JPH08511826A - Granular laundry detergent composition containing lipase and sodium nonanoyloxybenzene sulfonate - Google Patents

Abstract

  (57) [Summary] Granules containing lipases produced by Pseudomonas alcaligenes for good stain removal and bleaching action, specific amounts of alkylalkoxysulfates or polyhydroxy fatty acid amides, and specified proportions of sodium nonanoyloxybenzenesulfonate and sodium perborate A laundry detergent composition is described.

Description

Detailed Description of the Invention       With lipase and sodium nonanoyloxybenzene sulfonate       Granular laundry detergent composition containing                               Technical field   The present invention provides Pseudomonas alcaligenes for good stain removal and bleaching action. Produced by lipase, an amount of alkylalkoxysulfate or Polyhydroxy fatty acid amide, and nonanoyloxybenzenes in specified ratio The present invention relates to a granular laundry detergent composition containing sodium ruphonate and sodium perborate. To do.                               Background technology   Lipases may be incorporated into laundry detergent compositions for improved cleaning performance. Is known. However, it does not smell in granular laundry detergent compositions containing activated bleach. In some cases, the formulation of lipases can result in diminished bleach effectiveness. Granular laundry detergent compositions having both good stain removal and good bleaching action are now available. Was found. The composition is a lipase produced by Pseudomonas alcaligenes. Ze, a specific amount of alkylalkoxysulfate or polyhydroxy fatty acid amide And a specified amount of nonanoyloxybenzenesulfonic acid sodium salt in the specified ratio And sodium perborate.   U.S. Pat. No. 4,861,509 issued Aug. 29, 1989 to Cornelisen et al. And US Pat. No. 4,764 of Cornellicen et al., Issued Sep. 6, 1988. No. 9,173 discloses certain types of fungi and bleaching agents in detergent compositions. And bacterial lipase.   U.S. Pat. No. 4,933,287 issued to Farin et al. On June 12, 1990 A detailed description of lipases useful in cleaning compositions with detergent additives such as bleach, eg For example, it discloses that obtained from Pseudomonas pseudoalcaligenes.                             Disclosure of the invention   The present invention   (A) from about 0.00025 to about 0.015 g of active enzyme per 100 g of composition, Lipase produced by Pseudomonas alcaligenes;   (B) from about 0.5 to about 30% by weight of the composition of an alkylalkoxysulfate. Or polyhydroxy fatty acid amide; and   (C) Sodium nonanoyloxybenzene sulfonate vs. sodium perborate From about 0.5: 1 to about 10: 1, about 1 to about 20% by weight of the composition of nonanoi. Sodium luoxybenzenesulfonate and about 0.5 to about 20% by weight of the composition Sodium perborate And having a pH of about 7 to about 11 in water at about 20 ° C. Laundry detergent composition.                       BEST MODE FOR CARRYING OUT THE INVENTION                               A.Lipase   The granular laundry detergent composition of the present invention contains about 0.000 active enzyme per 100 g of the composition. 25 to about 0.015 g, preferably about 0.0025 to about 0.01 g of Pseudomo Includes lipases produced by Nas alcaligenes. Pseudomonas pseudoa Obtained from lcaligene, believed to be the old name for Pseudomonas alcaligenes As well as the lipases, genetically engineered mutants and their mutants Included in the lipase definition.   About 0.05 to about 0.2% by weight of the composition of 200,000 lipase per gram Most preferred is a lipase produced by Pseudomonas alcaligenes per unit . The lipase unit (LU) has a pH of 7.0, a temperature of 30 ° C, and a substrate of phosphate. Loose Milk with tributyrin and gum arabic in the presence of Ca ++ and NaCl in buffer Produces 1 μmol titratable butyric acid per minute at fixed pH when in suspension It is defined as the amount of lipase.   