ES2104607T3 - Aparato para liberacion iontoforetica de farmacos. - Google Patents

Aparato para liberacion iontoforetica de farmacos.

Info

Publication number
ES2104607T3
ES2104607T3 ES90908786T ES90908786T ES2104607T3 ES 2104607 T3 ES2104607 T3 ES 2104607T3 ES 90908786 T ES90908786 T ES 90908786T ES 90908786 T ES90908786 T ES 90908786T ES 2104607 T3 ES2104607 T3 ES 2104607T3
Authority
ES
Spain
Prior art keywords
drug
plane
electrodes
optionally
delivered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908786T
Other languages
English (en)
Inventor
Ronald E Laprade
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noven Pharmaceuticals Inc
Original Assignee
Noven Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharmaceuticals Inc filed Critical Noven Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2104607T3 publication Critical patent/ES2104607T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)

Abstract

UN DISPOSITIVO IONTOFORETICO PARA LA DISTRIBUCION DE UN MEDICAMENTO COMPRENDE UN SOPORTE FLEXIBLE NO CONDUCTOR (12); PRIMERO (16) Y SEGUNDO (18) ELECTRODO FORMADOS SUBSTANCIALMENTE POR MATERIAL NO IONIZANTE EN UN PLANO, UNA CARA DEL PLANO QUE SE UNE OPCIONALMENTE AL SOPORTE FLEXIBLE OPCIONALMENTE (12), Y LA OTRA CARA DEL PLANO QUE SE ADAPTA PARA FIJARSE A UNA CARA DE UNA CAPA ELECTRICAMENTE CONDUCTORA Y FLEXIBLE QUE CONTIENE EL MEDICAMENTO A DISTRIBUIR; UNA FUENTE (34) DE CORRIENTE ELECTRICA Y UN CIRCUITO INTEGRADO (30) QUE CONTIENE UN MEDIO PARA INVERTIR LA POLARIDAD DE LOS DOS ELECTRODOS. EL DISPOSITIVO PUEDE INCLUIR ADICIONALMENTE LA CAPA CONDUCTORA QUE CONTIENE EL MEDICAMENTO A ADMINISTRAR, UNIDO AL PLANO DE LOS DOS ELECTRODOS. SE PUEDE DISPONER OPCIONALMENTE UNA MEMBRANA DE INTERCAMBIO DE IONES ENTRE LOS DOS ELECTRODOS Y LA CAPA QUE CONTIENE EL MEDICAMENTO. EL CIRCUITO INTEGRADO (30) PUEDE CONTENER OPCIONALMENTE MEDIOS DE IMPULSOS O MEDIOS DE VARIACION DE CORRIENTE O AMBOS PARA VARIARLA CANTIDAD DE CORRIENTE SUMINISTRADA PARA UN PERIODO DE TIEMPO DETERMINADO O EN LA CANTIDAD ABSOLUTA.
ES90908786T 1988-11-16 1990-05-30 Aparato para liberacion iontoforetica de farmacos. Expired - Lifetime ES2104607T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/271,600 US5006108A (en) 1988-11-16 1988-11-16 Apparatus for iontophoretic drug delivery
PCT/US1990/003015 WO1991018642A1 (en) 1988-11-16 1990-05-30 Method and apparatus for iontophoretic drug delivery
SG1996008700A SG45441A1 (en) 1988-11-16 1990-05-30 Method and apparatus for iontophoretic delivery system

Publications (1)

Publication Number Publication Date
ES2104607T3 true ES2104607T3 (es) 1997-10-16

Family

ID=37309481

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908786T Expired - Lifetime ES2104607T3 (es) 1988-11-16 1990-05-30 Aparato para liberacion iontoforetica de farmacos.

Country Status (10)

