JPH0481964B2 - - Google Patents

Description

[Detailed description of the invention]

[Industrial Field of Application] The present invention relates to an external skin preparation that suppresses the stickiness characteristic of hydrophilic nonionic surfactants. [Prior Art] In skin preparations for external use, surfactants are widely blended for purposes such as solubilization, emulsification, and dispersion. In particular, nonionic surfactants are safe for the skin and eyes, and have a wide variety of structures. In addition, since it is possible to freely select the desired surfactant, it has become the most frequently used surfactant. However, among nonionic surfactants, hydrophilic ones have strong stickiness due to their hydrophilic group, polyoxyethylene (hereinafter abbreviated as POE). Naturally, this stickiness becomes more pronounced as the POE group becomes longer, and it is more noticeable in systems such as lotions where surface activity accounts for a large proportion of the ingredients. [Problems to be Solved by the Invention] In view of the above circumstances, the present inventors conducted extensive studies aimed at suppressing the stickiness of hydrophilic nonionic surfactants, and as a result, they identified both hydrophilic nonionic surfactants. It has been found that the above problem can be solved by blending a specific amount or more of the glycoside of hydroquinone, and the present invention has been completed. [Means for solving the problems] That is, the present invention uses ethylene oxide (hereinafter referred to as ethylene oxide).
EO) containing one or more hydrophilic nonionic surfactants and hydroquinone-β- in an amount (by weight) or more 5 times that of the hydrophilic nonionic surfactant.
This is an external skin preparation characterized by containing D-glucoside (generic name: arbutin). The hydrophilic nonionic surfactant used in the present invention is
It broadly includes general hydrophilic nonionic surfactants used in external skin preparations. Polyoxyethylene (below) that feels sticky
The number of moles added (called POE) is approximately 10 moles or more (nonionic surfactants with HLB of 7 or more correspond to this in terms of HLB of surfactants)
and up to 150 molar adduct positions are common. Specific examples of such hydrophilic nonionic surfactants include POE sorbitan monolaurate, POE sorbitan monooleate,
POE sorbitan fatty acid esters such as POE sorbitan monostearate, POE sorbitan tetraoleate, POE sorbitan monolaurate,
POE sorbitol fatty acid esters, POE sorbitol monooleate, POE sorbitol monostearate, POE sorbitol tetraoleate, POE
POE glycerin fatty acid esters such as glycerin monostearate, POE glycerin triisostearate, POE fatty acid esters such as POE monooleate, POE distearate, POE monodiolate ethylene glycol distearate,
POE lauryl ether, POE oleyl ether,
POE alkyl ethers such as POE behenyl ether, POE2-octyldodecyl ether, and POE cholestanol ether; POE alkyl phenyl ethers such as POE octyl phenyl ether and POE dinonyl phenyl ether; abbreviated)
Ether, POE/POP cetyl ether, POE/
POP2-decyltetradecyl ether, POE・
POP hydrogenated lanolin, POE/POP alkyl ether such as POE/POP glycerin ether, tetraPOE/tetraPOP ethylenediamine condensate,
POE castor oil derivatives such as POE castor oil, POE hydrogenated castor oil, POE hydrogenated castor oil monoisostearate, POE hydrogenated castor oil triisostearate, POE hydrogenated castor oil monopyroglutamic acid monoisostearate diester, POE sorbitol beeswax These include POE beeswax derivatives, POE lanolin derivatives, and POE propylene glycol fatty acid esters. In the present invention, one or more of the above hydrophilic nonionic surfactants are arbitrarily selected and used. When hydroquinone glycosides are not used in combination, the amount at which stickiness is felt is influenced by the type of hydrophilic nonionic surfactant, but it is approximately 0.1% by weight or more of the total amount of the skin external preparation, and the upper limit of the amount is It is generally up to about 10% by weight, preferably up to 3% by weight. In the present invention, a hydroquinone glycoside that is blended into a skin external preparation together with a hydrophilic nonionic surfactant to suppress the stickiness of the hydrophilic nonionic surfactant is represented by the following general formula (). In formula (), R is a D-glucose residue, which is β-bonded to hydroquinone. In order to suppress the stickiness of the hydrophilic nonionic surfactant, the above-mentioned arbutin needs to be blended in an amount at least 5 times the amount (weight) of the hydrophilic nonionic surfactant, although it depends on the type of the hydrophilic nonionic surfactant. be. Preferably, 6 in the total amount of the skin external preparation.
A good blend is ~20% by weight. The skin external preparations that can contain the hydrophilic nonionic surfactant and the above-mentioned arbutin include the usual skin external preparations, such as aqueous solutions, solubilized systems, emulsification systems, powder dispersion systems, water-oil two-layer systems, water-oil- Any type of base may be used, such as a three-layer powder type, and can be used in basic cosmetics such as lotions, milky lotions, creams, and packs, lipsticks,
There are a wide variety of cosmetics, including makeup cosmetics such as foundation, hair cosmetics such as shampoo, conditioner, and hair tonic, and quasi-drugs, but their true value is especially true when applied to transparent or translucent lotions. demonstrate. This is because lotions are generally water-alcohol based, and the amount of surfactant added accounts for a large portion of the total amount of ingredients, so they tend to feel particularly sticky after use. The external skin preparation of the present invention may contain moisturizers, thickeners, preservatives, antioxidants, sequestering agents, ultraviolet absorbers, powders, pigments, etc., as necessary, to the extent that the effects of the present invention are not impaired. Drugs, dyes, fragrances, etc. can be added. [Effects of the Invention] The skin external preparation of the present invention is an excellent skin external preparation that does not have the stickiness characteristic of hydrophilic nonionic surfactants and has good stability and safety. [Example] Next, the present invention will be explained in more detail with reference to Examples. The present invention is not limited to this in any way. Example 1 Toner lotion ethanol 20.0 1,3-butylene glycol 5.0 POE(15) oleyl ether 1.0 ethyl paraben 0.1 arbutin 6.0 Purified water Remainder (manufacturing method) POE oleyl ether and ethyl paraben are dissolved in a portion of ethanol. Separately, 1,3-butylene glycol and arbutin are dissolved in the remaining purified water and ethanol. The ethanol phase was added to the aqueous phase and solubilized to obtain a lotion. Comparative Example 1 Comparative Example 1 was obtained according to Example 1 except that the amount of arbutin in Example 1 was reduced to 3.0% by weight. Comparative Example 2 Comparative Example 2 was obtained according to Example 1 except that the amount of arbutin in Example 1 was reduced to 1.0% by weight. Usability (stickiness) of Example 1 and Comparative Examples 1 and 2
were determined and evaluated through actual use tests conducted by a panel specializing in women's beauty. (Judgment) A: Not sticky. B: Slightly sticky, but within a range that poses no problem in terms of usability. C: Sticky. D: Significantly sticky. The results are shown in Table-1. It is clear that arbutin prevents the stickiness of the hydrophilic nonionic surfactant and is particularly effective at 6% by weight or more.

