JPH04161920A - Contact lens cleaning liquid - Google Patents
Contact lens cleaning liquidInfo
- Publication number
- JPH04161920A JPH04161920A JP28597190A JP28597190A JPH04161920A JP H04161920 A JPH04161920 A JP H04161920A JP 28597190 A JP28597190 A JP 28597190A JP 28597190 A JP28597190 A JP 28597190A JP H04161920 A JPH04161920 A JP H04161920A
- Authority
- JP
- Japan
- Prior art keywords
- contact lens
- weight
- lens cleaning
- monosaccharides
- active agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004140 cleaning Methods 0.000 title claims description 17
- 239000007788 liquid Substances 0.000 title 1
- 239000004094 surface-active agent Substances 0.000 claims abstract description 14
- 241000193830 Bacillus <bacterium> Species 0.000 claims abstract description 12
- 108090000790 Enzymes Proteins 0.000 claims abstract description 10
- 102000004190 Enzymes Human genes 0.000 claims abstract description 10
- 150000002772 monosaccharides Chemical class 0.000 claims abstract description 10
- 150000002016 disaccharides Chemical class 0.000 claims abstract description 7
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 4
- 239000002736 nonionic surfactant Substances 0.000 claims description 9
- 239000003945 anionic surfactant Substances 0.000 claims description 8
- 108090000787 Subtilisin Proteins 0.000 abstract description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 4
- 239000008103 glucose Substances 0.000 abstract description 4
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 abstract description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract description 2
- 102000004400 Aminopeptidases Human genes 0.000 abstract 1
- 108090000915 Aminopeptidases Proteins 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 description 14
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- 150000005215 alkyl ethers Chemical class 0.000 description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
- 125000005037 alkyl phenyl group Chemical group 0.000 description 4
- 239000000882 contact lens solution Substances 0.000 description 4
- 229940088598 enzyme Drugs 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 229910052708 sodium Inorganic materials 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- 108091005804 Peptidases Proteins 0.000 description 3
- 102000035195 Peptidases Human genes 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 239000003082 abrasive agent Substances 0.000 description 2
- 150000008051 alkyl sulfates Chemical class 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 description 2
- 235000011152 sodium sulphate Nutrition 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- YBUOVWJXFBWALW-UHFFFAOYSA-N O(CC(C)Cl)Cl Chemical compound O(CC(C)Cl)Cl YBUOVWJXFBWALW-UHFFFAOYSA-N 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 108090001109 Thermolysin Proteins 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
Landscapes
- Eyeglasses (AREA)
- Detergent Compositions (AREA)
Abstract
Description
本発明は、コンタクトレンズ、特に酸素透過性のコンタ
クトレンズの洗浄液に関するものである。The present invention relates to a cleaning solution for contact lenses, particularly oxygen permeable contact lenses.
コンタクトレンズは装用中に涙液成分がこびり付き、水
濡性が悪くなり、装用性に低下をきたす。
このような観点から、コンタクトレンズ洗浄液が用いら
れている訳であるが、それでも強固に付着してしまって
いる汚れの除去はできていない。
これら付着物の中でも、特に問題となるのはタンパク質
である。すなわち、タンパク質は一度付着してしまうと
、通常のコンタクトレンズ洗浄液では除去できない。
そこで、これらの汚れを除去する為に、週1回の割合で
タンパク質分解酵素を含むコンタクトレンズ洗浄液で洗
浄処理したり、あるいは研磨剤の入ったクリーナーで擦
り取る等の処理が行われている。
しかしながら、週1回の割合でタンパク質分解酵素を含
むコンタクトレンズ洗浄液を用いての処理は装用者にと
って非常に煩わしく、又、1週間かかってレンズ表面に
堆積し、かつ、変性してしまったタンパク質の汚れを、
週1回の割合の洗浄ではタンパク譬分解酵素を含むコン
タクトレンズ洗浄液を用いても充分には除去できない、
この為、現在では、研磨剤の入ったクリーナーで擦り取
ることが提案されている訳であるが、この作業も面倒で
あり、さらにはコンタクトレンズを損傷しかねない。While wearing contact lenses, tear fluid components become stuck, resulting in poor water wettability and reduced wearability. From this point of view, contact lens cleaning solutions are used, but even then, it is not possible to remove firmly adhered dirt. Among these deposits, proteins are particularly problematic. That is, once proteins adhere, they cannot be removed with normal contact lens cleaning solutions. Therefore, in order to remove these stains, treatments such as cleaning with a contact lens cleaning solution containing proteolytic enzymes once a week, or scrubbing with a cleaner containing abrasives are performed. However, treatment using a contact lens cleaning solution containing proteolytic enzymes once a week is very troublesome for the wearer, and it takes a week to remove the denatured proteins that accumulate on the lens surface. dirt,
If you wash your lenses once a week, even if you use a contact lens cleaning solution that contains proteolytic enzymes, you will not be able to remove them sufficiently.
