JPH09241127A - Body reducing agent composition for cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic for body reducing having a body reducing effect, and body reducing agent. SOLUTION: This cosmetic for body reducing or body reducing agent contains extracts of Citrus unshiu Mercov., Thea sinensis, Nelumbo nucifera Gaertn. Panax ginseng, Marticaria chamomilla or Lithospermi radix. As for the respective components, the extracts of the Citrus Wnshiw Marcov, Thea sinensis, Nelumbo nucifera gaertn., Panax ginseng, Matricaria chamomilla and Lithospermi radix all of which are commercially available, can be used. The formulation such as a fundamental cosmetic, a cosmetic for makeup, a bathing agent or a soap be adopted as the cosmetic for body reducing, and the formulation such as powder, a pill, a tablet, a preparation for external use, an injection or a suppository can be adopted as the body reducing agent.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention relates to a slimming cosmetic composition and a slimming agent, which contains one or more kinds of extracts selected from chimpi, tea, lotus, ginseng, chamomile and shikon. Regarding

[0002]

2. Description of the Related Art Generally, obesity is one of the constituents of the body.
A state in which the proportion of adipose tissue is abnormally increased. That is, when the body takes in more energy than it needs, the excess energy is converted into fat (triglyceride) by the fat cells that make up the adipose tissue, which is abnormally accumulated in the fat cells and leads to obesity. Is done. A commonly used method of promoting the breakdown of these accumulated fats consists of inhibiting phosphodiesterase to prevent or at least limit the degradation of cyclic AMP.

[0003]

The various phosphodiesterase inhibitors that have been conventionally recommended as slimming agents include xanthine derivatives, especially caffeine.
In Japan, the blending amount is limited and the action of decomposing fat is not sufficient. Therefore, as a result of repeated studies to obtain a cosmetic having a strong lipolytic action and an excellent slimming effect, the present inventors have found that extracts of chimpi, tea, lotus, ginseng, chamomile and shikon are sufficiently lipolytic. It was found that the effect was exhibited and the slimming effect was excellent, and the present invention was completed based on this finding.

[0004]

That is, the present invention provides a cock,
A slimming cosmetic composition and a slimming agent, which comprises one or more kinds of extracts selected from tea, lotus meat, ginseng, chamomile and shikon. Commercially available extracts of chimpi, tea, lotus, ginseng, chamomile and shikon used in the present invention can be used. In addition, commercially available crude drugs (chimp, lotus meat, ginseng, shikon), tea leaves, chamomile flowers, whole plants and the like can also be extracted by a conventional method and used. For example, water, ethanol, 1,
Extract by adding a single or mixed solvent such as 3-butylene glycol or propylene glycol. The extraction may be performed at room temperature or may be heated, and the solvent may be distilled off after the extraction.

Extracts of chimpi, tea, lotus meat, ginseng, chamomile, and shikon are each contained in the slimming cosmetic composition or slimming agent of the present invention in an amount of 0.001 to 20% by weight, preferably,
It is possible to add 0.01 to 10.0% by weight. At a concentration of 0.001% or less, a sufficient effect cannot be obtained, and at a concentration of 20% by weight or more, the effect is not enhanced and it is uneconomical. The slimming cosmetics and slimming agents of the present invention include oils and fats used in cosmetics and medicines, waxes, etc. within a range that does not impair the effects of chimp, tea, lotus meat, ginseng, chamomile and shikon extract. Raw materials such as compounds, hydrocarbons, fatty acids, alcohols, esters, and surfactants can be blended. The slimming cosmetic of the present invention includes creams, lotions, emulsions,
Basic cosmetics such as packs, makeup cosmetics such as foundations and lipsticks, bath agents, and dosage forms such as soaps can be adopted. Further, the slimming agent of the present invention has a dosage form such as powder, pill, tablet, injection, suppository, external preparation, etc., and is manufactured according to a usual formulation technique. The daily dose is 1 mg to 100 mg, preferably 2 mg to 50 mg,
It can be administered in three divided doses.

[0006]

EXAMPLES Next, the present invention will be described in detail with reference to Examples, but the present invention is not limited thereto. The parts of the amounts shown in the examples are parts by weight.

Example-1 Lotion Formulation Compounding amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Chinpi Extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. .

Example-2 Lotion Formulation Amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Tea Extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. .

Example-3 Lotion Formulation Formulation amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Chinpi Extract 5.0 7. Tea extract 5.0 8.1,3-butylene glycol 3.0 9. Glycerin 2.0 10. Xanthan gum 0.02 11. Purified water 64.6 Manufacturing method: Components 1 to 5 and components 6 to 11 are uniformly dissolved and mixed. The product is filtered.

