JPH0542205A - Method for supplying chemical to hemodialyzer - Google Patents

Abstract

PURPOSE:To make a hemodialyzer smaller, to reduce costs, and to save chemicals by providing a chemical supply mechanism which has a simple configuration and efficiently disinfects and washes a dialysis liquid circuit in the hemodialyzer. CONSTITUTION:A line 19 which supplies rich chemicals to a dialysis liquid supply line or a drainage line for a dialyzer provided and rich chemicals are introduced by a feed water pump 11 into a dialysis circuit before the chemicals are circulated with a dialysis circuit closed so that the chemicals are diluted to a target concentration and the circuit is efficiently washed and disinfected.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a chemical liquid supply device for supplying a chemical liquid for disinfection and cleaning in a hemodialysis device into the dialysis device, adjusting its concentration, and circulating the liquid inside the dialysis device.

[0002]

2. Description of the Related Art Hemodialysis treatment aims to remove unwanted substances in blood through a dialysate. Therefore, in a dialysis machine that supplies a dialysate, unlike a disposable dialyzer and a blood tube, cleaning and disinfection are indispensable every time one treatment is completed. Therefore, conventionally, hot water has been poured into the dialysis machine, or cleaning and disinfection using a hypochlorous acid-based disinfectant or the like has been performed. Further, in recent dialysis treatment, a bicarbonate-based solution is often used as a dialysate, and in this case, an acid solution such as acetic acid is used because carbonate adheres to the dialysate channel in the dialyzer. Then, the removal is done.

Conventionally, the chemical solution for cleaning or disinfecting is prepared by mixing a concentrated solution and diluting water at a predetermined ratio by a dedicated metering pump provided in a dialysis machine to prepare a solution having a predetermined concentration. Alternatively, a method has been adopted in which a solution prepared in advance to a predetermined concentration is introduced into the dialysis device. Therefore, when cleaning and disinfecting with a dedicated metering pump in the dialysis machine, it is necessary to add not only the metering pump but also various parts such as a mixing tank, which is a factor that hinders downsizing of the apparatus and cost reduction. There is. Further, when introducing a drug solution prepared to a predetermined concentration into the dialysis device, a dedicated mixing device is required separately, so a complicated system including piping to the dialysis device and complicated operation become a problem. There is.

Further, in these methods, a large amount of chemical liquid is required in order to constantly supply the concentration-adjusted chemical liquid, pass it through the dialysate circuit in the dialyzer, and discharge it as it is to the outside. However, for the purpose of improving such inconvenience, a closed circuit is formed by the dialysate supply line and the drain line of the dialysate circuit, the internal liquid is circulated by the feed pump, and the drain metering pump is used. A method has been proposed in which the liquid concentration is adjusted by draining the internal liquid from the above-mentioned closed circuit and causing a concentrated liquid chemical to flow from a liquid intake port connected in the closed circuit (Japanese Patent Publication No. 2-60345).

[0005]

In the above-mentioned method, no special metering pump or mixing tank is required to adjust the concentration of the liquid chemical, and the liquid is circulated in the closed circuit so that the liquid chemical can be saved. It is more effective than the conventional method. However, since the diluted water in the closed circuit is circulated and discharged, and the concentrated chemical liquid is introduced into the closed circuit by the discharged amount, the chemical liquid is constantly discharged little by little. It will take an extra time to reach the concentration. Further, there is a problem that the adjustment to a predetermined density is ambiguous unless a density sensor or the like is provided.

In view of the above points, it is an object of the present invention to provide a method and apparatus for supplying a chemical solution which takes a short time to reach a predetermined concentration and which wastes less chemical solution.

