KR960701987A - 단일클론 항체 88bv59, 서브클론 및 이들의 제조 방법(monoclonal antibody 88bv59, subclones and method of making) - Google Patents
단일클론 항체 88bv59, 서브클론 및 이들의 제조 방법(monoclonal antibody 88bv59, subclones and method of making)Info
- Publication number
- KR960701987A KR960701987A KR1019950704282A KR19950704282A KR960701987A KR 960701987 A KR960701987 A KR 960701987A KR 1019950704282 A KR1019950704282 A KR 1019950704282A KR 19950704282 A KR19950704282 A KR 19950704282A KR 960701987 A KR960701987 A KR 960701987A
- Authority
- KR
- South Korea
- Prior art keywords
- monoclonal antibody
- subclones
- making
- cell line
- lymphocyte cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
본 발명은 자가 유래성 종양 항원으로 활성적으로 면역화되는 암 환자의 B-세포에서 유래한 B-세포주에의해 생산되는 단일클론 항체 88BV59에 관한 것이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 88BV59H21-2로 명명되고 ATCC 승인 번호 CRL l1538인 형질 전환된 인간 임파구 세포주.
- 88BV59H21-2V67-66으로 명명되고 ATCC 승인 번흐 CRL l1539인 형질 전환된 인간 임파구 세포주.
- 인간 단일 클론 항체 88BV59의 가변 경쇄 및 가변 중쇄를 포함하는 항체.
- CH2영역이 결실된 것이 특징인 인간 단일 클론 항체 88BV59.
- 임파구 세포주를 골수종과 융합하는 단계 및 응합 생성물을 엡스타인 바르 비루스(Epstein Barr Virus)로 형질 전환시키는 단계를 포함하는 형질 전환된 임파구 세포주의 생산 능력을 증가시키는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19208994A | 1994-02-04 | 1994-02-04 | |
US08/192,089 | 1994-02-04 | ||
PCT/US1995/001440 WO1995021244A1 (en) | 1994-02-04 | 1995-02-03 | Monoclonal antibody 88bv59, subclones and method of making |
Publications (1)
Publication Number | Publication Date |
---|---|
KR960701987A true KR960701987A (ko) | 1996-03-28 |
Family
ID=22708201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950704282A KR960701987A (ko) | 1994-02-04 | 1995-02-03 | 단일클론 항체 88bv59, 서브클론 및 이들의 제조 방법(monoclonal antibody 88bv59, subclones and method of making) |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0693121A4 (ko) |
JP (1) | JPH08508893A (ko) |
KR (1) | KR960701987A (ko) |
AU (1) | AU698184B2 (ko) |
CA (1) | CA2158572A1 (ko) |
FI (1) | FI954700A0 (ko) |
WO (1) | WO1995021244A1 (ko) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4828991A (en) * | 1984-01-31 | 1989-05-09 | Akzo N.V. | Tumor specific monoclonal antibodies |
WO1991019797A1 (en) * | 1990-06-15 | 1991-12-26 | New York University | Heterohybridomas producing human monoclonal antibodies to hiv-1 |
ATE153695T1 (de) * | 1990-11-26 | 1997-06-15 | Akzo Nobel Nv | Verfahren zur herstellung von antikörpern |
-
1995
- 1995-02-03 CA CA002158572A patent/CA2158572A1/en not_active Abandoned
- 1995-02-03 JP JP7520778A patent/JPH08508893A/ja active Pending
- 1995-02-03 KR KR1019950704282A patent/KR960701987A/ko not_active Application Discontinuation
- 1995-02-03 WO PCT/US1995/001440 patent/WO1995021244A1/en not_active Application Discontinuation
- 1995-02-03 AU AU17425/95A patent/AU698184B2/en not_active Ceased
- 1995-02-03 EP EP95909472A patent/EP0693121A4/en not_active Withdrawn
- 1995-10-03 FI FI954700A patent/FI954700A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
AU698184B2 (en) | 1998-10-29 |
AU1742595A (en) | 1995-08-21 |
EP0693121A4 (en) | 1999-11-03 |
FI954700A (fi) | 1995-10-03 |
JPH08508893A (ja) | 1996-09-24 |
CA2158572A1 (en) | 1995-08-10 |
WO1995021244A1 (en) | 1995-08-10 |
EP0693121A1 (en) | 1996-01-24 |
FI954700A0 (fi) | 1995-10-03 |
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Legal Events
Date | Code | Title | Description |
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WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |