JPH0341011A - Controlling agent of termite - Google Patents

Abstract

PURPOSE:To obtain controlling agent of termite exhibiting excellent moth- proofing effect and high safety containing extract of neem as active ingredient. CONSTITUTION:Bark, leaf, twig, fruit and seed of neem (means as margosa, crape fern and Melia azadirachta) as evergreen trees inhabiting centering around Himalaya district in India are dried and finely cut, then extracted with organic solvent or water-containing organic solvent by an ordinary method. Carrier, dispersant, emulsifier, coating film-forming agent or wettable powder, etc., containing 0.1-80wt.%, preferably 0.3-50wt.% said neem extract is suitably mixed and prepared by the ordinary method to afford the objective substance. Shape of liquid agent, solid agent, paint, adhesive, emulsion, suspension, powder or air spray, etc., is able to be prepared and applied by a method such as dispersing, spraying, coating or plastering.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to a termite control agent containing an extract of neem as an active ingredient.

[Conventional technology]

Termites are major pests that cause severe damage to wood or wood products.2 Man-made wooden structures, such as buildings, foundations, shelf pillars, etc. To control termites, soil and/or building materials are treated with synthetic agents such as organophosphate insecticides and organochlorine insecticides.

[Problem to be solved by the invention]

Most of the termite control agents currently in use are chemically synthesized products, and their safety for humans has become an issue. Therefore, there is an increasing need for safer pest control agents.

[Means to solve the problem]

An object of the present invention is to provide a highly effective and highly safe termite control agent that is derived from a natural product rather than a synthetic product.

The present inventors conducted extensive research to select components with a high termite-controlling effect from among natural products that are safe for the human body, and as a result, they discovered that neem extract has a termite-controlling effect. Furthermore, as a result of research into the formulation and usage of neem extracts, the present invention was completed. That is, the present invention is a termite control agent characterized by containing an extract of neem in an organic solvent or a water-containing organic solvent as an active ingredient.

[Effect]

There are no particular restrictions on the termites that are the object of the present invention, and there are no particular limitations on the termites, including Coptotermes formosanus.
), Yamato termite (Reticuliterme)
s 5 peratus ), etc.

The neem of the present invention is neem or neem, Melia azadira
chta), and is an evergreen tree that is widely distributed and grown in Southeast Asia, mainly in the Himalayan region of India. In India, it is considered a sacred tree and is used as a roadside tree and a shade tree.The 0 leaves have large saw-toothed whorls, similar to melium, and produce small white flowers that emit a honey-like fragrance. In India, neem is heavily used as a bitter tonic, astringent and bicyclic fever medicine, and has been confirmed to be highly safe.

The neem extract of the present invention includes one leaf of neem bark, a twig,
One or more parts of fruits and seeds are dried and shredded, an organic solvent or combined organic solvent is added thereto, and extraction is performed by a conventional method at room temperature or under heating, and then the extraction residue is extracted. The organic solvents used for extraction, which are obtained by distilling off or concentrating the solvent from the mustard liquor, include alcohols such as methanol, ethanol, propanol, isopropanol, butanol, and octanol; propylene glycol; Polyols such as hexylene glycol and glycerin; ketones such as methyl ether, ethyl ether, propyl ether, isopropyl ether, tetrahydrofuran, and dioxane; esters such as ethyl acetate; halogenated hydrocarbons such as chloroform and dichloromethane; hexane, isooctane, kerosene, paraffin, henzene, toluene,
Any of hydrocarbons such as xylene and hydrated products thereof may be used, but especially alcohols such as methanol and ethanol, ethers such as methyl ether and ethyl ether, halogenated hydrocarbons such as dichloromethane, and hydrated products thereof. are suitable for the purposes of the present invention.

Depending on the solvent used, the extract can be obtained in the form of oil, extract, absolute, genius gin, syrup, essence, tincture, etc., and any form can be used as a termite control agent. The neem extract may also be formulated into a dosage form suitable for the application area and application method, such as a liquid dosage form or a solid dosage form, using a suitable carrier.

The preparation of the liquid preparation takes into account the carrier used depending on the extracted solvent,
Just select an appropriate solvent, such as water; ethanol,
Alcohols such as isopropanol; Ketones such as acetone and methyl ethyl ketone; Ethers such as tetrahydrofuran and dioxane; Hydrocarbons such as hexane, kerosene, petroleum benzine, and toluene; Esters such as ethyl acetate; Halogenated hydrocarbons such as dichloromethane The following examples can be given. Alternatively, the extract may be directly dissolved or dispersed in an emulsifier. Furthermore, by blending commonly used additives such as film forming agents, emulsifiers, dispersants, spreading agents, wetting agents, stabilizers, and propellants, we can create coatings, adhesives, emulsions, irrigation agents, suspensions, etc. It can be used in any desired form such as a preparation, lotion, cream, or aerosol.

Examples of carriers used in the preparation of solid preparations include silicic acid, kaolin, activated carbon, bentonite, diatomaceous earth, talc,
Examples include mineral powders such as clay, calcium carbonate, and ceramic powder; vegetable powders such as wood flour, soybean flour, wheat flour, and powder; and clathrate compounds such as cyclodextrin; powders, air sprays, etc. It is used in the form of Furthermore, known repellents, insecticides, potency enhancers, antioxidants, bactericides, fungicidal agents, colorants, etc. can be added to the termite control agent of the present invention.

