JPH07292391A - Cleaning agent composition - Google Patents

Abstract

PURPOSE:To provide a cleaning agent composition containing a specific phosphoric acid ester, a cationic bactericide and a metal chelating agent, giving low stimulation to the skin, having excellent bactericidal effect and comfortable to use. CONSTITUTION:This cleaning agent composition contains (A) 2-60wt.% of one or more substances selected from phosphoric acid ester of formula I (R<1> is a 8-15C hydrocarbon group; X<1> and X<2> each is H, an alkali metal, ammonium, a basic amino acid or an alkanolamine containing a 2-3C hydroxyalkyl group) and its salt, (B) 0.05-3.0wt.% of a cationic bactericide and (C) 0.5-3mol (based on 1mol of the component B) of a metal chelating agent. Preferably, the component B is a benzalkonium salt of formula II or formula III (R<2> is a 8-24C hydrocarbon group; R<3> is a 8-16C alkyl or alkenyl; Z is an anion) and the component C is ethylenediaminetetraacetic acid, hydroxyethyl ethylenediaminetriacetic acid, 1-hydroxye thylidene-1, 1-diphosphonic acid, citric acid, etc.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a detergent composition, and more particularly to a detergent composition which is mild to skin, has an excellent bactericidal effect, and has a good feeling in use.

[0002]

2. Description of the Related Art Generally, cationic bactericides are widely used in the field of hygiene because they have a broad antibacterial spectrum band and have fast-acting properties. Attempts have been made to develop a cleaning agent having both a cleaning effect and a bactericidal effect by combining with an activator.

However, when an anionic surfactant is used or in the presence of a substance having an anionic charge such as a protein, the activity of the above cationic bactericide is greatly reduced. As a method for preventing such activity decrease, a method of coating the cationic bactericidal agent with a polymeric nonionic surfactant or a pH-sensitive polymer, a method of adding a large excess of the cationic bactericidal agent, etc. are known. The former does not substantially prevent the decrease in activity, while the latter is not preferable from the economical point of view.

Therefore, it has been desired to develop a detergent composition that is mild to the skin, has a sufficient bactericidal action, and has a good feeling in use.

[0005]

Means for Solving the Problems As a result of intensive studies in view of such circumstances, the present inventors have found that a composition containing a phosphoric acid ester, a cationic bactericidal agent, and a metal chelating agent in specific proportions is applied to the skin. It has been found that it has a low irritant property, an excellent bactericidal action, and a good feeling of use during washing, and has completed the present invention.

That is, the present invention provides the following component (A),
(B) and (C): (A) General formula (1)

[0007]

[Chemical 4]

(In the formula, R ¹ represents a straight-chain or branched-chain hydrocarbon group having 8 to 15 carbon atoms, and X ¹ and X ² are each hydrogen, an alkali metal, ammonium, a basic amino acid, or a carbon number of 2 to 2 3 represents an alkanolamine having a hydroxyalkyl group of 3), one or more selected from a phosphoric acid ester represented by: and 2 to 60% by weight, (B) a cationic bactericide, 0.05 to 3.0% by weight. %, (C) metal chelating agent 0.5 to 3 times the molar amount of the component (B), and a cleaning agent composition.

The phosphoric acid ester of the component (A) and its salt used in the present invention are represented by the above general formula (1). In the formula (1), the number of carbon atoms represented by R ¹ is 8
Examples of the straight-chain hydrocarbon group having 15 to 15 include a straight-chain alkyl group or alkenyl group having 8 to 15 carbon atoms, and include octyl group, nonyl group, decyl group, undecyl group, dodecyl group, tridecyl group, and tetradecyl group. A linear alkyl group such as a group and a pentadecyl group is preferable. In addition, carbon number 8 to 15
The branched chain hydrocarbon group of R ⁴ --CH (CH ₃ ) CH _2- (R ⁴
Is preferably a linear hydrocarbon group having 5 to 12 carbon atoms). Examples of the linear hydrocarbon group having 5 to 12 carbon atoms represented by R ⁴ include a linear alkyl group or alkenyl group having 5 to 12 carbon atoms, a pentyl group,
Straight-chain alkyl groups such as hexyl group, heptyl group, octyl group, nonyl group, decyl group, undecyl group and dodecyl group are preferred. In the present invention, in addition to these methyl-branched alkyl phosphates, ethyl-branched, propyl-branched, butyl-branched or pentyl-branched alkyl phosphates may be mixed.

Of X ¹ and X ² , the alkali metal is, for example, lithium, sodium, potassium or the like; the basic amino acid is, for example, arginine, lysine, histidine, ornithine or the like; the alkanolamine is, for example, Examples include triethanolamine, diethanolamine, monoethanolamine and the like.