For this reason, it is currently proposed to scrub the contact lenses with a cleaner containing abrasives, but this work is also troublesome and may even damage the contact lenses.
本発明の第1の目的は、装用性に優れたコンタクトレン
ズを提供することである。
本発明の第2の目的は、コンタクトレンズの装用性の維
持が簡単に行える手段を提供することである。
本発明の第3の目的は、コンタクトレンズを損傷させる
ことなく、コンタクトレンズの装用性の維持が簡単に行
える手段を提供することである。
上記本発明の目的は、単糖類及び二I!類の群の中から
選ばれる少なくとも一つ以上と、バチルス属の産生ずる
酵素と、界面活性剤とを含むことを特徴とするコンタク
トレンズ洗浄液によって達成される。
このコンタクトレンズ洗浄液において、界面活性剤は非
イオン系の界面活性剤と陰イオン系の界面活性剤である
ものが好ましく、又、単糖類及び二糖類の群の中から選
ばれる11100部に対して、バチルス属の産生ずる酵
素は1〜40部、より望ましくは3〜30部であり、界
面活性剤は0゜01〜80部、より望ましくは5〜80
部であるものが好ましく、すなわち本発明におけるコン
タクトレンズ洗浄液中における単糖類及び二w!類の群
の中から選ばれるIIは約25〜90重量%、よりより
望ましくは約50〜80重量%、バチルス属の産生ずる
酵素は約1〜10重量%、よりより望ましくは約3〜7
重量%、界面活性剤は約0゜01〜20重量%、よりよ
り望ましくは約5〜20重量%のものであることが好ま
しい。
尚、単糖類としてはぶどう糖、マンノース、ラムノース
、ガラクトース、フルクトース、アラビノース、キシロ
ース、リポース等があり、又、二糖類としては蔗糖、ト
レハロース、マルトース、ラクトース、セロビオース等
がある。
又、バチルス(Bcillus)属の産生ずる酵素とし
ては、サブチリシン、サーモリシン、スフエリカーゼ、
アミノベブチターゼ等がある。
界面活性剤としては、ポリオキシエチレンアルキルフェ
ニルエーテル硫酸エステルナトリウム、ポリオキシエチ
レンアルキル硫酸ナトリウム等の陰イオン系の界面活性
剤やポリオキシエチレンアルキルエーテル、ポリオキシ
エチレンアルキルフェニルエーテル、ポリオキシエチレ
ンーポリオキシプロピレンブロソクボリマー等の非イオ
ン系の界面活性剤がある。尚、これら陰イオン系の界面
活性剤と非イオン系の界面活性剤とを各々独立して添加
したものでも良いが、これら両者を含有させておく方が
好ましい、又、陰イオン系の界面活性剤の含を量は非イ
オン系の界面活性剤の含有量の約1/2以上であること
が好ましい。A first object of the present invention is to provide a contact lens with excellent wearability. A second object of the present invention is to provide a means for easily maintaining the wearability of contact lenses. A third object of the present invention is to provide a means for easily maintaining the wearability of a contact lens without damaging the contact lens. The object of the present invention is to obtain monosaccharides and di-I! This is achieved by a contact lens cleaning solution characterized by containing at least one selected from the group of genus Bacillus, an enzyme produced by Bacillus, and a surfactant. In this contact lens cleaning solution, the surfactant is preferably a nonionic surfactant or an anionic surfactant, and is selected from the group of monosaccharides and disaccharides based on 11,100 parts. The amount of the enzyme produced by Bacillus is 1 to 40 parts, more preferably 3 to 30 parts, and the surfactant is 0.01 to 80 parts, more preferably 5 to 80 parts.