Example-4 Lotion Formulation Compounding amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Lotus Meat extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. To do.

Example-5 Lotion Formulation Blending amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Koryo Ginseng extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. To do.

Example-6 Lotion Formulation Compounding amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Chamomile Extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. .

Example-7 Lotion Formulation Compounding amount 1. Ethanol 5.0 parts 2. Methyl P-oxybenzoate 0.1 3. Polyoxyethylene (40) hydrogenated castor oil 0.1 4. Perfume proper amount 5. Purified water 10.0 6. Sikon Extract 5.0 7.1,3-butylene glycol 3.0 8. Glycerin 2.0 9. Xanthan gum 0.02 10. Purified water 69.6 Manufacturing method: Components 1 to 5 and components 6 to 10 are uniformly dissolved, mixed and filtered to obtain a product. .

Comparative Example-1 Conventional lotion A conventional lotion was obtained by replacing the thimpy extract and tea extract with purified water in Example-3.

Example-8 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Chinpi extract 2.0 11. Methyl P-oxybenzoate 0.2 12. Purified water 63.5 13. Perfume suitable amount Production method: Oil phase component 1 ~ 7 and the water phase components 8 to 12 are heated and dissolved at 70 to 75 ° C, respectively, and then the oil phase components 1 to 7 are added to the water phase components.
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-9 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Tea extract 2.0 11. P-Methyl oxybenzoate 0.2 12. Purified water 63.5 13. Perfume Suitable amount Production method: Oil phase component 1 ~ 7 and the water phase components 8 to 12 are heated and dissolved at 70 to 75 ° C, respectively, and then the oil phase components 1 to 7 are added to the water phase components.
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-10 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Chinpi extract 2.0 11. Tea extract 2.0 12. Methyl p-oxybenzoate 0.2 13. Purified water 61.5 14. Perfume suitable amount Manufacturing method : Oil phase components 1 to 7 and water phase components 8 to 13 are heated and melted at 70 to 75 ° C, respectively, and then water phase components are added to oil phase components 1 to 7.
Add 8 to 13 to emulsify, add component 14 on the way of cooling and mix, and cool to 30 ° C to obtain a product.

Example-11 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Lotus root extract 2.0 11. Methyl P-oxybenzoate 0.2 12. Purified water 63.5 13. Perfume suitable amount Manufacturing method: Oil phase component 1 ~ 7 and water phase components 8 ~ 12 are heated and dissolved at 70 ~ 75 ℃, respectively, then the oil phase components 1 ~ 7
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-12 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Ginseng extract 2.0 11. Methyl P-oxybenzoate 0.2 12. Purified water 63.5 13. Perfume suitable amount Production method: Oil phase component 1 ~ 7 and water phase components 8 ~ 12 are heated and dissolved at 70 ~ 75 ℃, respectively, then the oil phase components 1 ~ 7
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-13 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Chamomile extract 2.0 11. Methyl P-hydroxybenzoate 0.2 12. Purified water 63.5 13. Perfume suitable amount Production method: Oil phase component 1 ~ 7 and the water phase components 8 to 12 are heated and dissolved at 70 to 75 ° C, respectively, and then the oil phase components 1 to 7 are added to the water phase components.
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-14 Cream Formulation Amount 1. Liquid paraffin 6.5 parts 2. Vaseline 10.0 3. Stearic acid 4.0 4. Cetyl alcohol 3.0 5. Stearyl alcohol 1.0 6. Polyoxyethylene (25) monostearate 3.0 7. Sorbitan monostearate 2.5 8.1,3-Butylene glycol 5.0 9. Potassium hydroxide 0.1 10. Sikon extract 2.0 11. Methyl P-oxybenzoate 0.2 12. Purified water 63.5 13. Perfume suitable amount Production method: Oil phase component 1 ~ 7 and the water phase components 8 to 12 are heated and dissolved at 70 to 75 ° C, respectively, and then the oil phase components 1 to 7 are added to the water phase components.
Add 8 to 12 to emulsify, add and mix component 13 while cooling, and cool to 30 ° C to obtain a product.

Example-15 Emulsion formulation Formulation amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Chinpi extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume proper quantity Production method: Oil phase components 1 to 6 and aqueous phase components 7 to 70, respectively 70 to 75 After dissolving by heating at ℃, the water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Example-16 Emulsion Formulation Amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Tea extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume suitable amount Production method: Oil phase components 1 to 6 and aqueous phase components 7 to 70 respectively 70 to 75 After dissolving by heating at ℃, the water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Example-17 Emulsion formulation Formulation amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Chinpi extract 1.0 9. Tea extract 1.0 10. Methyl P-oxybenzoate 0.2 11. Purified water 75.1 12. Perfume suitable amount Production method: Oil phase components 1 to 6 and water phase component 7 to After heating and dissolving 11 to 70-75 ℃ respectively, add oil phase components 1 to 6 to aqueous phase components.
Add 7 to 11 to emulsify, add component 12 while cooling and mix, and cool to 30 ° C to obtain a product.

