JP2006052209A - Fungicide, antimicrobial agent and deodorizing agent and fungicidal, antimicrobial and deodorizing method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To attain safety, environmental compatibility, persistency of effect, prevention, etc., of occurrence of resistant bacteria and prevent wide kinds of fungi and prevent organic change. <P>SOLUTION: The fungicide, the antimicrobial agent and the deodorizing agent are each obtained by adding 1 to 10 mass% antimicrobial composition obtained by adding two or more kinds of antimicrobial agents selected from nitrile-based antimicrobial agents, pyridine-based antimicrobial agents, haloalkylthio-based antimicrobial agents, organic iodide-based antimicrobial agents, isothiazolyl-based antimicrobial agents and thiazole-based antimicrobial agents each in amounts of 0.1 to 40 mass% to a deodorizing composition containing a titanium phosphate-based compound represented by the chemical formula: Ti(OH)<SB>x</SB>(PO<SB>4</SB>)<SB>y</SB>(HPO<SB>4</SB>)<SB>z</SB>(H<SB>2</SB>PO<SB>4</SB>)<SB>m</SB>(OR)<SB>n</SB>(R is a 1-4C alkyl group; x, y, z, m and n are each a value of ≥0 and satisfies the formula x+3y+2z+m+n=4) or its condensation product as an active ingredient. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  This invention achieves safety, environmental compatibility, long-lasting effects, prevention of resistant bacteria, etc., has a barrier effect, can prevent a wide variety of sputum, and hardly causes organic changes. The present invention relates to an antifungal agent, an antibacterial agent and a deodorizing agent, and an antifungal, antibacterial and deodorizing method.

  Prior to the filing of this invention, an antibacterial agent, deodorant and antifungal agent which are environmentally friendly and do not affect the human body, and an antibacterial, deodorant or antifungal method have been proposed.

The proposed invention has the _{formula: Ti (OH) x (PO} 4) y (HPO 4) z (H 2 PO 4) l (OR) m (R is an alkyl group having 1 to 4 carbon atoms, x, y , Z, 1 and m are each a numerical value of 0 or more and satisfy x + 3y + 2z + 1 + m = 4.) An antibacterial agent, a deodorant and an antifungal agent containing a titanium phosphate compound represented by A method of spraying or applying these. The titanium phosphate compound is obtained by reacting titanium tetrachloride with water, an alcohol having 1 to 4 carbon atoms, or a mixed solution thereof, and further reacting with phosphoric acid.
JP-A-14-308712

  The invention of Patent Document 1 can be used as an antibacterial / deodorant solution diluted with a solvent such as water or alcohol, and is suitable for spraying, but has poor storage stability. During storage, solid matter was precipitated and turbidity was generated, which could clog the spray nozzle, and there was a problem that the antifungal and antibacterial effects were not sufficient.

  The present invention prevents the precipitation of solids over time by adding at least one of a titanium silicate compound and a titanium borate compound to the invention of Patent Document 1, and a nitrile antibacterial agent and a pyridine antibacterial agent Including haloalkylthio antibacterial agents, benzimidazole antibacterial agents, organic iodine antibacterial agents and thiazole antibacterial agents as active ingredients, we have succeeded in dramatically improving antifungal, antibacterial and deodorizing effects. The above problems have been solved.

That the present invention, the chemical formula _{Ti (OH) x (PO 4} ) y (HPO 4) z (H 2 PO 4) m (OR) n
(R is an alkyl group having 1 to 4 carbon atoms, x, y, z, m, and n are numerical values of 0 or more, respectively, and satisfy x + 3y + z + m + n = 4.)
Deodorant composition containing a titanium phosphate compound represented by the above or a condensate thereof as an active ingredient, nitrile antibacterial agent, pyridine antibacterial agent, haloalkylthio antibacterial agent, benzimidazole antibacterial agent, organic iodine antibacterial agent An antifungal agent comprising 1% by mass to 10% by mass of an antibacterial composition obtained by adding 0.1% by mass to 40% by mass of an antibacterial agent, an isothiazolyl antibacterial agent and a thiazole antibacterial agent. , Antibacterial agents and deodorants.

