JPH0676329B2 - 多発硬化症治療剤 - Google Patents

多発硬化症治療剤

Info

Publication number
JPH0676329B2
JPH0676329B2 JP61504828A JP50482886A JPH0676329B2 JP H0676329 B2 JPH0676329 B2 JP H0676329B2 JP 61504828 A JP61504828 A JP 61504828A JP 50482886 A JP50482886 A JP 50482886A JP H0676329 B2 JPH0676329 B2 JP H0676329B2
Authority
JP
Japan
Prior art keywords
multiple sclerosis
carbon atoms
general formula
compound
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61504828A
Other languages
English (en)
Japanese (ja)
Other versions
JPS63500869A (ja
Inventor
ゲルハルト ムンダー,パウル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MATSUKUSU PURANKU G TSUA FUERUDERUNKU DERU UITSUSENSHAFUTEN EE FUAU
Original Assignee
MATSUKUSU PURANKU G TSUA FUERUDERUNKU DERU UITSUSENSHAFUTEN EE FUAU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MATSUKUSU PURANKU G TSUA FUERUDERUNKU DERU UITSUSENSHAFUTEN EE FUAU filed Critical MATSUKUSU PURANKU G TSUA FUERUDERUNKU DERU UITSUSENSHAFUTEN EE FUAU
Publication of JPS63500869A publication Critical patent/JPS63500869A/ja
Publication of JPH0676329B2 publication Critical patent/JPH0676329B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP61504828A 1985-08-28 1986-08-28 多発硬化症治療剤 Expired - Lifetime JPH0676329B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3530767.6 1985-08-28
DE19853530767 DE3530767A1 (de) 1985-08-28 1985-08-28 Mittel gegen multiple sklerose
PCT/EP1986/000506 WO1987001257A2 (en) 1985-08-28 1986-08-28 Agent against multiple sclerosis

Publications (2)

Publication Number Publication Date
JPS63500869A JPS63500869A (ja) 1988-03-31
JPH0676329B2 true JPH0676329B2 (ja) 1994-09-28

Family

ID=6279592

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61504828A Expired - Lifetime JPH0676329B2 (ja) 1985-08-28 1986-08-28 多発硬化症治療剤

Country Status (5)

Country Link
US (1) US4778788A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0236390B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0676329B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3530767A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1987001257A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3918082A1 (de) * 1989-06-02 1991-01-24 Max Planck Gesellschaft Mittel gegen autoimmunerkrankungen
US5064816A (en) * 1989-08-10 1991-11-12 Sandoz Ltd. Heterocyclic phospholipids useful in treating multiple sclerosis
EP0412941B1 (en) * 1989-08-10 1996-05-15 Sandoz Ltd. Phospholipids for the treatment of multiple sclerosis
US5182271A (en) * 1989-08-10 1993-01-26 Sandoz Ltd. Thioether, keto-ester and alkyl phospholipids useful in treating multiple sclerosis
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
US5082846A (en) * 1990-08-30 1992-01-21 Sandoz Ltd. Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis
DE4222910A1 (de) * 1992-07-11 1994-01-13 Asta Medica Ag Neue Phospholipidderivate
US6172050B1 (en) 1992-07-11 2001-01-09 Asta Medica Aktiengesellschaft Phospholipid derivatives
JP2002532553A (ja) * 1998-12-21 2002-10-02 インケイサ.ソシエダ アノニマ 有害な胃腸副作用を引き起こさない有力な抗炎症剤としてのエーテルリゾリン脂質の使用
EP1338651B9 (en) * 2000-12-01 2007-05-09 Astellas Pharma Inc. Method of screening remedy for diabetes
DK2089711T3 (da) 2006-11-10 2012-11-26 Alphaptose Gmbh Fremgangsmåder og sammensætninger til detektion af receptor-ligand-mimetika
CN101610758A (zh) * 2006-11-10 2009-12-23 阿尔法普托斯有限公司 含有三取代甘油化合物的口服剂型
WO2013156630A1 (en) 2012-04-20 2013-10-24 Alphaptose Gmbh S-enantiomer of a tri-substituted glycerol compound
GB201208850D0 (en) * 2012-05-18 2012-07-04 Alphaptose Gmbh Tri-subsituted glycerol compounds for use in the treatment of clinically isolated syndrome and/or multiple sclerosis

Also Published As

Publication number Publication date
US4778788A (en) 1988-10-18
JPS63500869A (ja) 1988-03-31
EP0236390A1 (de) 1987-09-16
DE3530767A1 (de) 1987-03-12
DE3530767C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-03-16
DE3677368D1 (de) 1991-03-07
WO1987001257A2 (en) 1987-03-12
EP0236390B1 (de) 1991-01-30

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