JPH05212124A - 経皮薬剤施与装置 - Google Patents

経皮薬剤施与装置

Info

Publication number
JPH05212124A
JPH05212124A JP4265289A JP26528992A JPH05212124A JP H05212124 A JPH05212124 A JP H05212124A JP 4265289 A JP4265289 A JP 4265289A JP 26528992 A JP26528992 A JP 26528992A JP H05212124 A JPH05212124 A JP H05212124A
Authority
JP
Japan
Prior art keywords
electrodes
liquid
skin
patient
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4265289A
Other languages
English (en)
Japanese (ja)
Inventor
Josef Gross
ジョセフ・グロス
Shlomo Zucker
シュロモ・ザッカー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SI SCIENT INNOV Ltd
SI Scientific Innovations Ltd
Original Assignee
SI SCIENT INNOV Ltd
SI Scientific Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SI SCIENT INNOV Ltd, SI Scientific Innovations Ltd filed Critical SI SCIENT INNOV Ltd
Publication of JPH05212124A publication Critical patent/JPH05212124A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP4265289A 1991-09-12 1992-09-07 経皮薬剤施与装置 Pending JPH05212124A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US759006 1991-09-12
US07/759,006 US5356632A (en) 1991-09-12 1991-09-12 Transdermal drug delivery device

Publications (1)

Publication Number Publication Date
JPH05212124A true JPH05212124A (ja) 1993-08-24

Family

ID=25054021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4265289A Pending JPH05212124A (ja) 1991-09-12 1992-09-07 経皮薬剤施与装置

Country Status (8)

Country Link
US (1) US5356632A (fr)
EP (1) EP0532451B1 (fr)
JP (1) JPH05212124A (fr)
AT (1) ATE133078T1 (fr)
DE (1) DE69207688T2 (fr)
DK (1) DK0532451T3 (fr)
ES (1) ES2082423T3 (fr)
GR (1) GR3019575T3 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536613A (ja) * 2005-04-22 2008-09-11 イーシーポイント メディカル インコーポレイテッド Dc組織処置
JP2017501803A (ja) * 2013-12-20 2017-01-19 ロレアル 貯留器を有するイオン導入デバイス