In another invention, the chemical formula is Ti (OH) _x (PO ₄ ) _y (HPO ₄ ) _z (H ₂ PO ₄ ) _m (OR) _n.
(R is an alkyl group having 1 to 4 carbon atoms, x, y, z, m, and n are each a number of 0 or more, and satisfy x + 3y + 2z + m + n = 4.)
A 2-pyridinethiol-1-oxide containing a titanium phosphate compound or a condensate thereof, and at least one of a titanium silicate compound and a titanium borate compound. Sodium, 2,3,5,6-tetrachloro-4-methylsulfonylpyridine, 2- (n-octyl) -4-isothiazolin-3-one, diiodomethyl-P-tolyl-sulfone, methyl (benzimidazole- 1 to 10% by mass of an antibacterial composition obtained by adding 0.1% to 40% by mass of 2-yl) carbamate and 1,2benzisothiazolin-3-one, respectively. And antifungal agents, antibacterial agents and deodorants.

  Another invention is an antifungal, antibacterial and deodorizing method characterized in that the antifungal agent, antibacterial agent and deodorant according to claim 1 or 2 are sprayed or applied.

According to the invention, the storage stability and spray utilization are improved, as well as antifungal, antibacterial,
It is recognized that the deodorizing effect is also greatly improved. In addition, when sprayed, the coating property is good, and thus a stable effect can be exhibited over a long period of time.

  With respect to the above-mentioned invention, improvement of antifungal, antibacterial and deodorizing effects is recognized.

Next, it was confirmed that the composition of this invention is effective against various bacteria as shown in Tables 1 to 18. Heretofore, compositions effective for such a large number of fungi or algae have not been known.

  The composition of the antibacterial / deodorant used in this invention is composed of a titanium phosphate compound or a condensate thereof (hereinafter referred to only as a titanium phosphate compound), a titanium silicate compound and boric acid. A component selected from titanium compounds is contained as an active ingredient.

  On the other hand, a titanium silicate compound and a titanium borate compound are effective components for deodorization, and both the titanium silicate compound and the titanium borate compound can be used in combination with either one.

  Further, the titanium borate compound can be produced using boric acid and titanium tetrachloride as main raw materials. First, boric acid is dissolved in water or alcohol or a mixed solution of water and alcohol. As the alcohol, it is preferable to use an aliphatic alcohol having 1 to 4 carbon atoms, and isopropyl alcohol is most preferable. When a mixed solution of water and alcohol is used, the mixing ratio is not particularly limited, but is preferably in a range of 30% to 70% water and 70% to 30% alcohol by volume ratio. The amount of boric acid added to water or alcohol is preferably in the range of 0.01 to 30 parts boric acid with respect to 100 parts water or alcohol in volume ratio. If the amount of boric acid is less than 0.01 part, the deodorizing activity is low and a sufficient deodorizing effect cannot be obtained. On the other hand, when the amount of boric acid exceeds 30 parts, a cloudy state is likely to occur.

Next, titanium tetrachloride is added to the boric acid solution thus obtained for reaction. The amount of titanium tetrachloride added is preferably in the range of 8 to 100 parts by volume with respect to 100 parts of the reaction solution. If the amount of titanium tetrachloride is less than 8 parts, the deodorizing activity is low and a sufficient deodorizing effect cannot be obtained. Moreover, when there is too much quantity of titanium tetrachloride, since the film-forming state of the coating film formed by spray application will worsen and it will become easy to peel, 100 parts or less are preferable and 50 parts or less are more preferable. When titanium tetrachloride is added to the boric acid solution as described above, a reaction immediately occurs at room temperature to produce a titanium borate compound, an aqueous solution or an alcohol solution of the titanium borate compound, or a mixture of water and alcohol. A solution in which a titanium borate compound is dissolved in the solution can be obtained. The produced titanium borate compound is a compound having a chemical composition of TiO ₂ · B ₂ O ₃ according to the analysis result.

