JPH0385160A - Poultice with adhesive tape and its preparation - Google Patents

Abstract

PURPOSE:To obtain a poultic with an adhesive tape generating no shift by providing the poultic wherein plaster is spread and applied to the upper surface of a support, the adhesive tape holding the poultice to an adhesive surface so that the adhesive peripheral edge thereof protrudes along the outer periphery of the poultice and a release liner covering the surface of the plaster of the poultice and the adhesive peripheral edge of the adhesive tape. CONSTITUTION:A poultice with an adhesive tape is equipped with the adhesive tape 24 holding a poultice 23 on an adhesive surface 34 so that the adhesive peripheral surface of said tape protrudes along the outer periphery of the poultice 23 laminated and formed on a support 21 by spreading and applying plaster 22 to one surface of said support and the release liner 25 covering the plaster 22 of the poultice 23 and the adhesive surface 34 of the adhesive peripheral edge of the adhesive tape 24. The width of the adhesive peripheral edge provided so as to protrude along the outer periphery of the poultice 23 is pref. 5-10mm. That is, when the width is 5mm or less the poultice becomes impossible to withstand the lowering of adhesive strength accompanied by the extension and contraction of the affected part and, when the width is 10mm or more, it is necessary to widely take the area of the adhesive tape to cause an increase in cost. The adhesive tape 24 has function allowing the plaster 22 and the support 21 to fit to the skin and preventing the protrusion of a medicine from the circumference.

Description

[Detailed Description of the Invention] [Industrial Field of Application] The present invention relates to a poultice that is used by being attached to the skin of an affected area, and in particular, it prevents the poultice from slipping or slipping when used as an adhesive.
The present invention relates to a poultice with an adhesive tape provided around the poultice with an adhesive tape to prevent it from falling off, and a method for producing the same.

[Prior art] Poultices that are used by being attached to the skin of the affected area are made by attaching an adhesive tape over the poultice to prevent the poultice from slipping or falling off during application. I was using it.

For this reason, some products sell adhesive tapes that match the size and shape of the poultice individually, or are sold as an appendix to the poultice.

However, it is troublesome to apply the adhesive tape after applying the poultice, and there have been many failures such as the adhesive tape slipping off the poultice. For this reason, there has been a strong desire for a poultice with an adhesive tape that already holds the poultice in the center of the adhesive tape when it is manufactured.

However, it is difficult to continuously produce a poultice with an adhesive tape in which the poultice is already held in the center of the adhesive tape at the time of product production, and therefore it has not yet been realized.

That is, the following two methods of continuous production of adhesive tape-attached poultices have been conventionally considered.

FIG. 4 is a process diagram showing the process of continuous production of a conventional poultice with adhesive tape. As shown in Figure C, the release paper 6 of the band-shaped adhesive tape 4 which also serves as a support is peeled off and continuously supplied, and the gel-like paste 2 is extruded to form the continuously supplied adhesive tape. 4 at a predetermined position and at a predetermined interval. Furthermore, after the entire surface of the band-shaped adhesive tape 4 on which the plaster 2 is placed is continuously coated with a release liner 5, small portions are cut with a cutter 7 to obtain a poultice product 8 with adhesive tape.

In this case, it is difficult to handle the gel-like paste 2, that is, to mold the paste 2 and to place it in a predetermined location, so it is difficult to mechanize, and even if mechanized, there are many manufacturing errors. predicted, but has not yet reached continuous production.

Moreover, FIG. 5 is a process diagram showing another continuous production process of a poultice with adhesive tape. As shown in the figure, the support 11
After the paste 12 is spread and applied, the laminate is cut to obtain a poultice 13. After peeling off the release paper 16 and pasting this poultice 13 onto a continuously supplied band-shaped adhesive tape 14 at predetermined intervals, and further pasting the release liner 15 on top of it, the patch is cut into small pieces by cutting m17. Cut to obtain a poultice product 18 with adhesive tape.

In this case, it is difficult to accurately paste the poultice 13 at a predetermined position and at a predetermined interval on the band-shaped adhesive tape 14, and furthermore, the plaster 12 of the poultice 13 prepared in advance may be exposed (on the surface of the adhesive tape 14). Since it has to be attached, it is difficult to mechanize, and various problems are expected such as dirt and other substances getting into the paste 12 before the release liner 15 is attached, or the active ingredient evaporating and not being able to be used as a product. However, continuous production has not yet been achieved.