[Table] Example 2 Lotion (A) Purified water Amount to make the total 100 Glycerin 2.0 Arbutin 1.0 1,3-butylene glycol 2.0 (B) Ethanol 15.0 Purified lecithin 0.02 POE (120) Hydrogenated castor oil 0.2 Fragrance 0.05 Methyparaben 0.1 (Production method) After uniformly dissolving the aqueous phase part (A) and the alcohol part (B), the alcohol part was added to the aqueous phase part for solubilization to obtain a lotion. Example 3 Aqueous essence (A) Purified water 1,3-butylene glycol 10.0 Maltitol 2.0 Arbutin 10.0 Dipropylene glycol 5.0 Carboxymethyl polymer 0.2 (B) Ethanol 10.0 POE (20) Glycerin monoisostearate 1.0 Vitamin E acetate 0.1 Fragrance 0.05 Oleyl alcohol 0.2 Methyl paraben 0.2 (C) Sodium hydroxide 0.1 (Production method) After uniformly dissolving the aqueous phase part of (A) and the alcohol part of (B), add the alcohol part to the aqueous phase part. was added to mix and solubilize, and then potassium hydroxide (C) was added to obtain essence. Example 4 Cream ointment Vaseline 20.0 Stearyl alcohol 15.0 Mokuro 15.0 POE(20)・POE(10) 1.0 Stearic acid monoglyceride 1.0 Arbutin 6.0 Ethanol 10.0 Purified water Residual

Claims (1)

[Claims] 1. It is characterized by containing one or more hydrophilic nonionic surfactants containing ethylene oxide and hydroquinone-β-D-glucoside in an amount (by weight) or more five times that of the hydrophilic nonionic surfactant. External skin preparation.