Example-18 Emulsion Formulation Compounding amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Lotus meat extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume suitable amount Production method: Oil phase components 1 to 6 and water phase components 7 to 70 respectively After melting by heating at 75 ℃, water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Example-19 Emulsion Formulation Amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Ginseng extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume suitable amount Manufacturing method: Oil phase components 1 to 6 and aqueous phase components 7 to 70 respectively After melting by heating at 75 ℃, water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Example-20 Emulsion Formulation Compounding amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Chamomile extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume suitable amount Manufacturing method: Oil phase components 1 to 6 and water phase components 7 to 70 respectively 70 to 75 After dissolving by heating at ℃, the water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Example-21 Emulsion Formulation Amount 1. Liquid paraffin 8.0 parts 2. Squalane 2.0 3. Stearyl alcohol 2.0 4. Sorbitan monooleate 2.5 5. Glycerin monostearate 2.3 6. Polyoxyethylene (10) sorbitan monooleate 0.8 7. Glycerin 6.0 8. Sikon extract 1.0 9. Methyl P-oxybenzoate 0.2 10. Purified water 76.1 11. Perfume suitable amount Production method: Oil phase components 1 to 6 and aqueous phase components 7 to 70, respectively 70 to 75 After dissolving by heating at ℃, the water phase components 1 to 6
Add 7 to 10 to emulsify, add component 11 while mixing, mix and cool to 30 ° C to obtain a product.

Comparative Example-2 Conventional Emulsion In Example-17, the conventional emulsion was obtained by replacing the thimpy extract and tea extract with purified water.

Example-22 Pack Packing Formulation amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Chimpi extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Production method: Dissolve each component uniformly to obtain a product.

Example-23 Pack Formulation Amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Tea extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Manufacturing method: Dissolve each component uniformly to obtain a product.

Example-24 Pack Formulation amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Chimpi extract 1.0 7. Tea extract 1.0 8. Citric acid 0.1 9. Sodium citrate 0.3 10. Perfume 0.1 11. Purified water 72.8 Manufacturing method: Dissolve each component uniformly to make a product.

Example-25 Pack Packing Formulation amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-Butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Lotus extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Manufacturing method: Dissolve each component uniformly to obtain a product.

Example-26 Pack Packing Formulation amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Ginseng extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Manufacturing method: Dissolve each component uniformly to obtain a product.

Example-27 Pack Formulation Amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Chamomile extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Production method: Dissolve each component uniformly to obtain a product.

Example-28 Packing Formulation amount 1. Polyvinyl alcohol 12.0 parts 2. Ethyl alcohol 5.0 3.1,3-butylene glycol 8.0 4. Methyl P-oxybenzoate 0.2 5. Polyoxyethylene (40) hydrogenated castor oil 0.5 6. Sikon extract 1.0 7. Citric acid 0.1 8. Sodium citrate 0.3 9. Perfume 0.1 10. Purified water 73.8 Production method: Dissolve each component uniformly to obtain a product.

Example-29 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Chinpi extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Tri Ethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance Suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-30 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Tea extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Tri Ethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance Suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-31 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.2 10. Chinpi extract 0.1 11. Tea extract 0.1 12. Sodium carboxymethylcellulose 0.1 13. Bentonite 0.5 14. Propylene glycol 4.0 15. Triethanolamine 1.1 16. P-Methyl oxybenzoate 0.2 17. Titanium oxide 8.0 18. Talc 4.0 19. Color pigment 5.0 20. Perfume suitable amount Manufacturing method: Ingredients 10 to 14 and 16 are heated to 70 ° C. Swell well. Ingredients 9 and 15 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. Components 17 to 19 which are well mixed and pulverized through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to this aqueous phase while stirring and cooled, and component 20 is added at 45 ° C, and the product is cooled with stirring.

