JPH0256070B2 - - Google Patents
Info
- Publication number
- JPH0256070B2 JPH0256070B2 JP18532682A JP18532682A JPH0256070B2 JP H0256070 B2 JPH0256070 B2 JP H0256070B2 JP 18532682 A JP18532682 A JP 18532682A JP 18532682 A JP18532682 A JP 18532682A JP H0256070 B2 JPH0256070 B2 JP H0256070B2
- Authority
- JP
- Japan
- Prior art keywords
- tank
- upflow
- pipe
- culture
- closed system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 235000015097 nutrients Nutrition 0.000 claims description 35
- 230000001954 sterilising effect Effects 0.000 claims description 21
- 239000007788 liquid Substances 0.000 claims description 20
- 238000009826 distribution Methods 0.000 claims description 14
- 230000004151 fermentation Effects 0.000 claims description 10
- 238000000855 fermentation Methods 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims description 4
- 238000005273 aeration Methods 0.000 claims description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 239000007789 gas Substances 0.000 description 26
- 238000004659 sterilization and disinfection Methods 0.000 description 15
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 8
- 108010027322 single cell proteins Proteins 0.000 description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
- 229910052799 carbon Inorganic materials 0.000 description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 238000010564 aerobic fermentation Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 241000863393 Methylophilus methylotrophus Species 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000011031 large-scale manufacturing process Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 238000011045 prefiltration Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 239000002912 waste gas Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 240000001377 Pseudomonas sp. PM-2 Species 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 238000010960 commercial process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 238000001139 pH measurement Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical class C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/22—Perforated plates, discs or walls
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/24—Draft tube
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/26—Conditioning fluids entering or exiting the reaction vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8132085 | 1981-10-23 | ||
GB8132085 | 1981-10-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS58155079A JPS58155079A (ja) | 1983-09-14 |
JPH0256070B2 true JPH0256070B2 (fr) | 1990-11-29 |
Family
ID=10525371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18532682A Granted JPS58155079A (ja) | 1981-10-23 | 1982-10-21 | 醗酵槽装置 |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS58155079A (fr) |
DE (1) | DE3239210A1 (fr) |
FR (1) | FR2515206B1 (fr) |
SU (1) | SU1440352A3 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7788622B2 (en) | 2003-11-21 | 2010-08-31 | Mentor Graphics Corporation | Distributed autorouting of conductive paths |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102013111592A1 (de) * | 2013-10-21 | 2015-04-23 | Binowa Gmbh | Verfahren und Vorrichtung zur Abscheidung schwerer Bestandteile aus hochviskosem Ausgangssubstrat von Biogasanlagen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1519698A (fr) * | 1967-02-07 | 1968-04-05 | Fermentation | Perfectionnements au procédé de fermentation des moûts dans la fabrication de la bière |
FR1602670A (en) * | 1968-07-18 | 1971-01-11 | Fermentation of micro organisms using - petrochemicals | |
US3865691A (en) * | 1970-10-30 | 1975-02-11 | Standard Oil Co | Single-cell protein materials from ethanol |
GB1417487A (en) * | 1973-05-16 | 1975-12-10 | Imp Chemical Ind Lt | Liquid circulation and gas contacting device |
CH563458A5 (fr) * | 1974-03-18 | 1975-06-30 | Mueller Hans Maennedorf | |
CH572978A5 (en) * | 1974-09-10 | 1976-02-27 | Mueller Hans Maennedorf | Bioreactor cooling-aeration system - has air tubes ending in suction zone of circulating substrate heat exchanger tubes |
NZ178293A (en) * | 1974-08-14 | 1978-04-28 | Ici Ltd | Continous fermentation of a culture: in troduction of nutrient medium into fermenter |
GB2002417B (en) * | 1977-08-09 | 1982-05-26 | Ici Ltd | Gas-liquid circulating and contacting apparatus |
US4282328A (en) * | 1979-12-19 | 1981-08-04 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Apparatus for cultivating aerobic microorganisms and process for cultivation using the same |
-
1982
- 1982-10-20 FR FR8217544A patent/FR2515206B1/fr not_active Expired
- 1982-10-21 JP JP18532682A patent/JPS58155079A/ja active Granted
- 1982-10-21 SU SU823506788A patent/SU1440352A3/ru active
- 1982-10-22 DE DE19823239210 patent/DE3239210A1/de active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7788622B2 (en) | 2003-11-21 | 2010-08-31 | Mentor Graphics Corporation | Distributed autorouting of conductive paths |
Also Published As
Publication number | Publication date |
---|---|
DE3239210C2 (fr) | 1991-01-31 |
FR2515206B1 (fr) | 1988-10-14 |
FR2515206A1 (fr) | 1983-04-29 |
JPS58155079A (ja) | 1983-09-14 |
DE3239210A1 (de) | 1983-05-26 |
SU1440352A3 (ru) | 1988-11-23 |
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