JPH0571599B2 - - Google Patents

Info

Publication number
JPH0571599B2
JPH0571599B2 JP61246238A JP24623886A JPH0571599B2 JP H0571599 B2 JPH0571599 B2 JP H0571599B2 JP 61246238 A JP61246238 A JP 61246238A JP 24623886 A JP24623886 A JP 24623886A JP H0571599 B2 JPH0571599 B2 JP H0571599B2
Authority
JP
Japan
Prior art keywords
culture
methanol
strain
antitumor
streptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61246238A
Other languages
English (en)
Japanese (ja)
Other versions
JPS63101336A (ja
Inventor
Hirofumi Nakano
Mitsunobu Hara
Kozo Asano
Mayumi Koda
Makoto Morimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP61246238A priority Critical patent/JPS63101336A/ja
Priority to EP87115147A priority patent/EP0264138B1/en
Priority to DE8787115147T priority patent/DE3774994D1/de
Publication of JPS63101336A publication Critical patent/JPS63101336A/ja
Publication of JPH0571599B2 publication Critical patent/JPH0571599B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/165—Heterorings having nitrogen atoms as the only ring heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP61246238A 1986-10-16 1986-10-16 新規物質ｄｃ―１０２ Granted JPS63101336A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP61246238A JPS63101336A (ja) 1986-10-16 1986-10-16 新規物質ｄｃ―１０２
EP87115147A EP0264138B1 (en) 1986-10-16 1987-10-16 Novel compound dc-102 and process for production thereof
DE8787115147T DE3774994D1 (de) 1986-10-16 1987-10-16 Verbindung dc-102 und verfahren zu ihrer herstellung.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61246238A JPS63101336A (ja) 1986-10-16 1986-10-16 新規物質ｄｃ―１０２

Publications (2)

Publication Number Publication Date
JPS63101336A JPS63101336A (ja) 1988-05-06
JPH0571599B2 true JPH0571599B2 (en, 2012) 1993-10-07

Family

ID=17145563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61246238A Granted JPS63101336A (ja) 1986-10-16 1986-10-16 新規物質ｄｃ―１０２

Country Status (3)

Country Link
EP (1) EP0264138B1 (en, 2012)
JP (1) JPS63101336A (en, 2012)
DE (1) DE3774994D1 (en, 2012)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08128465A (ja) * 1994-11-01 1996-05-21 Nsk Warner Kk ワンウェイクラッチの潤滑機構

Also Published As

Publication number Publication date
EP0264138B1 (en) 1991-12-04
JPS63101336A (ja) 1988-05-06
EP0264138A3 (en) 1988-09-14
EP0264138A2 (en) 1988-04-20
DE3774994D1 (de) 1992-01-16

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