JPH05507064A - γ―ブチロラクトールエーテル誘導体 - Google Patents

γ―ブチロラクトールエーテル誘導体

Info

Publication number
JPH05507064A
JPH05507064A JP91507515A JP50751591A JPH05507064A JP H05507064 A JPH05507064 A JP H05507064A JP 91507515 A JP91507515 A JP 91507515A JP 50751591 A JP50751591 A JP 50751591A JP H05507064 A JPH05507064 A JP H05507064A
Authority
JP
Japan
Prior art keywords
group
pyridyl
general formula
ether
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP91507515A
Other languages
English (en)
Japanese (ja)
Inventor
ウィタッカー　マーク
ディヴィッドソン　アレン　ホーンズビー
スパヴォールド　ゾーイ　マリー
ボールズ　スティーヴン　アーサー
Original Assignee
ブリティッシュ　バイオ―テクノロジー　リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ブリティッシュ　バイオ―テクノロジー　リミテッド filed Critical ブリティッシュ　バイオ―テクノロジー　リミテッド
Publication of JPH05507064A publication Critical patent/JPH05507064A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
JP91507515A 1990-04-27 1991-04-16 γ―ブチロラクトールエーテル誘導体 Pending JPH05507064A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9009469.9 1990-04-27
GB909009469A GB9009469D0 (en) 1990-04-27 1990-04-27 Compounds
PCT/GB1991/000596 WO1991017157A1 (en) 1990-04-27 1991-04-16 Gamma-butyrolactol ether derivatives

Publications (1)

Publication Number Publication Date
JPH05507064A true JPH05507064A (ja) 1993-10-14

Family

ID=10675085

Family Applications (1)

Application Number Title Priority Date Filing Date
JP91507515A Pending JPH05507064A (ja) 1990-04-27 1991-04-16 γ―ブチロラクトールエーテル誘導体

Country Status (13)

Country Link
US (1) US5428168A (OSRAM)
EP (1) EP0527817A1 (OSRAM)
JP (1) JPH05507064A (OSRAM)
AU (1) AU645082B2 (OSRAM)
CA (1) CA2080346A1 (OSRAM)
FI (1) FI924855A7 (OSRAM)
GB (1) GB9009469D0 (OSRAM)
IE (1) IE911328A1 (OSRAM)
NZ (1) NZ237779A (OSRAM)
PT (1) PT97503A (OSRAM)
TW (1) TW221999B (OSRAM)
WO (1) WO1991017157A1 (OSRAM)
ZA (1) ZA912715B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007277255A (ja) * 2000-10-19 2007-10-25 Pfizer Japan Inc 抗炎症剤及び鎮痛剤としてのアリール又はヘテロアリール縮合イミダゾール化合物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114337D0 (en) * 1991-07-03 1991-08-21 British Bio Technology Compounds
GB9122308D0 (en) * 1991-10-21 1991-12-04 British Bio Technology Compounds
GB9202792D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
CA2140034A1 (en) 1992-07-13 1994-01-20 Xiong Cai 2,5-diaryl tetrahydro-thiophenes, -furans and analogs for the treatment of inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US6201016B1 (en) 1994-06-27 2001-03-13 Cytomed Incorporated Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
PL317873A1 (en) * 1994-06-27 1997-04-28 Cytomed Inc Compounds for and method of treating cardiovascular, inflammatory and immunological disorders
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US6124463A (en) * 1998-07-02 2000-09-26 Dupont Pharmaceuticals Benzimidazoles as corticotropin release factor antagonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539332A (en) * 1983-11-14 1985-09-03 Merck & Co., Inc. 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
NZ215866A (en) * 1985-04-22 1989-11-28 Merck & Co Inc 2,5-di(aryl/heterocyclyl) tetrahydro-furans and pharmaceutical compositions
EP0226641B1 (en) * 1985-05-25 1989-10-18 Yoshitomi Pharmaceutical Industries, Ltd. Oxodiazine compounds
JP2556849B2 (ja) * 1986-02-13 1996-11-27 三共株式会社 グリセリン誘導体
GB8701727D0 (en) * 1987-01-27 1987-03-04 Scras Tetrahydrofuran derivatives
US4820718A (en) * 1987-09-17 1989-04-11 Sandoz Pharm. Corp. N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts and use thereof in PAF inhibition
GB8814340D0 (en) * 1988-06-16 1988-07-20 Ici Plc Process
ES2010568A6 (es) * 1988-08-04 1989-11-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 2,5-disustituidos de tetrahidrofurano.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007277255A (ja) * 2000-10-19 2007-10-25 Pfizer Japan Inc 抗炎症剤及び鎮痛剤としてのアリール又はヘテロアリール縮合イミダゾール化合物

Also Published As

Publication number Publication date
PT97503A (pt) 1992-01-31
FI924855A0 (fi) 1992-10-26
GB9009469D0 (en) 1990-06-20
NZ237779A (en) 1992-11-25
CA2080346A1 (en) 1991-10-28
IE911328A1 (en) 1991-11-06
WO1991017157A1 (en) 1991-11-14
AU7658591A (en) 1991-11-27
TW221999B (OSRAM) 1994-04-01
AU645082B2 (en) 1994-01-06
EP0527817A1 (en) 1993-02-24
US5428168A (en) 1995-06-27
FI924855A7 (fi) 1992-10-26
ZA912715B (en) 1992-03-25

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