KR101308959B1 - Low-Irritative Powder Composition for Washing - Google Patents

Abstract

The present invention relates to a cleansing powder composition which minimizes irritation to the skin and has an excellent cleaning effect. The present invention primarily includes a weak acid amino acid and an isethionate system, which are hypoallergenic human cleansing agents, to minimize the irritation and to the human body. The present invention relates to a mild cleansing powder composition capable of providing a secondary irritation-reducing effect by not containing harmful chemical preservatives, and providing a soft texture to the skin while enhancing the cleansing effect by containing a mud component.

Hypoallergenic, Facial Powder, Mud, Unprotected

Description

Low-Irritative Powder Composition for Washing

The present invention relates to a powder composition for hypoallergenic cleansing.

In general, the face wash is responsible for removing makeup and sebum and sebum of the skin in order to clean the skin. Skin contaminants are classified into exogenous contaminants (various chemicals in the air, dust, bacteria, cosmetics used in the skin, etc.) and endogenous contaminants (sebum, sebum altered matter, various excretion contained in sweat, aged keratin, etc.) These pollutants are attached to the skin and play a role in propagating various bacteria, adversely affect the skin health.

Surfactants conventionally used to remove the skin contaminants include alkyl sulfates, alkyl ether sulfates, and higher fatty acid salts. However, these have been a problem for skin irritation such as skin pulling, itching, rough skin, etc., and milder hypoallergenic surfactants have been required.

The hypoallergenic material has various kinds such as acyl taurate, sulfosuccinate, isethionate, glutamate, fatty alcohol sulfate, glyceryl ester sulfate, and the like. Has been. In addition, it is known that the least irritation in the skin irritation is an amino acid-based surfactant and excellent foaming and rinsing ability, but in order to achieve this effect has a disadvantage of using 60-70% by weight of the composition.

Amino acid surfactants and isethionate surfactants are widely known as surfactants for the preparation of hypoallergenic human cleansers. Amino acid-based surfactants exhibit high skin safety, but they often feel slippery and sticky after washing without foaming, and have a disadvantage in that the unit price increases. On the other hand, the isethionate-based surfactant is also hypoallergenic, has excellent foaming power and excellent cleaning effect, but has high hygroscopicity and may cause agglomeration after elapse of time in face wash powders.

Another ingredient that may irritate the skin, such as the surfactants listed above, is a chemical preservative. Preservatives are responsible for destroying and killing bacterial and fungal cell membranes. The human body is made up of cells, and the cell membrane that surrounds them is surrounded by lipids and proteins to protect the cells by selective permeation that accepts only beneficial substances. Preservatives can destroy these cell membranes, causing substances that should not enter the cell to enter the cell, and as a result, substances within the cell can spill out of the cell, destroying the environment in which the cell can live, and causing the cell to die.

The present inventors have made diligent efforts to solve the above problems. As a result, the present invention uses an amino acid-based surfactant, which is the least irritant surfactant, as a main surfactant, and an isethionate-based surfactant widely known as another hypoallergenic surfactant. Using as a supplement to prepare a face-wash powder composition to minimize skin irritation.

Accordingly, it is an object of the present invention to provide a powder composition for hypoallergenic face wash.

In order to achieve the above object, the present invention provides a powder composition for hypoallergenic face wash.

Hypoallergenic facial cleansing composition of the present invention is a hypoallergenic surfactant having a detergency in order to minimize irritation, i.e., an amino acid-based surfactant by using an isethionate-based surfactant as a main base and an amino acid-based surfactant. It compensates for the deterioration of the bubble formation force and the cleaning effect which may occur at the time of use. In addition, the hypoallergenic cleansing powder composition of the present invention has the property of maintaining the cleansing effect on the skin, moisturizing and physiological effects, and no preservatives without chemical preservatives by adding a mud component for a higher cleaning effect. Grant.

Amino acid-based surfactants are widely known as a typical hypoallergenic detergent for preparing detergents, and are known to have good biodegradability, but are often slippery and sticky after washing without foaming well, and have a problem in that the unit price increases. Preferred amino acid surfactants for use in the face-wash powder composition of the present invention are (a) acyl amino acid sodium surfactants selected from the group consisting of powdered sodium cocoyl glutamate and sodium lauroyl glutamate and (b) potassium It is selected from the group consisting of acyl amino acid potassium-based surfactants selected from the group consisting of lauroyl glutamate and potassium myristoyl glutamate, more preferably acyl amino acid sodium-based surfactants.