Country Link
US (1) US5006108A (es)
EP (1) EP0531284B1 (es)
AT (1) ATE155347T1 (es)
AU (1) AU644793B2 (es)
CA (1) CA2002849C (es)
DE (1) DE69031083T2 (es)
DK (1) DK0531284T3 (es)
ES (1) ES2104607T3 (es)
SG (1) SG45441A1 (es)
WO (1) WO1991018642A1 (es)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
ATE177959T1 (de) * 1989-05-10 1999-04-15 Drug Delivery Systems Inc Elektrisches system mit mehreren signalen zur transdermalen medikamentenverabreichung
CA2071321C (en) * 1989-05-10 2000-12-12 Dan Sibalis Multi-signal electrical transdermal drug applicator
US5320597A (en) * 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
US6600950B1 (en) * 1990-11-01 2003-07-29 Robert Tapper Iontophoretic treatment system
US6223076B1 (en) 1990-11-01 2001-04-24 Robert Tapper Sweat control system
US5224927A (en) * 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US6238381B1 (en) * 1990-11-01 2001-05-29 Robert Tapper Iontophoretic treatment system
US6582416B2 (en) 1990-11-01 2003-06-24 Robert Tapper Iontophoretic treatment system
US6575957B1 (en) * 1990-11-01 2003-06-10 Robert Tapper Iontophoretic treatment system
US6235013B1 (en) 1990-11-01 2001-05-22 Robert Tapper Iontophoretic treatment system
US6139537A (en) * 1990-11-01 2000-10-31 Tapper; Robert Iontophoretic treatment system
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device
JP2570823Y2 (ja) * 1991-12-06 1998-05-13 久光製薬株式会社 プラスター形状の低周波治療器
US5294770A (en) * 1992-01-14 1994-03-15 Alza Corporation Laser tablet treatment system with dual access to tablet
US5380271A (en) * 1992-09-24 1995-01-10 Alza Corporation Electrotransport agent delivery device and method
US5443441A (en) * 1993-03-05 1995-08-22 De Claviere; Anne Marie Apparatus and method for transdermal delivery of cosmetic compositions
US5415629A (en) * 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
DE69429603T2 (de) * 1993-09-22 2002-08-14 Hisamitsu Pharmaceutical Co Iontophoresematrix
US20050159699A1 (en) * 1993-09-30 2005-07-21 Vyteris, Inc. Iontophoretic drug delivery device and reservoir and method of making same
JPH09503136A (ja) * 1993-09-30 1997-03-31 ベクトン・ディッキンソン・アンド・カンパニー イオン導入ドラッグデリバリーシステム及び方法
AU7845494A (en) * 1993-09-30 1995-04-18 Becton Dickinson & Company Iontophoretic device, reservoir and method of making
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
US5771890A (en) * 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
JP3565903B2 (ja) * 1994-06-25 2004-09-15 久光製薬株式会社 イオントフォレーシス用電極構造体
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5551953A (en) * 1994-10-31 1996-09-03 Alza Corporation Electrotransport system with remote telemetry link
FR2726769B1 (fr) * 1994-11-16 1997-01-31 Lhd Lab Hygiene Dietetique Dispositif ionophoretique d'administration transdermique de medicaments et ensemble jetable formant partie d'un tel dispositif
US5697896A (en) * 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5562607A (en) * 1995-01-18 1996-10-08 Alza Corporation Electrotransport device having reusable controller power saver
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
US5843014A (en) * 1995-03-24 1998-12-01 Alza Corporation Display for an electrotransport delivery device
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US5978701A (en) * 1995-06-02 1999-11-02 Alza Corporation Electrotransport device with separable controller and drug unit and method of setting controller output
US6216033B1 (en) 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
BR9609358A (pt) 1995-06-05 1999-05-18 Alza Corp Dispositivo para distribuição transdérmica por eletrotransporte fentanil e sufentanil
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
US6425892B2 (en) 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
ZA964320B (en) * 1995-06-05 1997-01-13 Alza Corp Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6355025B1 (en) 1995-06-07 2002-03-12 Alza Corporation Adjustable electrotransport drug delivery using a fixed output controller
AU7286996A (en) * 1995-10-18 1997-05-07 Ciba-Geigy Ag Thermopile powered transdermal drug delivery device
USD384745S (en) * 1996-01-23 1997-10-07 Alza Corporation Electrotransport drug delivery system
US6086572A (en) * 1996-05-31 2000-07-11 Alza Corporation Electrotransport device and method of setting output
US5941843A (en) * 1996-07-12 1999-08-24 Empi, Inc. Iontophoresis electrode
US5857993A (en) * 1996-07-12 1999-01-12 Empi, Inc. Process of making an iontophoresis electrode
US5871461A (en) * 1996-07-12 1999-02-16 Empi, Inc. Method of making an iontophoresis electrode
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
AU4335897A (en) * 1997-09-08 1999-03-29 Becton Dickinson & Company Iontophoretic delivery of buprenorphine
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
US6295469B1 (en) 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
AU1622999A (en) 1997-12-17 1999-07-05 Alza Corporation Iontophoresis with programmed adjustment of electric current
KR100245835B1 (ko) * 1998-02-10 2000-06-01 이양희 습포제
US6162460A (en) * 1998-03-10 2000-12-19 Lee; Yang-Hee Poultice
US6949081B1 (en) * 1998-08-26 2005-09-27 Non-Invasive Technology, Inc. Sensing and interactive drug delivery
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6858018B1 (en) 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