Of these phosphoric acid esters or salts thereof, sodium, potassium or triethanolamine salts of phosphoric acid esters having a dodecyl group or a linear or branched hydrocarbon group having 8 to 15 carbon atoms are particularly preferable.

The component (A) can be used alone or in combination of two or more kinds, and the compounding amount thereof in the detergent composition of the present invention is 2 to 60% by weight (hereinafter, simply indicated by "%"). , Preferably 4 to 40%, particularly preferably 5 to 30%. If it is less than 2%, sufficient detergency cannot be obtained, and if it exceeds 60%, compounding becomes difficult, which is not preferable.

As the cationic bactericidal agent of the component (B) used in the present invention, a benzethonium salt, a benzalkonium salt, a pyridinium salt, or a cationic surfactant in which the counter ion of these bactericidal agents is converted into another anion. Examples of bactericides include chlorhexidine and biguanide bactericides such as chlorhexidine gluconate. Of these, the following general formula (2)

[0014]

[Chemical 5]

A benzalkonium salt represented by the formula (wherein R ² represents a hydrocarbon group having 8 to 24 carbon atoms and Z ⁻ represents an anion) is preferable.

In the formula (2), the carbon number represented by R ² is 8 to ²
As the hydrocarbon group having 4 carbon atoms, a hydrocarbon group having 12 to 18 carbon atoms is preferable, and a hydrocarbon group having 12 to 14 carbon atoms, such as lauryl group and myristyl group, is particularly preferable.

Z is, for example, a halogen atom such as chlorine or bromine; an amino acid, a fatty acid, a phosphoric acid ester having a linear or branched alkyl group or an alkenyl group having 1 to 30 carbon atoms, a phosphonic acid ester, or a sulfone. Anion residue of acid ester or sulfate ester; degree of polymerization: 3
Examples thereof include anionic oligomers or polymers containing a formalin condensate of a sulfonated product of a polycyclic aromatic compound which has the above-mentioned styrene sulfonic acid or may have a hydrocarbon group as a substituent. Of these, a chlorine atom and an anion residue of an alkyl phosphate ester are particularly preferable because they are more excellent in bactericidal properties.

As the component (B), especially the following general formula (3)

[0019]

[Chemical 6]

(In the formula, R ² has the same meaning as described above, and R ^2
3 is preferably a linear or branched alkyl group or alkenyl group having 8 to 16 carbon atoms).

The component (B) can be used alone or in combination of two or more, and its content in the detergent composition of the present invention is 0.05 to 3.0%, preferably 0. 1 to
2.0%, particularly preferably 0.2 to 1.5%.
If it is less than 0.05%, a sufficient bactericidal effect cannot be obtained and 3.0
If it exceeds%, the problem of irritation to the skin or the like occurs.

The metal chelating agent of the component (C) used in the present invention is not particularly limited as long as it has the ability to chelate metal ions, and examples thereof include ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid and diethylenetriaminepentaacetic acid. , Phosphonic acids such as nitrilotriacetic acid, triethylenetetraminehexaacetic acid, 1-hydroxyethylidene-1,1-diphosphonic acid, tripolyphosphoric acid, ethylene glycol bis (2
-Aminoethyl ether) tetraacetic acid, citric acid, maleic acid, polyacrylic acid, isoamylene-maleic acid copolymer, silicic acid, gluconic acid, hydroxybenzyliminodiacetic acid, iminodiacetic acid and salts thereof.
Among these, ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, 1-hydroxyethylidene-1,1-diphosphonic acid, citric acid, tripolyphosphoric acid or salts thereof are particularly preferable.

The amount of the component (C) to be added to the detergent composition of the present invention is 0.5 to 3 times, preferably 0.7 to 2 times, and particularly preferably 0 to that of the above component (B). .8-1.
It is 5 times the molar amount. If it is less than 0.5 times the mole of the component (B), a sufficient bactericidal effect cannot be obtained, and it may be more than 3 times the mole.
It is economically disadvantageous because the effect does not change.

In the detergent composition of the present invention, as component (A), triethanolamine dodecylphosphate or potassium phosphate ester having a linear or branched hydrocarbon group having 9 to 11 carbon atoms is used, and the component ( It is preferable to use a combination of benzalkonium hexadecylphosphate or benzalkonium chloride as B) and disodium ethylenediaminetetraacetate as component (C).

In addition to the anionic and cationic surfactants, shampoos, rinses and the like may contain a metal chelating agent for the purpose of improving foaming properties and detergency at low temperatures. It is needless to say that the amount of the metal chelating agent in this case is extremely small unlike the present invention, and the effect exerted is also completely different from that of the present invention.

