JPH02124170A - Blood storage vessel - Google Patents

Abstract

PURPOSE:To safely remove the air bubbles in a 2nd blood inflow part without ejecting the internal blood to the outside by providing a communicating port which communicates the upper part of the 2nd blood inflow part and the inside of a blood treating part or a 1st blood inflow part. CONSTITUTION:The blood removed from the vena cava flows from a 2nd blood inflow port 9 into the 2nd blood inflow part 10, flows out of a tricot bag 23 enclosing the outer periphery, flows down on the inside surface of a deflector 13 and accumulates in a blood storage part 11. The blood emitted in the operation field in cardiotomy flows from the 1st blood inflow port 5 into the 1st blood inflow part 6, passes a blood filter member 20 and a defoaming member 21 and flows into the deflector 13. The air bubbles and bubbling blood gathered in the upper part of the blood stored in the 2nd blood inflow part 10 flow out of the communicating port 8 and flow into the spacing between the filter member 20 and the defoaming member 21 where the blood is defoamed; thereafter, the blood flows out of the blood treating part 7, flows into the deflector 13 and flows down into the storage part 11.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a blood reservoir for temporarily storing blood in an extracorporeal blood circulation circuit used in an artificial lung or the like.

[Prior Art] In recent years, extracorporeal circulation circuits incorporating artificial lungs have been used in place of living lungs to remove carbon dioxide from blood and add oxygen to blood during open heart surgery. In such an extracorporeal circulation circuit incorporating an oxygenator, blood that is being circulated extracorporeally is stored, and it is used to remove air bubbles if they enter the circuit, or in case the circulating blood volume decreases due to a break in the circuit tube, etc. A blood reservoir is attached to the.

FIG. 6 shows a circuit diagram of a conventional heart-lung machine. Blood removed from the vena cava of the human body passes through the venous line 40 and flows into the blood reservoir 42 . In addition, blood in the thoracic cavity and blood in the heart cavity that bleed in the surgical field flows into the cardiotomy reservoir 44 via the suction line 43 by the pump 45, and then foreign substances such as thrombi, microaggregates, and air bubbles in the blood are removed. After being removed, blood is sent to the blood storage tank 42. Then, the blood stored in the blood storage tank 42 is transferred to a pump 46.
The blood is then sent to an oxygenator with a heat exchanger 48, where it is temperature-adjusted and gas exchanged, and then returned to the aorta of the human body via an arterial line 50. As described above, in the conventional heart-lung bypass circuit, the cardiotomy reservoir 45 coexists in addition to the blood reservoir 42, which increases the amount of extracorporeal circulating blood during open-heart surgery, and also causes the coexistence of the blood reservoir and the cardiotomy reservoir 45. Therefore, the blood circuit becomes complicated, and during the surgery, it is necessary to maintain the blood level of both patients at a safe level that does not involve bubbles, which is not easy to manage.

As shown in Japanese Patent Application Laid-Open No. 61-276562, the applicant has proposed a system in which a blood storage tank and a cardiotomy reservoir are integrated.

This blood reservoir solves the above problems and has sufficient effects. However, in this blood storage tank, in order to remove air bubbles stored in the upper part of the blood removal line chamber (venous blood chamber), a communication port is provided that communicates the end of the blood removal line chamber with the outside. When this communication port is opened during use, blood in the blood removal line chamber sometimes spurts out.

Therefore, an object of the present invention is to integrate the functions of a blood storage tank and a cardiotomy reservoir, and to integrate the functions of a blood removal line chamber (
To provide a blood reservoir in which air bubbles accumulated in the upper part of a venous blood chamber can be safely removed without the blood inside gushing out to the outside.