Example-32 Foundation Formulation amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Spinach extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Triethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-33 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Ginseng extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Triethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-34 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Chamomile extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Tri Ethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance Suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-35 Foundation Formulation Amount 1. Stearic acid 2.4 parts 2. Polyoxyethylene (20) sorbitan monostearate 1.0 3. Polyoxyethylene (20) cetyl ether 2.0 4. Cetyl alcohol 1.0 5. Liquid lanolin 2.0 6. Liquid paraffin 3.0 7. Isopropyl myristate 6.5 8. Butyl P-hydroxybenzoate 0.1 9. Purified water 58.3 10. Sikon extract 0.1 11. Carboxymethylcellulose sodium 0.1 12. Bentonite 0.5 13. Propylene glycol 4.0 14. Tri Ethanolamine 1.1 15. Methyl P-oxybenzoate 0.2 16. Titanium oxide 8.0 17. Talc 4.0 18. Coloring pigment 5.0 19. Fragrance Suitable amount Production method: Components 10 to 13 and 15 are heated to 70 ° C. and swelled well. Ingredients 9 and 14 are dissolved in this to obtain an aqueous phase. Components 1 to 8 are dissolved by heating and kept at 80 ° C. to form an oil phase. The components 16 to 18 mixed well and passed through a pulverizer are added to the aqueous phase, and the mixture is stirred with a homomixer and kept at 75 ° C. The oil phase is added to the aqueous phase with stirring, cooled, and the component 19 is added at 45 ° C., and cooled with stirring to obtain a product.

Example-36 Bath agent Formulation amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogen carbonate 50.0 3. Chinpi extract 5.0 4. Yellow (202) (1) Appropriate amount 5. Perfume proper amount Manufacturing method: Each component Mix well to make a product.

Example-37 Bath Agent Formulation Compounding amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogencarbonate 50.0 3. Tea extract 5.0 4. Yellow (202) (1) Appropriate amount 5. Perfume suitable amount Production method: Each component Mix well to make a product.

Example-38 Bath agent Formulation amount 1. Sodium sulfate 43.0 parts 2. Sodium hydrogen carbonate 50.0 3. Chinpi extract 5.0 4. Tea extract 5.0 5. Yellow No. 202 (1) proper amount 6. perfume proper amount Manufacturing method: Mix each component well to make a product.

Example-39 Bath Agent Formulation Amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogen carbonate 50.0 3. Lotus meat extract 5.0 4. Yellow 202 (1) proper amount 5. Perfume proper amount Manufacturing method: Each component Is mixed well to make a product.

Example-40 Bath Agent Formulation Amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogencarbonate 50.0 3. Ginseng extract 5.0 4. Yellow (202) (1) Appropriate amount 5. Perfume suitable amount Manufacturing method: Each component Is mixed well to make a product.

Example-41 Bath agent Formulation amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogen carbonate 50.0 3. Chamomile extract 5.0 4. Yellow (202) (1) Appropriate amount 5. Perfume suitable amount Manufacturing method: each component Mix well to make a product.

Example-42 Bath Agent Formulation Amount 1. Sodium sulfate 48.0 parts 2. Sodium hydrogen carbonate 50.0 3. Sikon extract 5.0 4. Yellow (202) (1) Appropriate amount 5. Perfume Appropriate amount Manufacturing method: Each component Mix well to make a product.

Example-43 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Chinpi extract 1.0 4. White petrolatum 89.0 Manufacturing method: Mix the components well to obtain a product.

Example-44 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Tea extract 1.0 4. White petrolatum 89.0 Manufacturing method: Mix the components well to obtain a product.

Example-45 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Chinpi extract 1.0 4. Tea extract 1.0 5. White petrolatum 88.0 Production method: Mix each component well Product.

Example-46 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Lotus root extract 1.0 4. White petrolatum 89.0 Manufacturing method: Mix the components well to obtain a product.

Example-47 Oil and Ointment Formulation Compounding amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Ginseng extract 1.0 4. White petrolatum 89.0 Manufacturing method: Mix the components well to obtain a product.

Example-48 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Chamomile extract 1.0 4. White petrolatum 89.0 Production method: Mix the components well to obtain a product.

Example-49 Oily Ointment Formulation Amount 1. Purified lanolin 5.0 parts 2. White beeswax 5.0 3. Sikon extract 1.0 4. White vaseline 89.0 Manufacturing method: Mix the components well to obtain a product.

Comparative Example-3 Conventional Oily Ointment A conventional oily ointment was obtained by replacing the chimp extract and tea extract with white petrolatum in Example-45.

Example-50 Emulsion Ointment Formulation Content 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulfate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Chimpi extract 1.0 8. Purified water 38.46 Production method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-51 Emulsion Ointment Formulation Amount 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulphate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Tea extract 1.0 8. Purified water 38.46 Production method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-52 Emulsion Ointment Formulation Content 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulphate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Chimpi extract 1.0 8. Tea extract 1.0 9. Purified water 37.46 Manufacturing method: Oil phase components 1-2 and water phase components 3-9, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 9 to emulsify and cool to 30 ℃ to obtain the product.