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5533995A (en) * 1991-11-13 1996-07-09 Elan Corporation, Plc Passive transdermal device with controlled drug delivery
US6009345A (en) * 1992-08-17 1999-12-28 Genetronics, Inc. Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
WO1996031200A1 (fr) * 1995-04-07 1996-10-10 Novartis Ag Systeme transdermique pourvu d'electrodes servant de systeme d'initialisation
EP1131131A1 (fr) 1995-04-23 2001-09-12 Electromagnetic Bracing Systems, Inc. Systeme et procede d'administration transdermique active de medicament
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
US5954685A (en) * 1996-05-24 1999-09-21 Cygnus, Inc. Electrochemical sensor with dual purpose electrode
US6650934B2 (en) 1996-12-17 2003-11-18 Alza Corp Polymeric foam reservoirs for an electrotransport delivery device
US6246904B1 (en) 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
US6157858A (en) * 1996-12-26 2000-12-05 Elan Pharma International Limited Device for the delivery of a substance to a subject and improved electrode assembly
US6078842A (en) * 1997-04-08 2000-06-20 Elan Corporation, Plc Electrode and iontophoretic device and method
TW368420B (en) * 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
DE69806794T2 (de) * 1997-11-04 2003-03-13 Genetronics, Inc. Kombinierte elektroporation-und iontophoresevorrichtung zur medikament-und genverabreichung
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
DE69921090T2 (de) 1998-01-28 2005-02-17 Alza Corp., Mountain View Konfigurierte Elektrodenanordnung mit verbesserter elektrischer Leitung
DE19816143A1 (de) * 1998-04-09 1999-10-21 Fischer Wilfried Transdermales Applikationssystem (TDS) mit Elektrodenraster
US6757560B1 (en) 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
JP4421113B2 (ja) * 1998-08-31 2010-02-24 トラヴァンティ ファーマ インコーポレイテッド 制御投与薬物送達システム
US6475514B1 (en) 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6713291B2 (en) * 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
US6337328B1 (en) 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
US6421561B1 (en) * 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
FR2830766B1 (fr) 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
US6916120B2 (en) * 2002-01-30 2005-07-12 Adc Telecommunications, Inc. Fiber optic connector and method
FR2835755A1 (fr) * 2002-02-13 2003-08-15 Metalarc Biomedical Dispositif d'electrolipolyse pour le traitement de la cellulite
EP1457233B1 (fr) 2003-03-12 2007-07-11 Novosis AG Système d'administration de médicaments transdermique avec electrode à mailles
US7477939B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of treating a wound with galvanic generated electricity
US7479133B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Methods of treating acne and rosacea with galvanic generated electricity
US8734421B2 (en) * 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US7480530B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
US7477941B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of exfoliating the skin with electricity
DK1644076T3 (da) * 2003-06-30 2014-02-03 Johnson & Johnson Consumer Topisk sammensætning til behandling af akne og rosacea med galvanisk genereret elektricitet
US7486989B2 (en) * 2003-06-30 2009-02-03 Johnson & Johnson Consumer Companies, Inc. Device for delivery of oxidizing agents to barrier membranes
US7477938B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Cosumer Companies, Inc. Device for delivery of active agents to barrier membranes
US7507228B2 (en) 2003-06-30 2009-03-24 Johnson & Johnson Consumer Companies, Inc. Device containing a light emitting diode for treatment of barrier membranes
US7476222B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of reducing the appearance of pigmentation with galvanic generated electricity
US7477940B2 (en) * 2003-06-30 2009-01-13 J&J Consumer Companies, Inc. Methods of administering an active agent to a human barrier membrane with galvanic generated electricity
US20050038473A1 (en) * 2003-07-14 2005-02-17 Dov Tamarkin Device and method for the treatment of pilosebaceous disorders
US20050226921A1 (en) * 2004-04-13 2005-10-13 Kortzebom Robert N Non-invasive analysis and controlled dosage transdermal active patch
FR2869120B1 (fr) * 2004-04-15 2006-08-25 World Wide Watch Montre interactive.
US20060088581A1 (en) * 2004-09-22 2006-04-27 Thomas Blaszczykiewicz Device for delivery of therapeutic agent
US8512288B2 (en) 2006-08-23 2013-08-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US20080097291A1 (en) 2006-08-23 2008-04-24 Hanson Ian B Infusion pumps and methods and delivery devices and methods with same
US7905868B2 (en) 2006-08-23 2011-03-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8277415B2 (en) 2006-08-23 2012-10-02 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8137314B2 (en) * 2006-08-23 2012-03-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with compressible or curved reservoir or conduit
US9233203B2 (en) 2005-05-06 2016-01-12 Medtronic Minimed, Inc. Medical needles for damping motion
US8840586B2 (en) 2006-08-23 2014-09-23 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US8287923B2 (en) * 2005-06-10 2012-10-16 Medical College Of Georgia Research Institute, Inc. Compositions and methods for treating immune disorders
US9446017B2 (en) 2005-08-11 2016-09-20 Augusta University Research Institute, Inc. Compositions and methods for treating herpes simplex virus
EP1993633B1 (fr) 2006-02-09 2016-11-09 Deka Products Limited Partnership Systemes de distribution de fluide de pompage et procedes utilisant un ensemble d'application de force