In addition, the isethionate-based surfactant has been evaluated as having low skin irritation due to low skin penetration and residual property compared to soap and synthetic detergent ingredients, and is known to have excellent cleaning power and foaming power. Aggregation may occur after time in face wash.

Preferred isethionate-based surfactants for use in the face-wash powder composition of the present invention include ammonium cocoyl isethionate, sodium cocoyl isethionate, sodium lauroyl isethionate, sodium myristoyl isethionate and sodium It is selected from the group consisting of oleoyl isethionate, with sodium cocoyl isethionate being more preferred.

Therefore, when the two components are properly combined, the usability is improved along with high skin safety, thereby enabling mild washing powder having a better cleaning effect.

In addition, the powder detergent composition of the present invention, by containing the mud component to enhance the cleaning effect that can be somewhat dropped due to the application of the hypoallergenic surfactant, dry feeling commonly seen in the face-wash powder by the organic and mineral components contained in the mud component It provides a conditioning effect to alleviate stiffness and stiffness, it can provide a mild cleansing powder composition to exhibit an antiseptic effect without containing a chemical preservative.

The mud used as an active ingredient in the composition of the present invention is formed by the decomposition of the flora and fauna, soil, salts, etc. of the flora and fauna for a long time by the geological and chemical action and decomposition of microorganisms, various inorganic substances and trace elements In addition, it contains organic substances and is rich in hormone-like substances and vitamins such as prolan and estrogen. The various ingredients in the mud are responsible for: Hormones and vitamins in the mud may have a good therapeutic effect on the body's metabolism, circulation, and nervous system. In addition, antibacterial, antifungal action is effective in the treatment of trauma. Generally speaking, mud therapy is widely known to have anti-inflammatory action, metabolism promotion, growth and regeneration of cells, tissues and nerves, immune function, analgesic action, and hormone function promotion.

According to a preferred embodiment of the present invention, the amount of the amino acid surfactant is 15-50% by weight, more preferably 20-40% by weight based on the total cosmetic composition. When the total weight of the amino acid surfactant is less than 15% by weight, it is difficult to produce a cleaning effect, and when the amount exceeds 50% by weight, there is a problem in that the unit price increases.

According to a preferred embodiment of the present invention, the amount of the isethionate-based surfactant is 2-15% by weight, more preferably 5-10% by weight based on the total cosmetic composition. When the total weight of the isethionate-based surfactant is less than 2% by weight, it is more difficult to improve foaming force than when the amino acid-based surfactant is used alone, and when it exceeds 15% by weight, the contents may aggregate due to moisture. Can be.

In a preferred embodiment of the invention the amount of mud is 5-30% by weight, even more preferably 8-20% by weight, most preferably 10-15% by weight, based on the cosmetic composition. When the total weight of the mud is less than 5% by weight, the effect is less likely to appear, and when the total weight is greater than 30% by weight, there is a problem that a powdering phenomenon is caused due to fine powder properties.

In addition to the above essential components, the face-wash powder composition of the present invention may be formulated in a range that does not impair the effects of the present invention, such as an aqueous component, an antioxidant, a UV absorber, a perfume, a cosmetic, etc., in addition to the essential components. Can be.

The face-wash powder composition of the present invention contains an amino acid-based surfactant as a main component, and contains an isethionate-based surfactant as an auxiliary component, thereby primarily minimizing irritation, having an excellent cleaning effect, and cleaning by containing a mud component. Along with enhancing the effect, it can give a soft touch to the skin.

The following is described in more detail with reference to the following embodiments of the present invention configured as described above. It will be apparent, however, to those skilled in the art that these embodiments are for describing the present invention and that the scope of the present invention is not limited to these embodiments.

Manufacturing example : Preparation of Facial Washing Powder Composition

To prepare a powder-type formulation using the Henschel mixer (Examples 1-3) Hensel mixer of the present invention in the composition of Table 1 below, the effects of amino acid-based surfactants, isethionate-based surfactants and mud In order to compare the composition of Comparative Example 1-4 with a composition as shown in Table 1 below. As the amino acid surfactant of Table 1, sodium lauroyl glutamate and sodium cocoyl glutamate were mixed and used, and sodium cocoyl isethionate was used as the isethionate surfactant.