Monosaccharides and diw! in the contact lens cleaning solution of the present invention are preferred. II selected from the group of genus Bacillus is about 25 to 90% by weight, more preferably about 50 to 80% by weight, and the enzyme produced by Bacillus is about 1 to 10% by weight, more preferably about 3 to 7% by weight.
Preferably, the surfactant is from about 0.01 to 20% by weight, more preferably from about 5 to 20% by weight. Examples of monosaccharides include glucose, mannose, rhamnose, galactose, fructose, arabinose, xylose, and lipose, and examples of disaccharides include sucrose, trehalose, maltose, lactose, and cellobiose. In addition, enzymes produced by Bacillus include subtilisin, thermolysin, sphaericase,
There are aminobebutitase, etc. Examples of surfactants include anionic surfactants such as polyoxyethylene alkyl phenyl ether sodium sulfate, polyoxyethylene alkyl sodium sulfate, polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene There are nonionic surfactants such as oxypropylene chloride polymer. Although these anionic surfactants and nonionic surfactants may be added independently, it is preferable to include both of them. The content of the agent is preferably about 1/2 or more of the content of the nonionic surfactant.
【実施例1】
ぶどう糖 30重量%ソルビトール
20重量%非イオン系界面活性剤(ポリオ
キシエチレンアルキルエーテル) 2重蓋%
陰イオン系界面活性剤(ポリオキシエチレンアルキル硫
酸ナトリウム) 1重量%サブチリシン(2,5
Au/g) 3. 5重量%塩化ナトリウム
1重量%上記の組成のものを精製水に溶かし、
酸素透過性コンタクトレンズの洗浄液を作製した。[Example 1] Glucose 30% by weight sorbitol
20% by weight nonionic surfactant (polyoxyethylene alkyl ether) double lid%
Anionic surfactant (sodium polyoxyethylene alkyl sulfate) 1% by weight subtilisin (2,5
Au/g) 3. 5% by weight sodium chloride
Dissolve 1% by weight of the above composition in purified water,
A cleaning solution for oxygen permeable contact lenses was prepared.
【実施例2】
ぶどう糖 50重量%非イオン系界面
活性荊(ポリオキシエチレンアルキルエーテル)
2重量%陰イオン系界面活性剤(ポリオキシエチ
レンアルキルフェニルエーテル硫酸エステルナトリウム
) 1重量%サブチリシン(2
,5au/g) 3. 5重蓋%塩化ナトリウム
1重量%ホウ砂 0
.3重量%上記の組成のものを精製水に溶かし、酸素透
過性コンタクトレンズの洗浄液を作製した。[Example 2] Glucose 50% by weight nonionic surfactant (polyoxyethylene alkyl ether)
2% by weight anionic surfactant (sodium polyoxyethylene alkylphenyl ether sulfate) 1% by weight subtilisin (2% by weight)
,5au/g) 3. 5-layer lid % sodium chloride
1% by weight borax 0
.. A cleaning solution for oxygen permeable contact lenses was prepared by dissolving 3% by weight of the above composition in purified water.
【比較例1】
非イオン系界面活性剤(ポリオキシエチレンアルキルエ
ーテル) 2重量%陰イオン系界面活性剤
(ポリオキシエチレンアルキル硫酸ナトリウム)
1重量%サブチリシン(2,5Au/g) 3.
5重量%塩化ナトリウム 1重量%上記
の組成のものを用い、実施例1と同様にしてコンタクト
レンズ洗浄液を作製した。[Comparative Example 1] Nonionic surfactant (polyoxyethylene alkyl ether) 2% by weight anionic surfactant (sodium polyoxyethylene alkyl sulfate)
1% by weight subtilisin (2,5 Au/g) 3.
5% by weight Sodium chloride 1% by weight A contact lens cleaning solution was prepared in the same manner as in Example 1 using the above composition.
