JPH0597627A - Corneoplug remover - Google Patents

Abstract

PURPOSE:To provide the subject remover capable of suppressing the conspicuousness of pares of the skin owing to effectively removing the corneoplug formed in the pores, thus enabling the pores to be kept clean, also causing no skin injuries. CONSTITUTION:The objective remover contain, as active ingredient, a polymeric compound having salt-forming group selected from carboxyl group, sulfonate residue, sulfate residue, phosphate residue, nitrate residue, amino group and ammonium group (pref. 10000-3000000, esp. 100000-1000000 in molecular weight), e.g. polymethacryloyloxymethyl succinate, polymethacrylamidopropyl trimethylammonium chloride. This remover is coated or applied on the skin and dried, and the resulting film is then peeled off the skin, thus removing corneoplug. In case the salt-forming group has not been ionized, it is preferable that the group be ionized by neutralizing it with an acid or base.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a keratin plug removing agent which can satisfactorily remove keratin plugs formed in pores.

[0002]

2. Description of the Related Art Conspicuous pores are one of the top problems in women's skin troubles recently, which is one of the top problems. This is largely due to the horn plug formed in the pores. The keratin plug is keratinized together with sebum and contains keratin and is clogged in the pores. If left unattended, not only the pores are conspicuous but also various skin problems occur. Therefore, it is preferable to remove the keratin plug from the viewpoint of beauty and skin health.

However, the keratin plug cannot be sufficiently removed by the commonly used face wash and makeup remover. On the other hand, peel-off type pack agents are applied on the skin, dried and then peeled off from the skin. As film-forming agents used therefor, polyvinyl alcohol, polyvinyl pyrrolidone and the like are used. However, those containing these nonionic polymers as the main components are not sufficient for removing stains on the pores that are difficult to remove, and show little effect particularly for removing horn plugs.

Therefore, a keratin plug removing agent that can effectively remove keratin plugs has been desired.

[0005]

In view of such circumstances, the inventors of the present invention have conducted diligent research and as a result, found that a keratin plug removing agent containing a synthetic polymer having a salt-forming group is effective for keratin plug and The present invention has been completed by finding that stains should be removed.

[0006] That is, the present invention provides a keratin plug removing agent characterized by containing a synthetic polymer compound having a salt-forming group.

The salt-forming group of the polymer compound used in the present invention is not particularly limited as long as it is a group that forms a salt in the presence of an acid or a base, and any of anionic, cationic and zwitterionic groups can be used. May be Specific examples of such a salt-forming group include a carboxyl group, a sulfonic acid residue, a sulfuric acid residue, a phosphoric acid residue, a nitric acid residue, an amino group and an ammonium group. These groups are 2 in one compound
More than one species may be included.

It is aesthetically preferable that these polymer compounds are water-soluble, but they may be cloudy.

Specific examples of such high molecular compounds include natural or semisynthetic compounds such as mucopolysaccharides hyaluronic acid, hyaluronic acid Na, chondroitin sulfate Na; hemicelluloses alginic acid, sodium alginate, ammonium alginate, carboxy. Methyl cellulose Na salt,
Examples thereof include carboxymethylamylose, and synthetic ones are more preferable. As synthetic ones, one or two or more kinds of the following monomers are polymerized, or these monomers and an aliphatic carboxylic acid such as vinyl acetate. Vinyl ester, (meth) acrylic acid ester such as methyl methacrylate, alkyl vinyl ether such as methyl vinyl ether, N-vinyl cyclic amide such as N-vinylpyrrolidone, and other general non-salt-forming groups such as styrene and alkyl-substituted styrene. And a mixture of these polymers.

Anionic: unsaturated carboxylic acid monomers such as acrylic acid (AA), methacrylic acid (MA), maleic acid, itaconic acid, etc. or their anhydrides or their salts; styrenesulfonic acid, 2-acrylamido-2- Unsaturated sulfonic acid monomers such as methylpropanesulfonic acid (AMPS) or salts thereof; unsaturated phosphoric acid monomers such as vinylphosphonic acid and acid phosphoxyethyl (meth) acrylate.

Cationic: (meth) acrylic acid having a dialkylamino group such as dimethylaminoethyl acrylate (DMAEA), dimethylaminoethyl methacrylate (DMAEMA), dimethylaminopropyl acrylamide (DMAPAAm) and dimethylaminopropyl methacrylamide (DMAPMAAm). Esters or (meth) acrylamides; styrenes having a dialkylamino group such as dimethylaminostyrene (DMASt) and dimethylaminomethylstyrene (DMAMSt); vinylpyridines such as 4-vinylpyridine and 2-vinylpyridine; or these Quaternized with a known quaternizing agent such as alkyl halide, benzyl halide, alkyl or aryl sulfonic acid, or dialkyl sulfate.

