JPH03505224A - 眼の瞳孔の収縮をそれぞれ誘起または防止するための方法および手段 - Google Patents

眼の瞳孔の収縮をそれぞれ誘起または防止するための方法および手段

Info

Publication number
JPH03505224A
JPH03505224A JP2506058A JP50605890A JPH03505224A JP H03505224 A JPH03505224 A JP H03505224A JP 2506058 A JP2506058 A JP 2506058A JP 50605890 A JP50605890 A JP 50605890A JP H03505224 A JPH03505224 A JP H03505224A
Authority
JP
Japan
Prior art keywords
cck
eye
cholecystokinin
antagonists
terminal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2506058A
Other languages
English (en)
Japanese (ja)
Inventor
ビル，アンデルス
Original Assignee
カビ・フアーマシア・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カビ・フアーマシア・アクチエボラーグ filed Critical カビ・フアーマシア・アクチエボラーグ
Publication of JPH03505224A publication Critical patent/JPH03505224A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2207—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2506058A 1989-04-03 1990-04-03 眼の瞳孔の収縮をそれぞれ誘起または防止するための方法および手段 Pending JPH03505224A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8901149A SE8901149D0 (sv) 1989-04-03 1989-04-03 Medel foer inducering respektive foerhindrande av pupillkonstriktion i oegat
SE8901149-8 1989-04-03

Publications (1)

Publication Number Publication Date
JPH03505224A true JPH03505224A (ja) 1991-11-14

Family

ID=20375526

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2506058A Pending JPH03505224A (ja) 1989-04-03 1990-04-03 眼の瞳孔の収縮をそれぞれ誘起または防止するための方法および手段

Country Status (10)

Country Link
EP (1) EP0422181A1 (bg)
JP (1) JPH03505224A (bg)
KR (1) KR920700044A (bg)
AU (1) AU627570B2 (bg)
BG (1) BG93398A (bg)
CA (1) CA2030525A1 (bg)
FI (1) FI905952A0 (bg)
HU (1) HU206185B (bg)
SE (1) SE8901149D0 (bg)
WO (1) WO1990011773A1 (bg)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206237A (en) * 1991-05-14 1993-04-27 Merck & Co., Inc. Benzodiazepine analogs
US5185331A (en) * 1991-05-14 1993-02-09 Merck & Co., Inc. Triazolobenzodiazepines
US5210082A (en) * 1991-05-16 1993-05-11 Merck & Co., Inc. 2-benzazepines with 5- and 6-membered heterocyclic rings to treat pain and anxiety disorders
US5189050A (en) * 1991-06-03 1993-02-23 Merck & Co., Inc. Fermentation analogs of virginiamycin m1 to treat panic and anxiety disorder
US5177071A (en) * 1991-06-17 1993-01-05 Merck & Co., Inc. 1,4-benzodiazepines with 6-membered heterocyclic rings to treat panic and anxiety disorder
SE9201425D0 (sv) * 1992-05-06 1992-05-06 Kabi Pharmacia Ab Method and means for preventing constriction of the pupil in the eye

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400377A (en) * 1980-09-26 1983-08-23 Farmitalia Carlo Erba, S.P.A. Use of polypeptides as analgesic drugs
DK489683A (da) * 1982-10-27 1984-04-28 Amano Pharma Co Ltd Fremgangsmaade til fremstilling af peptider
IT1179866B (it) * 1984-12-12 1987-09-16 Rotta Research Lab Derivati del triptofano farmaceuticamente attivi e composizioni farmaceutiche che li contengono
IT1179894B (it) * 1984-12-27 1987-09-16 Rotta Research Lab Proglumide e composizioni farmaceutiche che la contengono per l impiego nella terapia di affezioni neoplastiche
IT1204430B (it) * 1986-01-10 1989-03-01 Alfio Bertolini Composizioni farmaceutiche comprendenti peptidi del gruppo colecistochinina-cerulina per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria
DD272653A1 (de) * 1987-02-09 1989-10-18 Akad Wissenschaften Ddr Verfahren zur herstellung neuer antagonisten des cholecystokinins

Also Published As

Publication number Publication date
AU627570B2 (en) 1992-08-27
HUT55994A (en) 1991-07-29
FI905952A0 (fi) 1990-12-03
WO1990011773A1 (en) 1990-10-18
KR920700044A (ko) 1992-02-19
SE8901149D0 (sv) 1989-04-03
HU903583D0 (en) 1991-05-28
CA2030525A1 (en) 1990-10-04
HU206185B (en) 1992-09-28
EP0422181A1 (en) 1991-04-17
AU5428290A (en) 1990-11-05
BG93398A (bg) 1993-12-24

Similar Documents

Publication Publication Date Title
MooreLori et al. Discovery and preclinical development of netarsudil, a novel ocular hypotensive agent for the treatment of glaucoma
Rehman et al. Diminished neurogenic but not pharmacological erections in the 2-to 3-month experimentally diabetic F-344 rat
US6489350B1 (en) Methods for treating neuropathic pain using heteroarylmethanesulfonamides
EP2099468B1 (en) Methods of use of trk receptor modulators
UNGER et al. Calcitonin gene-related polypeptide as a mediator of the neurogenic ocular injury response
US9789117B2 (en) Use of sigma ligands in diabetes type-2 associated pain
Camras et al. The pathophysiological effects of nitrogen mustard on the rabbit eye. II. The inhibition of the initial hypertensive phase by capsaicin and the apparent role of substance P.
Crooke et al. Update in glaucoma medicinal chemistry: emerging evidence for the importance of melatonin analogues
KR101103141B1 (ko) Ｒｈｏ 키나아제 억제제와 β 차단약으로 이루어진 녹내장치료제
Sears et al. Adrenergic modulation of the outflow of aqueous humor.
JPH03505224A (ja) 眼の瞳孔の収縮をそれぞれ誘起または防止するための方法および手段
JP2005533087A (ja) 神経損傷の処置にリアノジン拮抗剤を用いる方法
AU2017256803A1 (en) Dipeptidyl peptidase-4 inhibitors for topical eye treatment of retinal neurodegenerative diseases
Wang et al. Effect of 5-methylurapidil, an a1a-adrenergic antagonist and 5-hydroxytryptamine1a agonist, on aqueous humor dynamics in monkeys and rabbits
WO2003092693A1 (en) Methods of treatment of glaucoma and other conditions mediated by nos-2 expression via inhibition of the egfr pathway
AU2012237066B2 (en) Pharmaceutical composition for preventing or treating macular degeneration
WO1993021911A1 (en) Method and means for preventing constriction of the pupil in the eye
Gondim et al. Exogenous vasopressin influences intraocular pressure via the V1 receptors
CHU et al. 8OH-DPAT-Induced ocular hypotension: sites and mechanisms of action
EP0522596A1 (en) Method and means for inducing constriction of the pupil in the eye
RU2003331C1 (ru) Средство дл регулировани сокращени глазного зрачка
Potter et al. Lisuride acts at multiple sites to induce ocular hypotension and mydriasis
WO1999007353A1 (en) USE OF α1A-ADRENERGIC RECEPTOR ANTAGONISTS IN GLAUCOMA THERAPY
Mandahl Effects of the substance P antagonist [D-Arg1, D-Pro2, D-Trp7, 9, Leu11] SP on miosis caused by echothiophate iodide or pilocarpine hydrochloride
AU2011253937B2 (en) Methods of use of TRK receptor modulators