JPH0428049Y2 - - Google Patents

Description

[Detailed Description of the Invention] A. Field of Application of the Technology The present invention relates to a blood analyzer, and more specifically to a blood sample injection mechanism.

B. Prior Art Blood analysis in the clinical field is performed by measuring gas components such as oxygen and carbon dioxide contained in blood, and electrolyte components such as sodium, potassium, and chlorine.

Conventionally, these gas components and electrolyte components were measured by
As shown in FIG. 2, this was carried out using a blood analyzer in which a flow cell A provided with a blood gas detection electrode and a flow cell B provided with an electrolyte detection electrode were arranged in series in a sample flow path.

According to this device, gas components and electrolyte components in blood can be simultaneously analyzed by injecting a blood sample once. However, when calibrating blood gas detection electrodes and electrolyte detection electrodes, different standard solutions are used, and two types of standard solutions with different components are injected alternately in two doses, which takes time. In addition, there was the inconvenience that a washing step was required to remove the influence of the previously injected standard solution.

In order to solve such problems,
As shown in Publication No. 31726, a branch pipe is connected to the discharge port of the sample suction pump, and a calibration sample supply source and measurement cell are connected to each branch pipe via a three-way valve, so that the same sample is supplied to each measurement cell. Analyzers have also been proposed that enable continuous supply of calibration gas and independent supply of calibration gas suitable for each measurement cell. However, since a common pump is used to pump the sample gas to each measurement cell, especially when the sample is a highly viscous fluid such as blood, the sample gas flowing into each measurement cell may be There is a problem in that the amount varies and large measurement errors occur.

C. Purpose The present invention was developed in view of these problems, and it is possible to reliably supply even a liquid sample with high viscosity such as blood to multiple measurement cells, and to create a standard suitable for each measurement cell. It is an object of the present invention to provide a novel blood analyzer that can supply liquids simultaneously and independently.

D. Structure of the device In other words, the feature of the present invention is that the same sample is temporarily stored in a channel that can be divided by a switching valve, and then the channel is divided by a switching valve and each channel is connected to a measurement cell. The suction pump installed in the unit aspirates the sample, and not only can the sample be reliably supplied to each measurement cell even with highly viscous liquids such as blood, but also the sample attached to each measurement cell during calibration work. The standard sample can be simultaneously and independently supplied to the measurement cell using a suction pump.

E. Embodiments Therefore, details of the present invention will be explained below based on illustrated embodiments.

FIGS. 1A and 1B show an embodiment of the present invention, in which reference numeral 1 is a flow path switching valve, and the first flow path 1a, second flow path 1b, third flow path It is configured to form a flow path 1c. 2 is
It is a pipe that communicates the sample inlet 4 and the cleaning liquid tank 5 with the switching valve 1 via the three-way valve 3, and is configured to have an internal volume sufficient to retain the amount of sample required for analysis. A pipe 6 communicates the discharge port 7 and the switching valve 1, and is configured to have an internal volume sufficient to retain the amount of sample required for analysis. 8
is an electrolyte measurement cell equipped with ion detection electrodes 8a, 8b, and 8c, and is configured by connecting one side to a switching valve 1 via a three-way valve 10 that communicates with a standard liquid tank 9, and the other side to a suction pump 11. has been done. 12 is a gas measurement cell provided with gas detection electrodes 12a, b, c,
One side is connected to the switching valve 1 via a three-way valve 14 that communicates with the standard liquid tank 13, and the other side is connected to a suction pump 15.

In this embodiment, the flow path switching valve 1 is operated to connect the pipes 2 and 6 to form a flow path from the sample injection port to the discharge port 7 (FIG. 1A). When such preparations are completed, a blood sample is injected from the sample injection port 4 using a syringe, and the sample passes from the pipe 2 through the flow path 1a of the switching valve 1 to the pipe 6.
The sample is collected in pipe 2 and pipe 6. At this point, operate the switching valve 1 to switch the pipe 2
A flow path extending from the electrolyte measurement cell 8 to the pipe 6
A flow path extending from the gas measuring cell 12 to the gas measuring cell 12 is formed (FIG. 2B). At this point, the sample suction pumps 11, 15
When activated, the samples stored in the pipes 2 and 6 flow in parallel into the measurement cells 8 and 12 through the channels 1b and 1c of the switching valve 1, respectively, and the samples contained in the blood flow into the measurement cells 8 and 12 in parallel. The electrolyte and gas components present are measured. When the measurement is finished,
With the handle in its original position, that is, with pipes 2 and 6 communicating (see Figure 1A), open the three-way valves 10 and 1.
4 to connect the measuring cell 8 and the standard liquid tank 9, and the measuring cell 12 and the standard liquid tank 13, and operate the suction pumps 11 and 15. As a result, the standard liquid tank 9
The standard solution in the tank flows into the electrolyte measurement cell 8, and the standard solution in the standard solution tank 13 flows into the gas measurement cell 12 at the same time, and the reference concentration is applied to the ion detection electrode and gas detection electrode provided in each cell. Electrolyte or gas components are applied in parallel and used for calibration.

Effects As explained above, in the present invention, the same sample is temporarily stored in a flow path that can be divided by a switching valve, and then the flow path is divided by a switching valve and communicated with each measurement cell. Since the sample is aspirated using the suction pump provided in the system, even with highly viscous liquids such as blood, the sample can be reliably supplied to each measurement cell, making it possible to not only achieve highly accurate measurements. During calibration work, a suction pump attached to each measurement cell can simultaneously and independently supply a standard sample suitable for each measurement cell to the measurement cell.

[Brief explanation of the drawing]

FIGS. 1A and 1B are block diagrams of an apparatus showing an embodiment of the present invention, and FIG. 2 is a block diagram showing an example of a conventional blood analyzer. 1...Flow path switching valve, 1a to 1c...Flow path, 2,
6... Pipe, 4... Sample injection port, 7... Discharge port, 8... Electrolyte measurement cell, 9, 13... Standard liquid tank, 12... Gas measurement cell, 4... Sample injection port...
….

Claims (1)

[Scope of utility model registration request] In the first flow path configuration, the sample inlet and the outlet are connected by a flow path having a volume necessary for analysis, and a first flow path switching valve is interposed in the middle of the flow path. The inlet and outlet are communicated, and the second
In the flow path configuration, one half of the flow path communicates with the first analysis flow path, the other half of the flow path communicates with the second analysis flow path, and each of the first and second analysis flow paths communicates with the first analysis flow path.
A blood analyzer that selectively connects a standard liquid tank and a measurement cell via a valve, and a suction pump connected downstream of each measurement cell.