JPH0848622A - Bathing agent composition - Google Patents

Abstract

PURPOSE:To obtain the subject composition capable of easily and effectively preventing body smell development with low germicide application levels without the need of any burdensome operation such as coating or spraying in taking a bath. CONSTITUTION:This bathing agent composition comprises a combination of a carbon dioxide-generating ingredient with a germicide selected from phenolic germicides (esp. pref. isopropylmethylphenol or p-chloro-m-cresol) and cationic germicides (esp. pref. benzalkonium chloride, benzethonium chloride or cetylpyridinium chloride) and pref. additionally, a cationized polymer (esp. pref. cationized cellulose, cationized starch or cationized dextran). It is preferable that this composition be used so that the concentration of the germicide in bath water stand at 0.1-100 wt.ppm.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a bath agent composition, and more particularly to a bath agent composition containing a specific bactericidal agent and a carbon dioxide-generating component and having an excellent body odor preventing effect.

[0002]

2. Description of the Related Art Recent troubles concerning the body and skin include an unpleasant odor of the body or the like, that is, body odor. Although the cause of body odor has not been sufficiently clarified, it is considered that body odor is caused by secretion of sebaceous glands, apocrine sweat glands, or eccrine sweat glands by the action of microorganisms (for example, J. Invest). . Derm., 77 '413 −416 19
81).

There have been many external products intended to prevent or reduce body odor, and many of these products are usually antiperspirants, bactericides, masking agents for odorous components, adsorbents for odorous components, etc. Is mixed and applied topically to the armpit, legs, etc.

The above antiperspirant suppresses the amount of perspiration,
Most of such antiperspirants are astringent aluminum compounds, and aluminum chloride is usually used. Further, the fungicide, which suppresses the growth of microorganisms that cause axillary odor, such a fungicide,
Hexachlorophene and various quaternary ammonium compounds are used. A substance having a pleasant odor, such as eugenol, is used as the masking agent for the odorous component. Further, as the odorant adsorbent, for example, zinc oxide, activated carbon, zeolite, etc. as disclosed in JP-A-63-43665 are used.

[0005]

However, while the above antiperspirant has an action of reducing sweat, which is a source of sweat odor components, it is inevitable from the physiological point of view to completely suppress perspiration. There is also a drawback in that it has no effect on strong body odor in view of its mechanism of action.

[0006] Further, the above-mentioned bactericide, when applied as an external preparation to the armpit and legs, has an insufficient duration of effect and only temporarily suppresses local odor. It is cumbersome to apply it systemically and is not realistic. In addition, even when it is used as a cleansing agent systemically, it does not remain on the skin at an effective concentration, and a sufficient effect cannot be expected.

Further, the above-mentioned masking agent has a drawback that it may be mixed with body odor to generate an unpleasant odor. Further, although the above-mentioned adsorbent is highly effective for low-boiling components such as lower fatty acids, it has a drawback that it is not very effective for high-boiling components which is one of the causes of "armpit odor" and the like. is there. As described above, conventional external products intended to prevent (or reduce) body odor cannot be said to have sufficient armpit odor prevention effect.

In general, household bath compositions do not contain a bactericide, but liquid bath compositions contain a very small amount of a bactericide for the purpose of preserving them. In addition, a bactericidal agent may be mixed with a bath agent for special medical use. For example, JP-A-54
No. 32636 discloses a bath composition for the treatment of dermatomycosis such as humus, pork snail, etc., which mainly contains salicylic acid, a bactericide containing benzoic acid and thymol, and an astringent, and also British Patent Specification. No. 1570361 discloses a bath salt (bath composition) for halogenating hydroxyphenyl ether and an alkaline carrier for the purpose of sterilizing the skin. However, these bath agent compositions have not been sufficient in terms of durability of body odor suppression.

Therefore, an object of the present invention is to provide a bath agent composition which can effectively prevent the generation of body odor at a low concentration of a bactericide applied.

[0010]

As a result of intensive studies, the present inventors have found that a bath agent composition containing a specific bactericide and a carbon dioxide-generating component in combination can achieve the above object. The inventors have found that this is the case and completed the present invention.