Example-53 Emulsion Ointment Formulation Amount 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulfate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Spinach extract 1.0 8. Purified water 38.46 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-54 Emulsion Ointment Formulation amount 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulfate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Ginseng extract 1.0 8. Purified water 38.46 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-55 Emulsion Ointment Formulation Amount 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulfate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Chamomile extract 1.0 8. Purified water 38.46 Production method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-56 Emulsion Ointment Formulation amount 1. White petrolatum 25.0 2. Stearyl alcohol 22.0 3. Propylene glycol 12.0 4. Sodium lauryl sulfate 1.5 5. Ethyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.015 7. Sikon extract 1.0 8. Purified water 38.46 Production method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-57 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Chinpi extract 1.0 5. White petrolatum 85.0 Manufacturing method: 70-75 ° C. by mixing each component After melting by heating to
Cool to 30 ° C to obtain the product.

Example-58 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Tea extract 1.0 5. White petrolatum 85.0 Manufacturing method: 70-75 ° C. by mixing each component After melting by heating to
Cool to 30 ° C to obtain the product.

Example-59 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Chinpi extract 1.0 5. Tea extract 1.0 6. White petrolatum 84.0 Production method: Each component After mixing and melting by heating at 70-75 ℃,
Cool to 30 ° C to obtain the product.

Example-60 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Lotus root extract 1.0 5. White petrolatum 85.0 Production method: 70-75 by mixing each component After melting by heating to ℃,
Cool to 30 ° C to obtain the product.

Example-61 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Ginseng extract 1.0 5. White petrolatum 85.0 Production method: 70-75 by mixing each component After melting by heating to ℃,
Cool to 30 ° C to obtain the product.

Example-62 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Chamomile extract 1.0 5. White vaseline 85.0 Production method: 70-75 ° C. by mixing each component After melting by heating to
Cool to 30 ° C to obtain the product.

Example-63 Emulsion Ointment Formulation Amount 1. Cholesterol 3.0 2. Stearyl alcohol 3.0 3. White beeswax 8.0 4. Sikon extract 1.0 5. White petrolatum 85.0 Production method: Each component is mixed at 70 to 75 ° C. After melting by heating to
Cool to 30 ° C to obtain the product.

Example-64 Water-soluble ointment Formulation amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Chinpi extract 2.0 Production method: Dissolve each component uniformly to obtain a product.

Example-65 Water-soluble ointment Formulation amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Tea extract 2.0 Production method: Dissolve each component uniformly to obtain a product.

Example-66 Water Soluble Ointment Formulation Amount 1. Polyethylene glycol 4000 48.0 2. Polyethylene glycol 400 48.0 3. Chinpi extract 2.0 4. Tea extract 2.0 Production method: Each component is uniformly dissolved to obtain a product. .

Example-67 Water-soluble ointment Formulation amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Lotus root extract 2.0 Production method: Dissolve each component uniformly to obtain a product.

Example-68 Water-soluble ointment Formulation amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Korean ginseng extract 2.0 Production method: Dissolve each component uniformly to obtain a product.

Example-69 Water Soluble Ointment Formulation Amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Chamomile extract 2.0 Manufacturing method: Each component is uniformly dissolved to obtain a product.

Example-70 Water-soluble ointment Formulation amount 1. Polyethylene glycol 4000 50.0 2. Polyethylene glycol 400 48.0 3. Sikon extract 2.0 Production method: Each component is uniformly dissolved to obtain a product.

Example-71 Lotion Formulation Compounding amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Chinpi Extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-72 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Tea Extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-73 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Chinpi Extract 5.0 8. Tea extract 5.0 9. Purified water 49.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-9, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 9 to emulsify and cool to 30 ℃ to obtain the product.

Example-74 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Lotus Meat extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-75 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Koryo Ginseng extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-76 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Chamomile Extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-77 Lotion formulation Formulation amount 1. Stearyl alcohol 2.5 2. Liquid paraffin 25.0 3. Sodium lauryl sulfate 1.0 4. Propylene glycol 12.0 5. Methyl paraoxybenzoate 0.025 6. Propyl paraoxybenzoate 0.025 7. Sicon Extract 5.0 8. Purified water 54.45 Manufacturing method: Oil phase components 1-2 and water phase components 3-8, respectively
After heating and melting at 70-75 ° C, the aqueous phase component 3
Add ~ 8 to emulsify and cool to 30 ℃ to obtain the product.

