JPH09208412A - Use of condensed phosphoric acid compound as bactericide or anti-mold agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject agent suitably used for a wide range of usage such as a coating material, an adhesive, etc., containing a specific polyphosphoric acid ammonium or modified material thereof having an extremely low toxicity to a human body and excellent bacteriocidal and anti-mold properties as an active ingredient. SOLUTION: This bacteriocidal and anti-mold agent comprises a polyphosphoric acid ammonium of formula I [(m+n) is >=3; (n) is >=1; R1 is NH4 ; R2 is NH4 , CONH2 , formula II (R3 is NH3 ; R4 , R5 are each NH2 , NHCONH2 , NHCH2 OH, an alkyl or phenyl)]. The polyphosphoric acid ammonium of the formula I is obtained e.g. by reacting ammonium phosphate with an approximately same mol of phosphoric anhydride at a high temperature. The particle size of polyphosphoric acid ammonium or modified material thereof is preferably <=50μm. The compound can be used for an adhesive, a sealant, a putty, a paper, a fabric, a fiber, various resins, a ceramic, etc., but in the case of requiring a water proof property, it is preferable to make >=1000 mean molecular weight thereof.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to the use of a condensed phosphoric acid compound as an antibacterial agent or antifungal agent. More specifically, it relates to the use of ammonium polyphosphate or a modified product thereof as an antibacterial agent or antifungal agent.

[0002]

2. Description of the Related Art A wide variety of bacteria and fungi are present in our living space. Especially in a hot and humid environment such as Japan, bacteria and fungi easily grow. As a result, the skin may be damaged, or the product may be deteriorated, discolored, deteriorated, or give off a bad odor to cause discomfort. In these circumstances, antibacterial and antifungal orientations have been increasing in recent years, and paints, adhesives,
In many applications such as adhesives, sealants, putties, papers, textiles, fibers, various resins, and ceramics, development of comfortable, hygienic and highly safe antibacterial agents and fungicides is desired.

Although there have been times when organotin and organomercury compounds were used as substances having high antibacterial and antifungal properties, most of them are now prohibited.

It has long been known that metals such as silver, copper and zinc have antibacterial and antifungal properties. Until now, silver, copper and zinc have been added to polymers to provide antibacterial and antifungal properties. Attempts to impart moldability have been made, for example, by Japanese Patent Application Laid-Open No. 54-147.
Many proposals have been made such as the 220 publication. In addition, an attempt to add zeolite-based solid particles ion-exchanged with silver ions and copper ions to a high molecular weight polymer is disclosed in, for example, JP-A-59-1.
It is proposed in Japanese Patent No. 33235.

These inorganic antibacterial agents and antifungal agents are superior in heat resistance, sustained release and sustainability to organic ones, can be kneaded into resins and the like, and can be used for medical purposes. It has a wide range of applicability to everyday items. However, since the metal and the metal ion are blended, there are problems that the resin is discolored and the use thereof is limited.

[0006]

DISCLOSURE OF THE INVENTION Problems to be Solved by the Invention
We have made extensive studies to solve the above problems. As a result, they have found that ammonium polyphosphate or a modified product thereof has extremely low toxicity to the human body and has excellent antibacterial and antifungal properties, and completed the present invention. As is clear from the above description, the object of the present invention can be suitably used for a wide range of applications such as paints, adhesives, adhesives, sealants, putties, papers, fabrics, fibers, various resins, and ceramics.
It is intended to provide a method for using ammonium polyphosphate or a modified product thereof as an antibacterial agent and an antifungal agent.

[0007]

The present invention has the following arrangement. (1) Use of a condensed phosphoric acid compound represented by the following chemical formula 3 as an antibacterial agent or antifungal agent.

Embedded image (In the formula, n + m ≧ 3, n ≧ 1, and R ₁ is NH ₄ , R ₂
Is NH ₄ , CONH ₂ or a mixture of one or more triazine compounds represented by the following chemical formula 4).

Embedded image (In the formula, R ₃ is NH ₃ , R ₄ and R ₅ are the same or different N
H ₂ , NHCONH ₂ , NHCH ₂ OH, an alkyl group or a phenyl group).