That is, the present invention provides a bath agent composition containing the following components (A) and (B). (A) One or two selected from the group consisting of phenolic fungicides, cationic fungicides and trichlorocarbanilide.
More than one bactericide (B) Carbon dioxide generating component

The bath agent composition of the present invention will be described in detail below.

Component (A) used in the present invention is one or more fungicides selected from the group consisting of phenolic fungicides, cationic fungicides and trichlorocarbanilide. Examples of the agent include isopropylmethylphenol which is a phenol, parachlorometacresol, resorcin, hinokitiol, hexachlorophene which is a halogenated bisphenol, triclosan, and the like, and the cationic bactericide is a quaternary ammonium compound. In addition to certain benzalkonium chlorides, benzethonium chlorides, cetylpyridinium chlorides, chlorhexidine hydrochloride, chlorhexidine gluconate and the like are preferable. Among these fungicides, isopropylmethylphenol, hinokitiol, triclosan, benzalkonium chloride, cetylpyridinium chloride, trichlorocarbanilide are particularly preferable,
Especially, benzalkonium chloride and cetylpyridinium chloride are preferable.

The blending amount of the above-mentioned component (A) is preferably 0.03 to 30% by weight in the composition of the present invention (hereinafter, unless otherwise specified, "%" means "% by weight"), More preferably, it is 0.03 to 15%. The bath agent composition of the present invention preferably has a concentration of the above component (A) in the bath water when dissolved or dispersed in the bath water (when the bath agent composition is used) is 0.1 to 100% by weight. ppm (hereinafter, unless otherwise specified, simply ppm means weight ppm), more preferably 0.5 to 50 ppm, particularly preferably 1 to 30 ppm. For example, for 150 liters of bath water, the above component (A)
However, it is preferable to use the bath agent composition so that the amount becomes 0.015 to 15 g. The concentration of the component (A) in the bath water is 0.
If it is less than 1 ppm, a sufficient body odor preventing effect cannot be expected,
Further, if it exceeds 100 ppm, the amount used per one time becomes large, which is uneconomical.

The carbon dioxide generating component of component (B) used in the present invention is not particularly limited as long as it generates carbon dioxide when dissolved or decomposed in bath water, but carbonic acid is usually used. Used in combination with salt and acid. Examples of the carbonate include sodium hydrogen carbonate, sodium carbonate, sodium sesquicarbonate, potassium hydrogen carbonate, calcium carbonate, potassium carbonate, potassium sesquicarbonate, magnesium carbonate, ammonium hydrogen carbonate, ammonium carbonate, ammonium sesquicarbonate and the like. These may be used alone or in combination of two or more. Of these carbonates, sodium hydrogen carbonate, sodium carbonate, sodium sesquicarbonate, calcium carbonate, and magnesium carbonate are particularly preferable.

As the above-mentioned acid, either an organic acid or an inorganic acid can be used, but a water-soluble and solid acid is preferable. Examples of the organic acid include linear fatty acids such as formic acid, acetic acid, propionic acid, butyric acid, and valeric acid; oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, fumaric acid, maleic acid, and the like. Dicarboxylic acids; acidic amino acids such as glutamic acid and aspartic acid; oxy acids such as glycolic acid, lactic acid, hydroxyacrylic acid, α-oxybutyric acid, glyceric acid, tartronic acid, malic acid, tartaric acid and citric acid, and the acidity of these organic acids Salt etc. are mentioned. Examples of the inorganic acid include phosphoric acid, potassium dihydrogen phosphate, sodium dihydrogen phosphate, sodium sulfite, potassium sulfite, sodium pyrosulfite (sodium metabisulfite), potassium pyrosulfite (potassium metabisulfite), acidic Examples thereof include sodium hexametaphosphate, potassium acid hexametaphosphate, sodium acid pyrophosphate, potassium acid pyrophosphate, sulfamic acid and the like, and these can be used alone or in combination of two or more kinds. Of these acids, aliphatic dicarboxylic acids such as succinic acid and fumaric acid, malic acid, and acid salts thereof are particularly preferable.

The above component (B) comprises a carbonate and an acid,
The amount of carbonate added is preferably 5 to 5 in the composition of the present invention.
80%, more preferably 10-70%, and the acid content is preferably 10-300 with respect to the carbonate.
%, And more preferably 20 to 200%.

