and the rotation speed was 100 rpm and the temperature was 55 ° C. using a three-one motor. The polymerization reaction was carried out under conditions under gentle stirring for 24 hours to obtain a dispersion liquid of the microencapsulated product. To this, 1 part of xanthan gum, 2 parts of magnesium aluminum silicate, 2 parts of proxel GXL, 5 parts of propylene glycol and pure water were added to adjust to 100 parts to obtain the composition (15) of the present invention.

Next, a production example of an agrochemical composition using yeast as a microcapsule coating, which was used for comparison in the test examples described later, is shown below as a comparative production example. Comparative Production Example 1 Comparative composition (1) was prepared in the same manner as in Production Example 1 except that Sumidule L and ethylene glycol were not added.
I got Comparative Production Example 2 Comparative composition (2) was prepared in the same manner as in Production Example 2 except that Sumidule L and ethylene glycol were not added.
I got Comparative Production Example 3 Comparative composition (3) was prepared in the same manner as in Production Example 3 except that Sumidule L and ethylene glycol were not added.
I got Comparative Production Example 4 Comparative composition (4) was prepared in the same manner as in Production Example 4 except that Sumidule L and ethylene glycol were not added.
I got

Test Example 1 The encapsulation rate at the time of production was measured for each of the compositions (1) to (4) of the present invention, the comparative composition (1) and the comparative composition (4). The encapsulation rate was measured by the following operation. First, the total amount of active ingredients of the composition was determined using gas chromatography. Next, decane was added to the composition, and after shaking, the amount of uncapsules in the decane (amount of free active ingredient) was determined by gas chromatography. The encapsulation rate (%) is

[Equation 1] It was calculated by The results are shown in Table 1.

[0064]

[Table 1] As seen in the above table, according to the production method of the present invention, a high encapsulation rate can be achieved with a simple operation.

Test Example 2 For each of the compositions (1) to (3) of the present invention, the comparative composition (1) and the comparative composition (3), at the time of production and at 60 ° C.
The encapsulation rate (%) after storage for 1 month was measured in the same manner as in Test Example 1. Table 2 shows the percentage of the encapsulation rate (%) of each composition after storage at 60 ° C. for 1 month, when the encapsulation rate (%) at the time of production was 100.

[Table 2] As can be seen from the above table, the composition of the present invention shows little decrease in encapsulation rate even after one month, and has a long-term heat resistance effect.

Test Example 3 Each of the compositions (1) to (3) of the present invention and the comparative composition (1) was diluted with pure water, and the amount of the active ingredient compound was about 0.3 mg in a petri dish having an inner diameter of 6 cm. As applied. After air-drying at room temperature, it was stored at 40 ° C., and one month later, the amount of the active ingredient compound remaining in the petri dish was determined by gas chromatography. Table 3 shows the residual ratio (%) of the active ingredient compounds.

[Table 3] As is clear from the above table, it is recognized that the composition of the present invention has a high residual ratio of the active ingredient compound even after one month.

[0067]

INDUSTRIAL APPLICABILITY The composition of the present invention is one in which the active ingredient compound is stably maintained in an encapsulated state for a long period of time, and the composition of the present invention having a high encapsulation rate is produced by a simple operation. It is also extremely useful because it is possible.

 ─────────────────────────────────────────────────── ─── Continuation of front page (72) Inventor Toshiro Otsubo 4-2-1 Takashi, Takarazuka-shi, Hyogo Sumitomo Chemical Co., Ltd. (72) Inventor Mamoru Ishiguro 3-4-2 Marunouchi, Chiyoda-ku, Tokyo Sanryo Paper Co., Ltd.

Claims (2)

[Claims] 1. A pesticide composition characterized in that a pesticidal active ingredient which is a pest controlling active ingredient or a plant growth regulating active ingredient is encapsulated in microcapsules consisting of yeast and polyurethane and / or polyurea resin. Stuff. 2. When a yeast cell contains a pesticidal active ingredient or a pesticidal active ingredient which is a plant growth regulating active ingredient, interfacial polymerization between a polyfunctional polyisocyanate monomer and a polyhydric alcohol and / or water is carried out. The method for producing the agricultural chemical composition according to claim 1, wherein