JPH07506842A - 二本鎖を有する非毒性リボソーム不活性化蛋白（ｒｉｐ），その製法および適用 - Google Patents

二本鎖を有する非毒性リボソーム不活性化蛋白（ｒｉｐ），その製法および適用

Info

Publication number
JPH07506842A
JPH07506842A JP6519616A JP51961694A JPH07506842A JP H07506842 A JPH07506842 A JP H07506842A JP 6519616 A JP6519616 A JP 6519616A JP 51961694 A JP51961694 A JP 51961694A JP H07506842 A JPH07506842 A JP H07506842A
Authority
JP
Japan
Prior art keywords
protein
nigrin
chain
rip
toxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6519616A
Other languages
English (en)
Japanese (ja)
Inventor
ヒルベス・フアン，トマス
フェレーラス・ロドリゲス，ホセ・ミゲル
イグレシアス・アルバレス，ロサリオ
シトレス・ゴンサレス，ルシア
アリアス・バジェホ，フランシスコ・ハビエル
ロホ・ロドリゲス，マリア・アンヘレス
ムニョス・マルティネス，ラケル
ヒメネス・ロペス，ピラル
マルティネス・デ・ベニート，フェルナンド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Valladolid
Original Assignee
Universidad de Valladolid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9300409A external-priority patent/ES2074936B1/es
Priority claimed from ES9300408A external-priority patent/ES2074935B1/es
Application filed by Universidad de Valladolid filed Critical Universidad de Valladolid
Publication of JPH07506842A publication Critical patent/JPH07506842A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Enzymes And Modification Thereof (AREA)
JP6519616A 1993-03-02 1994-03-02 二本鎖を有する非毒性リボソーム不活性化蛋白（ｒｉｐ），その製法および適用 Pending JPH07506842A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ES9300409 1993-03-02
ES9300409A ES2074936B1 (es) 1993-03-02 1993-03-02 Proteina nigrina d de la planta sambucus nigra l., procedimiento para su obtencion y su utilizacion.
ES9300408 1993-03-02
ES9300408A ES2074935B1 (es) 1993-03-02 1993-03-02 Proteina ebulina 1 de la planta sambucus ebulus l., procedimiento para su obtencion y su utilizacion
PCT/ES1994/000020 WO1994020540A1 (es) 1993-03-02 1994-03-02 PROTEINAS INACTIVADORAS DE RIBOSOMAS (RIPs) DE DOS CADENAS NO TOXICAS, PROCEDIMIENTO PARA SU PREPARACION Y APLICACIONES

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2003427447A Division JP2004113252A (ja) 1993-03-02 2003-12-24 二本鎖を有する非毒性リボソーム不活性化蛋白、その製法および調製物

Publications (1)

Publication Number Publication Date
JPH07506842A true JPH07506842A (ja) 1995-07-27

Family

ID=26154697

Family Applications (2)

Application Number Title Priority Date Filing Date
JP6519616A Pending JPH07506842A (ja) 1993-03-02 1994-03-02 二本鎖を有する非毒性リボソーム不活性化蛋白（ｒｉｐ），その製法および適用
JP2003427447A Withdrawn JP2004113252A (ja) 1993-03-02 2003-12-24 二本鎖を有する非毒性リボソーム不活性化蛋白、その製法および調製物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2003427447A Withdrawn JP2004113252A (ja) 1993-03-02 2003-12-24 二本鎖を有する非毒性リボソーム不活性化蛋白、その製法および調製物

Country Status (5)

Country Link
US (1) US6008324A (OSRAM)
EP (1) EP0652231A1 (OSRAM)
JP (2) JPH07506842A (OSRAM)
AU (1) AU6208494A (OSRAM)
WO (1) WO1994020540A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7563466B2 (en) 2001-05-23 2009-07-21 Izun Pharmaceuticals Corporation Herbal compositions for the treatment of mucosal lesions