The bath composition of the present invention contains 0.01% thereof.
The aqueous solution (40 ° C.) has a pH of 4 to 7, particularly 6.0 to 6.7.
Are preferred. Here, the above-mentioned pH measurement is performed as follows. That is, immediately before measuring the pH, 5
In a liter beaker, prepare 5 liters of standard water at 40 ° C. 0.5 g of the bath agent composition is weighed and dissolved therein (0.01%). When the above-mentioned bath agent composition is a tablet, it is crushed to an appropriate size using a mortar, and then about 0.3
A mass of ˜0.5 g is selected and precisely weighed, standard water is weighed into a 5 liter beaker so that the concentration becomes 0.01%, and the sample is dissolved. Immediately after melting, mix so that the hot water is uniform,
The pH is measured by the Japanese Pharmacopoeia General Test Method. The standard water used here was prepared by dissolving 73.36 mg of calcium chloride dihydrate in 5 liters of ion-exchange distilled water, and then adding sodium bicarbonate 8
It is prepared by dissolving 3.83 mg and immediately after dissolving the baking soda, blowing carbon dioxide gas to adjust the pH to 7.0.

The bath agent composition of the present invention is used so that the concentration of carbon dioxide gas in the bath water when dissolved or dispersed in the bath water (when the bath agent composition is used) is 60 ppm or more. Is preferred. Carbon dioxide concentration in the bath water is 60p
When it is less than pm, a sufficient body odor preventing effect is not obtained.

The carbon dioxide gas generated by the carbon dioxide gas generating component (B) is not known to have a particularly strong bactericidal effect, so the gas partial pressure of the bath water, the vasodilatory effect of carbon dioxide gas, and the skin tissue. By a mechanism such that the circulation promoting action increases the adsorption amount or permeation amount of the bactericide [component (A)] to the skin, a synergistic effect of the carbon dioxide gas and the bactericide [component (A)] is brought about, It is considered to exert the effect of strongly suppressing the generation of body odor after bathing.

The bath agent composition of the present invention further contains (C) a cationized polymer to further increase the adsorption amount (force) or penetration amount (force) of the bactericide to the skin,
The effect of more strongly suppressing the generation of body odor after bathing is exhibited. As the cationized polymer, diethylaminated ethyl ellulose, diisopropylaminated ethylcellulose, cationized cellulose such as dimethylaminated ethylcellulose, cationized starch, cationized dextran, cationized dextrin, cationized vinylpyrrolidone polymer, cationized guar gum, Examples include cationized polypeptides and chitosan. Of these, cationized cellulose, cationized vinylpyrrolidone polymer, cationized guar gum and cationized polypeptide are particularly preferable. The cationization degree of the cationized polymer is preferably in the range of 0.01 to 10, particularly 0.1 to 2. Outside of the above range, the body odor preventing effect tends to be lowered.

The content of the above component (C) in the composition of the present invention is preferably 0.01 to 30%, more preferably 0.03 to 7.5%. In particular, when the blending amount of the component (A) and the blending amount of the component (B) are in the above-mentioned preferred ranges, it is preferable that the blending amount of the component (C) is in the above range. The concentration of the component (C) in the bath water of the bath agent composition of the present invention when dissolved or dispersed in the bath water (when the bath agent composition is used) is preferably 0.05.
It is used so as to be -100 ppm, more preferably 0.1-25 ppm. When the concentration of the component (C) in the bath water is less than 0.05 ppm, the synergistic action with the component (A) is not exhibited, and thus a sufficient body odor preventing effect cannot be expected, and when it exceeds 100 ppm, it is used per dose. It is uneconomical because of the large amount.

When the above component (C) is used, it is particularly preferable that the above component (A) is a cationic bactericide. That is, it is preferable to use a cationic bactericide as the component (A), a carbon dioxide generating component as the component (B), and a cationized polymer as the component (C) in combination.

The bath agent composition of the present invention may contain optional components usually used in bath agents, in addition to the essential components (A) and (B) and the above component (C). Examples of such optional components include the following (a) to
Examples of such as (g) are listed.