Zwitterionic: N- (3-sulfopropyl)
-N-acryloyloxyethyl-N, N-dimethylammonium betaine, N- (3-sulfopropyl) -N
-Metacroylamidopropyl-N, N-dimethylammonium betaine, N- (3-carboxymethyl) -N
-Metacroylamidopropyl-N, N-dimethylammonium betaine, N- (3-sulfopropyl) -N-
Methacryloyloxyethyl-N, N-dimethylammonium betaine, N-carboxymethyl-N-methacryloyloxyethyl-N, N-dimethylammonium betaine.

When the salt-forming groups of these polymer compounds are not ionized, existing acids such as hydrochloric acid,
Inorganic salts such as sulfuric acid; organic acids such as acetic acid, propionic acid, lactic acid, succinic acid, glycolic acid, or bases, tertiary amines such as trimethylamine and triethylamine; neutralization with ammonia, sodium hydroxide, etc., and ionization Preferably.

Further, among these polymer compounds, one having one or two or more of the cationic monomers is polymerized as a polymer having excellent low irritation to the skin and high effect of removing keratin plug. And copolymers of these monomers with zwitterionic monomers and other general monomers having no salt-forming group, and further, mixtures of these polymers.

Among the cationic monomers, dimethylaminoethyl acrylate (D
MAEA), dimethylaminoethyl methacrylate (DMAEM
A), dimethylaminopropyl acrylamide (DMAPAAm)
, Dimethylaminopropyl methacrylamide (DMAPMAA
(meth) acrylic acid ester or (meth) acrylamide having a dialkylamino group such as m) or a known quaternizing agent such as alkyl halide, benzyl halide, alkyl or aryl sulfonic acid or dialkyl sulfate. A quaternized product can be used. Of these, dimethylaminoethyl methacrylate (D
MAEMA) and its quaternary compound; quaternary compound of dimethylaminopropyl methacrylamide (DMAPMAAm), or a polymer of one or more of these monomers, or one or more of these monomers and Copolymers with monomers or mixtures thereof are preferred.

The molecular weight of these polymer compounds is
Those in the range of 10,000 to 1,500,000 are preferable, and particularly 100,000 to
One million is preferable. When the molecular weight is less than 10,000, the strength of the film formed is insufficient, the tension on the skin is weakened, and the film is easily torn when peeled off.
Manufacturing more than 10,000 is difficult.

The amount of the above-mentioned polymer compound used in the keratin plug removing agent of the present invention is 0.01 to 70% by weight, particularly 5 to 40% by weight.
It is preferable that

The above-mentioned synthetic polymer compound is used by dissolving it in a solvent, and this solvent is not particularly limited as long as it can stably dissolve the polymer compound and is safe for the skin. Water, ethanol, isopropyl alcohol (IPA) and the like can be mentioned. The blending amount of this solvent may be appropriately determined depending on the polymer compound, the optional component and the dosage form, but is generally 30 to 99.99% by weight, particularly 60 to
95% by weight is preferred.

The keratin plug removing agent of the present invention contains, in addition to the above components,
Ingredients commonly used in cosmetics, such as ethylene glycol, diethylene glycol, triethylene glycol, higher polyethylene glycols, propylene glycol, dipropylene glycol, higher polypropylene glycols, 1,3-butylene glycol, 1,4 -Butylene glycols such as butylene glycol, glycerin, diglycerin, and more polyglycerins, sorbitol, mannitol, xylitol, sugar alcohols such as maltitol, ethylene oxide of glycerins (hereinafter abbreviated as EO), propylene oxide ( Hereinafter, abbreviated as PO) adduct, EO of sugar alcohols,
PO adducts, monosaccharides such as galactose, glucose and fructose and their EO, polysaccharides such as PO adducts, maltose and lactose and polyhydric alcohols such as EO and PO adducts;
Hydrocarbons such as liquid paraffin, squalane, petrolatum and solid paraffin, natural oils such as olive oil, jojoba oil, evening primrose oil, coconut oil and beef tallow, isopropyl myristate, cetyl isooctanoate, ester oils such as neopentyl glycol dicaprate , Silicone oils such as methyl silicone and methyl phenyl silicone, oily components such as higher fatty acids such as isostearic acid and oleic acid; POE alkyl ethers, POE branched alkyl ethers, POE sorbitan esters, POE glycerin fatty acid esters, POE hydrogenated castor oil, sorbitan Surfactants such as esters, glycerin fatty acid esters, polyglycerin fatty acid esters;
Vitamins, antiphlogistics, bactericides, activators, UV absorbers and other agents; montmorillonite, saponite, hectorite,
Water-swelling viscosity minerals such as bee gum, kunivia, smecton; Synthesis of carrageenan, xanthan gum, sodium alginate, pullulan, methyl cellulose, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose and other polysaccharides, carboxyvinyl polymer, polyvinylpyrrolidone, polyvinyl alcohol, etc. Other macromolecules such as macromolecules; extender pigments such as titanium oxide, kaolin, mica, sericite, zinc white, talc, etc., pigments such as polymer powders such as polymethylmethacrylic acid, nylon powder, etc. It can be appropriately blended within a range that does not impair the effect. Of these ingredients,
When an oily component is blended, the peel strength of the film formed during drying can be adjusted, and the film can be peeled satisfactorily without irritating the skin. Further, it is preferable to add the polyhydric alcohol in an amount of 0.01 to 50% by weight based on the total composition.