  To the titanium phosphate compound solution obtained as described above, at least one of a titanium silicate compound solution and a titanium borate compound solution is added and mixed to form a nitrile antibacterial agent, pyridine Antibacterial agent, haloalkylthio antibacterial agent, benzimidazole antibacterial agent, organic iodine antibacterial agent, isothiazolyl antibacterial agent and thiazole antibacterial agent added in an amount of 0.1% by mass to 40% by mass, respectively. An antifungal / antibacterial / deodorant according to the present invention can be obtained by adding 1% by mass to 10% by mass of the composition.

  This invention has the following special effects not found in other drugs.

1. Barrier effect Unlike other antibacterial agents and fungicides that destroy bacteria and fungi (cells) from the cell wall to DNA (nuclei) and sterilize them, the composition of the present invention destroys only the cell walls and prevents protein and DNA ( Inhibits the synthesis of nuclei).

  Therefore, the bacteria whose synthesis has been inhibited cannot obtain the nutrients necessary for growth and die themselves. At that time, since the danger information is transmitted to the homologous bacteria, the composition of the present invention exhibits a repellent effect against the killed homologous bacteria and forms a blocking zone (barrier) in the transmission range.

  2. 406 types and a wide range of antibacterial spectrum (Tables 1 to 18).

  We conducted an effect test on 406 types of micro-, bacteria- and algae, including “57 bacteria detected at high frequency from general buildings” confirmed by the World Disaster Microbiology Academy, and the effect on each individual fungus Possess antibacterial spectrum. Accordingly, there is no effect comparable to the composition of the present invention in terms of effects on cocoons, bacteria, and algae, and it is outstanding.

  3. Emphasis on safety.

  The safety of the composition of the present invention has been confirmed in various tests. Further, since the composition of the present invention hardly evaporates and evaporates, there is no risk of causing Suminohara disease or allergy.

  Tests at the Japan Food Analysis Center prove that the drugs do not contain dioxins and do not use any chemical substances listed as environmental hormones. However, it is an antibacterial, antifungal and antialgal agent unlike any other.

  4). There is persistence of effect.

Conventional antifungal agents exert their effects by elution and vaporization, so the effect was not sustained as much as there was much moisture. In addition, when the residual concentration of the drug decreased, the strong fertility mold that had been antagonistic until then increased rapidly, and the damage caused by drought was often worse than before the drug was used. As shown in Table 19 and Table 20, the composition used in the present invention is characterized by a longer effective period than other drugs.

  This is because, unlike other drugs, it is an elution type drug with less elution and vaporization of components, and the effect and sustainability of the composition of the present invention is a harsh environment that was difficult to suppress with conventional drugs. It stands out.

  5. Bacterial resistance is not born.

  The composition of the present invention employs a delayed-repellent repellency-type composite synthetic agent, so that sputum and bacteria naturally die (attack of soldiers) over 48 to 72 hours (2 to 3 days). For this reason, resistant bacteria are not born like the bactericides killed. Moreover, since it is a complex synthetic agent, unlike a single drug, even if it becomes one resistant bacterium, other drugs are effective, and from this aspect, it is a drug that hardly causes resistant bacteria. Therefore, there is no case where the previous product becomes ineffective and an improved product must be produced.

  6). Does not cause organic changes.

  The composition of the present invention has a stability that is not decomposed by heat, ultraviolet rays, acids, alkalis, organic solvents, and the like.

The invention of the antibacterial / deodorant is to mix titanium tetrachloride with a mixture of isopropyl alcohol and purified water while stirring at room temperature to react, dilute the reaction solution with purified water, and then add aqueous phosphoric acid solution. the by reacting in _addition, could _{Ti (OH) x (PO4)} y (HPO 4) z (H 2 PO 4) m (OCH (CH 3) 2) titanium phosphate compound of _n.

  On the other hand, silicon tetrachloride was added to a mixed solution of isopropyl alcohol and purified water and allowed to react indoors. Titanium tetrachloride was added to this reaction solution and reacted at room temperature to obtain a titanium silicate compound solution.