【比較例2】
ぶどう@ 30重量%ソルビトール
20重量%非イオン系界面活性剤(ポリ
オキシエチレンアルキルエーテル) 2重量
%陰イオン系界面活性剤(ポリオキシエチレンアルキル
フェニルエーテル硫酸エステルナトリウム)
1重量%塩化ナトリウム
1重量%上記の組成のものを用い、実施例1と同様にし
てコンタクトレンズ洗浄液を作製した。[Comparative Example 2] Grape @ 30% by weight sorbitol 20% by weight nonionic surfactant (polyoxyethylene alkyl ether) 2% by weight anionic surfactant (sodium polyoxyethylene alkylphenyl ether sulfate)
1% by weight sodium chloride
A contact lens cleaning solution was prepared in the same manner as in Example 1 using the above composition of 1% by weight.
上記各側のコンタクトレンズ洗浄液を市販のオーツーフ
レノノユEX保存液中に数滴滴下して希釈したものを用
いてタンパク譬や眼脂などの汚れが付着したコンタクト
レンズを洗浄処理し、コンタクトレンズの汚れ除去の程
度を調べたので、その結果を表に示す。
尚、実施例1.2及び比較例1.2のコンタクトレンズ
洗浄液は、コンタクトレンズ洗浄液が通常何日も保存さ
れるものであるから、作製10日経過してからのもので
ある。A few drops of the above-mentioned contact lens cleaning solution on each side are added into a commercially available O2 Freno Noyu EX storage solution to dilute it and used to clean contact lenses with stains such as proteins and eye oil. The degree of stain removal was investigated and the results are shown in the table. The contact lens cleaning solutions of Example 1.2 and Comparative Example 1.2 were prepared after 10 days since contact lens cleaning solutions are usually stored for many days.
Claims (3)
も一つ以上と、バチルス属の産生する酵素と、界面活性
剤とを含むことを特徴とするコンタクトレンズ洗浄液。(1) A contact lens cleaning solution comprising at least one selected from the group of monosaccharides and disaccharides, an enzyme produced by Bacillus, and a surfactant.
浄液において、界面活性剤が非イオン系の界面活性剤と
陰イオン系の界面活性剤であるもの。(2) The contact lens cleaning solution according to claim 1, wherein the surfactant is a nonionic surfactant and an anionic surfactant.
浄液において、単糖類及び二糖類の群の中から選ばれる
糖類100部に対して、バチルス属の産生する酵素が1
〜40部であり、界面活性剤が0.01〜80部である
もの。(3) In the contact lens cleaning solution according to claim 1, 1 part of the enzyme produced by the genus Bacillus is added to 100 parts of saccharide selected from the group of monosaccharides and disaccharides.
~40 parts, and the surfactant is 0.01 to 80 parts.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2285971A JP3059752B2 (en) | 1990-10-25 | 1990-10-25 | Contact lens cleaning solution |
KR1019910018255A KR920007641A (en) | 1990-10-25 | 1991-10-17 | Contact Lens Solution |
EP19910117825 EP0482525A3 (en) | 1990-10-25 | 1991-10-18 | Contact lenses cleaning and preserving solution |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2285971A JP3059752B2 (en) | 1990-10-25 | 1990-10-25 | Contact lens cleaning solution |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH04161920A true JPH04161920A (en) | 1992-06-05 |
JP3059752B2 JP3059752B2 (en) | 2000-07-04 |
Family
ID=17698341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2285971A Expired - Fee Related JP3059752B2 (en) | 1990-10-25 | 1990-10-25 | Contact lens cleaning solution |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP3059752B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009113161A1 (en) * | 2008-03-12 | 2009-09-17 | 株式会社メニコン | Solution composition for contact lenses |
-
1990
- 1990-10-25 JP JP2285971A patent/JP3059752B2/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009113161A1 (en) * | 2008-03-12 | 2009-09-17 | 株式会社メニコン | Solution composition for contact lenses |
JP4519949B2 (en) * | 2008-03-12 | 2010-08-04 | 株式会社メニコン | Contact lens solution composition |
JPWO2009113161A1 (en) * | 2008-03-12 | 2011-07-21 | 株式会社メニコン | Contact lens solution composition |
Also Published As
Publication number | Publication date |
---|---|
JP3059752B2 (en) | 2000-07-04 |
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