JPH0548201B2 - - Google Patents

Description

[Detailed description of the invention]

INDUSTRIAL APPLICATION FIELD The present invention relates to an agent for attracting and stimulating feeding of American cockroaches. BACKGROUND OF THE INVENTION The American cockroach is the most well-known type of cockroach, distributed all over the world, and is the largest species of domestic cockroach in Japan. Conventionally, sex pheromones extracted from the feces and midgut of the American cockroach have been known as substances that have an attracting effect on this, as well as several monoterpenoid compounds (Japanese Patent Laid-Open No. 56-29502,
No. 56-30905, No. 56-30940, No. 56-79602,
56-79640, 56-87536, etc.), fatty acids such as myristic acid and palmitic acid, and their esters (Japanese Patent Publication No. 44-320). Problems to be Solved by the Invention However, extracting sex pheromones requires a large number of American cockroaches, and monoterpenoid compounds require a complicated synthesis process.
Because sex pheromones are excitatory, not only do they have a difficult time establishing themselves, but their activity tends to decrease significantly when males and females coexist. [S.
TAKAHASHI, C. KITAMURA: Appl.Ent.
Zool. 2(3), 133-141 (1972)] In addition, fatty acids such as myristic acid and valmitic acid and their esters have weak attracting activity to American cockroaches, and when used alone, they have no effect on colonization or stimulating feeding. , required the addition of starch and sugars. This not only increases the production cost of the attractant, but also increases the size of the attractant, making it inconvenient to use. Means for Solving the Problem The present inventors conducted intensive research to produce an effective cockroach attractant that does not have the drawbacks of these conventional cockroach attractants. The present invention was completed based on the discovery that not only does it have a strong attracting effect and a stimulating effect on feeding, it has good colonization properties, but its activity does not decrease even when males and females coexist.
The present invention is an agent for attracting and stimulating feeding of American cockroaches, which is characterized by containing irristectramine alcohol as an active ingredient. Irristectramine alcohol has the chemical name 3,7-dimethyl-10-isopropyl-2,6-
Cyclodecadien-1-ol, its chemical structure is It is expressed as Irristectramine alcohol can be obtained by (a) photoaddition reaction of methylcyclobutene and D-piperitone followed by thermolysis, (b) extraction from Verbesima Iatisquamata [F. Bohlman: Chem. Ber., 111 , 254-263
(1978)], (c) Iris tectorum Maxim can be obtained by reducing iris tectorum A, which is obtained from the seed oil of Iris tectorum Maxim, with LiAlH ₄ . Since only a very small amount can be obtained by methods (a) and (b), it is desirable to produce by method (c). As a result of various instrumental analyzes of iristectramine alcohol, its UV (EtOH) was 206n
m shows terminal absorption (ε6610). Its IR (KBr) is 3380, 1660, 1384, 1366,
It showed a characteristic absorption at 845 cm ^-1 . In the high-resolution mass spectrum, M ⁺ appeared at m/z222 (C ₁₅ H ₂₆ O). Also, ^1H -NMR (CCl ₄ , 60MHz)
The results were 0.95 and 0.97ppm, respectively.
3H, doublet, J = 6.6 Hz, indicating the presence of a methyl group at the end of the isopropyl group. The inducer and feeding stimulant of the present invention can be produced, for example, as follows. That is, iristectramine alcohol is mixed with a suitable solvent (e.g., a hydrophilic organic solvent such as acetone, methanol, ethanol, tetrahydrofuran, ethylene glycol, diethylene glycol, dimethylformamide; a parent solvent such as benzene, chloroform, ether, methylene chloride, n-hexane, etc. A solution dissolved in an oil-based organic solvent, etc. is transferred to a suitable carrier (e.g., paper, cardboard, nonwoven fabric, etc.).
It can be impregnated into cotton cloth, flannel, etc. and dried to produce an attractant and feeding stimulant. In addition, irristectramine can be mixed into alcohol adhesives, adhesives with insecticides, or bait agents, and can be used to attract adhesive boards, insect attraction sheets, tapes, and bait agents. etc. can be manufactured. In addition, emulsifiers, dispersants, penetrants, suspending agents, wetting agents, spreading agents, excipients, stabilizers, etc. are added to this compound to form oils, emulsions, wettable powders, powders, granules, and pills. , inducements in the form of tablets, sprays, etc.
A feeding stimulant can be produced. Effects Hereinafter, the effects of the inducer and feeding stimulant of the present invention will be specifically explained using test examples. Test example 1 The test insects were American cockroach, black cockroach,
Male and female (1:1) adults of the Yamato cockroach, Kowamon cockroach, Japanese cockroach, Japanese cockroach, and Japanese cockroach were taken one month after emergence.
Groups of 100 animals were prepared, and irristectramine alcohol was used as the sample. Evenly spaced on paper (Toyo Paper No. 2) with a diameter of 11 cm
Set up two ^3.5cm2 circles, and place only the sample in each circle.
Apply a solution containing 1000 μg and 1000 μg of acetone.
This was sufficiently air-dried to evaporate the solvent to prepare a test paper. Each group of test insects was placed in a separate cage (35 x 30 x 18 cm transparent polycarbonate container) and reared at 25°C under conditions of 12L-12D (12 hours light - 12 hours dark). After getting used to it, I put a separate test paper in each one. After 24 hours, the test paper was collected and its feeding status was examined. The specimen is a specific attractant for the American cockroach,
It showed a feeding stimulant effect. The results are shown in Table 1.

