JPH0430949B2 - - Google Patents
Info
- Publication number
- JPH0430949B2 JPH0430949B2 JP19196084A JP19196084A JPH0430949B2 JP H0430949 B2 JPH0430949 B2 JP H0430949B2 JP 19196084 A JP19196084 A JP 19196084A JP 19196084 A JP19196084 A JP 19196084A JP H0430949 B2 JPH0430949 B2 JP H0430949B2
- Authority
- JP
- Japan
- Prior art keywords
- threo
- methoxyphenyl
- aminophenylthio
- hydroxy
- propionic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000003287 optical effect Effects 0.000 claims description 2
- NUSLQDOXLCYVTQ-UHFFFAOYSA-N 2-(2-methoxyphenyl)propanoic acid Chemical compound COC1=CC=CC=C1C(C)C(O)=O NUSLQDOXLCYVTQ-UHFFFAOYSA-N 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 18
- 150000003839 salts Chemical class 0.000 description 10
- 150000001875 compounds Chemical class 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000013078 crystal Substances 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- RQEUFEKYXDPUSK-UHFFFAOYSA-N 1-phenylethylamine Chemical compound CC(N)C1=CC=CC=C1 RQEUFEKYXDPUSK-UHFFFAOYSA-N 0.000 description 1
- XAVRCJUDEZXSEC-UHFFFAOYSA-N 2-(1,2-benzothiazepin-5-yl)-N,N-dimethylethanamine Chemical class CN(C)CCC1=CC=NSC2=C1C=CC=C2 XAVRCJUDEZXSEC-UHFFFAOYSA-N 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- -1 compound () 1,2-diphenylethylamine salt Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000000304 vasodilatating effect Effects 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19196084A JPS6169756A (ja) | 1984-09-13 | 1984-09-13 | スレオ−ｄ−２−ヒドロキシ−３−（２′−アミノフエニルチオ）−３−（４″−メトキシフエニル）−プロピオン酸の製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19196084A JPS6169756A (ja) | 1984-09-13 | 1984-09-13 | スレオ−ｄ−２−ヒドロキシ−３−（２′−アミノフエニルチオ）−３−（４″−メトキシフエニル）−プロピオン酸の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6169756A JPS6169756A (ja) | 1986-04-10 |
| JPH0430949B2 true JPH0430949B2 (enrdf_load_stackoverflow) | 1992-05-25 |
Family
ID=16283306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19196084A Granted JPS6169756A (ja) | 1984-09-13 | 1984-09-13 | スレオ−ｄ−２−ヒドロキシ−３−（２′−アミノフエニルチオ）−３−（４″−メトキシフエニル）−プロピオン酸の製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6169756A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225557A (en) * | 1988-05-10 | 1993-07-06 | Hoffmann-La Roche Inc. | Process for making optically active naphtho[1,2-b]thiazepin-4(5H)-ones |
-
1984
- 1984-09-13 JP JP19196084A patent/JPS6169756A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6169756A (ja) | 1986-04-10 |
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