The lipase produced by Pseudomonas alcaligenes is 1 June 1990. U.S. Pat. No. 4,933,287 issued to Farin et al. Included as a dedication). B.Alkylalkoxysulfate or polyhydroxy fatty acid amide   The granular laundry detergent composition of the present invention comprises from about 0.5 to about 30% by weight of the composition, preferably Is about 1 to about 10% by weight, most preferably about 1 to about 3% by weight of alkylalkoxy. Further included are sulfates or polyhydroxy fatty acids. This is a mixture of the two It is included here. 1.Alkyl alkoxy sulphate   From about 1 to about 10% by weight of the composition, most preferably from about 1 to about 3% by weight of sulphate An average of about 0.5 to about 6 moles, preferably about 1 to about 3 moles of ethylene per mole of salt C10-24, preferably C12-18 alkyl sulphate ethoxylated with oxide Are preferred. Alkylalkoxy sulfated surfactants are typical Has the formula RO (A)_mSO₃M [wherein R is an unsubstituted C_Ten~ C_{twenty four}Alkyl or C_Ten ~ C_{twenty four}Hydroxyalkyl group having an alkyl component, preferably C₁₂~ C₂₀Al Kill or hydroxyalkyl, more preferably C₁₂~ C₁₈Alkyl or hydr Roxyalkyl, A is an ethoxy or propoxy unit and m is greater than 0. Is also large, typically about 0.5 to about 6, more preferably about 0.5 to about 3, M is H or, for example, a metal cation (eg sodium, potassium, lithium , Calcium, magnesium), ammonium or substituted ammonium cations Which is a cation which can be a water-soluble salt or acid.   Alkyl ethoxylated sulphates and alkyl propoxylated sulphates , Intended here. Specific examples of substituted ammonium cations include methyl-, di- Methyl-, trimethyl-ammonium and quaternary ammonium cations, eg For example, tetramethyl-ammonium and dimethylpiperidinium and alkano Amines such as monoethanolamine, diethanolamine, and triethanolamine. Included are cations derived from ethanolamine, and mixtures thereof. . An exemplary surfactant is C₁₂~ C₁₈Alkyl polyethoxylate (1.0) monkey Fate, C₁₂~ C₁₈Alkyl polyethoxylate (2.25) sulfate, C₁₂~ C₁₈Alkyl polyethoxylate (3.0) sulfate, and C₁₂~ C₁₈Alkyl polyethoxylate (4.0) sulphate (where M is sodium It is selected from potassium and potassium). 2.Polyhydroxy fatty acid amide   Polyhydroxy fatty acid amide has the structural formula (I) [In the formula, R¹Is H, C₁~ C_FourHydrocarbyl, 2-hydroxyethyl, 2-hydr Roxypropyl, or mixtures thereof, preferably C₁~ C_FourAlkyl, better More preferably C₁Or C₂Alkyl, most preferably C₁Alkyl (ie methyl) And R²Is C_Five~ C₃₁Hydrocarbyl, preferably linear C₇~ C₁₉Alkyl Or alkenyl, more preferably straight chain C₉~ C₁₇Alkyl or alkenyl, maximum Also preferably straight chain C₁₁~ C_FifteenAlkyl or alkenyl, or mixtures thereof Z is a linear hydrol having at least 3 hydroxyls attached directly to the chain. Polyhydroxyhydrocarbyl having carbyl chain or its alkoxylation derivative Body (preferably ethoxylated or propoxylated)] It consists of a compound of Z is preferably derived from a reducing sugar in a reductive amination reaction. More preferably Z will be glycityl. As a suitable reducing sugar For glucose, fructose, maltose, lactose, galactose, Mannose, and xylose. Z is preferably -CH₂-(CH OH)_n-CH₂OH, -CH (CH₂OH)-(CHOH)_n-1-CH₂OH,- CH₂-(CHOH)₂(CHOR ') (CHOH) -CH₂OH, and those (Wherein n is an integer of 3 to 5 and R'is H or a cyclic group). Or an aliphatic monosaccharide). Glicy where n is 4 Chill, especially -CH₂-(CHOH)_Four-CH₂OH is most preferred.   Preferred polyhydroxy fatty acid amides here are glucose amides, preferably Is C₁₂~₁₈It is N-acetylglucamide. C.Sodium nonanoyloxybenzene sulfonate and sodium perborate   The granular laundry detergent composition of the present invention comprises from about 1 to about 20% by weight of the composition, preferably about 2 to about 15% by weight, most preferably about 5 to about 10% by weight of nonanoyloxyben. Sodium zensulfonate and about 0.5 to about 20% by weight of the composition, preferably About 2 to about 15% by weight, and most preferably about 4 to about 8% by weight sodium perborate. Further includes. Sodium nonanoyloxybenzene sulfonate vs. sodium perborate The ratio of helium is about 0.5: 1 to about 10: 1, preferably about 1: 1 to about 5 :. 1, most preferably about 1: 1 to about 2: 1.   These ingredients are described in Chung et al., US Pat. No. 4,4,4, issued Nov. 1, 1983. No. 12,934 (incorporated herein by reference).   