[Means for Solving the Problems 1] What achieves the above object is a housing, a first blood inlet provided in the upper part of the housing, and a first blood inlet communicating with the first blood inlet. a blood inlet, a blood processing part configured to allow blood flowing into the first blood inlet to pass therethrough and having a filtering and defoaming function, and a second blood inlet communicating with the inside of the housing. , a second blood inflow part that communicates with the second blood inflow port, and a communication port that communicates between the upper part of the second blood inflow part and the inside of the blood processing part or the first blood inflow part; (a) for storing blood flowing out from the blood processing section and the second blood inflow section;
This is a blood storage tank having a blood storage part provided at the lower part of the housing and a blood outlet communicating with the lower part of the blood storage part.

Further, the second blood inflow portion is provided near the opening of the second blood inflow port in the blood inflow portion, and is configured to suppress blood inflow to suppress spouting of blood that has flowed in from the second blood inflow port. It is preferable to ff the part. In addition, the second
Preferably, the blood inlet port projects into the housing from below the housing. Furthermore, the blood processing section surrounds the outer periphery of the first blood inflow section, a blood filtration member provided to surround the first blood inflow section, and a blood filtration member that surrounds the blood filtration member. It is preferable that the blood defoaming member is provided. Furthermore, it is preferable that the communication port communicates between the blood filtering member and the blood defoaming member and the second blood inflow portion.

The blood reservoir of the present invention will be explained in detail using embodiments shown in the drawings.

The blood storage tank 1 of the present invention includes a housing 2, a first blood inlet 5 provided at the upper part of the housing 2, a first blood inlet 6 communicating with the first blood inlet 5, and a first blood inlet 6 that communicates with the first blood inlet 5. A blood processing section 7 having a filtering and defoaming function configured to allow blood flowing into the blood inflow section 6 of the housing 2 to pass therethrough;
a second blood inflow port 1° that communicates with the inside of the second blood inflow port 9; a second blood inflow port 1° that communicates with the second blood inflow port 9; A communication port 8 that communicates with the inside of the first blood inflow section 6, a blood storage section 11 provided at the lower part of the housing that stores blood flowing out from the blood processing section 3 and the second blood inflow section 10, It has a blood outflow port 12 that communicates with the lower part of the portion 11.

In particular, since the communication port 8 that communicates between the upper part of the second blood inflow part 10 and the inside of the blood processing part 7 or the first blood inflow part 6 is provided, air bubbles accumulated in the upper part of the second blood inflow part 1o can be removed. can be safely removed without spouting the blood inside the second blood inflow part to the outside.

DESCRIPTION OF THE PREFERRED EMBODIMENTS The blood reservoir of the present invention will be described in detail below using embodiments shown in FIGS. 1 to 4.

1 is a partial sectional view showing an embodiment of the blood storage tank of the present invention, FIG. 2 is a top view of the blood storage tank shown in FIG. 1, and FIG. 3 is a top view of the blood storage tank shown in FIG. 1. 4 is a cross-sectional view taken along the line ■--I in FIG. 1. FIG.

The blood storage tank 1 of the present invention in this embodiment includes a housing 2, a lid 3, an inner cylinder 4, a blood processing section 7 having defoaming and blood filtration functions, and the like.

The housing 2 has a substantially cylindrical shape and is open at the top. The bottom portion has a blood outflow port 12 formed at the peripheral edge of the bottom portion, and the bottom portion is inclined toward the blood outflow port 12. The upper part of this blood outflow port 12 forms a blood storage part it. Furthermore, a second blood inlet 9 is provided at the center of the bottom of the housing 2 and projects vertically toward the top of the interior of the housing 2 . It is preferable that the housing 2 allows easy confirmation of the blood stored therein, and is preferably made of a hard transparent material. Examples of materials for forming the housing 2 include hard vinyl chloride resin, styrene resin,
Polycarbonate and the like can be suitably used.