BR0008123A (pt) 1999-02-10 2001-11-13 Gmp Drug Delivery Inc Dispositivo baseado em emplastro para aumentar aliberação local de um agente de tratamento paradentro de tecidos alvo, e, processo de liberaçãode um agente de tratamento para dentro detecidos alvo de uma vesìcula corporal
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
JP2000300682A (ja) * 1999-04-23 2000-10-31 Hisamitsu Pharmaceut Co Inc イオントフォレーシス用デバイス
CA2400325A1 (en) 2000-02-18 2001-08-23 University Of Utah Research Foundation Methods for delivering agents using alternating current
WO2001060448A1 (en) 2000-02-18 2001-08-23 University Of Utah Research Foundation Methods for extracting substances using alternating current
US6905016B2 (en) 2000-03-14 2005-06-14 Noven Pharmaceuticals, Inc. Packaging system for transdermal drug delivery systems
KR100822339B1 (ko) 2000-09-11 2008-04-16 알자 코포레이션 경피 전기운반 장치 및 그 제조 방법
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
EP1463560B1 (en) * 2001-12-19 2009-02-11 ALZA Corporation Reservoir housing having a conductive region integrally formed therein
CA2471459A1 (en) 2001-12-20 2003-07-03 Alza Corporation Electrotransport device having an integrally molded reservoir housing
TR200200942A2 (tr) * 2002-04-08 2004-02-23 Tuncer De��M �. Üre ölçer/üre saati:insan kanındaki ürenin ters iyontoforez ile, kan veya biyolojik örnek alınmadan tespiti.
AU2004227851A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Electrotransport device having a reservoir housing having a flexible conductive element
US20040267283A1 (en) * 2003-06-25 2004-12-30 Daniela Mavor Method, device and kit for body decoration
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
EP1893278A2 (en) * 2005-06-03 2008-03-05 Trans-Dermal Patents Company, LLC Agent delivery system
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
US20090214625A1 (en) * 2005-07-15 2009-08-27 Mizuo Nakayama Drug delivery patch
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20100016781A1 (en) * 2005-08-29 2010-01-21 Mizuo Nakayama Iontophoresis device selecting drug to be administered on the basis of information form sensor
WO2007029611A1 (ja) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. イオントフォレーシス装置
WO2007032446A1 (ja) * 2005-09-15 2007-03-22 Tti Ellebeau, Inc. ロッド型イオントフォレーシス装置
BRPI0616166A2 (pt) * 2005-09-16 2011-06-07 Tti Ellebeau Inc dispositivo de iontoforese do tipo de cateter
WO2007038028A1 (en) * 2005-09-28 2007-04-05 Tti Ellebeau, Inc. Iontophoresis apparatus and method to deliver active agents to biological interfaces
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
JPWO2007037476A1 (ja) * 2005-09-30 2009-04-16 Ｔｔｉ・エルビュー株式会社 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070093787A1 (en) * 2005-09-30 2007-04-26 Transcutaneous Technologies Inc. Iontophoresis device to deliver multiple active agents to biological interfaces
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
WO2007037475A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
JP4804904B2 (ja) * 2005-12-09 2011-11-02 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置包装品
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US20080033398A1 (en) * 2005-12-29 2008-02-07 Transcutaneous Technologies Inc. Device and method for enhancing immune response by electrical stimulation
KR100723424B1 (ko) * 2006-04-07 2007-05-30 삼성전자주식회사 세포 또는 바이러스의 농축 및 용해용 미세유동장치 및방법 및 상기 미세유동장치의 제조 방법
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
MX2009002321A (es) * 2006-09-05 2009-03-23 Tti Ellebeau Inc Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva.
KR20090106492A (ko) * 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
EP2101864A2 (en) * 2006-12-20 2009-09-23 ALZA Corporation Anode for electrotransport of cationic drug
CA2656086A1 (en) 2007-06-26 2008-12-31 Alza Corporation Methods and devices for transdermal electrotransport delivery of lofentanil and carfentanil
US20100312168A1 (en) * 2009-06-09 2010-12-09 Yoshimasa Yoshida Long life high capacity electrode, device, and method of manufacture
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
KR20160119093A (ko) * 2014-02-04 2016-10-12 로레알 적어도 2개의 구획부를 포함하는 전기 마스크
US20210162209A1 (en) * 2019-12-01 2021-06-03 Ubdevice Corp. Lightweight Iontophoresis Device

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
EP0060452B1 (en) * 1981-03-05 1985-10-23 Medtronic, Inc. Iontophoretic device
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
EP0225872B1 (en) * 1985-06-10 1992-09-02 Drug Delivery Systems Inc. Programmable control and mounting system for transdermal drug applicator
US4763659A (en) * 1985-08-21 1988-08-16 Spring Creek Institute, Inc. Dry electrode system for detection of biopotentials
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
JPS63102768A (ja) * 1986-10-20 1988-05-07 山之内製薬株式会社 イオントフオレ−シス用の新規プラスタ−構造体
US4927408A (en) * 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system

Also Published As

Publication number Publication date
CA2002849C (en) 1998-04-07
DE69031083D1 (de) 1997-08-21
AU644793B2 (en) 1993-12-23
SG45441A1 (en) 1998-01-16
EP0531284A1 (en) 1993-03-17
ATE155347T1 (de) 1997-08-15
US5006108A (en) 1991-04-09
EP0531284B1 (en) 1997-07-16
CA2002849A1 (en) 1990-05-16
AU5676790A (en) 1991-12-31
WO1991018642A1 (en) 1991-12-12
DE69031083T2 (de) 1998-02-12
DK0531284T3 (da) 1998-02-09

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