ingredient Example
One Example
2 Example
3 Comparative Example
One Comparative Example
2 Comparative Example
3 Comparative Example
4 Amino acid system 36.0 31.0 31.0 - 31.0 31.0 36.0 Isetionate system - 5.0 5.0 5.0 5.0 5.0 - Fatty acid carboxylates - - - 31.0 - - - Mannitol 25.0 25.0 25.0 25.0 25.0 25.0 25.0 maltose 10.0 10.0 5.0 19.8 19.8 20.0 19.8 Starch 18.0 18.0 18.0 18.0 18.0 18.0 18.0 Silica 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Mud Powder 10.0 10.0 10.0 - - - - Paraoxybenzoic acid ester 0.2 0.2 - 0.2 0.2 - 0.2

Experimental example 1: Makeup removal effect experiment

First, the washing powder composition of Examples 1-3 and Comparative Examples 1-4 prepared in the above Preparation Example was dissolved in distilled water to prepare an 8% aqueous solution to confirm the makeup removal effect. The weight (weight B) of the calf skin of 3 cm x 3 cm was measured. 1 ml of 8% sample solution was applied thereon, rubbed lightly with hand for 30 seconds, immediately rinsed with tap water of constant flow rate for 30 seconds, completely dried, and weighed (weight C).

Makeup removal rate is calculated according to the following equation 1 from the values of the weight A, B, C and the results are shown in Table 2 below.

Sample Makeup removal rate (%) Example 1 94% Example 2 97% Example 3 97% Comparative Example 1 97% Comparative Example 2 95% Comparative Example 3 95% Comparative Example 4 93%

Looking at the results of Table 2, the detergent composition containing the amino acid surfactant, isethionate surfactant and mud (Examples 2 and 3) is a detergent composition containing an amino acid surfactant and the mud (Example 1) And it can be seen that the makeup removal rate is higher than the cleaning composition (Comparative Examples 2 and 3) containing an amino acid-based surfactant and an isethionate-based surfactant. That is, the cleaning composition containing all of an amino acid surfactant, an isethionate surfactant, and a mud had the best cleaning effect.

Experimental example 2: Sebum removal rate

Sebum before using the eye wash powders of Examples 1-3 and Comparative Examples 1-4 prepared in the above Preparation Example, using Sebumeter SM 810 (Courage + Khazaka, Germany), which is most often used to measure the amount of sebum in skin. After measuring the amount of, and using the face-wash powder again, the amount of sebum was measured to determine the removal rate of sebum according to the following equation (2).

This experiment was averaged by measuring the amount of sebum in the forehead area of five subjects. The amount of sebum on the general skin surface is shown in Table 3 (unit mg / cm 2).

division Back of hand Neck, body Cheek (ball) forehead Dry skin <6 <66 <6 <99 Neutral skin - 67-110 - 99-220 Oily skin ＞ 6 ＞ 110 ＞ 6 ＞ 220

The results of the experiment are shown in Table 4 below.

Sample Sebum Levels (Forehead) Sebum removal rate Before cleaning After cleaning Example 1 240 16 93.3% Example 2 220 11 95.0% Example 3 238 12 95.7% Comparative Example 1 252 14 94.4% Comparative Example 2 244 23 90.6% Comparative Example 3 233 22 90.5% Comparative Example 4 235 16 93.2%

Experimental Example 3: Skin Irritation Test

30 subjects were tested for the degree of skin irritation of the face wash composition (Example 1-3) and Comparative Example 1-3 composition of the present invention. Each composition was treated in the Finn Chamber, patched on the inner region of the upper arm, and the stimulation values after 24 hours and 48 hours were measured. The average value of the stimulus values is shown in Table 5 below. The degree of stimulation was determined by the criteria in Table 6 below.

division Example
One Example
2 Example
3 Comparative Example
One Comparative Example
2 Comparative Example
3 Comparative Example
4 Stimulation degree
Average 0.45 0.79 0.55 3.21 1.12 0.89 0.45

Stimulus levels 0-0.75 0.76-2.00 2.01-3.5 3.51-5.0 5.01-7.50 7.51 or more Judgment No stimulation Unstimulated Weak stimulation Light stimulus Moderate irritation River stimulation

As shown in Table 5, the facial wash composition of Examples 1-3 was unstimulated or non-stimulated, but the stimulation level was low, but the compositions of the comparative examples were found to have higher stimulation values. Therefore, the face-wash powder composition of the present invention has almost no skin irritation and it can be seen that the skin irritation relief effect is also very good.