The detergent composition of the present invention, if necessary,
Other surfactants such as higher fatty acid salts, alkyl sulfates, alkyl sulfonates, polyoxyethylene alkyl sulfates, alkylbenzene sulfonates, N-acyl sarcosine salts, N-acyl-N-methyl taurine salts,
Anionic surfactants such as alpha-olefin sulfonate, alkyl ether acetate, polyoxyethylene alkyl ether acetate, etc., nonionic surfactants such as polyoxyethylene alkyl ether, sugar ester-based, sugar ether-based, sugar amide-based etc. , Imidazoline-based, betaine-based, and other amphoteric surfactants may be optionally used in combination as long as the effects of the present invention are not impaired.

Further, the cleaning composition of the present invention may optionally contain, as other additives, components commonly used in cleaning agents, as long as the effects of the present invention are not impaired. For example, propylene glycol, sorbitol,
Moisturizers such as glycerin, carboxyvinyl polymers, viscosity modifiers such as methyl cellulose, ethanol, polyoxyethylene glycol distearate, pearling agents, fragrances, dyes, ultraviolet absorbers, antioxidants, anti-inflammatory agents, preservatives, etc. Can be blended.

The detergent composition of the present invention can be manufactured into a desired dosage form such as solid, gel, paste and liquid by mixing, heating and stirring the above components in a conventional manner. The cleansing composition of the present invention is suitable for cleaning the body of skin, hair and the like, and particularly preferably for cleaning the skin.

[0029]

The cleaning composition of the present invention is mild to the skin, has an excellent bactericidal action, and has a good feeling during use.

[0030]

EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited thereto.

Example 1 A detergent composition whose composition is shown in Tables 1 and 2 was produced by the following method. (Production method) A liquid detergent was obtained by sequentially dissolving other components in purified water.

The bactericidal effect of each of the obtained liquid detergent compositions was measured by the following method, and the feeling of use was evaluated by the following method and criteria. Table 1 together with the results
And shown in Table 2.

(Measurement of bactericidal effect) A bactericidal test method, a dilution agent was prepared for each of the obtained detergents, and a test bacterium (Escherichia coli IFO 397) was prepared for each.
2, Pseudomonas aeruginosa
IFO 12689) was inoculated and the concentration and time for 100% sterilization were determined. That is, bacteria (about 10 ⁹ to 10 ¹⁰ cells) pre-cultured in SCD medium (manufactured by Nippon Pharmaceutical Co., Ltd.)
0.1 ml / ml), and use sterile distilled water to obtain a predetermined concentration (concentration of bactericide 1, 5, 10, 25, 50, 75, 100, 20
10 ml of the test solution diluted to 0,300,500 ppm) was inoculated and allowed to act at room temperature. Fixed time (5, 10, 1
Every 5 to 30 minutes), one platinum loop of the bacterial contact liquid was sampled, and a micro Petri dish (COR) containing 0.3 ml of SCD medium for post-culture
NING, 96-Cell Wells) was inoculated. The cells were cultured at 30 ° C. for 3 days, the growth of the bacteria was visually observed, and the strength of the effect was judged by the number of sterilized areas. That is,
It was judged by measuring the places where the bacteria did not grow on the micro planter (maximum 40). The larger the number, the stronger the sterilizing power.

(Evaluation Method of Use Feeling and Evaluation Criteria) For each detergent composition, 10 panelists each of men and women washed their bodies and sensory evaluation was performed. For the evaluation, an average value was calculated according to the following criteria. When the average value was 4.5 or more, it was very good (⊚), when 3.5 to 4.4, it was good (∘), and 2.5 to 3 Usually, the case of 0.4 (△), 2.4
The following cases were judged to be defective (x).

(1) Bubble breakage during rinsing; 5: Good bubble breakage. 4: Foam is slightly broken. 3: Normal. 2: Foam is a little bad. 1: Poor out of foam. (2) Feeling of sliminess after rinsing; 5: No slimy feeling. 4: Slightly slimy. 3: Normal. 2: Slightly slimy. 1: Slimy. (3) Feeling of dryness after drying; 5: No dryness. 4: Somewhat not touching. 3: Normal. 2: Slightly dry. 1: Bulky.

[0036]

[Table 1]

[0037]

[Table 2]

A) Dia Doll 115L (manufactured by Mitsubishi Kasei Co., Ltd.) R ¹ in the formula (1) is C ₁₁ : C ₁₃ : C ₁₅ = 47: 31:
22 (weight ratio). Linear: branched = 47:53. Breakdown of branched alkyl phosphate ester is methyl branched 63
%, Ethyl branch 17%, propyl branch 9%, butyl branch 8%, pentyl branch 3%. b) Dobanol 231 (manufactured by Mitsubishi Petrochemical Co., Ltd.) R ¹ in the formula (1) is C ₁₂ : C ₁₃ = 43: 57 (weight ratio). Linear: branched = 1: 9. Breakdown of branched alkyl phosphate ester is methyl branch 40
%, Ethyl branch 16%, propyl branch 15%, butyl branch 19%, pentyl branch 10%.

