JPH0374680B2 - - Google Patents

Info

Publication number
JPH0374680B2
JPH0374680B2 JP61299062A JP29906286A JPH0374680B2 JP H0374680 B2 JPH0374680 B2 JP H0374680B2 JP 61299062 A JP61299062 A JP 61299062A JP 29906286 A JP29906286 A JP 29906286A JP H0374680 B2 JPH0374680 B2 JP H0374680B2
Authority
JP
Japan
Prior art keywords
thymosin
obzl
group
compound
bzl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61299062A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62142200A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS62142200A publication Critical patent/JPS62142200A/ja
Publication of JPH0374680B2 publication Critical patent/JPH0374680B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/837—Lymph; lymph-glands; thymus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP61299062A 1981-09-18 1986-12-17 ビス−チモシンα↓１化合物、その製法及び該化合物を含有する、免疫防御細胞を刺激する薬剤 Granted JPS62142200A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3137231.7 1981-09-18
DE19813137231 DE3137231A1 (de) 1981-09-18 1981-09-18 Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen

Publications (2)

Publication Number Publication Date
JPS62142200A JPS62142200A (ja) 1987-06-25
JPH0374680B2 true JPH0374680B2 (OSRAM) 1991-11-27

Family

ID=6142082

Family Applications (2)

Application Number Title Priority Date Filing Date
JP57159688A Granted JPS5869854A (ja) 1981-09-18 1982-09-16 スクシニル−ビスデスアセチル−チモシンα↓１、その製法及び該化合物を含有する、免疫防御細胞を刺激する薬剤
JP61299062A Granted JPS62142200A (ja) 1981-09-18 1986-12-17 ビス−チモシンα↓１化合物、その製法及び該化合物を含有する、免疫防御細胞を刺激する薬剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP57159688A Granted JPS5869854A (ja) 1981-09-18 1982-09-16 スクシニル−ビスデスアセチル−チモシンα↓１、その製法及び該化合物を含有する、免疫防御細胞を刺激する薬剤

Country Status (8)

Country Link
US (1) US4396605A (OSRAM)
EP (1) EP0075776B1 (OSRAM)
JP (2) JPS5869854A (OSRAM)
AT (1) ATE10189T1 (OSRAM)
AU (1) AU531708B2 (OSRAM)
CA (1) CA1246547A (OSRAM)
DE (2) DE3137231A1 (OSRAM)
DK (1) DK166391C (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3137231A1 (de) * 1981-09-18 1983-04-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen
US4504415A (en) * 1983-04-04 1985-03-12 Hoffman-La Roche Inc. Synthesis of thymosin α1 and desacetyl thymosin α1
DE3633651A1 (de) * 1986-10-03 1988-04-14 Alfred Dr Dick Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis
US5728680A (en) 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
US5807830A (en) * 1987-12-30 1998-09-15 Cytoven J.V. Method for treatment of purulent inflammatory diseases
US5811399A (en) * 1988-12-14 1998-09-22 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US6100380A (en) * 1991-10-28 2000-08-08 Cytran, Inc. Immunomodulating peptides and methods of use
US6066622A (en) 1991-10-28 2000-05-23 Cytran, Inc. Immunomodulating peptides and methods of use
IT1256925B (it) * 1992-08-05 1995-12-27 Impiego di frammenti o/e di derivati della timosina alfa 1.
CN1058500C (zh) * 1993-02-03 2000-11-15 施塞克龙药品公司 胸腺素α－1衍生物
AU6359594A (en) * 1993-03-04 1994-09-26 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633258A5 (en) * 1976-10-28 1982-11-30 Hoffmann La Roche Process for preparing thymosin alpha 1
DE2919592A1 (de) * 1979-05-15 1981-01-15 Max Planck Gesellschaft Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
EP0033384B1 (de) * 1980-01-18 1984-02-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente
DE3137231A1 (de) * 1981-09-18 1983-04-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen

Also Published As

Publication number Publication date
JPS6244000B2 (OSRAM) 1987-09-17
JPS5869854A (ja) 1983-04-26
JPS62142200A (ja) 1987-06-25
DK166391B (da) 1993-05-10
AU8847382A (en) 1983-05-12
CA1246547A (en) 1988-12-13
EP0075776B1 (de) 1984-11-07
US4396605A (en) 1983-08-02
DE3261206D1 (en) 1984-12-13
AU531708B2 (en) 1983-09-01
DE3137231A1 (de) 1983-04-14
ATE10189T1 (de) 1984-11-15
EP0075776A1 (de) 1983-04-06
DK414182A (da) 1983-03-19
DK166391C (da) 1993-09-27

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