[Problem to be Solved by the Invention 1] As mentioned above, a patch with an adhesive tape that already holds a poultice in the center of the adhesive tape at the time of product production has been highly desired, but it is difficult to obtain a poultice with an adhesive tape. Regarding the manufacturing method, since the paste of the poultice is in the form of a gel, it is difficult to handle, and there are problems such as contamination with dust and evaporation of the active ingredient before the release liner is attached. In addition, it is difficult to apply the adhesive tape accurately to the adhesive surface, and it is difficult to establish a continuous production process or to use a machine to accurately shape and place the gel-like paste. It is necessary to create a new machine, such as a machine that allows the machine to be placed in the same position, and continuous production has not yet been achieved.

The present invention provides a poultice with an adhesive tape provided around the poultice to prevent it from slipping or falling off when used, and it does not require the development of a special machine, and can be manufactured using conventional methods. The purpose is to obtain a manufacturing method that allows easy manufacturing using a machine.

[Means for Solving the Problems] The poultice with adhesive tape according to the first invention includes a poultice in which a paste is spread and applied on the upper surface of a support, and an adhesive periphery extending along the outer periphery of the poultice. C: An adhesive tape that holds the poultice on its adhesive surface; and a release liner that covers the plaster surface of the poultice and the adhesive surface of the adhesive periphery of the adhesive tape.

In the method for manufacturing a poultice with adhesive tape according to the second invention, a plaster is spread and applied on the support surface, and the paste is applied to the plaster surface side! L1
a step of bonding the m-liner; punching out the laminate of the support and paste into a predetermined punched shape leaving the release liner, and removing the excess support and paste other than the punched shape with the release liner; a step of removing it from above; a step of pasting an adhesive tape on the entire surface of the release liner leaving the laminate of the cut-out shaped plaster and support on the surface, and then cutting into small pieces; It is something.

[Function] In the first invention, there is provided a poultice prepared by spreading and coating a C paste on the upper surface of a support, and an adhesive having the poultice held on the adhesive surface so that the adhesive periphery extends along the outer periphery of the poultice. Since the tape includes a release liner that covers the plaster surface of the poultice and the adhesive surface of the adhesive periphery of the adhesive tape, after the poultice is applied (and the adhesive tape is further applied on top of the adhesive tape). This eliminates the hassle of pasting the plaster and prevents the paste from protruding when pasting.

In the second invention, the paste is spread on the support surface,
A step of attaching a release liner to the side of the plaster: Punching the laminate of the support and plaster into a predetermined punched shape, leaving the release liner, and removing the excess support and plaster other than the punched shape. removing the body from above the release liner; pasting adhesive tape on the entire surface of the release liner leaving the laminate of the cut-out shaped plaster and support on the surface, and then cutting into small pieces; Steps: Since the paste is spread and coated on the support and the release liner is immediately attached to the surface of the paste, contamination with dust and the like and evaporation of the active ingredient are reduced. In addition, since the laminate of the support and plaster is punched out leaving the release liner, and the excess laminate is removed from above the release liner, the shape of the punch is free, and the release liner remains connected. Continuous manufacturing becomes easy. In addition, when applying adhesive tape to the entire surface of the release liner, the adhesive tape only needs to be adjusted to cover the release liner, making positioning easier and continuous production easier. can be manufactured.

[Example] FIG. 1 is a sectional view showing the structure of a poultice with adhesive tape according to the present invention, and FIG. 2 is an enlarged sectional view of FIG. There is a poultice 23 formed by spreading and applying the body 22 to form a laminate. The adhesive tape 24 holds the poultice 23 on the adhesive surface 34 so that the adhesive periphery protrudes along the outer circumference C of the poultice 23, the paste 22 of the poultice 23, and the adhesive surface of the adhesive periphery of the adhesive tape 24. 34 and a release liner 25 coated with an adhesive tape.

