JPH0554979B2 - - Google Patents
Info
- Publication number
- JPH0554979B2 JPH0554979B2 JP8778487A JP7848787A JPH0554979B2 JP H0554979 B2 JPH0554979 B2 JP H0554979B2 JP 8778487 A JP8778487 A JP 8778487A JP 7848787 A JP7848787 A JP 7848787A JP H0554979 B2 JPH0554979 B2 JP H0554979B2
- Authority
- JP
- Japan
- Prior art keywords
- sensor
- blood
- infusion
- volume
- infusion pump
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000001802 infusion Methods 0.000 claims description 85
- 210000004369 blood Anatomy 0.000 claims description 82
- 239000008280 blood Substances 0.000 claims description 82
- 239000000126 substance Substances 0.000 claims description 62
- 239000000306 component Substances 0.000 claims description 59
- 239000012503 blood component Substances 0.000 claims description 33
- 238000012806 monitoring device Methods 0.000 claims description 31
- 230000002441 reversible effect Effects 0.000 claims description 27
- 238000005259 measurement Methods 0.000 claims description 25
- 210000004204 blood vessel Anatomy 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 22
- 239000000243 solution Substances 0.000 claims description 22
- 238000005086 pumping Methods 0.000 claims description 16
- 238000012545 processing Methods 0.000 claims description 15
- 238000001514 detection method Methods 0.000 claims description 14
- 239000003978 infusion fluid Substances 0.000 claims description 11
- 238000012937 correction Methods 0.000 claims description 10
- 238000002474 experimental method Methods 0.000 claims description 8
- 238000010992 reflux Methods 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 40
- 230000004044 response Effects 0.000 description 30
- 230000006870 function Effects 0.000 description 20
- BPKIGYQJPYCAOW-FFJTTWKXSA-I calcium;potassium;disodium;(2s)-2-hydroxypropanoate;dichloride;dihydroxide;hydrate Chemical compound O.[OH-].[OH-].[Na+].[Na+].[Cl-].[Cl-].[K+].[Ca+2].C[C@H](O)C([O-])=O BPKIGYQJPYCAOW-FFJTTWKXSA-I 0.000 description 13
- 239000007789 gas Substances 0.000 description 10
- 239000011734 sodium Substances 0.000 description 7
- 238000001179 sorption measurement Methods 0.000 description 7
- 239000011575 calcium Substances 0.000 description 6
- 230000007423 decrease Effects 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 229960002897 heparin Drugs 0.000 description 4
- 229920000669 heparin Polymers 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- 238000002955 isolation Methods 0.000 description 4
- 241000282472 Canis lupus familiaris Species 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- -1 lactate ion Chemical class 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 102000004506 Blood Proteins Human genes 0.000 description 2
- 108010017384 Blood Proteins Proteins 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 102000008946 Fibrinogen Human genes 0.000 description 2
- 108010049003 Fibrinogen Proteins 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229940012952 fibrinogen Drugs 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000012086 standard solution Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- VOZDNCFKGOLECZ-BTVCFUMJSA-N 2-hydroxypropanoic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O VOZDNCFKGOLECZ-BTVCFUMJSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 208000028399 Critical Illness Diseases 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229910052581 Si3N4 Inorganic materials 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229960004676 antithrombotic agent Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 239000012482 calibration solution Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005669 field effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical group [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 238000012886 linear function Methods 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000036387 respiratory rate Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229940045136 urea Drugs 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
- 
        - G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4925—Blood measuring blood gas content, e.g. O2, CO2, HCO3
 