  The antibacterial and deodorant composition obtained by mixing the titanium silicate compound solution with the titanium phosphate compound solution and diluting with purified water is added to the nitrile antibacterial agent, pyridine antibacterial agent, and haloalkylthio type. Antibacterial, antifungal, and antialgal antibacterial agents, benzimidazole antibacterial agents, organic iodine antibacterial agents, isothiazolyl antibacterial agents and thiazole antibacterial agents added in an amount of 0.1% to 40% by mass, The antibacterial composition, the antibacterial agent and the deodorant of the present invention were obtained by adding 1% by mass to 4% by mass of the antibacterial composition.

To illustrate embodiments of the present invention, titanium phosphate compound is an antibacterial, an active ingredient of deodorizing and antifungal, chemical formula _{Ti (OH) x (PO 4} ) y (HPO 4) z (H 2 PO 4 ) _M (OR) _n
(R is an alkyl group having 1 to 4 carbon atoms, x, y, z, m, and n are each a number of 0 or more, and satisfy x + 3y + 2z + m + n = 4.)
It is represented by If the carbon number of R is too small, the viscosity of the antibacterial / deodorant solution will be low, the film thickness will be thin when sprayed to form a film, and the antibacterial, deodorant or antifungal effect will tend to be low. is there. On the other hand, if the number of carbons is too large, the viscosity of the antibacterial / deodorant solution increases and the film thickness tends to increase, and the film tends to peel off when formed. R is preferably an ethyl group or an isopropyl group.

Examples of the titanium phosphate compound include Ti (OH) (H ₂ PO ₄ ) ₂ (OR), Ti (OH) (PO ₄ ), Ti (OH) ₂ (H ₂ PO ₄ ) (OR), Ti (OH) (HPO ₄ ) (OR), Ti (OH) (HPO ₄ ) (H ₂ PO ₄ ), Ti (OH) ₂ (H ₂ PO ₄ ) ₂ , Ti (OH) ₃ (H ₂ PO ₄ ), Ti (OH) ₃ (OR) and the like are preferable.

  In producing the titanium phosphate compound, first, titanium tetrachloride is reacted with water, an alcohol having 1 to 4 carbon atoms, or a mixed solution thereof. When using the mixed solution of water and alcohol, it is preferable that water is 30-70 volume%. The addition amount of titanium tetrachloride is preferably in the range of 0.01 to 30 parts by volume with respect to 100 parts of water or alcohol or mixed solution. The reaction temperature between titanium tetrachloride and water or alcohol may be room temperature, for example, 5 to 35 ° C. The relative humidity when mixing titanium tetrachloride with water or alcohol is preferably 10% to 80%, particularly preferably 20% to 60%. When the relative humidity exceeds 80%, a large amount of yellow powder of titanium tetrachloride is generated, and its particle size increases and the activity tends to decrease. On the other hand, if it is less than 10%, white powder is formed, and there is a tendency that film hardness and sustainability of the activity are problematic. The pH of the reaction solution at the end of the reaction is usually about 1.

Next, after diluting the reaction solution thus obtained with a solvent such as water or alcohol in the range of 10 to 500 times, phosphoric acid is added and reacted. If the dilution is less than 10 times, even if a small amount of phosphoric acid is added, it tends to become cloudy. Since white solids are deposited in the cloudy liquid, there is a risk of clogging the spray nozzle, and white powder appears on the surface of the sprayed film, and the film hardness decreases, causing peeling and dropping, and sustainability. Problems arise. The addition amount of phosphoric acid is preferably in the range of 8 to 500 parts by volume with respect to 100 parts of the reaction solution. If it exceeds 500 parts, the solution tends to become cloudy, and it is preferably 450 parts or less, particularly preferably 400 parts or less. When phosphoric acid is added to the reaction solution in this way, a reaction immediately occurs at room temperature to produce a titanium phosphate compound, and an aqueous solution or alcohol solution of the titanium phosphate compound, or a mixed solution of water and alcohol is phosphoric acid. A solution in which a titanium compound is dissolved can be obtained.