The keratin plug removing agent of the present invention may be used as it is, applied to the nose, forehead or chin portion having keratin plugs and peeled off after drying, or may be woven with cotton cloth, soft cloth, tetron, nylon or the like. It may be applied as a poultice on a cloth or a plastic sheet.

[0021]

EFFECTS OF THE INVENTION When the keratin plug removing agent of the present invention is used, keratin plugs are effectively removed, so that conspicuous pores are suppressed, the pores can be kept clean, and the skin is not damaged. ..

[0022]

The present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.

Example 1 Using the polymers shown in Table 1, a keratin plug removing agent was prepared according to the following pack formulation. Add 0.1 ml / cm ² to the panel after washing this
Was applied, and the mixture was left for 30 minutes at 25 ° C. and 50% humidity, and peeled off. From this, the keratin plug removal rate was calculated by the following formula and evaluated. The results are shown in Table 1.

[0024]

[Equation 1]

Evaluation: ◯: The removal rate of keratin plug exceeds 20%. Δ: The removal rate of keratin plug is 5 to 20%. X: Removal rate of keratin plug is less than 5%.

Pack prescription: Polymer 15-20 (wt%) Glycerol 5 HCO60 (Polyoxyethylene hydrogenated castor oil 60EO added) 1 Ethanol 5 Fragrance 0.5 Preservative Suitable amount Purified water 68.5-73.5 Total 100.0

[0027]

[Table 1]

Example 2 The polymers in Table 2 were used to evaluate the removal rate of keratotic plugs and the pain during peeling. Evaluation method: The polymer in Table 2 was made into a 20 to 30 wt% aqueous solution, which was applied to a face-washed panel at 0.1 ml / cm ² , left at 25 ° C. and 50% humidity for 30 minutes and then peeled off. The keratin plug removal rate was determined in the same manner as in Example 1. (Square plug removal rate) Less than 5%: × 5 to 19%: △ 20 to 34%: ○ 35% or more: ◎ (Pain when peeling) Slight pain: ＋ Slight pain: ++

[0029]

[Table 2]

Example 3 A keratin plug removing agent having the following composition was produced. Polymethacryloyloxytrimethylammonium chloride (QDM) (Molecular weight 400,000) 27.0 (wt%) Sorbitol 3.0 Sericite 3.0 Ethanol 5.0 Preservative Appropriate amount Water balance

Example 4 A keratin plug removing agent having the following composition was produced. Polymethacryloyloxytrimethylammonium chloride (QDM) (Molecular weight 250,000) 27.0 (wt%) Polyoxyethylene hydrogenated castor oil (EO20) 2.0 Squalane 0.5 1-Isostearoyl-3-myristoyl glycerol (DGMI) 1.5 86% Glycerol 2.0 Propylene Glycol 1.0 Sericite 3.0 Ethanol 5.0 Preservative Appropriate amount Water balance

Example 5 A keratin plug removing agent having the following composition was produced. Polymethacryloyloxytrimethylammonium chloride (QDM) (Mw 200,000) 15.0 (wt%) Polymethacrylamidopropyltrimethylammonium chloride (MAPTAC) (Mw 300,000) 15.0 Polyoxyethylene hydrogenated castor oil (EO40) 1.5 Squalane 0.5 2- Ethylhexanoic acid triglyceride 2.0 Sorbitol 3.0 Kaolin 7.0 Titanium oxide 2.0 Ethanol 5.0 Preservatives Water balance

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[Procedure amendment]

[Submission date] June 2, 1992

[Procedure Amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0016

[Correction method] Change

[Correction content]

The molecular weight of these polymer compounds is
Those in the range of 10,000 to 3,000,000 are preferable, and particularly 100,000 to
One million is preferable. If the molecular weight is less than 10,000, insufficient strength of the film-forming films, weakens the tension to the skin, is easily broken at the time of peeling, whereas 300
Manufacturing more than 10,000 is difficult.

