JPH0665002A - Attracting and feeding-stimulating agent for cockroach - Google Patents

Abstract

PURPOSE:To provide an agent containing a compound such as 5-indanol, 5- aminoindane or 3',4'-methylenedioxyphenol as an active ingredient, exhibiting a strong attracting and feeding-stimulating a action for various kinds of cockroaches, and effective for the control of the cockroaches. CONSTITUTION:The cockroach-attracting and feeding-stimulating agent comprises one or more kinds of compounds of the formula (R is amino, OH; X is methylene, O) (e.g. 5-indanol, 5-aminoindane, 3',4'-methylene dioxyphenol, 3',4'-methylenedioxyaniline) as an active ingredient. The compound of the formula exhibits a strong attracting action and a strong feeding action for many kinds of cockroaches, has a good fixing property, and further does not cause the deterioration of its activity even in the case of the coexistence of female and male cockroaches. Since the agent does not require the addition of starch, a saccharide, etc., on its production, the production cost of the agent is low, and the agent is convenient on its employment because of not requiring large formulations. Further, the active ingredient can add the fast-acting property to various conventional cockroach control agents.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a cockroach attractant and feeding stimulant.

[0002]

2. Description of the Related Art Cockroaches are one of the most well-known hygienic pests in the world, and in Japan, black cockroaches, Yamato cockroaches, American cockroaches, and German cockroaches are also known as home-living properties. Conventionally, as a substance having an attracting action against this, other sex pheromones obtained by extracting from feces and midgut of the American cockroach are known, and several kinds of monoterpenoid compounds and myristic acid, fatty acids such as palmitic acid and The esters thereof, tetralol naphthol (JP-A-61-69701), irisectramine alcohol (JP-A-61-72702),
Seed oils (JP-A-62-135403), phenol compounds (JP-A-63-96101) and the like are also known.

[0003]

However, in order to extract the sex pheromone, a large number of cockroaches are required, and since the sex pheromone is excitatory, it has an effect of collecting the cockroaches. Not only is it difficult to evoke and establish it, but its activity tends to be significantly reduced when males and females coexist (S. Takahashi, C. Kitamura: Appl. Ent. Zoo-l. 2 (3 ), 135-141 (1972)]. In addition, since fatty acids such as myristic acid and palmitic acid and their esters have a weak attracting activity against cockroaches, a considerable amount of concentration is required in the preparation, and, by themselves, they have no effect on colonization or feeding stimulation, In order to induce feeding stimuli, the addition of den powder and sugar was essential. Tetralol naphthol, phenolic compounds and irisectramine's alcohol were sufficiently active even at low concentrations and alone, and were useful without the addition of other additives, but bait formulations containing den powder and sugars, etc. On the contrary, there were cases where the effect was not fully utilized.

[0004]

The inventors of the present invention have conducted extensive studies to produce an effective cockroach attractant without the drawbacks of these conventional cockroach attractants.

[0005]

[Chemical 2]

The compound represented by the formula (wherein R represents an amino group or a hydroxyl group and X represents a methylene or an oxygen atom) may be used alone or in any of the preparations for many cockroach species. The present invention was completed by discovering that not only it has a strong attracting action and a feeding action and has good fixability, but the activity does not decrease even when males and females coexist. The present invention is an attractive feeding stimulant for cockroaches, which comprises a compound represented by formula (I) as an active ingredient.

Representative examples of the compounds represented by formula (I) of the present invention are shown in Table 1.

[0008]

[Table 1] Shown in.

This compound is a known compound described in the following documents or a compound which can be synthesized based on the documents. AHCook et al., J. Chem. Soc., 1930,2510 (synth dreiv
s) CAPanetta et al., J.Org.Chem ., 1961, 26 .4859 (synth) E.Haslam et al., J.Chem.Soc., 1955,827 JBHendrickson et al., J.Am.Chem. Soc., 1974, 96 , 778
(synth, ir)