The width of the adhesive periphery provided so as to extend along the outer periphery of the poultice 23 is preferably 5 to 10 mm, that is, 51111
If it is less than 10m5, it will not be possible to cope with the decrease in adhesive strength due to expansion and contraction of the affected area.If it is more than 10m5, there will be no decrease in adhesive strength, but the area of the adhesive tape will need to be widened, which will increase the cost. This is to become.

In addition, the paste 22 of the poultice with adhesive tape according to the present invention contains a drug that has a direct effect on the skin and a drug that has an effect on the local or whole body through transdermal absorption in a base such as a shape-retaining agent or adhesive. This is what I did.

A specific example of the effective drug contained in this paste 22 is indomethacin as an analgesic and anti-inflammatory agent.

These include ketoprofen, flurbiprofen, ibuprofen, piroxicam, methyl salicylate, glycol salicylate, °C-menthol, dl-camphor, nonylic acid varynylyl acid, kabsaicin, and various herbal medicines. Coronary vasodilators include nitroglycerin, nifedipine, isosorbite nitrate, and the like. Other drugs include clonidine and kallikrein (antihypertensive drugs).

These include corticosteroids and antibacterial agents.

In addition, examples of the shape-retaining/adhesive agent contained in the plaster 22 include:
Sodium carboxymethylcellulose, sodium methylcellulose, polyvinyl alcohol, sodium alginate, sodium polyacrylate, polyvinylpyrrolidone, gelatin, binder such as carbobol, natural rubber 1 synthetic rubber, styrene-isobrene-styrene block copolymer, silicone resin There are adhesives based on polyvinyl ether and polyvinyl ether.

Further, as a humectant to be used as necessary, there are glycerin, propylene glycol, sorbitol, and the like.

Further, support 2 of poultice with adhesive tape according to the present invention
1 is a material that serves to apply and hold the paste, and has good elasticity, breathability, and texture to adhere closely to the drug, prevent the drug from leaking, and improve the fit to the skin. is used.

Specific examples include flannel, woven fabric, and stockinette.

There are nonwoven fabrics, plastic films, etc. Note that since the manufacturing method according to the present invention includes a punching step, it is possible to freely create shapes such as rounded corners and slits.

Further, the adhesive tape 24 of the poultice with adhesive tape according to the present invention has a paste and a support attached to the entire circumference in order to better fit the skin. This has the following characteristics. That is, (1) the plaster 22 adheres closely to the skin and does not peel off. (2) Prevent the drug from protruding from the surrounding area. Therefore, it is possible to obtain a poultice with adhesive tape that does not cause the plaster 22 to stick to underwear or come off. As a specific material for the adhesive tape 24, a material with high air permeability such as a nonwoven fabric or a plastic film is used, and it can also have a structure with small ventilation holes or a large ventilation hole in the center.

Specific examples of the adhesive used in the adhesive tape 24 include polyacrylic ester, natural/synthetic rubber, and styrene-isoprene-styrene block polymers, which cause less irritation to the skin. be done.

Figures 3A and 3B are process diagrams showing an example of the manufacturing process of a poultice with adhesive tape.

As shown in FIG. 3a, the plaster 22 is spread and coated on a band-shaped support 21, and a release liner 25 is laminated on the surface of the plaster 22 to form a band-shaped poultice 33. As mentioned above,
Since the release liner 25 was attached to the surface of the plaster 22 immediately after the plaster 22 was spread and coated on two supports, there was little chance of contamination with dust or the like and evaporation of the active ingredient.

As shown in FIG. 3b, the strip-shaped poultice 33 is turned upside down, and the release liner 25. Plaster 22° Support 2
Set to 1. The support 21 and the paste 22 are punched out at regular intervals from the band-shaped poultice 33 by a lithographic punching machine 29 having a rectangular cutting die, leaving the release liner 25. Separate portion 30. Further, the excess portion 30 between the support and the plaster at the outer peripheral portion of the punched poultice 23 is removed from the release liner 25.

The obtained poultice 23 is strip-shaped! ! They are placed on the 1 m liner 25 at positions having edges of equal length in both width directions, and at intervals of twice the edge.

In order to remove the excess portion 30 from above the release liner 25, when punching out the release liner 25 while leaving it, the shape of the punch can be freely selected; The width of the adhesive edge is 5 to 10
Since the mra is good, it is approximately rectangular and leaves an edge of 5 to 10+ seconds.