Experimental Example 4: Evaluation of Skin Feeling

10 professional subjects are prepared for each evaluation item such as skin pulling and skin feeling (freshness, stickiness) (however, subjects may overlap), and the face-wash powder composition (Example 1-3) Example 1-4 The usability of the composition was evaluated. Evaluation was performed according to the reference score of Table 7, and the results of summing the scores of the subjects of each item are shown in Table 8 below.

division Reference score The effect is felt high 5 I feel the effect 4 The effect is felt a little 3 The effect is felt only slightly 2 I cannot feel the effect One

division Example
One Example
2 Example
3 Comparative Example
One Comparative Example
2 Comparative Example
3 Comparative Example
4 Skin pull 48 48 48 30 38 39 37 Skin feeling 42 44 44 33 36 38 37

As shown in Table 8, the facial wash composition of Example 1-3 has less skin pulling, a fresh feel and no stickiness compared to the composition of Comparative Examples 1-4. Therefore, it can be seen that the face wash composition of the present invention has excellent skin feel, such as skin pulling and skin feeling.

Experimental Example 5: Antistress Test

In order to evaluate the antiseptic force, E. coli (Escherichia coli; ATCC 8739), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa, 20-30 g of the cosmetics of Examples 1-3 and Comparative Examples 1-4 were used. Mixed bacterial liquids such as Lujinosa (Pseudomonas aeruginosa; ATCC 99027) were added and mixed so as to have an initial concentration of 10 ⁶ cfu (colony forming unit) / g per sample. The cells were incubated for 4 weeks in a 30-32 ° C. thermostat and 1 g of each cosmetic was taken at intervals of 1, 7, 14, 21 and 28 days to measure the number of viable cells. The measurement results are shown in Table 9 below.

In the case of mold, a mixture of Penicillium citrinum (ATCC 9849) and Aspergillus niger (ATCC 16404) was added and mixed at an initial concentration of 10 ⁶ cfu / g. While culturing, the presence of anomaly and mycelia and spores on the surface of the sample were observed at 7 days intervals, and the results are shown in Table 9 below.

Sample Bacteria (cfu / g)
mold* Initial number of bacteria Day 1 Day 7 Day 14 Day 21 Day 28 Example 1 1 × 10 ⁶ 8000 <100 <100 <100 <100 - Example 2 1 × 10 ⁶ 8000 <100 <100 <100 <100 - Example 3 1 × 10 ⁶ 11000 <100 <100 <100 <100 - Comparative Example 1 1 × 10 ⁶ 8000 <100 <100 <100 <100 - Comparative Example 2 1 × 10 ⁶ 8000 <100 <100 <100 <100 - Comparative Example 3 1 × 10 ⁶ 15000 200 <100 <100 <100 + Comparative Example 4 1 × 10 ⁶ 8000 <100 <100 <100 <100 -

*-： No bad smell, hyphae and spores for 8 weeks

   + ： Mold develops on walls and lids within 4 weeks

   ++ ： Smells on bad smell and part of the surface within 4 weeks

   +++ ： Deodorization and mold on the entire surface within 4 weeks

As shown in Table 9, in the case of Comparative Example 3, which does not contain a preservative, there was an antiseptic effect, but it was found that by containing the mud component, it showed a more excellent antiseptic effect.

The present invention provides a powder composition for hypoallergenic face wash. The hypoallergenic composition of the present invention is based on an amino acid-based surfactant exhibiting a cleaning effect, and has been reduced in primary stimulation with the aid of an isethionate-based surfactant, and improved cleaning effect and usability by adding mud. In addition, the stability of the preservative system can be improved to minimize the stimulus as much as possible.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the same is by way of illustration and example only and is not to be construed as limiting the scope of the present invention. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

Claims (4)

The main surfactant includes an amino acid-based surfactant and an auxiliary surfactant as an active ingredient, an isethionate-based surfactant and a mud, wherein the amino acid-based surfactant comprises (a) sodium cocoyl glutamate and sodium lauroyl glutamate in powder form. Acyl amino acid sodium-based surfactant consisting of; and (b) acyl amino acid potassium-based surfactant consisting of potassium lauroyl glutamate and potassium myristoyl glutamate, wherein the isethionate surfactant is ammonium coco Powder composition for hypoallergenic face wash, characterized in that selected from the group consisting of one isethionate, sodium cocoyl isethionate, sodium lauroyl isethionate, sodium myristoyl isethionate and sodium oleoyl isethionate . delete According to claim 1, wherein the amino acid surfactant is based on the total weight of the face-wash powder composition 15-15% by weight, 2-15% by weight of the isethionate-based surfactant, 5-30% by weight of the mud powder Powder composition for hypoallergenic cleansing, characterized in that. The powder composition for hypoallergenic face wash according to claim 1, wherein the powder composition does not contain a chemical preservative.