The attractant / feeding stimulant of the present invention can be produced, for example, as follows. That is, the compound represented by the formula (I) is treated with a suitable solvent (eg, hydrophilic organic solvent such as acetone, methanol, ethanol, tetrahydrofuran, ethylene glycol, diethylene glycol, dimethylformamide, benzene, chloroform, ether, methylene chloride, A solution dissolved in a lipophilic organic solvent such as n-hexane may be impregnated into a suitable carrier (eg, filter paper, cardboard, non-woven fabric, cotton cloth, flannel) and dried to produce an attractant or feeding stimulant. I can. Further, the compound represented by the formula (I) is mixed in the pressure-sensitive adhesive or the resin, mixed with the insecticide in the pressure-sensitive adhesive or the resin, or mixed in the bait agent. We can manufacture attractive insecticidal sheets, the same plates and tapes, attractive bait agents, etc. In addition, an emulsifier, a dispersant, a penetrating agent, a suspending agent, a wetting agent, a spreading agent, an excipient, a stabilizer, etc. are added to the compound represented by the formula (I), and an oil agent,
It is possible to produce an attractant or feeding stimulant in the form of a wettable powder, a powder, a granule, a pill, a tablet, a spray, or the like.

[0011]

INDUSTRIAL APPLICABILITY The attractant and feeding stimulant of the present invention exhibits a strong attracting and feeding stimulating action on various cockroaches, and is extremely effective in exterminating cockroaches. Further, the attraction and feeding stimulant components of the present invention alone have a strong attraction to cockroaches, exhibit a feeding stimulating effect and also have a good fixing action, and it is necessary to add den powder, sugar and the like in the production of attracting feeding. Therefore, the attractant / feeding stimulant of the present invention has a low production cost and is convenient for use without increasing the size of the formulation. Further, the cockroach attracting and feeding stimulant component of the present invention can add fast-acting properties to each cockroach pesticide.

The effects of the attractant and feeding stimulant of the present invention will be specifically described below with reference to test examples.

Test Example 1 As test insects, a group of 100 male and female (1: 1) adults with a 1 month emergence of American cockroaches, black cockroaches, cockroaches, American cockroaches, black cockroaches, cockroaches, and German cockroaches was used as a group. Prepare 1 group each, 5-indanol, 5-aminoindane, 3 ', 4'
-(Methylenedioxy) phenol, 3 ', 4'-(methylenedioxy) aniline was used as a sample, and a
r-α-Tetralol and ar-β-Tetralol were used as controls. Filter paper with a diameter of 11 cm (Toyo Filter Paper No.
1) Two circles with a diameter of 3.5 cm are equidistantly arranged on top of each other, and each circle has an acetone solution of 30 μm containing 1.5 mg of the sample
1 and 30 μl of acetone as a blank were sufficiently air-dried to volatilize the solvent to prepare a test paper. Place one group of individual test insects in separate cages (35 x 30 x 18 cm polycarbonate transparent container) at 25 ° C.
After breeding and acclimatizing under the conditions of 12L-12D (12 hours light period-12 hours dark period), separate test papers were put therein. After a lapse of 24 hours, the test paper was collected and its feeding state was examined. The samples showed strong attraction and feeding effects on various cockroaches. The results are shown in Table 2.

[0013]

[Table 2]

Test Example 2 As test insects, a group of male adult cockroach, female adult dog, female larvae, male larvae, and female larvae of 100 heads each having a single sex and age, and male cockroach adult males, female adult worms, One group was prepared for each group consisting of 100 male and 25 female larvae, each having a different sex and age (hereinafter referred to as male and female coexisting group). (Adults mean one month after emergence, and larvae mean middle-aged larvae four months after hatching.) In addition, 5-indanol, 5-aminoindan, 3 ',
4 '-(methylenedioxy) phenol, 3', 4'-
(Methylenedioxy) aniline was used as a sample, and ar-α-tetralol and ar-β-tetralol were used as controls. Treatment was carried out according to Test Example 1, and the degree of food intake was examined in the case where the sex and age of the American cockroach were single and when both males and females coexist. The specimens showed specific attracting and feeding stimulatory effects on adult male and female larvae of the American cockroach. Also,
No decrease in activity was observed even when male and female coexisted. The results are shown in Table 3.