US7828764B2 (en) 2006-08-23 2010-11-09 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7736338B2 (en) 2006-08-23 2010-06-15 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US7794434B2 (en) 2006-08-23 2010-09-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7811262B2 (en) 2006-08-23 2010-10-12 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US9114133B2 (en) 2006-08-25 2015-08-25 U.S. Dept. Of Veterans Affairs Method of improving diastolic dysfunction
US8613725B2 (en) 2007-04-30 2013-12-24 Medtronic Minimed, Inc. Reservoir systems and methods
US7959715B2 (en) 2007-04-30 2011-06-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir air bubble management
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
US8597243B2 (en) 2007-04-30 2013-12-03 Medtronic Minimed, Inc. Systems and methods allowing for reservoir air bubble management
DK2146760T3 (en) 2007-04-30 2019-01-28 Medtronic Minimed Inc FILLING OF RESERVOIR, BUBBLE MANAGEMENT AND DELIVERY SYSTEMS FOR INFUSION MEDIA AND PROCEDURES
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8434528B2 (en) 2007-04-30 2013-05-07 Medtronic Minimed, Inc. Systems and methods for reservoir filling
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
JP2010529897A (ja) * 2007-06-15 2010-09-02 ニトリツク・バイオ・セラピユーテイクス・インコーポレーテツド 動電学的薬剤配送の電流集中緩和方法とシステム
US20080312580A1 (en) * 2007-06-15 2008-12-18 Transport Pharmaceuticals, Inc. Current concentration system and method for electrokinetic delivery of medicaments
DE112008002309A5 (de) * 2007-06-25 2010-05-27 Acino Ag Elektrophoretisches transdermales Applikationssystem
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8150525B2 (en) 2008-08-27 2012-04-03 Johnson & Johnson Consumer Companies, Inc. Treatment of hyperhydrosis
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (fr) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Dispositif de mesure de la concentration d'un solute et procedes associes
EP2365831B2 (fr) * 2008-09-24 2017-01-04 3M Innovative Properties Company Hydrogels comprenant un élément de libération
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
EP3284494A1 (fr) 2009-07-30 2018-02-21 Tandem Diabetes Care, Inc. Système de pompe à perfusion portable
US20130017188A1 (en) 2009-07-31 2013-01-17 The Brigham And Women's Hospital, Inc. Modulation of sgk1 expression in th17 cells to modulate th17-mediated immune responses
WO2011059915A1 (fr) * 2009-11-13 2011-05-19 Johnson & Johnson Consumer Companies, Inc. Dispositif galvanique pour le traitement de la peau
US8969327B2 (en) 2010-04-08 2015-03-03 Emory University Substituted androst-4-ene diones
DE102010024558B4 (de) 2010-06-22 2016-04-21 Amw Gmbh Transdermales therapeutisches System mit Elektroden
CA2830069C (fr) 2011-03-20 2019-11-12 The University Of British Columbia Agent therapique destine a l'emphyseme et a la bpco
EP2704726B1 (fr) 2011-05-04 2018-10-31 Trustees of Boston University Stimulation de la force proton motrice pour potentialiser des antibiotiques aminoglycosides contre bactéries persistantes
WO2013003697A1 (fr) 2011-06-30 2013-01-03 Trustees Of Boston University Méthode de régulation de croissance tumorale, d'angiogenèse et de métastase à l'aide du récepteur 1 riche en proline et contenant une immunoglobuline (igpr-1)
EP2543370A1 (fr) 2011-07-06 2013-01-09 Georgia Health Sciences University Research Institute, Inc. Compositions et procédés pour traiter le virus de l'herpès simplex
US9243037B2 (en) 2011-11-10 2016-01-26 Trustees Of Boston College Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US20150366890A1 (en) 2013-02-25 2015-12-24 Trustees Of Boston University Compositions and methods for treating fungal infections
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
CA2924141C (fr) 2013-08-22 2022-06-07 The General Hospital Corporation Derives d'oxazole et de thiazole substitues par 5-amino 4-cyano utilisesen tant qu'inhibiteurs de la 12/15-lipoxygenase-humaine
CA2922361C (fr) 2013-08-29 2022-07-12 Trustees Of Boston University Produits metaboliques intermediaires pour potentialiser des antibiotiques aminoglycosides dans des infections bacteriennes
CN103499519A (zh) * 2013-10-10 2014-01-08 河南科技大学 一种复合物理场经皮给药实验装置
DK3191170T3 (da) * 2014-09-08 2022-05-16 Fastmeditalia S R L Plaster, der kan frembringe mikrostrømme
EP3191041B1 (fr) 2014-09-10 2022-06-08 C. R. Bard, Inc. Pansement protecteur pour dispositif médical placé sur la peau
WO2016196664A1 (fr) 2015-06-01 2016-12-08 Cedars-Sinai Medical Center Procédés et utilisation de composés qui se lient à rela de nf-kb
WO2017017631A2 (fr) 2015-07-28 2017-02-02 Vyome Biosciences Pvt. Ltd. Agents thérapeutiques antibactériens et agents prophylactiques
WO2020077013A1 (fr) * 2018-10-09 2020-04-16 Battelle Memorial Institute Conducteurs ioniques mixtes: dispositifs, systèmes et procédés d'utilisation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
AT371342B (de) * 1978-10-12 1983-06-27 Tapper Robert Elektrodenanordnung zur lokalen einleitung von gleichstrom in die haut eines lebenden koerpers, insbesondere zur iontophoretischen behandlung
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4486194A (en) * 1983-06-08 1984-12-04 James Ferrara Therapeutic device for administering medicaments through the skin
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4940456A (en) * 1987-02-10 1990-07-10 Dan Sibalis Electrolytic transdermal delivery of proteins
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
WO1990004434A1 (fr) * 1988-10-26 1990-05-03 Kabushiki Kaisya Advance Interface pour endermose electrique
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536613A (ja) * 2005-04-22 2008-09-11 イーシーポイント メディカル インコーポレイテッド Dc組織処置
JP2017501803A (ja) * 2013-12-20 2017-01-19 ロレアル 貯留器を有するイオン導入デバイス