The second blood inlet 9 communicates with a second blood inlet 10 . Inside the second blood inflow portion 10 and above the blood inflow port 9, there is provided a baffle plate 24 formed so that the blood flowing in from the second blood inflow port 9 comes into contact with the baffle plate 24. It is being This baffle plate 24 suppresses bubbling of the blood stored in the second blood inflow section caused by blood rapidly flowing into the blood inflow section from the second blood inflow port. Therefore, this baffle plate 24 regulates the flow path of blood flowing in from the second blood inflow port. The baffle plate 24 has a substantially disk shape, and is provided so that its circular surface is substantially parallel to the opening of the second blood inflow port 9. The baffle plate 24 is provided in the middle of a member 26 having a cross-shaped cross section as shown in FIGS. 1 and 4. The cross-shaped tip of this member 26 is fixed by a fixing part 22a provided at the center of the disc-shaped member 22, which will be described later. Further, a cylindrical portion 26b is provided at the lower end of the member 26.
is provided, and this cylindrical portion 26b is fitted onto the protrusion forming the second blood inlet 9 and fixed.

Further, a deflector 1 is provided on the outer periphery of the second blood inflow portion 10.
3 is provided. The deflector 13 has a cylindrical shape whose diameter decreases downward, and its upper and lower ends are open. A plurality of protrusions 13a are provided on the inner surface of the upper opening of the deflector 13. This protrusion 1
3a forms a mounting portion for a disk-shaped member 22, which will be described later. Moreover, the inner surface and lower end opening of the deflector 13 are
A flow path for blood flowing out from the second blood inflow portion and the first blood inflow portion is formed. A plurality of protrusions 13b are also provided on the inner surface of the opening at the lower end.
engages with a stepped portion formed on the side wall of the blood inlet 9,
The deflector 13 is configured to be concentric with the second blood inlet.

The lid 3 is fitted into the upper opening of the housing 2, as shown in FIG. The lid body 3 has a first blood inflow port 5
have. Further, this first blood inflow port 5 is connected to a second blood inflow port 5.
As shown in the figure, a plurality of them are provided. Furthermore, the lid body 3 is provided with a briming boat 18, a rapid briming boat 19, and a gas discharge port 16. The rapid briming boat 19 is used to inject liquid, such as blood, to raise the blood level when the blood level in the blood reservoir rapidly drops due to blockage of a tube or the like and becomes dangerous. used.

A blood processing section 7 having an inner cylinder 4 inside the upper part is provided below the lid 3. The inner cylinder 4 has a funnel shape, and the inside of the funnel-shaped part communicates with the first blood inlet 5 . is formed. This blood introduction part 28
has the function of suppressing the blood flowing in from the blood inflow port 5 from falling directly below the inner cylinder 4, forming a substantially swirling flow, and bringing the blood into contact with the entire blood processing section 7, which will be described later. There is. As shown in FIGS. 1 and 3, the inner cylinder 4 has a plurality of slits 30 extending upward from the lower end.

Therefore, the blood flow that flows into the blood introduction part 2G from the first blood inflow port 5 and becomes a substantially swirling flow flows into the first blood inflow part 6 through the slit 30 and the lower end of the inner cylinder 4.

Then, the blood flows into the first blood inflow section 6. While the liquid passes through the blood processing section 7, it is defoamed and foreign substances are filtered out.