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- External Artificial Organs (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| JP7888186 | 1986-04-05 | ||
| JP61-78881 | 1986-04-05 | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| JPS6340532A JPS6340532A (ja) | 1988-02-20 | 
| JPH0554979B2 true JPH0554979B2 (OSRAM) | 1993-08-13 | 
Family
ID=13674155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| JP62078487A Granted JPS6340532A (ja) | 1986-04-05 | 1987-03-30 | 血液成分の監視装置 | 
Country Status (4)
| Country | Link | 
|---|---|
| US (1) | US4736748A (OSRAM) | 
| EP (1) | EP0242644B1 (OSRAM) | 
| JP (1) | JPS6340532A (OSRAM) | 
| DE (1) | DE3780061T2 (OSRAM) | 
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JP2008194488A (ja) * | 1999-11-30 | 2008-08-28 | Nippon Koden Corp | ヘモグロビン濃度測定装置 | 
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JPS63160635A (ja) * | 1986-12-23 | 1988-07-04 | 三菱レイヨン株式会社 | 生体成分測定用具 | 
| US5048525A (en) * | 1987-01-30 | 1991-09-17 | Minnesota Mining And Manufacturing Company | Blood parameter measurement system with compliant element | 
| US5462052A (en) * | 1987-01-30 | 1995-10-31 | Minnesota Mining And Manufacturing Co. | Apparatus and method for use in measuring a compositional parameter of blood | 
| US4934369A (en) * | 1987-01-30 | 1990-06-19 | Minnesota Mining And Manufacturing Company | Intravascular blood parameter measurement system | 
| US4830013A (en) * | 1987-01-30 | 1989-05-16 | Minnesota Mining And Manufacturing Co. | Intravascular blood parameter measurement system | 
| US4989606A (en) * | 1987-01-30 | 1991-02-05 | Minnesota Mining And Manufactoring Company | Intravascular blood gas sensing system | 
| US4951669A (en) * | 1987-01-30 | 1990-08-28 | Minnesota Mining And Manufacturing Company | Blood parameter measurement system | 
| US4976682A (en) * | 1987-11-23 | 1990-12-11 | Lane Perry L | Methods and apparatus for autologous blood recovery | 
| CA2034285A1 (en) * | 1990-02-09 | 1991-08-10 | Masao Yafuso | Method and system for monitoring of blood constituents in vivo | 
| US5175016A (en) * | 1990-03-20 | 1992-12-29 | Minnesota Mining And Manufacturing Company | Method for making gas sensing element | 
| US5639382A (en) * | 1991-12-23 | 1997-06-17 | Baxter International Inc. | Systems and methods for deriving recommended storage parameters for collected blood components | 
| US5730883A (en) | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter | 
| US5681273A (en) * | 1991-12-23 | 1997-10-28 | Baxter International Inc. | Systems and methods for predicting blood processing parameters | 
| US6007725A (en) | 1991-12-23 | 1999-12-28 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort | 
| US5676841A (en) * | 1991-12-23 | 1997-10-14 | Baxter International Inc. | Blood processing systems and methods which monitor citrate return to the donor | 
| US5833866A (en) * | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing | 
| US5804079A (en) | 1991-12-23 | 1998-09-08 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes | 
| US5817042A (en) * | 1992-03-04 | 1998-10-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems | 
| US5421812A (en) * | 1992-03-04 | 1995-06-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in tubing system | 
| US5676645A (en) * | 1992-03-04 | 1997-10-14 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems | 
| US5335658A (en) * | 1992-06-29 | 1994-08-09 | Minnesota Mining And Manufacturing Company | Intravascular blood parameter sensing system | 
| FR2693110B1 (fr) * | 1992-07-06 | 1994-08-19 | Hospal Ind | Procédé de vérification du fonctionnement de capteurs situés sur un circuit de liquide de dialyse et dispositif en faisant application. | 
| US5330634A (en) * | 1992-08-28 | 1994-07-19 | Via Medical Corporation | Calibration solutions useful for analyses of biological fluids and methods employing same | 
| US5551425A (en) * | 1993-05-13 | 1996-09-03 | Synectics Medical, Inc. | Potential difference and perfusion pressure catheter | 
| US5405511A (en) * | 1993-06-08 | 1995-04-11 | Boehringer Mannheim Corporation | Biosensing meter with ambient temperature estimation method and system | 
| US5477468A (en) * | 1994-01-14 | 1995-12-19 | Project Cd | Concentration analyzer | 