The composition has a pH of about 7 to about 11, preferably about 8 to about 10, in water at about 20 ° C. Have.                             D.Additional optional ingredients 1.Anionic surfactant   The composition optionally comprises from about 2 to about 30% by weight of the composition, preferably about 10%. ~ About 20% by weight of additional anionic or nonionic detergent surfactants Is further included.   Anionic surfactants useful for cleaning purposes are preferably incorporated into the composition. These include soap salts (eg sodium salts, potassium salts, ammonium salts). Salts, and substituted ammonium salts, such as monoethanolamine salts, dietano Ruamine salts and triethanolamine salts), C₉~ C₂₀Straight chain alkyl Benzene sulfonate, C₈~ C_{twenty two}Primary or secondary alkane sulfonate, C₈~ C_{twenty four}Olefin sulfonates, such as British Patent No. 1,082,179 Sulfonation of thermal decomposition products of alkaline earth metal citrates as described herein Sulfonated polycarboxylic acid, alkyl glycerol sulfone produced by Fat, fatty acyl glycerol sulfonate, fatty oleyl glycerol sulphate , Alkylphenol ethylene oxide ether sulphate, paraffin Sulfonates, alkyl phosphates, isothionates, eg acylisos Thionate, N-acyl taurate, methyl tauride fatty acid amide, alkyl Succinamates and sulfosuccinates, monoesters of sulfosuccinates (Especially saturated and unsaturated C₁₂-C₁₈Monoester), sulfosuccinate die Steal (especially saturated and unsaturated C₆~ C₁₄Diester), N-acyl sarcosyne , Alkyl polysaccharide sulphates, eg alkyl polyglucoside monkeys Fates (nonionic nonsulfated compounds described below), branched primary alkyl sulphates And alkyl polyethoxycarboxylates such as the formula RO (CH₂ CH₂O)_kCH₂COO^-M⁺(In the formula, R is C₈~ C_{twenty two}Alkyl and k is 0 to An integer of 10 and M is a soluble salt-forming cation), And fatty acids esterified with isothionic acid and neutralized with sodium hydroxide. You can Resin acids and hydrogenated resin acids are also suitable. Yet another example is "interface Activators and Detergents "(Schwartz, Perry and Birch Volumes I and II) Vol.). A variety of such surfactants are commonly found in Laurin and the like. U.S. Pat. No. 3,929,678, December 30, 975, column 23, column It is also disclosed at line 58 to column 29 line 23 (incorporated herein by reference).   C₁₂~ C₂₀Alkyl sulfate and / or C₉~ C₂₀Straight-chain alkylben Zensulfonate (preferably sodium salt) is preferred for use herein . About 2 to about 10% by weight of the composition of C_{12 to 20}Sodium alkylsulfate and composition About 5 to about 15% by weight of C_{9 to 20}Sodium straight chain alkyl benzene sulfonate ,preferable. 2.Nonionic surfactant   Suitable nonionic detergent surfactants are generally commercially available as of December 30, 1975. -Lin et al., U.S. Pat. No. 3,929,678, column 13, line 14 to column 16 It is disclosed at line 6 (incorporated herein by reference). Exemplary non-limiting types of Useful nonionic surfactants are described below.   1. Polyethylene oxide condensate of alkylphenol, polypropylene Xide condensates and polybutylene oxide condensates. Generally, polyethyleneoxy Decondensates, especially alkylphenol ethoxylates, are preferred.   2. Produced by the condensation of propylene oxide and propylene glycol Condensate of hydrophobic base with ethylene oxide.   3. The products and energy resulting from the reaction of propylene oxide with ethylenediamine Condensate with ethylene oxide.   4. Semipolar nonionic surfactants are a special category of nonionic surfactants. There is, for example, one alkyl moiety having about 10 to about 18 carbon atoms and the number of carbon atoms. Part selected from the group consisting of about 1 to about 3 alkyl groups and hydroxyalkyl groups Water-soluble amine oxide containing 2 parts; alkyl moiety having from about 10 to about 18 carbon atoms Consisting of one and an alkyl group having about 1 to about 3 carbon atoms and a hydroxyalkyl group A water-soluble phosphine oxide containing two moieties selected from the group; and a carbon number of about 1 alkyl moiety of 10 to about 18 and alkyl and hydr of about 1 to about 3 carbon atoms Water-soluble sulfoxy containing one moiety selected from the group consisting of loxyalkyl moieties Sid is mentioned.   