The details of the present invention will be described below. The ammonium polyphosphate used in the present invention is disclosed in, for example, Japanese Patent Application Laid-Open No.
As described in JP-A-6-024717, it can be obtained by reacting ammonium phosphate and phosphoric anhydride in approximately the same mole at high temperature. It is known that ammonium polyphosphate has crystal forms from I-type to V-type due to the difference in crystal type, but the present invention is not particularly limited to the crystal type. As the ammonium polyphosphate, for example, commercially available products such as Sumisafe P (trade name: manufactured by Sumitomo Chemical Co., Ltd.), Exolit-
422 (Product name: Hoechst), Foscheck (P
hos-chek) P / 40 (trade name: manufactured by Monsanto Co., Ltd.), TERRAJU S (trademark: manufactured by Chisso Corporation), and the like, and ammonium polyphosphate obtained by a known method. Can also be used.

The modified ammonium polyphosphate used in the present invention can be obtained by reacting ammonium polyphosphate with one or a mixture of two or more urea or triazine compounds. Examples of the triazine compound include acetoguanamine, benzoguanamine, melamine, methylolmelamine, and urea-added melamine. Examples of commercially available products of the modified ammonium polyphosphate include Sumisafe PM (trade name: manufactured by Sumitomo Chemical Co., Ltd.).

The particle size of ammonium polyphosphate or its modified product used in the present invention is not particularly limited, but is preferably 50 μm or less. When the particle size is larger than 50 μm, the dispersibility becomes poor when kneaded into various materials, resulting in product quality,
In particular, it causes a decrease in mechanical strength.

The ammonium polyphosphate or a modified product thereof used in the present invention can be suitably used in a wide variety of applications such as paints, adhesives, pressure-sensitive adhesives, sealants, putties, papers, fabrics, fibers, various resins, and ceramics. When used in applications requiring water resistance, such as paints, sealants, putties, and various resins, it is preferable that the average molecular weight of ammonium polyphosphate or its modified product is 1000 or more. If the average molecular weight is less than 1000, the water resistance may be extremely reduced.

Although the details of the antibacterial action or antifungal action of the ammonium polyphosphate or its modified product of the present invention are unknown, some bacteria may be added to the P, NH ₄ , triazine compounds, etc. possessed by the ammonium polyphosphate or its modified product. This is probably because it has an antiproliferative action and a fungal antiproliferative action.

[0013]

EXAMPLES In order to specifically describe the present invention, examples and comparative examples are shown below, but the present invention is not limited thereto.

Example 1 [Antibacterial test] Agar plate method: 15 ml of ordinary broth agar medium (1.5% by weight of agar) was added to E. coli culture solution (37 ° C).
100-fold diluted solution (shocked for 24 hours at room temperature)
(× 10 ⁷ cells / ml) were mixed in a deep petri dish to solidify. 2 to the resulting medium with sterile microspatels
A 3 mm hole was opened, 0.1 g of Terraju S (trade name: manufactured by Chisso Corporation) was added as ammonium polyphosphate, the Petri dish was covered with a lid, and the mixture was allowed to stand overnight at 37 ° C. to check the inhibition circle. did. As a result, a clear inhibition circle was observed, confirming the inhibition of bacterial growth.

Examples 2 to 7 In accordance with Example 1, tests were carried out using various modified products of ammonium polyphosphate. The results are shown in Table 1.

Comparative Example 1 A blank test was conducted in accordance with Example 1 except that ammonium polyphosphate was not added. The results are shown in Table 1.

[0017]

Industrial Applicability The ammonium polyphosphate or a modified product thereof of the present invention has excellent antibacterial and antifungal properties, is low in toxicity, and is excellent in heat resistance and water resistance. It can be used as an antibacterial or antifungal agent in a wide range of applications such as adhesives, sealants, putties, papers, fabrics, fibers, various resins, and ceramics.

[0018]

[Table 1]

Claims (1)

[Claims] 1. Use of a condensed phosphoric acid compound represented by the following chemical formula 1 as an antibacterial agent or antifungal agent. Embedded image (In the formula, n + m ≧ 3, n ≧ 1, and R ₁ is NH ₄ , R ₂
Is NH ₄ , CONH ₂ or a mixture of one or more triazine compounds represented by the following chemical formula 2). Embedded image (In the formula, R ₃ is NH ₃ , and R ₄ and R ₅ are the same or different NH ₂ , NHCONH ₂ , NHCH ₂ OH, an alkyl group or a phenyl group).