The blood processing section 7 has an adhesive 15 on the upper outer periphery of the inner tube 4.
It is fixed liquid-tightly by a. Further, the lower end of the blood processing section 7 is liquid-tightly fixed to a disk-shaped member 22 forming the upper part of the second ll'll liquid inflow section 1o by an adhesive 15b. As the adhesive, curable resins such as polyurethane and silicone rubber are preferably used. Blood processing section 7
is composed of a filtering member 20 for filtering foreign substances such as blood clots and microaggregates, and a defoaming member 21 coated on the outer periphery of the filtering member 2o. The outer periphery is covered with a tricot bag 23. As the tricot bag 23, a woven fabric such as polyethylene terephthalate or nylon is preferably used. The upper part of this tricot bag 23 is fixed to the outer circumferential end of the inner tube 4 by a band 14a, and the lower end is fixed to the outer circumference of a cylindrical part 26a installed at the lower end of the member 26 by a band 14b. There is. In particular, in this embodiment, the upper and lower ends of the filter member 20 are fixed liquid-tightly with an adhesive. Furthermore, a disk-shaped member 22 that forms the lower end of the first blood inflow part 6 and the upper end of the second blood inflow part 10 is provided at the center of the lower end of the blood processing part 7 . The disk-shaped member 22 has a second blood inflow section 1 .
A communication port 8 is provided that communicates the two parts of the blood processing section 7 with the inside of the blood processing section 7. It is preferable to provide a plurality of communication ports 8, as shown in FIG. 3, and it is further preferable to provide the communication ports 8 at positions that face each other. In the blood storage tank of this embodiment, as shown in FIG. 3, a pleated filtration member (filter) 20 is used as the filtration member to ensure a wide filtration area, and a defoaming member is used. 21 is
A cylindrical member is used which envelops the outer periphery of the filter member 20 which is pleated. And the above communication []
8 is a protrusion 17 between the filter 20 and the defoaming member 21
ing. Therefore, the bubbled blood in the second blood inflow part IO and the blood J-1 in the second blood inflow part 10
The blood containing air bubbles that moved towards the
After flowing into the blood processing section 7 through L3, the blood passes through the defoaming member 21, so that bubbles and air contained in the blood can be removed.

As the filter used for the filtration member 20, a mesh made of nylon, polyester (eg, polyethylene terephthalate), polypropylene, polyethylene, etc., a nonwoven fabric, a porous membrane, etc. are used.

Preferably, the basis weight is 150 to 250 Lil/x'
Polyethylene I/Nterephthalate nonwoven fabric. Also,
As the defoaming member 21, a foam is used, and for example, foam, cellulose foam, nylon foam, etc. are preferably used. Preferably, it is urethane foam. Furthermore, it is preferable that the antifoaming member 21 be coated with an antifoaming agent. As the antifoaming agent, oils can generally be used, and silicone oil can be particularly preferably used.

Further, a check valve may be provided in the communication port 8 so that the blood flowing inside the blood processing section 7 does not flow into the second blood inflow section 10. Considering the pressure during use, the second blood inflow part side is higher than the first blood inflow part 6 and the blood processing part 7 side, so the communication port 8 is normally lower than the blood processing part 7.
Although it is thought that blood will not flow into the second blood inflow section 26 through the second blood inflow section, for safety reasons, a check valve may be provided that only allows blood to flow out from the second blood inflow section. .

Further, in the above description, an example has been described in which the communication port 8 is provided inside the blood processing section 7, but the communication port 8 is not limited to this.
may communicate with the inside of the first blood inflow section 6. In this case as well, a check valve that only allows blood to flow out from the second blood inflow portion may be provided for safety.

Next, an embodiment of the blood reservoir of the present invention will be described.

(Example) As a housing, the inner diameter of the opening is about 155 xi.

The length up to the blood outflow port formed at the lower end was approximately 330xx, the center of the bottom was concave, and the entire bottom surface was inclined toward the blood outflow port, and was made of polycarbonate. Then, a second blood inlet was attached to the recess.