5. A hydrophobic group having about 6 to about 30 carbon atoms, preferably about 10 to about 16 carbon atoms; Polysaccharide (eg, polyglycoside) hydrophilic groups containing about 1.3 to about 10 sugar units U.S. Pat. No. 4,565,647 issued January 21, 1986 with Alkyl polysaccharides disclosed in the specification.   6. formula [In the formula, R⁶Is an alkyl group having about 7 to about 21 carbon atoms (preferably about 9 to about 17). Yes, each R⁷Is hydrogen, C₁~ C_FourAlkyl, C₁~ C_FourHydroxyalkyl, and − (C₂H_FourO)_xH (where x is from about 1 to about 3)] Fatty acid amide surfactant. 3.Detergency builder   Inorganic and / or organic detergency builder 1 to about 80% by weight, preferably about 20 ˜about 70 wt% can optionally be incorporated herein.   The inorganic detergency builder includes, but is not limited to, polyphosphoric acid (trypo For rephosphate, pyrophosphate, and glassy polymeric metaphosphate Thus, for example, phosphonic acid, phytic acid, silicic acid (eg alkali metal silicic acid Salts and layered sodium silicates described in U.S. Pat. No. 4,664,839 ), Carbonic acid (including bicarbonate and sesquicarbonate), boric acid, sulfuric acid and aluminoke Alkali metal salts, ammonium salts, and alkanol ammonium salts of formic acid are listed. You can   Examples of carbonate builders include sodium carbonate and sodium sesquicarbonate. And those and German Patent Application No. 2,321,00 published on November 15, 1973. Alkali, including mixtures with ultrafine calcium carbonate as disclosed in No. 1 It is a carbonate of an earth metal and an alkali metal. The preferred aluminosilicate is formula             Na_z[(AlO₂)_z(SiO₂)_y] XH₂O Where z and y are integers of at least 6 and the molar ratio of z to y is 1.0 to about Within the range of 0.5 and x is an integer from about 15 to about 264). Is a zeolite builder having. Preferred synthetic crystalline aluminos useful herein The silicate ion exchange materials are designated as zeolite A, zeolite P (B), and Available as Zeolite X.   Specific examples of polyphosphates include alkali metal tripolyphosphate, sodium, Potassium and ammonium pyrophosphate, sodium, potassium and an Monium pyrophosphate, sodium and potassium orthophosphate, degree of polymerization Is about 6 to about 21 sodium polymetaphosphate, and a salt of phytic acid. .   An example of a phosphonate builder salt is ethane 1-hydroxy-1,1-diphosphone. Water-soluble salts of acids, methylenediphosphonic acid such as trisodium salt and And tripotassium salts and water-soluble salts of substituted methylenediphosphonic acids, such as tri-Natri And tripotassium ethylidene, isopropylidene benzylmethylidene and And halomethylidene diphosphonate. The phosphonate builder salts of the above type are , US Special Issued December 1, 1964 and October 19, 1965 Huh Nos. 3,159,581 and 3,213,030, Roy 1 U.S. Pat. No. 3,422,021 issued Jan. 14, 969 and Quinn U.S. Pat. Nos. 3,4, issued to Bee on September 3, 1968 and January 14, 1969. No. 00,148 and No. 3,422,137 (refer to each here. It is disclosed as a reference).   Polycarboxylate builders include ether polycarboxylates It Examples of useful ether polycarboxylates originated from April 7, 1964 Berg et al., U.S. Pat. No. 3,128,287 and January 18, 1972. U.S. Pat. No. 3,635,830 issued to Lamberti et al. And oxydisuccinate as disclosed in (incorporated herein by reference). Be done. A particular class of ether polycarboxylates useful in the present invention is 1987. Disclosed in US Pat. No. 4,663,071 issued to Bush et al. On May 5, 2014 Has been done.   Further, suitable ether polycarboxylates include cyclic compounds, especially alicyclic compounds. Formula compounds, eg US Pat. No. 3,923,679, 3,835,1 No. 63, No. 4,158,635, No. 4,120,874 And 4,102,903 (all of which are hereby incorporated by reference). Those described in (Transfer). Other useful detergency builders include ATE -Hydroxypolycarboxylate and maleic anhydride with ethylene or vinyl Copolymer with rumethyl ether, 1,3,5-trihydroxybenzene-2,4 , 6-trisulfonic acid, and carboxymethyloxysuccinic acid.   