JP2988005B2 - Cockroach Attraction, Feeding Stimulant - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cockroach attractant / feeding stimulant.

[0002]

2. Description of the Related Art Cockroaches are one of the most well-known sanitary pests in the world. Even in Japan, black cockroaches, Yamato cockroaches, American cockroaches, German cockroaches, and the like are known as home dwellings. Conventionally, sex pheromones obtained by extracting from the cockroach feces and the mid-gut are known as substances having an attracting effect on this, as well as several monoterpenoid compounds and fatty acids such as myristic acid and palmitic acid. Its esters, tetralol naphthol (Japanese Patent Application Laid-Open No. 61-69701), iris pectramine alcohol (Japanese Patent Application Laid-Open No. 61-72702),
Seed oil (JP-A-62-135403), phenolic compounds (JP-A-63-96101) and the like are also known.

[0003]

However, extracting a sex pheromone requires a large number of cockroaches, and since sex pheromone is excitable, it has an effect of assembling cockroaches. Not only is it difficult to evoke and settle, but its activity also tends to decrease significantly when both sexes coexist (S. Takahashi, C. Kitamura: Appl. Ent. Zoo-l.2 (3. ), 135-141 (1972)]. In addition, fatty acids such as myristic acid and palmitic acid and their esters require a considerable amount of concentration in preparations because of their low attracting activity against cockroaches, and alone do not have an effect of fixing or stimulating feeding, Addition of starch and sugars was indispensable to induce feeding stimuli. With tetralol naphthol, phenolic compounds and iris techtramins alcohol, it was active even at low concentrations alone, and was useful without adding other additives. In some cases, the effect was not fully utilized.

[0004]

The present inventors have conducted intensive studies to produce an effective cockroach attractant which does not have the drawbacks of these conventional cockroach attractants.

[0005]

Embedded image

(Wherein, R represents an amino group or a hydroxyl group, and X represents a methylene or oxygen atom). The compound represented by the formula The present invention has been found to show not only a strong attraction effect and a feeding effect, but also a good fixation property, and that no activity is reduced even when both sexes coexist. The present invention is a cockroach attracting and feeding stimulant comprising a compound represented by the formula (I) as an active ingredient.

Typical examples of the compound represented by the formula (I) of the present invention are shown in Table 1.

[0008]

[Table 1] Shown in

The present compound is a known compound described in the following literature or a compound that can be synthesized based on the literature. AHCook et al., J.Chem.Soc., 1930,2510 (synth dreivs) CAPanetta et al., J.Org.Chem., 1961, 26 .4859 (synth) E.Haslam et al., J.Chem. Soc., 1955, 827 JB Hendrickson et al., J. Am. Chem. Soc., 1974, 96 , 778 (synth, ir)

The attractant / feeding stimulant of the present invention can be produced, for example, as follows. That is, a compound represented by the formula (I) is converted into a suitable solvent (for example, a hydrophilic organic solvent such as acetone, methanol, ethanol, tetrahydrofuran, ethylene glycol, diethylene glycol, dimethylformamide, benzene, chloroform, ether, methylene chloride, A solution dissolved in a lipophilic organic solvent such as n-hexane or the like is impregnated with a suitable carrier (eg, filter paper, cardboard, nonwoven fabric, cotton cloth, flannel, etc.) and dried to produce an attractant or eating stimulant. I can do it. Further, the compound represented by the formula (I) may be mixed into an adhesive or resin, mixed with an insecticide into an adhesive or resin, or mixed into a bait, etc., to thereby attract each of the adhesive plates. , Attractant insecticide sheet, plate and tape, attractant bait, etc. In addition, an emulsifier, a dispersant, a penetrant, a suspending agent, a wetting agent, a spreading agent, an excipient, a stabilizer, and the like are added to the compound represented by the formula (I).
Attracting and feeding stimulants in the form of wettable powders, powders, granules, pills, tablets, sprays and the like can be produced.