Example-78 Tablet Formulation Compounding amount 1. Chinpi extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 2.0 production Method: Chimpi extract, corn starch, purified sucrose, carboxymethyl cellulose calcium, and microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. Talc was added as a lubricant to the mixture, and the mixture was tabletted into 100 mg tablets.

Example-79 Tablet formulation Formulation amount 1. Tea extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 2.0 production Method: Tea extract, corn starch, purified sucrose, carboxymethylcellulose calcium, and microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. Talc was added as a lubricant to the mixture, and the mixture was tabletted into 100 mg tablets.

Example-80 Tablets Formulation amount 1. Chimpi extract 10.0 parts 2. Tea extract 10.0 3. Corn starch 10.0 4. Purified sucrose 20.0 5. Carboxymethylcellulose calcium 10.0 6. Microcrystalline cellulose 25.0 7. Polyvinylpyrrolidone 5.0 8. Talc 2.0 Manufacturing method: Chimpi extract, tea extract, corn starch, purified sucrose, carboxymethylcellulose calcium, microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. . After adding talc as a lubricant to this and blending,
Each tablet was compressed into 100 mg tablets.

Example-81 Tablet Formulation Compounding amount 1. Lotus meat extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 2.0 Production method: Lotus root extract, corn starch, purified sucrose, carboxymethyl cellulose calcium, and microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. Talc was added as a lubricant to the mixture, and the mixture was tabletted into 100 mg tablets.

Example-82 Tablet Formulation Amount 1. Ginseng extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 2.0 Production method: Ginseng extract, corn starch, purified sucrose, carboxymethylcellulose calcium, and microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. After adding talc as a lubricant to this and blending, 1 tablet 100 mg
Was compressed into tablets.

Example-83 Tablet Formulation Compounding amount 1. Chamomile extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 2.0 production Method: Chamomile extract, corn starch, purified sucrose, carboxymethyl cellulose calcium, microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. After adding talc as a lubricant to this and blending, 1 tablet 100 mg
Was compressed into tablets.

Example-84 Tablet Formulation Compounding amount 1. Sikon extract 10.0 parts 2. Corn starch 10.0 3. Purified sucrose 20.0 4. Carboxymethylcellulose calcium 10.0 5. Microcrystalline cellulose 35.0 6. Polyvinylpyrrolidone 5.0 7. Talc 10.0 Production Method: Sikon extract, corn starch, purified sucrose, carboxymethylcellulose calcium and microcrystalline cellulose were mixed, and then an aqueous solution of polyvinylpyrrolidone was added as a binder to granulate by a conventional method. Talc was added as a lubricant to the mixture, and the mixture was tabletted into 100 mg tablets.

Example-85 Powder formulation Formulation amount 1. Chimpi extract 10 parts 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above components were mixed and made into a powder by a conventional method.

Example-86 Powder formulation Formulation amount 1. Tea extract 10 parts 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above components were mixed and made into a powder by a conventional method.

Example-85 Powder formulation Formulation amount 1. Chimpi extract 10 parts 2. Tea extract 10 3. Corn starch 40 4. Microcrystalline cellulose 50 Production method: The above ingredients were mixed and made into a powder by a conventional method. .

Example-86 Powder formulation Formulation amount 1. Lotus meat extract 100 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above components were mixed and made into a powder by a conventional method.

Example-87 Powder formulation Formulation amount 1. Ginseng extract 10 parts 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above ingredients were mixed and made into a powder by a conventional method.

Example-88 Powder formulation Formulation amount 1. Chamomile extract 10 parts 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above ingredients were mixed and made into a powder by a conventional method.

Example-89 Powder Formulation Compounding amount 1. Sikon extract 10 parts 2. Corn starch 40 3. Microcrystalline cellulose 50 Production method: The above components were mixed and made into a powder by a conventional method.