(A) Inorganic salts Sodium chloride, borax, sodium sulfate, sodium sulfide, sodium nitrate, sodium thiosulfate, sodium polyphosphate, sodium phosphate, magnesium oxide,
Potassium chloride, potassium sulfide, aluminum sulfate, alum, etc. (A) Crude drugs Fennel, psyllium, chamomile, cinnamon, safflower, peony,
Ginger, iris, syringa, Japanese dwarf, cock, sycamore, valerian, juniper, Toshi, lightly-loaded, bukuro, carrot, peach leaves, etc. (C) Pigments Yellow dye 4, blue 1, yellow 202 (1) and other tar dyes specified by the Ordinance of the Ministry of Health and Welfare, food additives such as the dyes of attached tables I and II, chlorophyll, riboflapine, crocin, safflower, anthraquinone Natural pigments that are recognized as products. (D) Oils and fats Isopropyl palmitate, isopropyl myristate, squalane, squalene, liquid paraffin, white petrolatum, etc. (E) vitamins Vitamin A, vitamin C, vitamin D, vitamin E, etc. (F) Fragrances (G) Others Sulfur, Yunohana, Mineral sand, Mica powder, Neutral clay, Rice bran, Glycerin, Surfactants, Dispersants, Binders, Sequestering agents, Sugars, and other components necessary for formulation etc.

In the present invention, the bath agent composition refers to a composition which is used by dissolving it in water in a bathtub or hot water at the time of bathing.

The usage of the bath agent composition of the present invention is as follows:
For example, the following method may be mentioned. That is, at the time of bathing, the bath agent composition is treated with water or hot water (preferably 15 to 45).
C., more preferably 38 to 42.degree. C.) and soak for 3 to 30 minutes. Here, in the case of a whole body bath (soaking under the shoulder or below the chest), the bath agent composition is preferably dissolved in 100 to 250 liters of water or hot water. Also,
In the case of a half-body bath (soaking below the waist), the bath agent composition is preferably dissolved in 50 to 150 liters of water or hot water. Further, in the case of a foot bath (soaking below the knee), the bath agent composition is preferably dissolved in 5 to 100 liters. After taking a bath, you may take a shower to wash away the bath water, but it is better to wipe the bath water lightly with a towel without taking a shower.

The bath agent composition of the present invention may be produced by any production method as long as the above essential components (A) and (B) are uniformly mixed. Further, the dosage form of the bath agent composition of the present invention may be powder, tablet, granule, paste or the like.

[0029]

EXAMPLES The present invention will be specifically described below with reference to test examples (examples and comparative examples), but the present invention is not limited to these examples.

Test Example 1 (Sensory Evaluation) 35 male panelists were tested for A group, B group, C group, D group, E group,
The F group and the G group were divided into 5 groups each, and a sensory evaluation was performed on the bath agent composition and the whole body cleansing agent having the compositions shown in [Table 1] below. Five persons in the group A washed their lower limbs with a cleaning agent obtained by removing triclosan from the whole body cleaning agent of Comparative Example 4, and then bath water prepared by dissolving 50 g of the bath agent of Example 1 in 150 liters of warm water. Then, the lower limbs were partially bathed, and after bathing, the lower limbs were lightly wiped with a towel. The group B, the group C, the group D, the group E, and the group F each use the bath agent of Example 2, Example 3, Comparative Example 1, Comparative Example 2, and Comparative Example 3 with a single-use amount of 50 g. Other than that, they were washed and bathed in the same manner as 5 persons in group A. Five people in the G group washed their lower limbs with 5 g of the whole body cleansing agent of Comparative Example 4, and then bathed with the bath agent of Comparative Example 1 as in the other groups. After 24 hours from the bathing, sensory evaluation was performed according to the following criteria. The results are shown in [Table 2] below.

Sensory evaluation criteria (foot odor) score 3; strong 2; medium 1; weak 0; none

[0032]

[Table 1]

[0033]

[Table 2]

Test Example 2 Thirty-five male panelists were administered to Group A, Group B, Group C, Group D, Group E,
Each of the F group and the G group was divided into 5 persons. Each panel of each group other than the group C was washed and bathed using the cleaning agent and the bath agent composition in exactly the same manner as in Test Example 1, and each panel of the group C was prepared by using the bath agent composition of Example 3. Cleaning was performed in exactly the same manner as in Test Example 1 except that the bath agent composition of Example 4 was used instead.
I took a bath. After bathing, the lower limbs were lightly wiped with a towel, and immediately thereafter, the lower limbs were immersed in 3 liters of hot water and lightly scrubbed with a sponge. Each of the washings was placed in a 5 liter beaker and allowed to stand in a 40 ° C. environment for 24 hours, and then the turbidity of each washing was measured with a Poic integrating sphere thermometer. The results are shown in [Table 3] below.