  5% by mass of a composition containing nitrile antibacterial agent and haloalkylthio antibacterial agent as active ingredients in the solution, 11% by mass of sodium 2-pyridinethiol-1-oxide, 2,3,5,6-tetrachloro- 4-methylsulfonylpyridine 16% by mass, 2- (n-octyl) -4-isothiazolin-3-one 16% by mass, diiodomethyl-P-tolyl-sulphone 16% by mass, methyl (benzimidazol-2-yl) When 2% by mass of a composition obtained by mixing 16% by mass of carbamate and 20% by mass of 1,2-benzisothiazolin-3-one was added, the antifungal agent, antibacterial agent and deodorant of this invention were obtained.

  Describing an embodiment of the present invention, a titanium silicate compound can be produced using silicon tetrachloride and titanium tetrachloride as main raw materials. First, silicon tetrachloride is water or alcohol, or water and alcohol. React with mixed solution. As the alcohol, an aliphatic alcohol having 1 to 4 carbon atoms is preferably used, and isopropyl alcohol is most preferable. When using the mixed solution of water and alcohol, the range of 30-70% water and 70% -30% alcohol is preferable by volume ratio. The amount of silicon tetrachloride added to water or alcohol is preferably in the range of 0.01 to 30 parts by volume with respect to 100 parts of water or alcohol. If the amount of silicon tetrachloride is less than 0.01 part, the deodorizing activity is low and a sufficient deodorizing effect cannot be obtained. On the other hand, when the amount of silicon tetrachloride exceeds 30 parts, a cloudy state is likely to occur. It is desirable that the relative humidity of the atmosphere when adding silicon tetrachloride to water or alcohol to react is 10 to 80%, particularly 20 to 60%. When the relative humidity exceeds 80%, a yellow powder of silicon tetrachloride is produced, the particle size thereof is increased, and the deodorizing activity tends to be reduced. If the relative humidity is less than 10%, a white powder of silicon tetrachloride may be formed. The above reaction can be performed at room temperature. When silicon tetrachloride is added to water or alcohol, the reaction occurs immediately, and the pH of the solution becomes about 1.

Next, titanium tetrachloride is added to the reaction solution thus obtained and reacted. The amount of titanium tetrachloride added is preferably in the range of 8 to 100 parts by volume with respect to 100 parts of the reaction solution. If the amount of titanium tetrachloride is less than 8 parts, the deodorizing activity is low and a sufficient deodorizing effect cannot be obtained. Moreover, when there is too much quantity of titanium tetrachloride, since the film-forming state of the coating film formed by spray application will worsen and it will become easy to peel, 100 parts or less are preferable and 50 parts or less are more preferable. When titanium tetrachloride is added to the above reaction solution in this way, a reaction immediately occurs at room temperature, and a titanium silicate compound is formed, and the aqueous solution or alcohol solution of the titanium silicate compound or the mixed solution of water and alcohol is used. A solution in which the titanium acid compound is dissolved can be obtained. The generated titanium silicate compound is a compound having a chemical composition of TiO ₂ · SiO ₂ according to the analysis result.

  5% by mass of a composition containing nitrile antibacterial agent and haloalkylthio antibacterial agent as active ingredients in the solution, 11% by mass of sodium 2-pyridinethiol-1-oxide, 2,3,5,6-tetrachloro- 4-methylsulfonylpyridine 16% by mass, 2- (n-octyl) -4-isothiazolin-3-one 16% by mass, diiodomethyl-P-tolyl-sulphone 16% by mass, methyl (benzimidazol-2-yl) When 2% by mass of a composition obtained by mixing 16% by mass of carbamate and 20% by mass of 1,2-benzisothiazolin-3-one was added, the antifungal agent, antibacterial agent and deodorant of this invention were obtained.

