JPH0854342A - Device for inspecting amount of medicine applied to internal surface of blood collecting tube - Google Patents

Abstract

PURPOSE:To judge the propriety of the amount of a medicine for inspection applied to the internal surface of blood collecting tubes at a high speed under the same optical condition. CONSTITUTION:The device for inspecting amount of medicine applied to internal surface of blood collecting tube is constituted of a light source which lights an area equal to the area of one blood collecting tube 2 from the bottom side of a rack 8 mounting blood collecting tubes, a CCD camera 1 which takes the picture of the internal surface of each blood collecting tube from a position immediately above the tube, and a picture processor 5 which judge the propriety of the amount of a medicine applied to the internal surface of the tube by binarizing the data taken with the camera 1 after A/D conversion, counting the number of blackened areas which are medicine-applied areas, and comparing the count value with a reference count value.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an inspection apparatus for determining whether the amount of a drug applied to the inner wall surface of a blood collection tube used for medical inspection is good or bad.

[0002]

2. Description of the Related Art Conventionally, when a drug is applied to the inner wall surface of a blood collection tube, for example, as described in JP-A-2-167140, an aqueous solution or water dispersion of the drug is sprayed by an airless spray or the like, An aqueous solution or aqueous dispersion of the drug was adhered to the predetermined position on the inner wall surface of the blood collection tube in the form of water droplets having a fine particle diameter, and the adhered amount was controlled by the atomization time of the spray. In this case, as a method of determining the quality of the application amount of the drug applied to the inner wall surface of each of the many blood collection tubes inserted in the rack, in the case of a small scale, it is often due to human eyesight. On the other hand, in the case of automation, illumination is performed from the bottom of the rack with a surface light source that illuminates the entire bottom surface of the rack, and the area of the drug application part that looks black in the image taken by the camera from directly above the blood collection tube is obtained, The quality of the applied amount was determined.

[0003]

However, in the above method, since the illumination is applied to the portion other than the blood collection tube to be inspected, the blood collection tube taken by the diffuse reflection or wraparound of the light is taken. Each image often lacked quantification. In addition, generally, the shape and structure of the blood collection tube for mounting a plurality of blood collection tubes are not the same, and in addition, the surrounding conditions where the blood collection tube is installed during the inspection are often different each time, and measurement errors are likely to occur. It was in a state. For this reason, it is difficult to constantly illuminate all the blood collection tubes that require inspection with uniform illumination, and the images taken by the camera from directly above the blood collection tubes may vary.

The present invention has been made in order to solve the above-mentioned problems, and a uniform collection of illumination is applied to a blood collection tube whose inner wall surface needs to be inspected and a drug is applied to the blood collection tube from directly above the blood collection tube. It is an object of the present invention to provide an inspection device that determines whether or not the amount of a drug applied on the inner surface of a blood collection tube is inexpensive, is easy to handle, and does not cause variations in images taken by a camera.

[0005]

SUMMARY OF THE INVENTION In order to solve the above-mentioned problems, a blood collection tube inner surface drug application amount inspection apparatus of the present invention has a predetermined height position on the inner peripheral surface of a straight tube portion of a blood collection tube inserted in a rack. , A drug spray tube is inserted, and the drug is spray-applied from the spray tube to a predetermined height position on the inner peripheral surface of the straight tube portion of the blood collection tube, and then the drug applied to the inner peripheral surface of the blood collection tube An inspection device for determining whether the amount of coating is good, which is a moving device for moving a blood collection tube to be inspected inserted in a rack to an inspection position, and a blood collection tube to be inspected from below the rack in which the blood collection tube is inserted. A surface light source 7 for illuminating one area, and a CCD for taking an image of the inner surface of the blood collection tube from directly above the blood collection tube.
A camera 1, an A / D converter 4 for A / D converting an output signal of an image captured by the CCD camera, and a binarization process for the image signal converted by the A / D converter The inside of the blood collection tube is obtained by counting the number of blackened areas, which are the drug application parts, in the photographed internal image of the blood collection tube with a CCD camera and comparing the count value of the blackened area with a predetermined reference value. An image processing device 5 for determining whether the amount of the applied medicine is good or not, and an apparatus for inspecting the applied amount of the medicine on the inner surface of the blood collection tube.

Then, the blood collection tubes to be inspected are sequentially held one by one by the robot device while being held in the rack.
, And irradiated with the same light source, and all blood collection tubes will be sequentially examined under exactly the same optical environment.

[0007]

According to the present invention, when the amount of applied medicine is determined, the illumination applied to each blood collection tube held in the rack is performed by the same illumination device. The measurement conditions around the blood collection tube to be inspected are uniform without being affected by. Therefore, the variation in the value when measuring the drug application area is reduced, and the accuracy of the quality determination is improved.

[0008]

An embodiment of the present invention will be described with reference to the drawings.
FIG. 1 is an explanatory view showing an example of a blood collection tube inner surface drug application amount inspection device of the present invention. In the figure, 1 is a CCD camera, 2 is a blood collection tube, 4 is an A / D converter for A / D converting the signal from the CCD camera, 5 is a quality determination device, and 8 Is a rack for holding blood collection tubes, 7
Is a lighting device. Further, 6 is a light shielding plate, and the illumination device 7 irradiates an area of one blood collection tube.