| US5759413A (en) * | 1995-06-07 | 1998-06-02 | Baxter International Inc. | Systems and method for estimating platelet counts using a spleen mobilization function | 
| US5641006A (en) * | 1995-07-13 | 1997-06-24 | Chiron Diagnostics Corporation | Liquid supply apparatus and method of operation | 
| US5735387A (en) * | 1995-07-14 | 1998-04-07 | Chiron Diagnostics Corporation | Specimen rack handling system | 
| US5720377A (en) * | 1995-07-14 | 1998-02-24 | Chiron Diagnostics Corporation | Magnetic conveyor system | 
| US5984892A (en) * | 1996-09-16 | 1999-11-16 | Minnesota Mining And Manufacturing Company | Blood aspirator | 
| WO1998032013A1 (en) * | 1997-01-17 | 1998-07-23 | Via Medical Corporation | Method for calibrating sensors used in diagnostic testing | 
| US8128595B2 (en) * | 1998-04-21 | 2012-03-06 | Zoll Circulation, Inc. | Method for a central venous line catheter having a temperature control system | 
| US6146411A (en) | 1998-12-24 | 2000-11-14 | Alsius Corporation | Cooling system for indwelling heat exchange catheter | 
| EP1130393A3 (en) * | 2000-02-03 | 2001-11-28 | Nihon Kohden Corporation | Gas sensor and gas sensor system | 
| DE60336834D1 (de) | 2002-10-09 | 2011-06-01 | Abbott Diabetes Care Inc | Kraftstoffzufuhrvorrichtung, system und verfahren | 
| US7993108B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump | 
| US7399401B2 (en) * | 2002-10-09 | 2008-07-15 | Abbott Diabetes Care, Inc. | Methods for use in assessing a flow condition of a fluid | 
| US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration | 
| US7278984B2 (en) | 2002-12-31 | 2007-10-09 | Alsius Corporation | System and method for controlling rate of heat exchange with patient | 
| US7383071B1 (en) * | 2003-04-25 | 2008-06-03 | United States Of America As Represented By The Secretary Of The Navy | Microsensor system and method for measuring data | 
| US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems | 
| US7986986B2 (en) | 2003-08-01 | 2011-07-26 | Dexcom, Inc. | System and methods for processing analyte sensor data | 
| US8626257B2 (en) | 2003-08-01 | 2014-01-07 | Dexcom, Inc. | Analyte sensor | 
| US20080119703A1 (en) | 2006-10-04 | 2008-05-22 | Mark Brister | Analyte sensor | 
| US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data | 
| US8886273B2 (en) * | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor | 
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor | 
| US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data | 
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor | 
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration | 
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor | 
| US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor | 
| US20080197024A1 (en) * | 2003-12-05 | 2008-08-21 | Dexcom, Inc. | Analyte sensor | 
| US8425417B2 (en) * | 2003-12-05 | 2013-04-23 | Dexcom, Inc. | Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device | 
| US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor | 
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor | 
| US8425416B2 (en) * | 2006-10-04 | 2013-04-23 | Dexcom, Inc. | Analyte sensor | 
| US20080200788A1 (en) * | 2006-10-04 | 2008-08-21 | Dexcorn, Inc. | Analyte sensor | 
| US8364230B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor | 
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor | 
| WO2009048462A1 (en) | 2007-10-09 | 2009-04-16 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor | 
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor | 
| US7654956B2 (en) | 2004-07-13 | 2010-02-02 | Dexcom, Inc. | Transcutaneous analyte sensor | 
| US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor | 
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor | 
| US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness | 
| US7468033B2 (en) * | 2004-09-08 | 2008-12-23 | Medtronic Minimed, Inc. | Blood contacting sensor | 
| US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor | 
| JP2008535548A (ja) * | 2005-03-21 | 2008-09-04 | アボット ダイアビーティーズ ケア インコーポレイテッド | 統合医薬注入/検体モニタリングシステムを提供するための方法及びシステム | 
| US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system | 