An antibacterial and deodorizing method using a titanium phosphate compound according to an embodiment of the present invention will be described. A mixture of 25 ml of isopropyl alcohol and 25 ml of purified water is mixed with 5 ml of titanium tetrachloride with stirring, and then purified with purified water. Diluted twice. To this, 5 ml of 85% phosphoric acid aqueous solution was added to obtain approximately 5.5 l of a titanium phosphate compound. The titanium phosphate _compound, is estimated to _{Ti (OH) x (PO 4} ) y (HPO 4) z (H 2 PO 4) l (OCH (CH 3) 2) m or it is a composition which is fused .

On the other hand, 30 g of silicon tetrachloride was added to a mixed solution of 100 ml of purified water and 100 ml of isopropyl alcohol, and reacted at room temperature. Next, 50 g of titanium tetrachloride was added to the reaction solution and reacted at room temperature to obtain approximately 300 ml of a titanium silicate compound solution. The obtained titanium silicate compound was presumed to have a chemical composition of TiO ₂ · SiO ₂ .

  Then, 100 parts by volume of the titanium phosphate compound solution obtained as described above and 10 parts by volume of the titanium silicate compound solution are mixed, and further diluted 10 times with purified water as an antibacterial / deodorant. Prepared. 5% by mass of a composition containing nitrile antibacterial agent and haloalkylthio antibacterial agent as active ingredients, 11% by mass of sodium 2-pyridinethiol-1-oxide, 2, 3, 5, 6-tetrachloro-4-methylsulfonylpyridine 16% by mass, 2- (n-octyl) -4-isothiazolin-3-one 16% by mass, diiodomethyl-P-tolyl-sulfone 16% by mass, methyl (benzimidazole) 2-yl) carbamate 16% by mass and 1,2benzisothiazolin-3-one 2% by mass obtained by mixing 20% by mass, the antifungal agent, antibacterial agent and deodorant of this invention An agent was obtained.

Explaining an embodiment of the present invention, a mixed solution of 25 ml of isopropyl alcohol and 25 ml of purified water was mixed and reacted with 5 ml of titanium tetrachloride while stirring at room temperature, and this reaction solution was diluted 100 times with purified water. . Next, a solution of a titanium phosphate-based compound was obtained by adding 5 ml of an 85 mass% phosphoric acid aqueous solution to the reaction. As a result of analysis, the obtained titanium phosphate compound has a chemical composition of Ti (OH) _x (PO ₄ ) _y (HPO ₄ ) _z (H ₂ PO ₄ ) _m (OCH (CH ₃ ) ₂ ) _n or It was estimated to be a condensed chemical composition.

On the other hand, 30 g of silicon tetrachloride was added to a mixed solution of 100 ml of purified water and 100 ml of isopropyl alcohol, and reacted at room temperature. Next, 50 g of titanium tetrachloride was added to the reaction solution and reacted at room temperature to obtain approximately 300 ml of a titanium silicate compound solution. The obtained titanium silicate compound was presumed to have a chemical composition of TiO ₂ · SiO ₂ .

  100 parts by volume of the titanium phosphate compound solution obtained as described above and 10 parts by volume of the titanium silicate compound solution were mixed and further diluted 10 times with purified water to obtain an antibacterial and deodorant composition.

  10% by mass of a composition containing a nitrile antibacterial agent and a haloalkylthio antibacterial agent as active ingredients in the composition, 10% by mass of sodium 2-pyridinethiol-1-oxide, 2,3,5,6-tetrachloro 16% by mass of -4-methylsulfonylpyridine, 16% by mass of 2- (n-octyl) -4-isothiazolin-3-one, 18% by mass of diiodomethyl-P-tolyl-sulfone, methyl (benzimidazol-2-yl) ) When 4% by mass of a composition obtained by mixing 30% by mass of carbamate was added, the antifungal agent, antibacterial agent and deodorant of this invention were obtained.

[Effectiveness test]
The effect test of the present invention is as follows.

  The mold prevention test MIL STD 810 DMethod 508-3 modified method was employed, and the following 60 kinds of mixed molds were used. Inoculated directly from the mixed spore suspension of the test bacteria by wet method, with potato dextrose agar medium (without adding antibiotics such as PDA and chloramphenicol), temperature 30 ± 5 ° C, humidity 95% ± 15% RH, wind speed The cells were cultured for 28 days at 60 cm / sec. Evaluation was made according to the following five levels.