Example-90 Injectable formulation Formulation amount 1. Chimpi extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphate buffer Liquid (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Production method: Chimpi extract, polyoxyethylene (60) hydrogenated castor oil, sesame oil and half of propylene glycol are mixed and dissolved by heating at about 80 ° C. To this, a phosphate buffer solution and distilled water in which sodium chloride and propylene glycol were previously dissolved were heated to about 80 ° C and added to give an aqueous solution having a total volume of 1000 ml. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-91 Injectable formulation Formulation amount 1. Tea extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphate buffer Liquid (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Manufacturing method: Tea extract, polyoxyethylene (60) hydrogenated castor oil, sesame oil and half of propylene glycol are mixed and dissolved by heating at about 80 ° C, To this, a phosphate buffer solution and distilled water in which sodium chloride and propylene glycol were previously dissolved were heated to about 80 ° C and added to give an aqueous solution having a total volume of 1000 ml. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-92 Injectable formulation Formulation amount 1. Chimpi extract 10.0 parts 2. Tea extract 10.0 3. Polyoxyethylene (60) hydrogenated castor oil 37.0 4. Sesame oil 2.0 5. Sodium chloride 9.0 6. Propylene glycol 40.0 7. Phosphate buffer (0.1M, pH 6.0) 100.0 8. Distilled water 792.0 Manufacturing method: Mix thimpi extract, tea extract, polyoxyethylene (60) hydrogenated castor oil, sesame oil and half amount of propylene glycol. Dissolve by heating at about 80 ° C, and add phosphate buffer and distilled water in which sodium chloride and propylene glycol are dissolved in advance to about 80 ° C to add 1000
It was an aqueous solution of ml. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-93 Injection formulation Formulation amount 1. Lotus root extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphoric acid Buffer solution (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Manufacturing method: Lotus root extract, polyoxyethylene (60) hydrogenated castor oil, sesame oil and half of propylene glycol are mixed and dissolved by heating at about 80 ℃. Then, a phosphate buffer solution and distilled water in which sodium chloride and propylene glycol were previously dissolved were heated to about 80 ° C. and added to give a total volume of 1000 ml of an aqueous solution. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-94 Injectable formulation Formulation amount 1. Ginseng extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphoric acid Buffer solution (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Manufacturing method: Ginseng extract, polyoxyethylene (60)
Hardened castor oil, sesame oil and half the amount of propylene glycol are mixed and dissolved by heating at about 80 ° C, and then phosphate buffer and distilled water in which sodium chloride and propylene glycol are previously dissolved are heated at about 80 ° C. A total of 1000 ml of aqueous solution was added. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-95 Injection formulation Formulation amount 1. Chamomile extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphate buffer Liquid (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Manufacturing method: Chamomile extract, polyoxyethylene (60)
Hardened castor oil, sesame oil and half the amount of propylene glycol are mixed and dissolved by heating at about 80 ° C, and then phosphate buffer and distilled water in which sodium chloride and propylene glycol are previously dissolved are heated at about 80 ° C. A total of 1000 ml of aqueous solution was added. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

Example-96 Injection formulation Formulation amount 1. Sikon extract 10.0 parts 2. Polyoxyethylene (60) hydrogenated castor oil 37.0 3. Sesame oil 2.0 4. Sodium chloride 9.0 5. Propylene glycol 40.0 6. Phosphate buffer Liquid (0.1M, pH 6.0) 100.0 7. Distilled water 802.0 Manufacturing method: Sikon extract, polyoxyethylene (60) hydrogenated castor oil, sesame oil and half of propylene glycol are mixed and dissolved by heating at about 80 ° C. To this, a phosphate buffer solution and distilled water in which sodium chloride and propylene glycol were previously dissolved were heated to about 80 ° C and added to give an aqueous solution having a total volume of 1000 ml. This aqueous solution was dispensed into a 1 ml ampoule, melted and sealed, and then heat sterilized.

[0108]

The slimming cosmetic composition and slimming agent of the present invention have excellent lipolytic activity and slimming effect. Next, the effects of the slimming cosmetic composition and slimming agent of the present invention will be described in more detail with reference to experimental examples.

Experimental Example-1 Lipolytic activity test using rat epididymal adipocytes Epididymal adipose tissue was excised from Wistar male rats, cut into small pieces, and then treated with collagenase to obtain adipocytes. Obtained adipocytes 2 × 10 ⁴ in ethanol extract of chimpi, hot water extract of tea, hot water extract of lotus root, hot water extract of ginseng, hot water extract of chamomile and 1,3-butylene glycol of shikon The reaction was started by adding the extract. After 1 hour, the reaction was stopped, and the fatty acid contained in the reaction solution was measured using a fatty acid quantification kit. As a result, the ethanol extract of Chinpi 0.5mg / ml, tea hot water extract 0.5mg / m
l, lotus hot water extract 1.0mg / ml, ginseng hot water extract 1.0mg
/ ml, chamomile hot water extract 5.0 mg / ml, and 1,3-butylene glycol extract of shikon 1.0 mg / ml or more showed lipolytic activity (Table 1). Among them, a particularly strong action was observed in combination of chimpi ethanol extract and hot tea water extract and hot water extract of lotus root.