[0011]

The attractant / feeding stimulant of the present invention has a strong attractant / feeding stimulating action on various cockroaches, and is remarkably effective in controlling cockroaches. In addition, the attractant and feeding stimulating component of the present invention shows a strong attractant and feeding stimulating effect on cockroaches alone and also has a good fixation effect, and it is necessary to add starch powder, sugar and the like in the production of attractant food. Therefore, the attractant / feeding stimulant of the present invention is low in production cost and convenient to use without increasing the size of the dosage form. In addition, the cockroach-inducing and feeding stimulating components of the present invention can add quick efficacy to each cockroach repellent.

Hereinafter, the effects of the attractant and feeding stimulant of the present invention will be specifically described with reference to test examples.

Test Example 1 As test insects, a group of 100 male and female (1: 1) adult cockroaches, one-month-old cockroaches, black cockroaches, brown cockroaches, brown cockroaches, brown cockroaches, and brown cockroaches, each having a one-month eclosion of one month. Prepare 5 groups of 5-indanol, 5-aminoindane, 3 ', 4'
-(Methylenedioxy) phenol, 3 ', 4'-(methylenedioxy) aniline as a sample,
r-α-tetralol and ar-β-tetralol were used as controls. 11cm diameter filter paper (Toyo Filter Paper No.
1) Two circles of 3.5 cm in diameter are provided at equal intervals on the top, and each circle contains 30 mg of an acetone solution containing only 1.5 mg of a sample.
1 and 30 μl of acetone as a blank were sufficiently air-dried to evaporate the solvent to prepare test paper. Separate test insects were placed in separate cages (transparent 35 x 30 x 18 cm polycarbonate containers), each group at 25 ° C,
After breeding and acclimatizing under the conditions of 12L-12D (12 hours light period-12 hours dark period), separate test papers were put into each. After a lapse of 24 hours, the test paper was collected and its feeding state was examined. The samples showed strong attraction and feeding effects on various cockroaches. Table 2 shows the results.

[0013]

[Table 2]

Test Example 2 Male and female adults of the cockroach, the female adult, the male larva, and the female larva, each having a single sex and age of 100, were used as test insects. A group of 25 male and female larvae each having a total of 100 larvae of different sex and age (hereinafter referred to as a male and female coexisting group) was prepared. (Adults refer to those one month after eclosion, and larvae refer to middle-aged larvae four months after hatching.)
Also, 5-indanol, 5-aminoindane, 3 ′,
4 '-(methylenedioxy) phenol, 3', 4'-
(Methylenedioxy) aniline was used as a sample, and ar-α-tetralol and ar-β-tetralol were used as controls. The treatment was carried out in accordance with Test Example 1, and the degree of feeding was examined in the case of the sex and age of the cockroach being single and in the case where both sexes coexist. Specimens showed specific attraction and feeding stimulatory effects on adult and male larvae of the cockroach. Also,
No decrease in activity was observed even when both sexes were present. Table 3 shows the results.

[0015]

[Table 3]

Test Example 3 As test insects, a group of 100 cockroach adults, one month after eclosion, was prepared. Also, oleic acid, myristic acid, lauryl alcohol, pentadecanol, octyl alcohol, bornyl acetate, nerol, 2-hydroxy-1-naphthoic acid, decalin, naphthalene, tetralin, ac-α-tetralol, 5-
Indanol, 5-aminoindane, 3 ', 4'-(methylenedioxy) phenol, 3 ', 4'-(methylenedioxy) aniline, acetone, and a (1: 1) mixture thereof with sucrose Used as ac-α-
Like tetralol, 5-indanol, 5-aminoindan, 3 ', 4'-(methylenedioxy) phenol, and 3 ', 4'-(methylenedioxy) aniline can be used for adult cockroaches without the addition of sucrose. On the other hand, it showed a specific attraction and feeding stimulating effect. Table 4 shows the results.

