JPH0555508B2 - - Google Patents

Info

Publication number
JPH0555508B2
JPH0555508B2 JP8471047A JP7104784A JPH0555508B2 JP H0555508 B2 JPH0555508 B2 JP H0555508B2 JP 8471047 A JP8471047 A JP 8471047A JP 7104784 A JP7104784 A JP 7104784A JP H0555508 B2 JPH0555508 B2 JP H0555508B2
Authority
JP
Japan
Prior art keywords
group
formula
alk
carbon atoms
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP8471047A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59205382A (ja
Inventor
Mohanraru Baizu Doratorai
Uiriamu Doiru Terensu
Chan Yuurin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JPS59205382A publication Critical patent/JPS59205382A/ja
Publication of JPH0555508B2 publication Critical patent/JPH0555508B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP59071047A 1983-04-11 1984-04-11 アミノ２硫化物 Granted JPS59205382A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48401683A 1983-04-11 1983-04-11
US581291 1984-02-24
US484016 1990-02-23

Publications (2)

Publication Number Publication Date
JPS59205382A JPS59205382A (ja) 1984-11-20
JPH0555508B2 true JPH0555508B2 (enrdf_load_stackoverflow) 1993-08-17

Family

ID=23922390

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59071047A Granted JPS59205382A (ja) 1983-04-11 1984-04-11 アミノ２硫化物

Country Status (4)

Country Link
JP (1) JPS59205382A (enrdf_load_stackoverflow)
KR (1) KR840008362A (enrdf_load_stackoverflow)
BE (1) BE899380A (enrdf_load_stackoverflow)
ZA (1) ZA842596B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
JPH066591B2 (ja) * 1985-04-10 1994-01-26 協和醗酵工業株式会社 マイトマイシン誘導体及び抗腫瘍剤
JPH0745503B1 (enrdf_load_stackoverflow) * 1986-08-29 1995-05-17 Kyowa Hakko Kogyo Kk
DE3750846T2 (de) * 1986-08-29 1995-05-11 Kyowa Hakko Kogyo Kk Mitomycin-derivate.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104386A (ja) * 1982-12-07 1984-06-16 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS59175493A (ja) * 1983-03-25 1984-10-04 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体

Also Published As

Publication number Publication date
KR840008362A (ko) 1984-12-14
BE899380A (fr) 1984-10-10
ZA842596B (en) 1984-11-28
JPS59205382A (ja) 1984-11-20

Similar Documents

Publication Publication Date Title
EP0116208B1 (en) Mitomycin analogues
US4866180A (en) Amino disulfide thiol exchange products
US11926641B2 (en) Phosphonamidate butyrophilin ligands
WO2020210970A1 (en) Imidazotriazine derivatives as cd73 inhibitors
KR890001488B1 (ko) 미토마이신 c 유도체의 제조방법
NZ204352A (en) Mitomycin analogs carrying one or more guanidino substituents in the 7- and/or 10-positions
JPH0555508B2 (enrdf_load_stackoverflow)
FI81099B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva mitomycinanaloger.
US4814445A (en) Process for preparing mitomycin analogs
CA1291293C (en) Substituted 7-oxomitosanes
EP0390181B1 (en) Perylenequinone (UCN-1028D) derivatives
US4927943A (en) Substituted 7-oxomitosanes
US4771068A (en) Mitomycin derivatives having anti-tumor and antibacterial utility
AU2006243407A1 (en) Antitumoral tetrahydro-pyrimidines
US5097036A (en) Substituted 7-oxomitosanes
US5099016A (en) Substituted 7-oxomitosanes
WO2012050465A1 (en) Novel esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin - thioredoxin reductase system
Visnevska et al. Evaluation of (E)-2-chlorovinylsulfones as novel class of cytotoxic agents and highly (E)-stereoselective addition of N-, S-and Senucleophiles to (E)-2-chlorovinylsulfones under phase transfer catalysis conditions
Kochikyan et al. Synthesis and biological activity of 3-methyl-3-(3′-aminothiazol-4-yl)-8-alkoxymethyl-2, 7-dioxaspiro [4, 4] nonane-1, 6-diones.
IE58936B1 (en) Preparation of pyrroloindole derivatives