In the above-described inspection apparatus, the blood collection tube 2 having the inner surface coated with the drug 3 is illuminated from the lower surface thereof by the illumination device 7, and the inner surface state of the blood collection tube is measured from directly above the CCD camera 1.
In the image photographed in (2), the part where the drug is not applied to the inner surface of the straight tube portion is white, and the part where the drug is applied to the inner surface is black.

Therefore, an image photographed from directly above the blood collection tube is observed as a black ring drawn on a white background, and the area of the black ring is proportional to the drug application amount.

The image photographed by the CCD camera is input to the image processing device 5 and binarized by using a predetermined reference value as a threshold value.

Further, the image processing apparatus 5 automatically sets the inspection range of the binarized image and measures the area of the drug applying portion within the range. That is, of the images captured by the CCD camera, the area determined to be a black portion as a result of being binarized by the image processing device 5 is counted from the number of pixels of the CCD camera. Then, after that, the image processing device 5
Determines whether the amount of drug applied to the inner surface of the blood collection tube is good or not, and ends the inspection.

As a method for applying the drug to the inner surface of the blood collection tube, the stopper of the blood collection tube is opened, and an aqueous dispersion of the drug or an aqueous solution of the drug is sprayed by a spray tube such as a spray. At this time, when the drug-applied portion on the inner surface of the blood collection tube is enlarged and seen, black particles are visible on the wall of the blood-collection-tube inner wall drug-applied portion, and a state in which white and black are mixed is observed. By observing the state of the enlarged drug application part, it is possible to contribute to the determination of the coarseness of the drug in the drug application part when there are many white parts and the denseness of the drug when there are many black parts. It is possible.

Therefore, by observing the state of the drug application portion on the inner surface of the blood collection tube, it is experimentally judged whether the drug application state is rough or dense before starting the drug application to all the blood collection tubes.
The drug concentration, application area, spraying time, etc. are adjusted so that the appropriate drug application amount is obtained.

The CCD camera uses an element of 490 × 570 pixels, but it is also effective to increase the discrimination speed by using an element of a small number of pixels. Also, one CC
It is also possible to simultaneously discriminate a plurality of blood collection tubes with the D camera.

The illuminating device uses a 22 mm × 22 mm surface light source for one blood collection tube, but a light source having an area larger than the diameter of the blood collection tube is preferable. Also, the same effect was obtained by using the method of irradiating the diffuser plate having the same area with the light of the spot light source.

For the illumination, the type of light source, the brightness, the size, the angle of illumination, the color of light, etc. can be freely selected according to the type, amount of application, color, etc. of the medicine.

After the quality determination according to the present invention is performed on the first blood collection tube as described above, the robot hand is made to grip the rack on which the blood collection tube is mounted, and the blood collection tube to be inspected next is set at the photographing position of the camera. To move. By repeating this operation sequentially and making a pass / fail judgment for all the blood collection tubes on the rack, a stable inspection can be performed under the same conditions.

[0019]

Since the configuration of the drug collection amount inspecting device for the inner surface of the blood collection tube of the present invention is as described above, all the blood collection tubes mounted on the rack are inspected by the same light source, and the surrounding light environment is affected. Therefore, it is possible to realize a simple and highly accurate and inexpensive internal-drug-injection-drug-inspection-apparatus inspection apparatus that can perform inspection with stable accuracy without being performed.

[0020]

[Brief description of drawings]

FIG. 1 is a diagram showing the configuration of a blood collection tube inner surface drug application amount inspection device of the present invention.

FIG. 2 is a diagram showing a flow of inspection of the present invention.

FIG. 3 is a diagram showing optical conditions of the present invention.

FIG. 4 is a diagram showing optical conditions of a conventional example. 1 CCD camera 2 Blood collection tube 3 Drug 4 A / D converter 5 Pass / fail judgment device 6 Light-shielding plate 7 Illumination device 8 Rack

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Claims (1)

[Claims] 1. A drug spray tube is inserted at a predetermined height position on the inner peripheral surface of a straight tube portion of a blood collection tube inserted into a rack, and the predetermined height of the inner peripheral surface of the straight tube portion of the blood collection tube is inserted from the spray tube. A test device for determining whether or not the amount of the drug applied to the inner peripheral surface of the blood collection tube is sprayed after the drug is sprayed to a predetermined position. A moving device that moves to the inspection position, and a blood collection tube 1 to be inspected from below the rack in which the blood collection tube is inserted
A light source for irradiating an area corresponding to this line, and a CCD camera for taking an image of the inner surface of the blood collection tube from directly above the blood collection tube,
The output signal of the image taken by the CCD camera is A /
An A / D converter for D conversion and a binarization process are performed on the image signal converted by the A / D converter to remove a blackened region, which is a drug application part, from the photographed internal blood collection tube image. An image processing device that determines whether the amount of the drug applied to the inner surface of the blood collection tube is good or bad by counting and comparing the count value of the blackened area with a predetermined reference value. Coating amount inspection device.