[0017]

[Table 4]

Test Example 4 As test insects, adult cockroaches, one month old after eclosion, and 15 middle-aged cockroaches, four months old after hatching, were prepared as one group. Using 5-indanol, 5-aminoindane, 3 ′, 4 ′-(methylenedioxy) phenol and 3 ′, 4 ′-(methylenedioxy) aniline as samples, at various concentrations according to Test Example 1. Circular test papers (1 cm in diameter) each impregnating each specimen were prepared. A circular test paper was placed on the bottom of a vinyl chloride cup having a diameter of about 8.5 cm and a height of about 10 cm coated with liquid paraffin on the inside, and one test insect was released. After the dark period of 12 hours, the test paper was collected and examined for blemishes.
₅₀ (μg)]. Table 5 shows the results. * Note) This test was performed to quantify the strength of the induced feeding effect of the compound of the present invention.

[0019]

[Table 5]

Test Example 5 As test insects, 100 adult cockroaches, one month after eclosion, were divided into one group, and each group was prepared. Also, 5
-Indanol, 5-aminoindan and sucrose were used as samples, and treated in the same manner as in Test Example 1 except that the coating concentration was changed, and the activity of each sample was examined. Specimens showed much stronger feeding stimuli than sucrose. Table 6 shows the results.

[0021]

[Table 6]

Test Example 6 Circular filter paper having a diameter of 1 cm (Toyo Filter Paper) was prepared according to Test Example 4 using 5-indanol or 5-aminoindane as a sample.
An attractant in which No. 1) was impregnated with 1000 μg of each sample was prepared. In addition, 75 parts of fish meal, 5 parts of maltose, L
-A mixture of 5 parts of arabinose, 5 parts of oleic acid, and 10 parts of rice bran oil was added with a little water and kneaded to prepare a small dumpling attractant of about 0.7 g.

As test insects, three groups each consisting of 50 adults and 50 larvae of cockroaches, black cockroaches, Yamato cockroaches, German cockroaches, and European cockroaches were prepared.

Four rooms each having a size of about 6 tatami mats were prepared, and a group of test insects of a different species was released from each group one week before the test, and food and water were sufficiently provided. 54-142679
No. 5,078,064, trap A in which the circular attractant is installed at the center of the sticky surface of the cockroach trap described in Japanese Patent Application Publication No. H11-27139, trap B in which the dumpling-like bait (0.7 g) is installed in the center of the sticky surface, and nothing is installed on the sticky surface. One set of traps C was placed in this room, and after 24 hours, the number of cockroaches captured by each trap was examined. The experiment was repeated three times, and the average value was used as the number of catches. The results are shown in Tables 7 and 8.

[0025]

[Table 7]

[Table 8]

Test Example 7

Table 9 shows the formulation of the sample bait.

[0028]

[Table 9]

The formulation of the control bait is shown in Table 10.

[0030]

[Table 10]

A dumpling sample bait and a control bait of the above formulation were prepared by a conventional method.

As test insects, three groups each consisting of 30 adult larvae and 30 larvae were prepared for cockroaches, black cockroaches, Yamato cockroaches, German cockroaches, and European cockroaches.

Eight rooms each having a size of about 6 tatami mats were prepared, divided into two groups, and various test insects were released to each of the groups A and B one week before the test was performed, and sufficient food and water were given. Oita. The sample baits prepared in Table 9 were placed in the room of Group A, and the control baits prepared in Table 10 were placed in the same amount in five places in the room of Group B, and the number of deaths after 5 days was examined. Table 11 shows the results.

[0034]

[Table 11]

[0035]

The present invention will be specifically described below with reference to examples.

