JPH08500593A - 置換アザスピラン組成物および該組成物を用いる乾癬の治療方法 - Google Patents

置換アザスピラン組成物および該組成物を用いる乾癬の治療方法

Info

Publication number
JPH08500593A
JPH08500593A JP6506466A JP50646693A JPH08500593A JP H08500593 A JPH08500593 A JP H08500593A JP 6506466 A JP6506466 A JP 6506466A JP 50646693 A JP50646693 A JP 50646693A JP H08500593 A JPH08500593 A JP H08500593A
Authority
JP
Japan
Prior art keywords
compound
carbon atoms
pharmaceutically acceptable
acceptable salt
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6506466A
Other languages
English (en)
Japanese (ja)
Inventor
バジャー，アリソン・メアリー
グリズウォルド，ドン・エドガー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH08500593A publication Critical patent/JPH08500593A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6506466A 1992-08-13 1993-08-12 置換アザスピラン組成物および該組成物を用いる乾癬の治療方法 Pending JPH08500593A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929217121A GB9217121D0 (en) 1992-08-13 1992-08-13 Methods
PCT/US1993/007699 WO1994004151A1 (en) 1992-08-13 1993-08-12 Compositions of substituted azaspiranes and methods of treating psoriasis therewith

Publications (1)

Publication Number Publication Date
JPH08500593A true JPH08500593A (ja) 1996-01-23

Family

ID=10720233

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6506466A Pending JPH08500593A (ja) 1992-08-13 1993-08-12 置換アザスピラン組成物および該組成物を用いる乾癬の治療方法

Country Status (4)

Country Link
EP (1) EP0654997A4 (de)
JP (1) JPH08500593A (de)
GB (1) GB9217121D0 (de)
WO (1) WO1994004151A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
DK0542860T3 (da) * 1990-08-10 1999-02-15 Anormed Inc Immunosuppressive sammensætninger
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
GB9217116D0 (en) * 1992-08-13 1992-09-23 Smithkline Beecham Corp Methods

Also Published As

Publication number Publication date
GB9217121D0 (en) 1992-09-23
WO1994004151A1 (en) 1994-03-03
EP0654997A4 (de) 1997-09-17
EP0654997A1 (de) 1995-05-31

Similar Documents

Publication Publication Date Title
JP3935201B2 (ja) 神経弛緩薬ａｆｓとしてのｎ−置換されたアザビシクロアルカン誘導体
AU619780B2 (en) Immunomodulatory azaspiranes
PT533280E (pt) Novas utilizacoes medicas para antagonistas de taquiquinina
WO1987000752A2 (en) Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters
NZ238141A (en) 1,2,3,4,4a,10b-hexahydro-6-(sulphonamidophenyl)benzo(c)(1,6)naphthyridine derivatives, preparation and pharmaceutical compositions thereof
CA1296730C (en) 6,7,8,9-tetrahydropyrido[1,2-a] indole derivatives
HUT74678A (en) Imidazo[1,2-a]pyrazine-4-one, preparation thereof and drugs containing same
KR100196985B1 (ko) 피페리딘 유도체
HU197842B (en) Process for producing pharmaceutical compositions comprising 2-alkoxy-n-(1-azabicyclo/2.2.2/oct-3-yl)-benzamide derivatives
EP0213499A2 (de) Aminosäure-Derivate, Verfahren zu ihrer Herstellung und Verwendung
US3752823A (en) N alkyl tetrahydrocarbazoles
EP0238753B1 (de) N-substituierte kondensierte Polymethyleniminderivate
JPH08500593A (ja) 置換アザスピラン組成物および該組成物を用いる乾癬の治療方法
EP0587800B1 (de) Immunmodulatorische azaspirane
WO1996016057A1 (en) Certain 1-substituted aminomethyl imidazole and pyrrole derivatives; novel dopamine receptor subtype specific ligands
JPS6323880A (ja) 置換されたヘキサヒドロアリ−ルキノリジン
US20010053783A1 (en) Pharmaceutical compounds
EP0727993A1 (de) Verfahren zur verzögerung aids bei hiv-infektierten patienten durch verabreichung von substituierten azaspiranen
JPS61204186A (ja) ピリダジノピロロイソキノリン誘導体
WO1993007871A1 (en) Methods for the treatment of hyperlipidemia using azaspiranes
IE83827B1 (en) Immunomodulatory azaspiranes
US5455247A (en) Methods for the treatment of hyperlipidemia using azaspiranes
EP0743946A1 (de) 5ht2b rezeptor antagonisten kondensierte indole
US4859669A (en) Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones
WO1995003048A1 (en) Anti-hiv azaspiranes