JPH08508893A - モノクローナル抗体８８ｂｖ５９、サブクローン及び作製方法 - Google Patents

モノクローナル抗体８８ｂｖ５９、サブクローン及び作製方法

Info

Publication number
JPH08508893A
JPH08508893A JP7520778A JP52077895A JPH08508893A JP H08508893 A JPH08508893 A JP H08508893A JP 7520778 A JP7520778 A JP 7520778A JP 52077895 A JP52077895 A JP 52077895A JP H08508893 A JPH08508893 A JP H08508893A
Authority
JP
Japan
Prior art keywords
cells
antibody
tumor
cell
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7520778A
Other languages
English (en)
Japanese (ja)
Inventor
ハンナ，マイケル・ジー
ハスペル，マーチン・ブイ
フーバー，ハーバート・シー
フレーリー，マリー・エレナ・エイ
コブリン，バリー・ジエイ
Original Assignee
アクゾ・ノベル・エヌ・ベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アクゾ・ノベル・エヌ・ベー filed Critical アクゾ・ノベル・エヌ・ベー
Publication of JPH08508893A publication Critical patent/JPH08508893A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP7520778A 1994-02-04 1995-02-03 モノクローナル抗体８８ｂｖ５９、サブクローン及び作製方法 Pending JPH08508893A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19208994A 1994-02-04 1994-02-04
US08/192,089 1994-02-04
PCT/US1995/001440 WO1995021244A1 (fr) 1994-02-04 1995-02-03 Anticorps monoclonal 88bv59, subclones et procede de production

Publications (1)

Publication Number Publication Date
JPH08508893A true JPH08508893A (ja) 1996-09-24

Family

ID=22708201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7520778A Pending JPH08508893A (ja) 1994-02-04 1995-02-03 モノクローナル抗体８８ｂｖ５９、サブクローン及び作製方法

Country Status (7)

Country Link
EP (1) EP0693121A4 (fr)
JP (1) JPH08508893A (fr)
KR (1) KR960701987A (fr)
AU (1) AU698184B2 (fr)
CA (1) CA2158572A1 (fr)
FI (1) FI954700A (fr)
WO (1) WO1995021244A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828991A (en) * 1984-01-31 1989-05-09 Akzo N.V. Tumor specific monoclonal antibodies
WO1991019797A1 (fr) * 1990-06-15 1991-12-26 New York University Heterohybridomes produisant des anticorps monoclonaux humains contre le vih-1
EP0488470B1 (fr) * 1990-11-26 1997-05-28 Akzo Nobel N.V. Procédé de production d'anticorps monoclonaux

Also Published As

Publication number Publication date
EP0693121A1 (fr) 1996-01-24
CA2158572A1 (fr) 1995-08-10
KR960701987A (ko) 1996-03-28
AU1742595A (en) 1995-08-21
FI954700A0 (fi) 1995-10-03
WO1995021244A1 (fr) 1995-08-10
FI954700A (fi) 1995-10-03
AU698184B2 (en) 1998-10-29
EP0693121A4 (fr) 1999-11-03

Similar Documents

Publication Publication Date Title
US4828991A (en) Tumor specific monoclonal antibodies
EP0151030B1 (fr) Anticorps monoclonaux spécifiques de tumeur
Lobach et al. The human thymic microenvironment. Phenotypic characterization of Hassall's bodies with the use of monoclonal antibodies.
US4997762A (en) Tumor associated monocoloal antibodies derived from human B-cell line
JPS61502820A (ja) ヒトガングリオシドｇｄ↓２に向けられたモノクロ−ナル抗体
JPH06205671A (ja) 形質転換細胞の抽出および培養ならびにそれらに対する抗体の製造
US5474755A (en) Tumor associated monoclonal antibodies
US5106738A (en) Tumor specific monoclonal antibodies
JPH0683666B2 (ja) 腫瘍▲下−▼胎児に特異的なモノクロナ−ル抗体の調製方法および使用方法
US5180814A (en) Tumor specific monoclonal antibodies
AU2004289821B2 (en) Adenocarcinoma specific antibody SAM-6, and uses thereof
JPH08508893A (ja) モノクローナル抗体８８ｂｖ５９、サブクローン及び作製方法
US5348880A (en) Tumor associated monoclonal antibody 81AV/78
US5495002A (en) Tumor associated monoclonal antibody 123AV16
AU651261B2 (en) Tumor associated monoclonal antibody 88BV59
EP0584267B1 (fr) Anticorps monoclonal 81av78 specifique des tumeurs
Sikora Monoclonal Antibodies in the Diagnosis and Treatment of Cancer
Sikora Monoclonal antibodies and drug targeting in cancer
Sikora et al. Monoclonal antibodies