[Table] Test Example 2 Test insects were a single group of 100 male American cockroaches, 100 same female adults, 100 same male larvae, and 100 same female larvae, and a single group of male American cockroaches and 100 same female larvae. A necessary number of groups (hereinafter referred to as male-female coexistence groups) consisting of 100 larvae each consisting of 25 same-male larvae and 25 same-female larvae were prepared in which larvae of different sexes and instars coexisted (hereinafter referred to as male-female coexistence group). (Adults refer to those that have passed one month after emergence, and larvae refer to middle-instar larvae that have passed four months after hatching.) Irristectramine alcohol was also used as a sample. The treatment was carried out in accordance with Test Example 1, and the degree of feeding was examined for the sex and age of the American cockroach when it was single and when both sexes coexisted. The sample exhibited specific attracting and feeding stimulating effects on male adult American cockroaches and their larvae. Furthermore, no decrease in activity was observed even when both sexes coexisted. The results are shown in Table 2.

[Table] Test Example 3 As test insects, 100 adult male American cockroaches one month after emergence were used as one group, and the required number of groups were prepared. Also, oleic acid, myristic acid, lauryl alcohol, pentadecanol, octyl alcohol, bornyl acetate, nerol, 2-hydroxy-
1-naphthoic acid, decalin, naphthalene, tetralin, iristectramine alcohol, acetone, and a mixture of these and sucrose (1:1) were used as specimens. The samples were treated in accordance with Test Example 1, and after a 12-hour dark period, the test paper was collected and the feeding state of each sample was examined. Iristectramine alcohol exhibited specific attracting and feeding stimulating effects on male American cockroaches even without the addition of sucrose. The results are shown in Table 3.

【table】

[Table] Synonymous with evaluation.
Test Example 4 As test insects, the required number of adult male American cockroaches that had elapsed one month after emergence and male middle-instar larvae that had elapsed four months after hatching were prepared. Further, circular test papers (1 cm in diameter) impregnated with each sample at various concentrations were prepared in accordance with Test Example 1 using iristectramine alcohol as a sample. Approximately 8.5 in diameter with liquid varafine applied on the inside.
A circular test paper was placed at the bottom of a vinyl chloride cup with a height of approximately 10 cm, and one test insect was released. After a 12-hour dark period, the test paper was collected and the feeding marks were examined to determine the amount [BR ₅₀ (μg)] at which 50% of the test insects reacted. The results are shown in Table 4.

