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SANHO KAGAKU KENKYUSHO KK
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SANHO KAGAKU KENKYUSHO KK
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Application filed by SANHO KAGAKU KENKYUSHO KKfiledCriticalSANHO KAGAKU KENKYUSHO KK
Priority to JP4108184ApriorityCriticalpatent/JPS60184058A/ja
Publication of JPS60184058ApublicationCriticalpatent/JPS60184058A/ja
Publication of JPH0533216B2publicationCriticalpatent/JPH0533216B2/ja
Stereospecific alkylation of the Schiff base ester of alanine with 2-substituted-(E)-and-(Z)-vinyl bromides. An efficient synthesis of 2-methyl-(E)-3, 4-didehydroglutamic acid, a potent substrate-induced irreversible inhibitor of L-glutamate-1-decarboxylase