Example 2 A liquid detergent composition having the following composition was produced.

[Table 3] (Components) (%) (1) Triethanolamine monolaurylphosphate 20.0 (2) Triethanolamine laurate 4.0 (3) Lauroyl amide propyl dimethylcarboxybetaine 2.0 (4) Hexa Benzalkonium decylphosphate 1.0 (5) Ethylenediaminetetraacetic acid disodium 1.0 (Number of moles relative to bactericide) (6) Perfume 0.5 (7) Dibutylhydroxytoluene 0.2 (8) Ethanol 4.0 (9) Purified water balance

(Manufacturing method) Components (1) to
After dissolving (3) and cooling it, the components (4)-
(8) was added to obtain a liquid detergent composition. When the body was washed with the obtained detergent composition, the deodorant effect was excellent due to its high bactericidal power, and the foaming and foaming were good, and the sliding property was good from the time of rinsing to the time after drying, and the feeling of use was excellent. .

Example 3 A liquid detergent composition having the following composition was produced.

(Table 4) (Components) (%) (1) Phosphate potassium ^a) 20.0 (2) Potassium laurate 3.0 (3) Potassium myristate 1.5 (4) Lauroyl amide propyl dimethyl carboxybetaine 1 .0 (5) cationized cellulose 0.1 (6) benzalkonium chloride 1.0 (7) ethylenedimine disodium tetraacetate 1.0 (number of moles with respect to fungicide) (8) perfume 0.5 (9) Dibutylhydroxytoluene 0.2 (10) Ethanol 4.0 (11) Purified water balance a) Same as Example 1.

(Production method) Components (1) to
After dissolving (3) and cooling it, the components (4)-
(8) was added to obtain a liquid detergent composition. When the body was washed with the obtained detergent composition, the deodorant effect was excellent due to its high bactericidal power, and the foaming and foaming were good, and the sliding property was good from the time of rinsing to the time after drying, and the feeling of use was excellent. .

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[Procedure amendment]

[Submission date] May 26, 1994

[Procedure Amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0038

[Correction method] Change

[Correction content]

A) Diadol 115L (manufactured by Mitsubishi Kasei Co., Ltd.) R ¹ in the formula (1) is C ₁₁ : C ₁₃ : C ₁₅ = 47:
31:22 (weight ratio). Linear: branched = 47:53. Breakdown of branched alkyl phosphate ester is methyl branched 63
%, Ethyl branch 17%, propyl branch 9%, butyl branch 8%, pentyl branch 3%. b) Dobanol 23I (manufactured by Mitsubishi Petrochemical Co., Ltd.) R ¹ in the formula (1) is C ₁₂ : C ₁₃ = 43: 57 (weight ratio). Linear: branched = 1: 9. Breakdown of branched alkyl phosphate ester is methyl branch 40
%, Ethyl branch 16%, propyl branch 15%, butyl branch 19%, pentyl branch 10%.

[Procedure Amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0041

[Correction method] Change

[Correction content]

Example 3 A liquid detergent composition having the following composition was produced.

[Table 4]

Claims (4)

[Claims] 1. The following components (A), (B) and (C): (A) General formula (1) (In the formula, R ¹ represents a linear or branched hydrocarbon group having 8 to 15 carbon atoms, X ¹ and X ² are each hydrogen, an alkali metal, ammonium, a basic amino acid or a hydroxy group having 2 to 3 carbon atoms. Which represents an alkanolamine having an alkyl group) 2 to 60% by weight of one or more kinds selected from a phosphoric acid ester represented by the formula (4) and a salt thereof, (B) a cationic bactericide 0.05 to 3.0% by weight, C) Metal chelating agent 0.5 to 3 times mol of the component (B), a cleaning composition comprising: 2. A cationic fungicide (B) has the following general formula (2): (In the formula, R ² represents a hydrocarbon group having 8 to 24 carbon atoms, and Z 2
^- The detergent composition according to claim 1, wherein the benzalkonium salts represented by an anion). 3. A cationic fungicide (B) is represented by the following general formula (3): (In the formula, R ² represents a hydrocarbon group having 8 to 24 carbon atoms, and R ^2
3 detergent composition according to claim 1, wherein the benzalkonium salts represented by a straight or branched chain alkyl or alkenyl group having 8 to 16 carbon atoms). 4. The metal chelating agent (C) is selected from ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, 1-hydroxyethylidene-1,1-diphosphonic acid, citric acid, tripolyphosphoric acid and salts thereof. The cleaning composition according to any one of claims 1 to 3.