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2095187B1 (es) * 1994-12-27 1997-09-01 Univ Valladolid Proteinas inactivadoras de ribosomas, denominadas alfa-ebulitina, beta-ebilitina y gamma-ebulitina, de la planta sambucus ebulus, l., procedimiento para su obtencion y su utilizacion.
US5876728A (en) * 1995-02-15 1999-03-02 Howard David Kass Natural composition extracted from plants used in the treatment of cancer
ES2095190B1 (es) * 1995-03-06 1997-09-01 Univ De Valladolid Y En Repres Proteinas inactivadoras de ribosomas, denominadas alfa-nigritina, beta-nigritina y gamma-nigritina, de la planta sambucus nigra l., procedimiento para su obtencion y su utilizacion.
ES2098190B1 (es) * 1995-05-24 1998-01-01 Univ Valladolid Proteinas inactivadoras de ribosomas, denominadas nigrina 11 y nigrina 12, de la planta sambucus nigra l., procedimiento para su obtencion y preparacion.
ES2104510B1 (es) * 1995-08-01 1998-05-16 Univ Valladolid Proteina inactivadora de ribosomas, denominada nigrina f, de la planta sambucus nigra, l., procedimiento para su obtencion y preparacion.
ES2115520B1 (es) * 1996-02-05 1999-02-16 Univ Valladolid Proteinas inactivadoras de ribosomas (rips), denominadas beetin 27 y beetin 29, de la planta beta vulgaris, procedimiento para su obtencion y utilizacion.
ES2125175B1 (es) * 1996-10-07 1999-10-16 Univ Valladolid Proteina inactivadora de ribosomas, denominada nigrina b basica, de la planta sambucus nigra l., procedimiento para su obtencion y su utilizacion.
US6812327B1 (en) 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
DE19752597A1 (de) * 1997-11-27 1999-06-10 Madaus Ag Verwendung von Lektinzubereitungen bei der Bekämpfung von Harnblasenkarzinomen
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
DK1294769T3 (da) 2000-06-16 2011-04-26 Human Genome Sciences Inc Antistoffer der immunspecifikt binder til BLyS
WO2002016411A2 (en) 2000-08-18 2002-02-28 Human Genome Sciences, Inc. Binding polypeptides and methods based thereon
AU2002238052A1 (en) 2001-02-20 2002-09-04 Zymogenetics, Inc. Antibodies that bind both bcma and taci
EP1241267A3 (en) * 2001-03-14 2004-01-02 Viscum AG Enzyme activity test using fluorescently labeled oligonucleotide substrate
FR2825927B1 (fr) * 2001-06-13 2004-08-06 Hotchen Myriam Composition antivirale incorporant des lectines
EP1497415B1 (en) 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Methods for detection or modulation of the interaction of a cytokine receptor with its ligand
FR2849040A1 (fr) * 2002-12-18 2004-06-25 Arandi Pharma Polypeptides a activite antivirale
WO2005097184A2 (en) 2004-03-26 2005-10-20 Human Genome Sciences, Inc. Antibodies against nogo receptor
US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
WO2007123765A2 (en) 2006-03-31 2007-11-01 Human Genome Sciences Inc. Neutrokine-alpha and neutrokine-alpha splice variant
EP3744839A1 (en) * 2019-05-31 2020-12-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. A genetically encoded protein synthesis inhibitor (gepsi)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742046A (en) * 1984-08-03 1988-05-03 Medisearch S.A. Methods and compositions for inhibiting the infectious activity of viruses

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7563466B2 (en) 2001-05-23 2009-07-21 Izun Pharmaceuticals Corporation Herbal compositions for the treatment of mucosal lesions
US8075926B2 (en) 2001-05-23 2011-12-13 Izun Pharmaceuticals Corporation Herbal compositions for the treatment of mucosal lesions
US9855307B2 (en) 2001-05-23 2018-01-02 Izun Pharmaceuticals Corporation Herbal compositions for the treatment of mucosal lesions

Also Published As

Publication number Publication date
AU6208494A (en) 1994-09-26
WO1994020540A1 (es) 1994-09-15
JP2004113252A (ja) 2004-04-15
US6008324A (en) 1999-12-28
EP0652231A1 (en) 1995-05-10

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