Example 1 About 200 ml of n-hexane was added to about 20 g of 5-indanol, and dissolved by sufficiently stirring for about 10 minutes with a stirrer. This solution was uniformly impregnated with a dispenser into a nonwoven fabric having a width of 20 cm, a length of 50 cm, and a thickness of 0.1 cm, and was air-dried until n-hexane was volatilized. This impregnated cloth was cut into a width of 0.5 cm and a length of 20 cm by a cutting machine to produce an attracting and feeding stimulating tape. This tape can be used by being installed in the center of the adhesive plate of a cockroach trap in a container shape.

Example 2 0.5 part of 5-aminoindane, 100 parts of boric acid, 400 parts of soluble starch powder, 400 parts of potato powder, 9 parts of wheat flour
9.5 parts g and 500 parts of water were mixed and formed into an appropriate size to produce a bait.

Example 3 3 ', 4'-(Methylenedioxy) phenol was added to 0.0
5 parts, white vaseline 20 parts, phenothrothion 77.9
Five parts were mixed and applied to a polyethylene tape having a width of 5 cm and a length of 200 m. This is 5cm wide and 20c long
m to produce insecticidal tapes.

Example 4 0.5 g of 3 ', 4'-(methylenedioxy) aniline was added to 200 ml of acetone and dissolved with good stirring. About 0.1 ml of this solution was impregnated into a 3 cm-diameter circular filter paper (Toyo Filter Paper No. 1) using a whole pipette, and air-dried well until acetone was volatilized. A glass cylinder coated with petrolatum to a width of 5cm (diameter 13c)
m, a height of 18 cm), one sheet of this impregnated filter paper was put into it to produce a simple cockroach trap.

Example 5 0.5 part of 5-aminoindane, 200 parts of natural rubber, 780 parts of a tackifier and 10 parts of an antioxidant were kneaded well, and the mixture was applied to a cardboard having a width of 9 cm and a length of 20 cm by a roll. Then, an attracting adhesive plate for a container-shaped cockroach trap was manufactured.

Example 6 2 parts of stearyl alcohol, 13.8 parts of white petrolatum and 1 part of sorbitan monostearate were dissolved and mixed, and 0.6 part of a carboxyvinyl polymer and 13.8 parts of liquid paraffin heated to 60 ° C. were added. Mix to form Phase I. Further, 0.05 part of 5-indanol and 2 parts of praretrin are mixed and dissolved with 40 parts of propylene glycol and 7 parts of polyoxyethylene sorbitan monostearate to form a phase II. After mixing phases I and II, sugar 20 was added to 22 parts of purified water.
And a solution prepared by mixing and dissolving 0.02 parts of sodium hydroxide and 0.02 part of sodium hydroxide were added and further mixed to prepare a paste.

Example 7 0.1 part of 5-aminoindane, 3 parts of d-phenothrin,
5.5 parts of n-hexadecyl 2-ethylhexanoate,
A paste was prepared by dissolving and mixing 72 parts of castor oil, 18 parts of beeswax and 4.5 parts of glycerol monostearate.

Example 8 A 10% solution of 5-indanol in acetone was 2.8 m thick.
m, and then air-dried until acetone evaporates. This was cut into a suitable size to produce an invitation mat.

Example 9 0.5 part of 5-indanol, hydramethylnon 50
Parts, soluble starch powder 200 parts, potato powder 150 parts,
599.5 parts of water was mixed and formed into an appropriate size to produce a bait.

──────────────────────────────────────────────────続 き Continuing on the front page (72) Fumio Urushizaki 3-24-1, Takada, Toshima-ku, Tokyo Taisho Pharmaceutical Co., Ltd. (72) Haruo Shimamura 3-24-1, Takada, Toshima-ku, Tokyo Taisho Pharmaceutical (58) Investigated field (Int.Cl. ⁶ , DB name) A01N 31/08 A01N 33/06 A01N 43/12 A01N 43/30 CA (STN)

Claims (1)

(57) [Claims] (1) Formula (1) (In the formula, R represents an amino group or a hydroxyl group, and X represents a methylene or oxygen atom.) At least one compound represented by the formula (I) is used as an active ingredient. Food stimulants.