[0007]

In order to solve the above problems, the present invention is provided with a liquid supply pump, a liquid supply line for supplying dialysate to a dialyzer, and a drainage pump. A drainage line for discharging dialysis waste liquid from the drainage line, a drainage line bypassing the drainage pump and having its flow rate controlled by a drainage pump, and a chemical liquid supply line connected to the liquid supply line or the drainage line. And a method of supplying a drug solution to a hemodialysis device comprising an external connection end of the liquid supply line and a bypass line connecting the external connection end of the drainage line, wherein the external connection end of the liquid supply line is closed, With the external connection end of the drainage line open, the dewatering pump is operated to introduce a predetermined concentrated drug solution from the drug solution supply line into the solution supply line or the drainage line, and then the bypass line. The concentrated chemical introduced is opened by opening the concentrated chemical to circulate through the bypass line to the liquid supply line, the drain line and the water removal line to mix with the remaining liquid to dilute the concentrated chemical to a predetermined concentration. It is characterized by that.

[0008]

[Operation] With the external connection end of the liquid supply line closed and the external connection end of the drainage line open, the dewatering pump is operated to introduce a predetermined concentrated chemical liquid from the chemical liquid supply line to the liquid supply line or the drainage line. .. At this time, since the bypass line is closed, the liquid supply line and the liquid drain line are not closed circuits,
A quantity of concentrated drug solution calculated from the volume of the dialysate circuit and the target concentration of the drug solution is injected into the dialysate circuit. Next, a bypass line is connected to connect the external connection end of the liquid supply line and the external connection end of the drainage line, and form a closed circuit with the liquid supply line, the drainage line, and the water removal line, and circulate and close. The concentrated drug solution can be diluted to a predetermined concentration by mixing with the liquid remaining in the circuit.

[0009]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The chemical liquid supply device of the present invention will be described in detail below with reference to the drawings. FIG. 1 shows a dialysate circuit in a hemodialysis apparatus for explaining an embodiment of the present invention. In the figure, 7 is a dialyzer, 1 and 6 are liquid supply lines, and 8 and 9.
Is a drain line, 19 is a chemical supply line, 12 is a drainage line, 11 is a drainage pump, 13 is a bypass coupler for connecting the dialyser side end of the feed line and the drainage line, 23
Is a bypass line connecting the external connection end of the liquid supply line and the external connection end of the liquid discharge line.

Reference numeral 5 denotes a double pump, which comprises a supply pump for supplying dialysate and a drainage pump for discharging waste dialysate as one pump. Further, the liquid feed pump 10 is used as a pressurizing pump in order to make the operating conditions of the double pump 5 constant and improve the accuracy. The operation of the dialysis machine in normal dialysis treatment is as follows. Water that has been subjected to various purification treatments is supplied from the liquid supply line 1 by the liquid supply pump 2 and the dialysis stock solution supplied by the stock solution pump 3 and the mixing tank 4
Are mixed to form a dialysate having a constant concentration and sent to the double pump 5. Acetate dialysate or biker dialysis solution is usually used for dialysis treatment. In case of acetate dialysis, one dialysis solution is diluted and used, but in case of biker dialysis, two kinds of solution are diluted and mixed for use. Further, another set of the undiluted solution pump 3 and the mixing tank 4 is required, but they are omitted in FIG. The dual pump 5 supplies the diluted dialysate to the dialyzer 7 via the liquid supply line 6, and sucks an equal amount of dialysate waste liquid from the dialyzer 7 via the drain line 8 to the outside from the drain line 9. Drain. On the other hand, the dewatering pump 11 sends the dialysis waste liquid from the drainage line 8 to the drainage line 9 through the drainage line 12 and discharges it to the outside. As described above, since the amount of dialysate delivered by the dual pump 5 and the amount of dialysate waste that is aspirated are equal, the amount delivered by the water removal pump 11 was aspirated from the blood of the patient M through the dialysis membrane of the dialyzer 7. The amount of water, that is, the amount of water removed, is equal to the amount of water removed, and by controlling the water removal pump 11, water removal, which is one purpose of dialysis treatment, can be controlled.