0 ... No fungal growth at all.

1 ... There is a slight growth of mold.

2 ... There is a little growth of mold.

3 ... There is considerable growth of mold.

4 ... Mold growth is intense.

  The fungi used were the following fungi. Acremonium Chalticola, Aspergillus oryzae, Aspergillus candidas, Aspergillus niger, Aspergillus fumigatus, Aspergillus ferricor, Aspergillus flavus, Alternaria alternata, Alternaria tenor, prácula olci , Calbalaria lunata, Candita albicans, Cladosporium, Cladosporiaidas, Cladosporia saphaerosperma, Cladosporum herbalem, Cladosporum resine, Geotricum candidam, Geotricam lactus, Ketomium globosum, Trichoderma Koninghi Biridi, Trichoftton Mentagrophytes, Dressilla Ostraline, Nigrospora Oryzae, Neurospora Gitofira, Former Glomerata, Forma Tereschias, Fusarium oxysporum, Fusarium Semitectum, Fusarium Solani, Fusarium Moniliforme, Fusarium Rosepura Audare Penicillium islandicam, Penicillium icpansa, Penicillium cyclopium, Penicillium citrinum, Penicillium citreability, Penicillium niglycans, Penicillium funiculosum, Penicillium flectus, Penicillium lyracinam, Potritis cinerea, Milotesium ferr Kalia, Mucor Spinense, Mucor Racemasus, Moniria Fructigana, Eurotium Amsterodami, Eurotium Sybareri, Eurotium Tonafilum, Eurotium Rubram, Rhizopus Oryzae, Rhizopus Stronifel, Rhizopus nigricans, Valemia Cevi. These fungi were stock culture pure cultures or subcultures within 30 days, each stored at 6 ° C. ± 4 ° C.

As a result of the above test, Table 21 was obtained.

The conditions of the composition in the test are as shown in Table 22.

Claims (3)

The chemical formula is Ti (OH) _x (PO ₄ ) _y (HPO ₄ ) _z (H ₂ PO ₄ ) _m (OR) _n
(R is an alkyl group having 1 to 4 carbon atoms, x, y, z, m, and n are numerical values of 0 or more, respectively, and satisfy x + 3y + z + m + n = 4.)
An antifungal agent, an antibacterial agent, and an antibacterial agent characterized by adding 1% by mass to 10% by mass of the following antibacterial composition to an odor eliminating composition comprising a titanium phosphate compound represented by Deodorants.
0.1% to 40% by mass of two or more of nitrile antibacterial agent, pyridine antibacterial agent, haloalkylthio antibacterial agent, benzimidazole antibacterial agent, organic iodine antibacterial agent, isothiazolyl antibacterial agent and thiazole antibacterial agent % Antibacterial composition each added. The chemical formula is Ti (OH) _x (PO ₄ ) _y (HPO ₄ ) _z (H ₂ PO ₄ ) _m (OR) _n
(R is an alkyl group having 1 to 4 carbon atoms, x, y, z, m, and n are each a number of 0 or more, and satisfy x + 3y + 2z + m + n = 4.)
The antibacterial composition 1% by mass to the deodorant composition comprising a titanium phosphate compound represented by the formula (1) or a condensate thereof, and at least one of a titanium silicate compound and a titanium borate compound. An antifungal agent, antibacterial agent and deodorant characterized by adding 10% by mass.
2-pyridinethiol-1-oxide sodium, 2,3,5,6-tetrachloro-4-methylsulfonylpyridine, 2- (n-octyl) -4-isothiazolin-3-one, diiodomethyl-P-tolyl -Antibacterial composition which adds 0.1 mass%-40 mass% of 2 or more types of sulfone, methyl (benzimidazol-2-yl) carbamate, and 1,2 benziso thiazolin-3-one, respectively.   An antifungal, antibacterial and deodorizing method comprising spraying or applying the antifungal agent, antibacterial agent and deodorant according to claim 1 or 2.