When using the termite control agent of the present invention, it can be applied to termite-infested areas where a control effect is required, such as subfloor kitchens, bathrooms, walls, etc., by methods such as spraying, spraying, coating, and pasting. Furthermore, termites can be controlled by impregnating, spraying or applying the termite control solution of the present invention to wood, which is food for termites, and wood products including paper and paper products. Alternatively, the liquid form of the termite control agent of the present invention may be applied in advance to a suitable sheet-like base material (synthetic resin sheet, paper non-woven fabric, etc.), two drops of impregnated material may be applied, and the sheet material held by kneading may be placed on the desired location. It can be used by pasting it on.

The content of neem extract in the termite control agent of the present invention is:
It may be determined as appropriate depending on the dosage form, application method, application location, etc., and is not particularly limited, but usually dispersing emulsifiers, diluents, water utilization, etc., sheet-like base materials, furniture parts, etc.
When used in various forms such as solid preparations, the neem extract is contained in an amount of 0.1 to 80% by weight, preferably 0.3 to 50% by weight.

(Examples) The present invention will be explained in more detail below with reference to Examples and Test Examples.

Example 1 Methanol 42 was added to 500 g of dried shredded neem bark, and extraction treatment was carried out at room temperature for about 3 days. The obtained extraction mixture was filtered to obtain a methanol extract. Four additional portions of methanol were added to the extraction residue again, and the extraction treatment was carried out at room temperature for about 3 days. Repeat this operation 3 times in total and methanol extract 3
The batches were collected and concentrated to dryness using a rotary evaporator to obtain 30 g of brown powder. 6 g of an emulsifier (Himar 326 H, manufactured by Matsumoto Yushi Co., Ltd.) was added to 14 g of the obtained powder and emulsified with stirring to prepare a wettable powder.

Example 2 Two parts of ethanol was added to 200 g of dried shredded neem fruit, and the mixture was placed in a reflux tube and heated under reflux for 4 hours. The extraction mixture was filtered to obtain an ethanol extract. Add 2 fl of pharmacopoeial ethanol to the extraction residue again, repeat the same operation three times, combine the ethanol extracts and concentrate, and the reddish brown viscous liquid 2
Obtained 0g. This extract solidified when cold. Obtained extract 1
4g emulsifier (r Heimaru 326 HJ Matsumoto Yushi)
6g was added to prepare a wettable powder.

Example 3 180 g of shredded dried neem seeds and 2 dichloromethane
2 was added, and the same operation as in Example 1 was performed for extraction. The dichloromethane extract was concentrated to obtain 19 g of a reddish brown viscous liquid. Add an emulsifier ("Heimaru 326H" to 9 g of the obtained extract)
J Matsumoto Yushi Co., Ltd.) was added to prepare a wettable powder.

Example 4 Two parts of the extract of Example 2, 78 parts of xylene, and 20 parts of an emulsifier, Tsurupol (manufactured by Toho Chemical Co., Ltd.) were mixed to prepare an emulsion.

Example 5 2 f of water-containing methanol (methanol/water = 9/1 (v/v)) was added to 250 g of dried shredded neem bark, and extraction was carried out in the same manner as in Example 1.

The water-containing methanol solution was concentrated to obtain 20 g of brown powder.

Test Example 1 A solution prepared by dissolving a predetermined amount of the neem extract obtained in Example 2 in ethanol was applied to Nito paper (paper disc manufactured by Toyo P Paper Co., Ltd.) having a diameter of 8 mm and air-dried. This was placed in a plastic petri dish with a diameter of 35 mm, 10 Yamato termites were released, and the mortality rate was determined. Table 1 shows the amount of neem extract tested and the mortality rate (%).

Table 1 Test Example 2 A solution prepared by dissolving a predetermined amount of the neem extract obtained in Example 5 in methanol was applied to a pepper disk and air-dried. This was tested in the same manner as Test Example 1. Table 2 shows the amount of neem extract tested and the mortality rate (%).

Table 2 Test Example 3 Water was added to the wettable powder of Example 1 to prepare an emulsifier of neem extract. This was applied to a dried red pine wood piece (1 x 1 x 1 cm) so that a predetermined amount of neem extract was applied and dried. The treated wood pieces were placed in a cage containing wet sea sand, and 100 Japanese termites were released. After 20 days, the mortality rate and the amount of decrease in wood chip weight were determined. Table 3 shows the mortality rate and reduction in wood chip weight of the neem extract.

Table 3 Test Example 4 Water was added to the wettable powder of Example 3 to prepare a diluted solution. This was applied to a piece of dried red pine wood, and the same test as in Test Example 3 was carried out. The results are shown in Table 4.

Table 4 Test Example 5 xylene was added to the emulsion of Example 4 to prepare a diluted solution. This was applied to dried red pine wood chips, and the same test as in Test Example 3 was conducted. The results are shown in Table 5.

Table 5 [Effects of the Invention] As is clear from the above test examples, the termite control agent of the present invention exhibits an excellent insect control effect against termites, and is highly safe and very useful.

Claims (1)

[Claims] A termite control agent characterized by containing an extract of neem in an organic solvent or a water-containing organic solvent as an active ingredient.