Also Published As

Publication number Publication date
DE69207688D1 (de) 1996-02-29
DK0532451T3 (da) 1996-03-18
EP0532451B1 (fr) 1996-01-17
EP0532451A1 (fr) 1993-03-17
DE69207688T2 (de) 1996-05-30
ES2082423T3 (es) 1996-03-16
US5356632A (en) 1994-10-18
GR3019575T3 (en) 1996-07-31
ATE133078T1 (de) 1996-02-15

Similar Documents

Publication Publication Date Title
JPH05212124A (ja) 経皮薬剤施与装置
AU2005225129B2 (en) Electrokinetic delivery device
CA1226777A (fr) Applicateur de medicament par voie transdermique
EP0419820B1 (fr) Electrode d'iontophorèse
US4708716A (en) Transdermal drug applicator
EP0796126B1 (fr) Dispositif d'apport medicamenteux par electrotransport et son procede de fabrication
JP2807800B2 (ja) 経皮質薬剤投与アプリケータ
US5879322A (en) Self-contained transdermal drug delivery device
US4808152A (en) System and method for controlling rate of electrokinetic delivery of a drug
US5693024A (en) Iontophoretic drug delivery system, including method for determining hydration of patch
US20040193089A1 (en) Transdermal delivery system (TDS) with electrode network
ES2104607T3 (es) Aparato para liberacion iontoforetica de farmacos.
JP2005506158A5 (fr)
KR20050115313A (ko) 가요성의 전도성 소자를 갖는 저장소 하우징을 구비하는전기전송 장치
JPH0456627B2 (fr)
JPH0236885A (ja) イオン浸透療法装置
IE75058B1 (en) Electrically assisted transdermal transport device and method for renewing the device
JP2816886B2 (ja) 生体通電装置
JP2865422B2 (ja) イオン浸透療法装置および速度調整膜を用いた方法
JPS63500010A (ja) 薬剤の動電学的供給速度を制御する装置及び方法
WO2022255232A1 (fr) Élément d'introduction d'ions de batterie biologique et matériau de base de type feuille
KR200393037Y1 (ko) 이온 도입 치료기