The inner cylinder has a length of approximately 7511 mm and an upper diameter of approximately 150 ix.
A device having the shape shown in FIG. 1 was made using polycarbonate. A polyethylene terephthalate nonwoven fabric with a basis weight of about 200 y/x' was used as a filter for the blood processing section. Moreover, a polyurethane foam (approximately 20 bore/ax) was used as the defoaming member. A polyethylene terephthalate woven fabric was used as the tricot bag. In addition, the deflector is made of ABS resin, with an upper diameter of approximately 110 yx and an upper diameter of approximately 40 yx.
I created one of m. Then, the upper and lower parts of the filter were fixed to the upper part of the inner cylinder and the disc-shaped member using polyurethane, and the antifoaming member was further fixed around the filter. The disk-shaped member used had a cross-sectional shape as shown in FIG. 1, and further had two communication ports protruding upward near the peripheral edge. Furthermore, below this disc-shaped member, a member having a cross-shaped cross section, a baffle plate in the middle, and a cylindrical portion at the lower end was attached. The entire assembly is wrapped in a tricot bag, the upper part is fixed to the side wall near the outer periphery of the end of the inner cylinder with a band made of nylon, and the lower part is attached to a cylindrical bag provided at the lower end of a member having a cross-shaped cross section. It was fixed to the side wall of the shaped part with a band. Then, a lid body having a shape as shown in FIG. 1 was formed from polycarbonate, and the above-mentioned inner cylinder was fused to the lower part of this lid body. Then, put the deflector into the housing,
The end of the second blood inlet protruding from the inner bottom surface of the housing was fixed to the lower part of this assembly. Then, the lid and the housing were fixed together to create a blood reservoir of the present invention as shown in FIG. 1. The volume of this blood reservoir was approximately 4ρ.

(Comparative Example) As a disc-shaped member fixed to the lower end of the filter, one was used in which the two communication ports near the periphery were not provided, and the communication port was provided in the center. Then, a tube made of silicone rubber was fixed to this communication port, and the end of this tube was fixed in a liquid-tight manner to a rapid priming boat provided on the lid. Other than the above, using the same thing as the example,
A comparative blood reservoir was created.

(Experiment) Next, an experiment conducted using a blood reservoir according to an example of the present invention and a blood reservoir according to a comparative example will be described.

In this experiment, a blood circuit as shown below was used. The second blood inlet of the blood reservoir was connected to the blood reservoir via a tube, and a pump was provided in the middle of the tube. Also,
The blood outlet of the blood storage tank and the blood storage container were connected with a tube. Then, an air injector for blowing air into the blood is connected to the tube connected to the second blood inlet.1. Ta. Live blood (H
t35%), and the amount of blood delivered was 4 Q, /+ using a pump.
It was set as nin. Air is injected into the blood from the air injector at a rate of 50cc/15sec, and approximately 1.
0. blood was allowed to accumulate.

In the blood reservoir of the comparative example, about 2 minutes after the start of blood circulation, a spurt of more frothy blood was observed in the rapid briming bowl 1, which was connected to the second blood inflow part through the tube. In contrast, in the blood reservoir of the example of the present invention, no abnormality was observed even 5 minutes after the start of circulation.

[Function 1] The function of the blood reservoir of the present invention will be explained using the embodiment shown in FIG. 1 and the artificial heart-lung circuit diagram shown in FIG.

As shown in FIG. 5, blood removed from the vena cava of the human body passes through the venous line 33 and flows from the second blood inlet 9 into the second blood inlet IO inside the blood reservoir l. At this time, the blood flowing in from the second blood inlet 9 flows through the baffle plate 2.
4 and then flows into the inflow portion 24, so the second
The blood stored in the blood inflow portion IO is less likely to be foamed. Then, the blood inside the blood inflow part 10 sequentially flows down the tricot that covers the outer periphery of the second blood inflow part 10, and passes from the lower end of the deflector 13 to the blood storage part 11.
to be stored. In addition, blood in the surgical field during open heart surgery (1), intrathoracic blood, intracardiac blood, and blood filling the left ventricle and left atrium are removed from the suction line 31 and the pump 32.
The blood flows through the first blood inlet 5 of the blood storage tank 1 into the blood introduction part 28 , passes through the inner tube 4 , and flows into the first blood inflow part 6 . The blood that has flowed into the first blood inflow section 6 passes through the blood filtration member 20 that constitutes the blood processing section 7,
Blood clots, microaggregates, etc. are removed, and
After being defoamed through the defoaming member 21, the blood flows out from the blood processing section 7, flows into the deflector 13 from the upper part of the deflector 13 7, and flows out from the second blood inflow section IO flowing on the inner surface of the deflector 13 (1).