[0015]

[Table 3]

Test Example 3 As test insects, 100 adults of the American cockroach, one month after eclosion, were set as one group, and one group was prepared for each. Further, oleic acid, myristic acid, lauryl alcohol, pentadecanol, octyl alcohol, bornyl acetate, nerol, 2-hydroxy-1-naphthoic acid, decalin, naphthalene, tetralin, ac-α-tetralol, 5-
Indanol, 5-aminoindane, 3 ', 4'-(methylenedioxy) phenol, 3 ', 4'-(methylenedioxy) aniline, acetone and a (1: 1) mixture of this and sucrose as specimens Used as. ac-α-
Like tetralol, 5-indanol, 5-aminoindane, 3 ', 4'-(methylenedioxy) phenol, 3 ', 4'-(methylenedioxy) aniline can be used as adult cockroaches without adding sucrose. On the other hand, it showed a specific attraction and feeding stimulant action. The results are shown in Table 4.

[0017]

[Table 4]

Test Example 4 As test insects, 1 group of adult Cockroach cockroaches 1 month after emergence and 15 middle-aged larvae of Cockroach cockroach 4 months after hatching were prepared as a group, one group each. 5-indanol, 5-aminoindane, 3 ', 4'-(methylenedioxy) phenol, and 3 ', 4'-(methylenedioxy) aniline were used as samples, and at various concentrations according to Test Example 1. A circular test paper (diameter: 1 cm) impregnated with each sample was prepared. A circular test paper was placed on the bottom of a vinyl chloride cup having a diameter of about 8.5 cm and a height of about 10 cm coated with liquid paraffin inside, and one test insect was released. After the dark period of 12 hours, the test paper was collected and examined for food marks, and the amount that 50% of the test insects showed a reaction [BR
₅₀ (μg)] was determined. The results are shown in Table 5. * Note) This test was conducted in order to quantify the strength of the attractive feeding effect of the compound of the present invention.

[0019]

[Table 5]

Test Example 5 As test insects, 100 adult American cockroaches one month after emergence were set as one group, and each group was prepared. Also, 5
-Indanol, 5-aminoindan and sucrose were used as the samples, and the treatment was performed according to Test Example 1 except that the coating concentration was changed, and the activity of each sample was examined. The specimen showed much stronger feeding stimulant than sucrose. The results are shown in Table 6.

[0021]

[Table 6]

Test Example 6 Using 5-indanol or 5-aminoindane as a sample, a circular filter paper (Toyo filter paper) having a diameter of 1 cm was prepared according to Test Example 4.
An attractant was prepared by impregnating No. 1) with 1000 μg of each sample. Also, 75 parts of fish meal, 5 parts of maltose, L
-Slightly water was added to a mixture consisting of 5 parts of arabinose, 5 parts of oleic acid, and 10 parts of rice bran oil to knead to prepare a lump-shaped attractant of about 0.7 g.

As test insects, three groups of 50 adult larvae and 50 adult larvae were prepared for the American cockroach, Black cockroach, Yamato cockroach, German cockroach, and American cockroach.

Four rooms each having a size of about 6 tatami mats were prepared, and one week before the test was carried out, one group of test insects of different species was released, and sufficient food and water were provided. Actual exploitation 54-142679
Trap A in which the circular attractant is installed in the center of the sticky surface of the cockroach trap described in Japanese Patent Publication, Trap B in which the dumpling-like bait (0.7 g) is also installed in the center of the sticky surface, and nothing is set on the sticky surface. A set of traps C was placed in this room, and after 24 hours, the number of cockroaches captured in each trap was examined. The experiment was repeated 3 times, and the average value was used as the number of captures. The results are shown in Tables 7 and 8.

[0025]

[Table 7]

[Table 8]

Test Example 7

Table 9 shows the formulation of the sample bait.

[0028]

[Table 9]

The formulation of the control bait is shown in Table 10.

[0030]

[Table 10]

A dumpling-like specimen bait and a control bait having the above formulations were prepared by a conventional method.

As test worms, three groups of 30 adult larvae and 30 adult larvae were prepared for the American cockroach, Black cockroach, Yamato cockroach, German cockroach, and American cockroach.

Eight rooms each having a size of about 6 tatami mats were prepared, divided into two groups, and various test insects were released to each of the groups A and B from one week before the test was carried out, and the food and water were sufficiently fed. Oita. The sample bait prepared in Table 9 was placed in the room of group A, and the control bait prepared in table 10 was placed in the room of group B in the same amount at five locations, and the number of deaths after 5 days was examined. The results are shown in Table 11.