As shown in FIG. 3c, the punched paste 22 and the support 21
A band-shaped adhesive tape 24 from which the release paper 26 has been removed is pasted onto the entire surface of the release liner 25 with the poultice 23 remaining on the surface. After pasting, apply poultice 23 using cutting machine 27.
Since the adhesive tape 24 is pasted on the entire surface of the release liner 25 as described in 0 or above where the product z8 was obtained by cutting the space into small pieces, the adhesive tape 24 may be prepared so as to cover the release liner 25. Easy positioning and continuous manufacturing.

In addition, in FIGS. 3a and 3b, the terminal end may continue to the next step or may be wound up on a drum or the like.

Furthermore, the punching machine 29 and the cutting machine 27 are not limited to those in the embodiment. For example, a die-roll cut type punching machine may be used instead of the lithographic punching machine, and the cutting machine may also be a die-roll cutting machine. You may also use a cutting machine.

As mentioned above, with this manufacturing method, the extra punched parts have to be discarded, which increases costs, but compared to conventional continuous manufacturing, there are extremely few manufacturing errors.
It is a manufacturing method that is fully profitable.

[Effects of the Invention] As explained above, in the first aspect of the present invention, there is provided a poultice in which a paste is spread and applied on the upper surface of a support, and a poultice with an adhesive periphery extending along the outer periphery of the poultice. It is equipped with an adhesive tape that holds a poultice on its adhesive surface, and a release liner that covers the plaster surface of the poultice and the adhesive surface of the adhesive periphery of the adhesive tape, so that the poultice can be attached. This eliminates the trouble of applying an adhesive tape on top of the adhesive tape after applying the adhesive tape, and no adhesive tape comes out during application.

In the second invention, the paste is spread and applied on the support surface,
a step of pasting a release liner on the side of the plaster; punching out the laminate of the support and plaster into a predetermined punched shape, leaving the release liner; and removing excess support and plaster other than the punched shape; Step of removing the body from above the release liner: Applying adhesive tape to the entire surface of the release liner leaving the laminate of the cut-out shaped plaster and support on the surface, and then cutting into small pieces. Process: Since it has the following steps, spread the plaster on the support and immediately apply it on the plaster surface! ! Since the IJ1f liner is attached, there is less contamination by dust and evaporation of active ingredients. In addition, since the laminate of the support and plaster is punched out leaving the release liner, and the excess laminate is removed from above the release liner, the shape of the punch is free, and the release liner remains connected. Continuous manufacturing becomes easy. In addition, when attaching adhesive tape to the entire surface of the release liner, the adhesive tape only needs to be adjusted to cover the release liner, making positioning easier and continuous production easier. It has the advantage of being able to be manufactured in a number of ways.

[Brief explanation of drawings]

FIG. 1 is a sectional view showing the structure of a poultice with adhesive tape according to the present invention, FIG. 2 is an enlarged sectional view of FIG. 1, and FIG.
a % 0 Figure is a process diagram showing an example of the manufacturing process of a poultice with an adhesive tape, Figure 4 is a process diagram showing a conventional continuous manufacturing process of a poultice with an adhesive tape, and Figure 5 is a process diagram of a conventional process for producing a poultice with an adhesive tape. It is a process diagram showing the process of continuous production of a poultice with an adhesive tape.

Claims (2)

[Claims] (1) A poultice prepared by spreading a plaster on the upper surface of a support; an adhesive tape holding the poultice on its adhesive surface so that the adhesive periphery extends along the outer periphery of the poultice; and the poultice. 1. A poultice with an adhesive tape, comprising a release liner that covers the plaster surface and the adhesive surface of the adhesive periphery of the adhesive tape. (2) A step of spreading and coating the paste on the support surface and pasting a release liner on the paste surface; and cutting the laminate of the support and the paste in a predetermined manner, leaving the release liner behind. a step of punching into a shape and removing excess support and paste other than the punched shape from the release liner; A method for producing a poultice with an adhesive tape, comprising the steps of: pasting an adhesive tape on the surface and then cutting the adhesive tape into small pieces.