Organic polycarboxylate builders include various alkali metals of polyacetic acid. Also included are salts, ammonium salts and substituted ammonium salts. As an example, Diamine tetraacetic acid and nitrilotriacetic acid sodium salt, potassium salt, lithium And ammonium salts and substituted ammonium salts.   In addition, mellitic acid, succinic acid, oxydisuccinic acid, polymaleic acid, benzene- Polycarboxylic acids such as 1,3,5-tricarboxylic acid and carboxymethyloxysuccinic acid Voxylates, and their soluble salts are also included. Citric acid type builder, eg For example, citric acid and its soluble salts (particularly sodium salts) can be used in granular compositions. It is a polycarboxylate builder that can be used. Other carboxylate builders Deal in U.S. Pat. No. 3,723,32 issued Mar. 28, 1973. The carboxylated carbohydrates disclosed in No. 2 (incorporated herein by reference) are listed. You can   Also, Bush's U.S. Pat. No. 4,566,984 issued Jan. 28, 1986. 3,3-dicarboxy-4-o disclosed in the specification (incorporated herein by reference). The oxa-1,6-hexanedioate and related compounds are present in the detergent composition of the present invention. It is suitable. Examples of useful succinic acid builders include C_Five~ C₂₀Alkyl succinic acid And salts thereof.   Also, examples of useful builders include sodium and potassium carboxy. Methyloxymalonate, carboxymethyloxysuccinate, cis-cyclo Hexane hexacarboxylate, cis-cyclopentane tetracarboxylate, water Soluble polyacrylates (these poly (acrylic acid) s having a molecular weight greater than about 2,000 Acrylate can also be effectively used as a dispersant), and maleic anhydride and vinyl chloride. Examples thereof include salts of a copolymer with rumethyl ether or ethylene.   Other suitable polycarboxylates are Kurtschf, published Mar. 13, 1979. Field et al. U.S. Pat. No. 4,144,226 (herein incorporated by reference). It is a polyacetal carboxylate disclosed in (i). Polycarboxylate Ruder is a U.S. Pat. No. 3,308,067 to Deal issued March 7, 1967. It is also disclosed in the specification (incorporated herein by reference). Other known in the art Organic builders can also be used.   Preferably, the detergency builder of the present invention is carbonic acid, silicic acid, sulfuric acid, phosphoric acid, alkane. From salts of minosilicic acid, citric acid, preferably sodium salts and mixtures thereof Selected from the group. 4.Secondary enzyme   Any preferred ingredients include proteases (most preferred), amylases, peroxidases. Includes secondary enzymes including xydase, cellulase, and mixtures thereof . By "second enzyme" is meant a detergent-compatible enzyme that is also added to the composition in addition to lipase. To taste. A second enzyme from a chemically or genetically modified mutant, and Secondary enzymes from bacterial or fungal origin are included herein. Additional lipase (Ps sources other than eudomonas alcaligenes) can be included here, but are preferably packaged. Does not include.   The amount of second enzyme used in the composition will vary depending on the type of enzyme. In general, live About 0.0001 to 1.0% by weight, more preferably 0.001 to 0.5% by weight Amounts% of these secondary enzymes are preferably used. The same type (eg Enzymes) or enzymes from more than one type (eg cellulases and proteases) Mixtures of may be used.   A suitable cellulase is a fungal cellulase produced by Humicola insolens. US Pat. No. 4,435 to Barbesguard et al., Issued March 6, 1984, showing , 307 (incorporated herein by reference). Also suitable Cellulase is described in British Patent No. 2.075.028 and British Patent No. 2.09. 5.275 and DE-OS 2.247.832. ing. Examples are strains of Humicola insolens (Humicola grisea var.thermoidea) , In particular cellulase produced by Humicola strain DSM1800, and By a Bacillus N fungus belonging to the genus Lomonas or a cellulase 212-producing fungus Cellulases produced and seawater mollusks (Dolabella Auricula Solander) Liver pancreas It is a cellulase extracted from the gut.   