[0034]

[Table 11]

[0035]

EXAMPLES The present invention will be specifically described below with reference to examples.

Example 1 Approximately 200 ml of n-hexane was added to approximately 20 g of 5-indanol and sufficiently stirred for approximately 10 minutes with a stirrer to dissolve. A non-woven fabric having a width of 20 cm, a length of 50 cm and a thickness of 0.1 cm was uniformly impregnated with this solution using a dispenser, and then air-dried well until n-hexane was vaporized. This impregnated cloth was cut into a width of 0.5 cm and a length of 20 cm by a cutting machine to produce an attracting and feeding tape. This tape can be used by installing it in the center of the adhesive plate of a container-shaped cockroach trap.

Example 2 0.5 parts of 5-aminoindan, 100 parts of boric acid, 400 parts of soluble den powder, 400 parts of potatoden powder, 9 parts of wheat flour
A bait agent was manufactured by mixing 9.5 parts g and 500 parts of water and molding into an appropriate size.

Example 3 3 ', 4'-(methylenedioxy) phenol was added to 0.0
5 parts, white petrolatum 20 parts, phenotrothion 77.9
5 parts were mixed and applied to a polyethylene tape having a width of 5 cm and a length of 200 m. This is 5 cm wide and 20 c long
It was cut into m pieces to produce insecticidal tape.

Example 4 0.5 g of 3 ', 4'-(methylenedioxy) aniline was added to 200 ml of acetone and dissolved by stirring well. A circular filter paper (Toyo Filter Paper No. 1) having a diameter of 3 cm was impregnated with about 0.1 ml of this solution using a whole pipette, and then air-dried well until acetone was evaporated. A glass cylinder (diameter 13c) with a width of 5 cm coated with Vaseline
This impregnated filter paper was placed in a m, height 18 cm) to produce a simple cockroach trap.

Example 5 0.5 part of 5-aminoindan, 200 parts of natural rubber, 780 parts of tackifier, and 10 parts of antioxidant were well kneaded, and this was applied to a thick paper having a width of 9 cm and a length of 20 cm by a roll. Then, an attractive pressure-sensitive adhesive plate for a container-shaped cockroach trap was manufactured.

Example 6 2 parts of stearyl alcohol, 13.8 parts of white petrolatum and 1 part of sorbitan monostearate were dissolved and mixed, and 0.6 part of carboxyvinyl polymer and 13.8 parts of liquid paraffin heated to 60 ° C. were added. Mix to form Phase I. Further, 0.05 part of 5-indanol and 2 parts of pralethrin are mixed and dissolved with 40 parts of propylene glycol and 7 parts of polyoxyethylene sorbitan monostearate to form a phase II. After mixing Phase I and Phase II, add 22 parts of purified water to 20 parts of sugar.
Part and a solution in which 0.02 parts of sodium hydroxide were mixed and dissolved were added and further mixed to prepare a paste agent.

Example 7 0.1 part of 5-aminoindane, 3 parts of d-phenothrin,
5.5 parts of n-hexadecyl 2-ethylhexanoate,
72 parts of castor oil, 18 parts of beeswax and 4.5 parts of glycerol monostearate were dissolved and mixed to prepare a paste.

Example 8 A 10% acetone solution of 5-indanol was added to a thickness of 2.8 m.
After impregnating the pulp mat of No. m with air, it is air-dried until acetone is evaporated. This was cut into an appropriate size to produce an attracting mat.

Example 9 0.5 part of 5-indanol, 50 hydramethylnon
Part, soluble den powder 200 parts, potato den powder 150 parts,
599.5 parts of water were mixed and molded into an appropriate size to produce a bait agent.

Front page continued (72) Inventor Fumio Urushizaki 3-24-1, Takada, Toshima-ku, Tokyo Taisho Pharmaceutical Co., Ltd. (72) Inventor Haruo Shimamura 3-24-1, Takada, Toshima-ku, Tokyo Taisho Pharmaceutical Co., Ltd. In the company

Claims (1)

[Claims] 1. The formula: (In the formula, R represents an amino group or a hydroxyl group, and X represents a methylene or an oxygen atom.) At least one compound or a compound represented by the formula (1) is used as an active ingredient. Food stimulant.