[0035]

[Table 3]

From the results of Test Example 1 shown in Table 2 above,
According to the bath agent composition of the present invention (Example 1, Example 2 and Example 3; Group A, Group B and Group C), a bath agent containing the bactericidal agent of the present invention but not generating carbon dioxide gas. Composition (Comparative Example 2; Group E), bath agent composition that generates carbon dioxide gas but does not contain a bactericide (Comparative Example 1; Group D), bath agent that generates carbon dioxide gas but contains another bactericide Composition (Comparative Example 3;
Suppressing the generation of unpleasant body odor such as foot odor over a long period of time as compared with the case of the whole body cleanser containing the sterilizing agent according to the present invention and the carbon dioxide gas (Comparative Example 4; G group) You can see that. Further, according to the bath agent composition of the present invention (Example 1, Example 2 and Example 3), the generation of axillary odor and sweat odor can be suppressed for a long time. Further, from the results of Test Example 2 shown in [Table 3] above, the turbidity of the skin wash solution after bathing was determined to be the bath agent composition of the present invention (Example 1, Example 2 and Example 4; Group A, B).
It can be seen that the bath composition of the present invention exerts a sufficient bactericidal effect against the bacteria on the skin, which is the cause of the generation of body odor, when the bath agent composition is suppressed to a low level by taking a bath using the groups B and C).

[0037]

EFFECTS OF THE INVENTION According to the bath agent composition of the present invention, it is possible to effectively prevent the generation of body odor only by taking a bath using the bath agent composition, despite the low concentration of the bactericide applied. No need for complicated application or spraying.

Claims (9)

[Claims] 1. A bath agent composition comprising the following components (A) and (B): (A) One or two selected from the group consisting of phenolic fungicides, cationic fungicides and trichlorocarbanilide.
More than one bactericide (B) Carbon dioxide generating component 2. The bath agent composition according to claim 1, which further comprises (C) a cationized polymer. 3. The phenolic fungicide which is the above component (A) is one or more fungicides selected from the group consisting of isopropylmethylphenol, parachlorometacresol, resorcin, hinokitiol, hexachlorophen and triclosan. The bath agent composition according to claim 1 or 2. 4. The cationic bactericide as the component (A) is one or more bactericides selected from the group consisting of benzalkonium chloride, benzethonium chloride, cetylpyridinium chloride, chlorhexidine hydrochloride and chlorhexidine gluconate. The bath agent composition according to claim 1 or 2, which is an agent. 5. The bath agent composition according to claim 1 or 2, wherein the component (B) comprises a carbonate and an acid. 6. The component (C) is one selected from the group consisting of cationized cellulose, cationized starch, cationized dextran, cationized dextrin, cationized vinylpyrrolidone polymer, cationized guar gum and cationized polypeptide. Alternatively, the bath agent composition according to claim 2, which is two or more kinds of cationized polymers. 7. The content of the component (A) is 0.03 to 30% by weight in the composition, the component (B) is composed of a carbonate and an acid, and the content of the carbonate is the composition. Medium 5-80
% By weight, and the amount of acid blended is 10 to 30 with respect to the above carbonate.
The bath agent composition according to claim 1, which is 0% by weight. 8. The blending amount of the component (A) is 0.03 to 30% by weight in the composition, the component (B) is composed of a carbonate and an acid, and the blending amount of the carbonate is the composition. Medium 5-80
% By weight, and the amount of acid blended is 10 to 30 with respect to the above carbonate.
The bath agent composition according to claim 2, wherein the content of the component (C) is 0.01 to 30% by weight in the composition. 9. The bath agent composition according to claim 1, which is used such that the concentration of the component (A) in the bath water when the bath agent composition is used is 0.1 to 100 ppm by weight. .