Suitable amylases include, for example, British Patent No. 1,296,839 Described in more detail in B. α-amylase from a special strain of licheniforms Is mentioned. Examples of the starch-degrading protein include, for example, rapidase (Rapida). se^TM), Maxamyl^TM) And Termamyl^TM) It   Peroxidase enzymes may be oxygen sources such as percarbonates, perborates. , Persulfate, hydrogen peroxide, etc. They are known in the art , For example, horseradish peroxidase, ligninase, and halo Peroxidases, such as chloroperoxidase and bromoperoxida There is an example. Peroxidase-containing detergent compositions are described, for example, in 1989 1 Transferred to Novo Industries A / S announced on 19th January. PC by Kirk T International Application WO 89/099813 (incorporated herein by reference) It has been disclosed.   About 0.0001 to about 1.0% by weight, based on the active ingredient, preferably about 0.0005. ~ 0.5% by weight, most preferably about 0.002-0.1% by weight of a detergent compatible pro Thease is preferred for use herein. Also included is a mixture of protease enzymes. To be done. The protease must have an animal, plant or microbial (preferred) origin. You can More preferred are serine protease enzymes of bacterial origin. Refined or The unpurified form of this enzyme may be used. Similar to the close structural enzyme variant, chemical Alternatively, the protease produced by the genetically modified mutant is Included by righteousness. Obtained from Bacillus subtilis and / or Bacillus licheniformis The bacterial serine protease enzyme described is particularly preferred. BPN and BPN '(preferred) are mentioned. Also preferred proteases Is a modified bacterial serine protease, such as the European patent filed April 28, 1987. Permit Application No. 87 303761.8 (especially pages 17, 24 and 9) Pp. 8) (herein referred to as "Protease B") and 1986 Described in European Patent Application No. 199,404 of Venegas published on 29 October Thing (a modified bacterial serine proteolytic enzyme called here "protease A" Mean). Protease B, and genetically engineered variants and their Mutants are most preferred for use herein. 5.Other ingredients   Other ingredients suitable for use in the composition, such as water, perfumes, brighteners, condensates. Conditioners such as fumed silica, polyethylene glycol, dyes and A colorant and a peroxy acid can be added. A preferred ingredient is from about 0.5 to about 5% by weight of polyethylene glycol (preferably a molecular weight of 5,000 to 10,000) 0, most preferably 8,000), a fluorescent whitening agent and / or a brightening agent 0.01 to about 0.7% by weight, and perfume about 0.01 to about 1.0% by weight.                         E. FIG.Cloth cleaning method   Furthermore, the present invention provides a cloth   (A) About 0.00025 to about 0.015 g of active enzyme per 100 g of the composition, preferably More preferably about 0.0025 to about 0.01 g of Pseudomonas alcaligenes Lipase produced;   (B) from about 0.5 to about 30%, preferably from about 1 to about 10% by weight of the composition. Rukyalkoxy sulphate or polyhydroxy fatty acid amide; and   (C) Sodium nonanoyloxybenzene sulfonate vs. sodium perborate A composition of about 0.5: 1 to about 10: 1, preferably about 1: 1 to about 5: 1. About 1 to about 20% by weight, preferably about 2 to about 15% by weight of nonanoyloxybenzene. Sodium benzenesulfonate and about 0.5 to about 20% by weight of the composition, preferably Is about 2 to about 15% by weight sodium perborate In an effective amount of a granular laundry detergent composition (the composition having a pH in water at about 20 ° C. of about 7 to about 1). 1) for cleaning the fabric in the wash liquor Provide a way.   The granular detergent composition is usually added to the cleaning liquid in an amount of 1/8 to 1 cup. Stirring is good More preferably it is given in the washing machine for good cleaning. After washing, preferably Dries the wet fabric in a conventional fabric dryer. An effective amount of granular detergent composition is Preferably about 500 to about 7000 ppm, more preferably about 1000 to about 300. It is 0 ppm.   The following examples illustrate the compositions of the invention but do not necessarily limit the scope of the invention. It does not mean that it is not, or otherwise specified.   All parts, percentages and ratios used herein are by weight unless otherwise noted. is there.                                   