In such a hemodialysis apparatus, the following operations are performed when cleaning and disinfecting the liquid circuit after completion of dialysis treatment. First, during cleaning / disinfection, the dialyzer 7 is removed, and the bypass coupler 13 is connected instead. The stock solution connection port 21 is connected to a rinse port 18 provided on the drain line 9 which is removed from the external stock solution tank. These connections are shown in dashed lines in FIG. And water supply valve 1
4. Close the bypass valve 16 and open the drain valve 15 and the chemical liquid valve 17. Further, by operating only the water removal pump 11, the liquid feed pump 2, the liquid feed pump 10, the double pump 5,
The stock solution pump 3 is stopped. With this setting, the dewatering pump 11 discharges the dialysis waste liquid remaining in the drainage line 8, but at this time, since the liquid supply line 6 and the drainage line 8 have a negative pressure, only the amount of liquid to be drained is discharged. The concentrated chemical liquid for cleaning / disinfection is sucked from the chemical liquid tank 20 through the chemical liquid line 19. The dewatering pump 11 is a quantitative pump, and by this operation, the amount necessary for the target concentration (calculated from the total volume of the dialysate circuit) can be accurately sucked. Further, the volumes of the water removal line 12 and the drainage line 9 are larger than the concentrated chemical liquid amount required for the target concentration, and the inhaled chemical liquid is not discharged to the outside.

Next, the drain valve 15 and the chemical liquid valve 17 are closed, the bypass valve 16 is opened to open the connection line 23, and all pumps are operated. At this time, the dialysate circuit becomes a closed circuit and the remaining dialysate and drug solution begin to circulate in the circuit while being mixed. And all pumps and lines can be disinfected and cleaned. Although one embodiment of the present invention has been described above, what is added to the present invention in addition to the components necessary for normal dialysis treatment are only a few valves and pipes as will be apparent from the above description. The chemical solution supply mechanism can be composed of only a limited number of parts. Moreover, since there is no leakage of the chemical liquid, the consumption of the concentrated chemical liquid can be suppressed to the minimum. It should be noted that the disinfecting / cleaning concentrated chemical liquid described in the above description is usually sodium hypochlorite or acetic acid,
Various chemical solutions such as other inorganic or organic acid solutions and chlorine-based antiseptic solutions are applied within the scope of the purpose.

[0013]

According to the present invention, in a hemodialysis device,
As compared with the conventional method, cleaning and disinfection of the dialysate circuit can be performed more efficiently and simply, and as a result, more reliable dialysis treatment can be provided to the patient.

[Brief description of drawings]

FIG. 1 is a diagram showing an embodiment of a hemodialysis apparatus of the present invention.

[Explanation of sign]

 1, 6 Liquid supply line 2, 10 Liquid feed pump 3 Undiluted liquid pump 4 Mixing tank 5 Complex pump 7 Dialyzer 8, 9 Drainage line 11 Water removal pump 12 Water removal line 13 Bypass coupler 14 Water supply valve 15 Drainage valve 16 Bypass valve 17 Chemical Liquid Valve 18 Rinse Port 19 Chemical Liquid Line 20 Chemical Liquid Tank 21 Undiluted Liquid Connection Port 22 Blood Circuit 23 Bypass Line M Patient

Claims (1)

[Claims] 1. A liquid supply line provided with a liquid supply pump for supplying dialysate to a dialyzer, a drainage line for discharging dialysate waste liquid from the dialyzer, and the drainage pump. A water removal line whose flow rate is controlled by a water removal pump by bypassing the liquid supply line, a chemical liquid supply line connected to the liquid supply line or the liquid discharge line, an external connection end of the liquid supply line, and the liquid discharge line. And a bypass line connecting the external connection end of the drainage line to the drainage line with the external connection end of the liquid supply line closed and the external connection end of the drainage line open. A predetermined concentrated chemical liquid is introduced from the chemical liquid supply line into the liquid supply line or the drainage line by operating a pump, and then the bypass line is opened to remove the concentrated chemical liquid introduced into the bypass line. Supplying a drug solution to a hemodialysis device characterized by diluting a concentrated drug solution to a predetermined concentration by circulating the solution through a pass line, the drain line and the water removal line to mix with the remaining liquid. how to.