[Procedure Amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0018

[Correction method] Change

[Correction content]

The above-mentioned synthetic polymer compound is used by being dissolved in a solvent, which is volatile.
The polymer compound is not particularly limited as long as it can stably dissolve the polymer compound and is safe for the skin. For example, water, ethanol,
Isopropyl alcohol (IPA) etc. alone or in two kinds
The above is used in combination . The blending amount of this solvent may be appropriately determined depending on the polymer compound, the optional component and the dosage form, but is generally 30 to 99.99% by weight, particularly 60 to 9%.
5% by weight is preferred.

[Procedure 3]

[Document name to be amended] Statement

[Name of item to be corrected] 0019

[Correction method] Change

[Correction content]

The keratin plug removing agent of the present invention contains, in addition to the above components,
Ingredients commonly used in cosmetics, such as ethylene glycol, diethylene glycol, triethylene glycol, higher polyethylene glycols, propylene glycol, dipropylene glycol, higher polypropylene glycols, 1,3-butylene glycol, 1,4 -Butylene glycols such as butylene glycol, glycerin, diglycerin, further polyglycerins, sugar alcohols such as sorbitol, mannitol, xylitol, maltitol, ethylene oxide (hereinafter abbreviated as EO) of glycerins, propylene oxide ( Hereinafter, abbreviated as PO) adducts, EO of sugar alcohols, PO adducts, monosaccharides such as galactose, glucose and fructose, and polysaccharides such as EO, PO adducts, maltose and lactose. Polyhydric alcohols such as EO and PO adducts; hydrocarbons such as liquid paraffin, squalane, vaseline and solid paraffin, natural oils such as olive oil, jojoba oil, evening primrose oil, coconut oil and beef tallow, isopropyl myristate, cetyl isoocta Noate, ester oils such as neopentyl glycol dicaprate, silicone oils such as methyl silicone and methyl phenyl silicone, oily components such as higher fatty acids such as isostearic acid and oleic acid; POE alkyl ether, POB branched alkyl ether, POE sorbitan ester , POB glycerin fatty acid ester, POE hydrogenated castor oil, sorbitan ester, glycerin fatty acid ester, polyglycerin fatty acid ester and other surfactants; vitamins, anti-inflammatory agents, bactericides, activators, UV absorbers and other agents; Mori b Na <br/> site, saponite, water-swellable clay minerals, such as hectorite; carrageenan, xanthan gum, sodium alginate, pullulan, methylcellulose, carboxymethylcellulose, hydroxyethylcellulose, polysaccharides such as hydroxypropylcellulose, carboxyvinyl polymers, Other polymers such as polyvinylpyrrolidone, polyvinyl alcohol, and other synthetic polymers; extenders such as titanium oxide, kaolin, mica, sericite, zinc white, talc, and polymer powders such as polymethylmethacrylic acid and nylon powder. The pigment and the like can be appropriately blended within a range that does not impair the effects of the present invention. Of these ingredients,
When an oily component is blended, the peel strength of the film formed during drying can be adjusted, and the film can be peeled satisfactorily without irritating the skin. Further, it is preferable to add the polyhydric alcohol in an amount of 0.01 to 50% by weight based on the total composition.

[Procedure correction 4]

[Document name to be amended] Statement

[Name of item to be corrected] 0020

[Correction method] Change

[Correction content]

The dosage form of the keratotic plug removing agent of the present invention is a pack agent.
Other, cotton, staple fiber fabric, Tetron, coating the woven fabric or plastic sheet such as nylon, may be used as cataplasm. Well
To remove keratin plugs using the keratin plug removing agent of the present invention,
For example, apply the above-mentioned pack or poultice to the skin (for example, nose, forehead,
Apply or paste on the part where the square plug exists, such as the jaw, and dry.
After that, it may be peeled from the skin.

Claims (4)

[Claims] 1. A keratotic plug removing agent comprising a polymer compound having a salt-forming group. 2. An agent for removing keratotic plugs, which comprises a synthetic polymer compound having a salt-forming group. 3. The salt-forming group is one or more groups selected from a carboxyl group, a sulfonic acid residue, a sulfuric acid residue, a phosphoric acid residue, a nitric acid residue, an amino group and an ammonium group. Item 2. A plug removal agent according to item 1. 4. A method of removing a keratin plug by applying a composition containing a polymer compound having a salt-forming group to the skin, drying the composition, and peeling the composition from the skin.