[Table] Test Example 5 The required number of groups were prepared as test insects, each consisting of 100 male American cockroaches one month after emergence. In addition, test example 1 was conducted using irristectramine alcohol and sucrose as samples, and the application concentration was changed.
The activity of each sample was examined. The sample showed much stronger feeding stimulation than sucrose. The results are shown in Table 5.

[Table] Test example 6 (1) Irristectramine alcohol was used as the sample,
According to Test Example 4, attractants were prepared by impregnating 1000 μg of each sample into circular papers (Toyo Paper No. 2) with a diameter of 1 cm. Further, a small ball-shaped attractant bait was prepared by adding some water to a mixture consisting of 75 parts of fish meal, 5 parts of maltose, 5 parts of L-arabinose, 5 parts of oleic acid, and 10 parts of rice bran oil and kneading it. (2) In a room with an area of about 6 tatami mats, 60 adult male American cockroaches, one month after emergence, were placed one week before the test.
I released the head and kept it well fed and watered. Trap A is a cockroach trap described in Japanese Utility Model Application Publication No. 54-142679, in which a circular attractant is placed in the center of the adhesive surface; Trap B is also a trap B in which a dumpling-shaped attractant bait (0.7 g) is placed in the center of the adhesive surface; A set of traps C with nothing placed on the sticky surface were placed in this room, and after 24 hours, the number of cockroaches captured by each trap was determined. The experiment was repeated three times, and the average value was taken as the number of captured insects. The results are shown in Table 6.

[Table] Effects of the Invention The attractant and feeding stimulant of the present invention exhibits specific attracting and feeding stimulating uses for male American cockroaches.
It is extremely effective in exterminating American cockroaches because it selectively kills only males and prevents male fertilization. In addition, the attracting and feeding stimulating ingredient of the present invention shows a strong attracting and feeding stimulating effect on male American cockroaches even when used alone, and also has a good fixation effect. Therefore, the attractant and feeding stimulant of the present invention has a low production cost and is convenient to use without requiring a large dosage form. Examples Hereinafter, the present invention will be specifically described with reference to Examples. Example 1 Approximately 200 ml of 1 g of irristectramine alcohol
of n-hexane, and was thoroughly stirred with a stirrer for about 10 minutes to dissolve. A nonwoven fabric having a width of 20 cm, a length of 50 cm, and a thickness of 0.1 cm was uniformly impregnated with this solution using a dispenser, and then thoroughly air-dried until the n-hexane was volatilized. This impregnated cloth is cut into a width of 0.5 cm and a length of 20 cm using a cutting machine.
It was cut into cm to produce an attraction and feeding stimulation tape. This tape can be used by placing it on the center of the adhesive plate of a container-shaped cockroach trap. Example 2 Iristectramine alcohol 10g, boric acid
100g, soluble starch powder 150g, potato starch powder 150g
g and 590 g of water were mixed and molded into an appropriate size to produce a bait agent. Example 3 4 g of iristectramine alcohol, 20 g of white petrolatum, and 76 g of permethrin were mixed and applied to a polyethylene tape having a width of 5 cm and a length of 200 m. This was cut into pieces 5 cm wide and 20 cm long to produce insecticidal tape. Example 4 Approximately 200ml of 1g of irristectramine alcohol
of acetone and shake well to dissolve. Approximately 0.1 ml of this solution was impregnated into circular paper (Toyo Paper No. 2) with a diameter of 3 cm using a whole pipette, and then air-dried thoroughly until the acetone evaporated. A simple cockroach trap was prepared by placing a sheet of impregnated paper in a glass cylinder (diameter 13 cm, height 18 cm) whose inside was coated with Vaseline to a width of 5 cm. Example 5 Iristectramine alcohol 10g, natural rubber
200 g of the tackifier, 780 g of the tackifier, and 10 g of the antioxidant were thoroughly kneaded and coated on a cardboard roll with a width of 9 cm and a length of 20 cm to produce an attraction adhesive plate for a container-shaped cockroach trap.

Claims (1)

[Claims] 1 3,7-dimethyl-10-isopropyl-2,
An agent for attracting and stimulating feeding of American cockroaches, characterized by containing 6-cyclodecadien-1-ol as an active ingredient.