[0110]

[Table 1] Table 1 Lipolytic activity ──────────────────────────────────── Sample (sample concentration) Fatty acid content (mEq / l) Lipolysis promotion rate (%) ───────────────────────────────────── Control 0.095 Chimpi extract (0.5 mg / ml) 0.222 233 Chimpi extract (1.0 mg / ml) 0.318 335 Tea extract (3.0 mg / ml) 0.258 272 Tea extract (10.0 mg / ml) 0.236 248 Chimpi extract ( 0.25mg / ml) + tea extract (0.5mg / ml) 0.523 550 chimpi extract (0.5mg / ml) + tea extract (1.0mg / ml) 1.107 1165 lotus meat extract (1.0mg / ml) 0.192 202 Lotus root extract (3.0mg / ml) 1.561 1643 Ginseng extract (1.0mg / ml) 0.200 211 Ginseng extract (3.0mg / ml) 0.306 322 Chamomile extract (5.0mg / ml) 0.163 172 Sikon extract (1.0mg / ml) 0.203 214 ────────────────────────────────────

Experimental Example-2 Usage Test Lotions of Examples-3 and 4, Examples-17 and 18
30 women (30 to 45 years old) using the milky lotion of No. 3, the conventional lotion of Comparative Example-1 and the conventional lotion of Comparative Example-2, respectively.
The subject was subjected to a usage test for 1 month. After use, the slimming effect was determined by a questionnaire survey on the firmness, tension and elasticity of the skin. As a result, the cosmetics characterized by containing the Chimpi extract, the tea extract, and the lotus meat extract showed excellent slimming effects (Table 2, Table 3, Table 4, Table 5, Table 6, Table 6). 7).

[0112]

[Table 2] Table 2 Slimming effect of skin lotion of the present invention (number of questionnaire results) ─────────────────────────────── ── Evaluation of lotion of the present invention (Example-3) ─────────────────────── Very good Good Normal ──────── ──────────────────────── Tightening of the skin 19 8 3 Tension of the skin 19 7 4 Elasticity of the skin 18 8 4 ────── ──────────────────────────

[0113]

[Table 3] Table 3 Slimming effect of lotion of the present invention (number of questionnaire results) ─────────────────────────────── ── Evaluation of lotion of the present invention (Example-4) ─────────────────────── Very good Good Normal ──────── ──────────────────────── Tightening of the skin 21 8 1 Tension of the skin 18 9 3 Elasticity of the skin 20 8 2 ────── ──────────────────────────

[0114]

[Table 4] Table 4 Slimming effect of conventional lotion (number of questionnaire results) ──────────────────────────────── ── Conventional lotion (Comparative example-1) ──────────────────────── Very good Good Normal ───────── ──────────────────────── Tightening of the skin 3 7 20 Tension of the skin 2 8 20 Elasticity of the skin 4 9 17 ────── ────────────────────────────

[0115]

[Table 5] Table 5 Slimming effect of the emulsion of the present invention (number of questionnaire results) ──────────────────────────────── -Emulsion of the present invention (Example-17) Evaluation ─────────────────────── Very good Good Normal ─────────── ────────────────────── Tightening of the skin 20 8 2 Tension of the skin 13 13 4 Elasticity of the skin 19 7 4 ───────── ──────────────────────── Margins below

[0116]

[Table 6] Table 6 Slimming effect of the emulsion of the present invention (number of questionnaire results) ──────────────────────────────── -Emulsion of the present invention (Example-18) Evaluation ─────────────────────── Very good Good Normal ─────────── ────────────────────── Skin tightness 16 11 3 Skin tension 17 9 4 Elasticity of skin 20 7 3 ──────── ────────────────────────

[0117]

[Table 7] Table 7 Slimming effect of conventional emulsion (number of people in the questionnaire result) ───────────────────────────────── Conventional emulsion (Comparative example-2) Evaluation ──────────────────────── Very good Good Normal ──────────── ───────────────────── Tightening of the skin 5 4 21 Tension of the skin 4 7 19 Elasticity of the skin 2 8 20 ───────── ─────────────────────── As shown above, ethanol extract of chimpi, hot tea extract of hot water, hot water extract of lotus root, ginseng The hot water extract, chamomile hot water extract and 1,3-butylene glycol extract of Sikon show excellent lipolytic activity, and the ethanolic extract, tea hot water extract and lotus hot water of chimp of the present invention. Distribute the extract The combined cosmetics and slimming agents showed excellent slimming effects. In addition, the same use test was carried out on cosmetics containing a hot water extract of ginseng, a hot water extract of chamomile, and a 1,3-butylene glycol extract of Sikon, and as a result, an excellent slimming effect was shown.

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Claims (2)

[Claims] 1. A slimming cosmetic composition containing one or more kinds of extracts selected from chimpi, tea, lotus meat, ginseng, chamomile and shikon. 2. A slimming agent containing one or more kinds of extracts selected from chimpi, tea, lotus meat, ginseng, chamomile and shikon.