| US7620437B2 (en) | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems | 
| US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems | 
| US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device | 
| US8478377B2 (en) * | 2006-10-04 | 2013-07-02 | Dexcom, Inc. | Analyte sensor | 
| US8449464B2 (en) * | 2006-10-04 | 2013-05-28 | Dexcom, Inc. | Analyte sensor | 
| US8275438B2 (en) * | 2006-10-04 | 2012-09-25 | Dexcom, Inc. | Analyte sensor | 
| US8298142B2 (en) * | 2006-10-04 | 2012-10-30 | Dexcom, Inc. | Analyte sensor | 
| US8447376B2 (en) | 2006-10-04 | 2013-05-21 | Dexcom, Inc. | Analyte sensor | 
| US8562528B2 (en) * | 2006-10-04 | 2013-10-22 | Dexcom, Inc. | Analyte sensor | 
| US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods | 
| WO2008118919A1 (en) | 2007-03-26 | 2008-10-02 | Dexcom, Inc. | Analyte sensor | 
| US20080249385A1 (en) * | 2007-04-04 | 2008-10-09 | Luong Ngoc Phan | Isolated intravenous analyte monitoring system | 
| WO2008154312A1 (en) | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor | 
| JP5034720B2 (ja) * | 2007-07-04 | 2012-09-26 | パナソニック株式会社 | 血糖値測定システム | 
| US20090240121A1 (en) * | 2008-03-21 | 2009-09-24 | Nova Biomedical Corporation | Intravascular sensor and insertion set combination | 
| US8396528B2 (en) * | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor | 
| US20100331644A1 (en) * | 2008-11-07 | 2010-12-30 | Dexcom, Inc. | Housing for an intravascular sensor | 
| US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing | 
| WO2010129375A1 (en) | 2009-04-28 | 2010-11-11 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis | 
| EP2448486B1 (en) * | 2009-07-02 | 2021-08-25 | Dexcom, Inc. | Analyte sensors and methods of manufacturing same | 
| US9351677B2 (en) | 2009-07-02 | 2016-05-31 | Dexcom, Inc. | Analyte sensor with increased reference capacity | 
| US8798934B2 (en) | 2009-07-23 | 2014-08-05 | Abbott Diabetes Care Inc. | Real time management of data relating to physiological control of glucose levels | 
| EP2697650B1 (en) | 2011-04-15 | 2020-09-30 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection | 
| US9239386B2 (en) | 2011-10-05 | 2016-01-19 | Infineon Technologies Ag | Sonic sensors and packages | 
| JP6281735B2 (ja) * | 2013-03-19 | 2018-02-21 | トーアエイヨー株式会社 | 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法 | 
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors | 
| US20190120785A1 (en) | 2017-10-24 | 2019-04-25 | Dexcom, Inc. | Pre-connected analyte sensors | 
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US4109505A (en) * | 1974-07-22 | 1978-08-29 | Primary Children's Hospital | Automated blood analysis system | 
| US4119406A (en) * | 1976-05-06 | 1978-10-10 | Miles Laboratories, Inc. | Calibration apparatus | 
| DE2911601C2 (de) * | 1979-03-24 | 1982-05-13 | Hellige Gmbh, 7800 Freiburg | Meßwertaufnehmer für physiologische Meßgrößen mit einer Einrichtung zur elektrischen Beheizung | 
| US4283262A (en) * | 1980-07-01 | 1981-08-11 | Instrumentation Laboratory Inc. | Analysis system | 
| US4512348A (en) * | 1981-04-24 | 1985-04-23 | Kabushiki Kaisha Kyoto Daiichi Kagaku | Device for automatically and continuously measuring the constituent parts of blood | 
| US4516580A (en) * | 1981-12-28 | 1985-05-14 | Polanyi Michael L | Continuous blood gas monitoring | 
| JPS58198351A (ja) * | 1982-05-15 | 1983-11-18 | 株式会社京都第一科学 | 希釈される体液中の特定成分を連続的に測定する装置 | 
- 
        1987
        - 1987-03-30 JP JP62078487A patent/JPS6340532A/ja active Granted
- 1987-03-31 DE DE8787104769T patent/DE3780061T2/de not_active Expired - Fee Related
- 1987-03-31 EP EP87104769A patent/EP0242644B1/en not_active Expired
- 1987-04-03 US US07/034,026 patent/US4736748A/en not_active Expired - Fee Related
 
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| JP2008194488A (ja) * | 1999-11-30 | 2008-08-28 | Nippon Koden Corp | ヘモグロビン濃度測定装置 | 
Also Published As
| Publication number | Publication date | 
|---|---|
| EP0242644A2 (en) | 1987-10-28 | 
| EP0242644A3 (en) | 1989-04-05 | 
| JPS6340532A (ja) | 1988-02-20 | 
| US4736748A (en) | 1988-04-12 | 
| DE3780061T2 (de) | 1993-01-28 | 
| DE3780061D1 (de) | 1992-08-06 | 
| EP0242644B1 (en) | 1992-07-01 | 
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