Example I   The composition of the present invention is as follows. Spray a detergent base with the following composition dry.component                                                       weight% C12-13 straight chain alkylbenzene sulfonate sodium 10.36 C_14-15Sodium alkyl sulfate 4.44 Alkyl ethoxy (E1) sulfate 2.0 Sodium carbonate 8.74 Sodium aluminosilicate (Zeolite A) 21.30 Sodium silicate (ratio 1.6) 1.85 Diethylenetriamine sodium pentaacetate 0.43 Polyethylene glycol (molecular weight 8000) 1.05 Sodium polyacrylate 2.72 Sodium sulfate 8.21 Water, fragrance, miscellaneous ingredients   The following ingredients are mixed with the detergent-based spray-dried particles. After adding other ingredients , Spray on fragrance to particles.Mix / Spray on                                           weight% Sodium carbonate 16.00 Citric acid 3.00 Sodium perborate 5.00 Nonanoyloxybenzene sulfonate sodium 7.42 Fragrance 0.25 Protease enzyme (34mg / g)^★                            0.75 Lipase enzyme^★★                                            0.145^★ European Patent Application No. 87 303761.8 filed on April 28, 1987 A modified bacterial serine protease described herein (referred to herein as Protease B).^★★ With Pseudomonas alcaligenes at 200,000 lipase units per gram Produced lipase (M-from Gist-Blocades, Delft, The Netherlands) 1).   The pH of the composition in water at about 20 ° C is 9.5. Alkyl ethoxy sulphate C12-18 N-acetylglucosamide can be used in place of N-acetylglucosamide can be added to alkyl ethoxy sulphate It Instead of the lipase produced by P. alcaligenes, P. by alcaligenes Variants or mutants of the lipase produced by P. can be used, or P. alcal The lipase variants or mutants produced by igenes are described in P. to alcaligenes Therefore, it can be used in combination with the lipase produced.                                   Example II   The composition of the present invention is as follows. Spray a detergent base with the following formulation dry.component                                                       weight% C12-13 Sodium linear alkylbenzene sulfonate 14.3 C14-15 sodium alkylsulfate 4.1 Phosphate solids 34.0 Sodium carbonate 0.3 Sodium silicate (ratio 2.0) 6.5 Polyethylene glycol (molecular weight 8000) 0.8 Alkyl ethoxy (E1) sulfate 3.0 C_{12 ~ 15}Alcohol polyethoxylate (E9) 0.5 Water, fragrance, sodium sulfate, miscellaneous ingredients   The following ingredients are mixed with the spray dried particles. mixture Sodium carbonate 8.4 Nonanoyloxybenzene sodium sulfonate 8.0 Sodium perborate 4.0 Lipase enzyme (200,000 LU / g) 0.3 Protease enzyme (34mg / g) 0.5 Silicone 0.2   C12-18 N-acetylglucosamide instead of alkyl ethoxy sulphate Can be used or C12-18 N-acetylglucosamide Can be added to the fate. P. of lipase produced by alcaligenes Instead of P. A variant or mutant of lipase produced by alcaligenes Can be used, or P. a variant of lipase produced by alcaligenes or The mutant was designated as P. It can be used in combination with the lipase produced by alcaligenes.                                   Example III   The composition of the present invention is as follows. Spray a detergent base with the following formulation dry.component                                                       weight% C12-14 N-acetylglucosamide 4.3 C14-15 sodium alkylsulfate 13.0 Phosphate solid content 38.0 Sodium carbonate 0.3 Sodium silicate (ratio 2.0) 6.5 Polyethylene glycol (molecular weight 8000) 0.8 Alkyl ethoxy (E1) sulphate 4.3 C_{12 ~ 15}Alcohol polyethoxylate (E9) 0.5 Water, fragrance, miscellaneous ingredients   The following ingredients are mixed with the spray dried particles. mixture Sodium carbonate 8.4 Nonanoyloxybenzene sodium sulfonate 6.0 Sodium perborate 4.0 Lipase enzyme (200,000 LU / g) 0.3 Protease enzyme (34mg / g) 0.5 Silicone 0.2   C12-18 N-acetylglucosamide instead of alkyl ethoxy sulphate Can be used or C12-18 N-acetylglucosamide Can be added to the fate. P. of lipase produced by alcaligenes Instead of P. A variant or mutant of lipase produced by alcaligenes Can be used, or P. a variant of lipase produced by alcaligenes or The mutant was designated as P. It can be used in combination with the lipase produced by alcaligenes.

─────────────────────────────────────────────────── ─── Continued front page    (81) Designated countries EP (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, M C, NL, PT, SE), OA (BF, BJ, CF, CG , CI, CM, GA, GN, ML, MR, NE, SN, TD, TG), AU, BB, BG, BR, BY, CA, CN, CZ, FI, GE, HU, JP, KG, KP, K R, KZ, LK, LV, MD, MG, MN, MW, NO , NZ, PL, RO, RU, SD, SI, SK, TJ, TT, UA, UZ, VN

Claims (1)

[Claims] 1. (A) 0.00025-0.015 g of active enzyme per 100 g of composition, lipase produced by Pseudomonas alcaligenes; (b) 0.5-30% by weight of composition of alkylalkoxysulfate or polyhydroxy fatty acid amide; and (C) 1 to 20% by weight of the composition of sodium nonanoyloxybenzene sulphonate to sodium perborate in a ratio of 0.5: 1 to 10: 1, and 0. A granular laundry detergent composition, characterized in that it comprises 5 to 20% by weight of sodium perborate and has a pH of 7 to 11 in water at about 20 ° C. 2. The granular laundry detergent composition of claim 1, comprising 1 to 10% by weight of the composition of a polyhydroxy fatty acid amide. 3. A granular laundry detergent composition according to claim 1, comprising 0.0025-0.01 g of active enzyme per 100 g of composition, the lipase produced by Pseudomonas nas alcaligenes. 4. 1-10% by weight of the composition of a C10-24 alkyl sulphate ethoxylated with an average of 0.5-6 moles of ethylene oxide per mole of sulphate; 2-15% by weight of the composition of sodium nonanoyloxybenzene sulphonate. 4. A granular laundry according to claim 3, comprising 2-15% by weight of the composition of sodium perborate; and 2-30% by weight of the composition of an additional anionic or detergent nonionic surfactant. Detergent composition. 5. The ratio of sodium nonanoyloxybenzene sulfonate to sodium perborate is 1: 1 to 5: 1 and the composition comprises 1-3% by weight of the composition of polyhydroxy fatty acid amide. Granular laundry detergent composition. 6. 0.0001-1.0% by weight of detergent-compatible protease on an active basis, 2-10% by weight of the composition of C _12-20 sodium alkylsulfate, and 5-15% by weight of the composition of C _9-20. The granular laundry detergent composition of claim 4, further comprising straight chain sodium alkylbenzene sulfonate. 7. 7. The granular laundry detergent composition of claim 6 comprising 4-10% by weight of the composition sodium nonanoyloxybenzene sulfonate and 4-8% by weight of the composition sodium perborate. 8. 7. The granular laundry detergent composition according to claim 6, wherein the ratio of sodium nonanoyloxybenzene sulfonate to sodium perborate is 1: 1 to 2: 1. 9. 9. A granular laundry detergent composition according to claim 8 comprising 1-3% by weight of the composition of _C12-18 alkyl sulphate ethoxylated with an average of 1 to 3 mol ethylene oxide per mol sulphate. 10. Detergency builder selected from 1 to 3% by weight of the composition, 20 to 70% by weight of the composition, of sodium salts of carbonic acid, silicic acid, sulfuric acid, phosphoric acid, aluminosilicic acid and citric acid and mixtures thereof. The granular laundry detergent composition according to claim 9, comprising: 11. A granular laundry detergent composition according to claim 10 comprising 0.5 to 5% by weight of the composition of polyethylene glycol having a molecular weight of 5,000 to 10,000. 12. (A) 0.00025-0.015 g of active enzyme per 100 g of composition, lipase produced by Pseu domonas alcaligenes; (b) 0.5-30% by weight of composition of alkylalkoxysulfates or polyhydroxy fatty acids. Amide; and (c) 1 to 20% by weight of the composition of sodium nonanoyloxybenzene sulfonate and composition of sodium nonanoyloxybenzene sulfonate 0.5: 1 to 10: 1 and the composition. Of 0.5 to 20% by weight of sodium perborate for contact with an effective amount of a granular laundry detergent composition, which composition has a pH of 7 to 11 in water at 20 ° C. Method for cleaning in a cleaning liquid.