The blood flows into the blood storage section 11. and,
The air bubbles and bubbling blood collected in the second blood inflow part 10 are stored in the second blood inflow part 10.
As the blood level rises by 1L, it rises and eventually flows out from the communication port 8, and the filtering member 20 and defoaming member 21 in the blood processing section 7
(7) After being defoamed by the defoaming member 21, the blood flows out from the blood processing section 7 and passes through the first blood inflow section 6, together with the blood flowing into the deflector 13 as described above.
and flows down into the storage section 11. The blood stored in the blood storage part 11 of the blood storage tank 1 is sent to the oxygenator with a heat exchanger 36 by the pump 34, and after adjusting the blood temperature, removing carbon dioxide, and adding oxygen, it is transferred to the arterial line. 38
The blood is then sent to the aorta of the human body.

[Effects of the Invention] The blood storage tank of the present invention includes a housing, a first blood inlet provided in two parts of the housing, and a first blood inlet communicating with the first blood inlet. , a blood processing section having a filtering and defoaming function configured to allow blood flowing into the first blood inflow section to pass therethrough; a second blood inflow communicating with the interior of the housing; a second blood inflow port that communicates with a second blood inflow port; a communication port that communicates between the second part of the second blood inflow port and the blood processing section or the inside of the first blood inflow port; It has a blood storage section provided at a lower part of the housing for storing blood flowing out from the blood processing section and the second blood inflow section, and a blood outflow port communicating with the lower part of the blood storage section. Since the functions of the blood reservoir and the cardiotomy reservoir are integrated, there is no need to provide a blood reservoir separate from the cardiotomy reservoir, and the amount of extracorporeal circulating blood during open heart surgery can be reduced. The blood circuit can be made simple. Furthermore, during open-heart surgery, the blood level in the blood reservoir can be checked with just one blood reservoir, making management easier. Furthermore, in the blood reservoir of the present invention,
In particular, since a communication port is provided that communicates the part of the second blood inflow part with the blood processing part or the inside of the first blood inflow part, the second
Air bubbles and bubbling of blood accumulated in the upper part of the second blood inflow part can be safely removed without causing the blood inside the second blood inflow part to spout to the outside.

[Brief explanation of drawings]

FIG. 1 is a partial sectional view showing an embodiment of the blood storage tank of the present invention, FIG. 2 is a top view of the embodiment shown in FIG. 1, and FIG. 3 is a line 1-1 in FIG. 1. The cross-sectional view, Figure 4, is from ■-■ in Figure 1.
A line sectional view, FIG. 5 is a circuit diagram of an artificial heart-lung machine using the blood reservoir of the present invention, and FIG. 6 is a circuit diagram of an artificial heart-lung machine using a conventional blood reservoir and a cardiotomy reservoir. DESCRIPTION OF SYMBOLS 1... Blood storage tank 2... Housing 3... Lid body 4... Inner tube 5... First blood inlet 6... First blood inflow part 7... Blood processing part 8...Communication port 9...Second blood inlet IO...Second blood inflow part U...Blood storage part 12...Blood inflow port 13...
・Deflector 20...Blood filtering member 21...
Blood defoaming member 22...Disc-shaped member 24...Baffle plate

Claims (5)

[Claims] (1) A housing, a first blood inlet provided at the top of the housing, a first blood inlet communicating with the first blood inlet, and blood flowing into the first blood inlet. a blood processing section configured to allow blood to pass therethrough and having a filtration and defoaming function; and a second blood processing section that communicates with the interior of the housing.
a blood inflow port, a second blood inflow port communicating with the second blood inflow port, and an upper part of the second blood inflow port communicating with the inside of the blood processing section or the first blood inflow port. a blood storage part provided at a lower part of the housing for storing blood flowing out from the blood processing part and the second blood inflow part, and a blood outflow port communicating with the lower part of the blood storage part. A blood reservoir characterized by having. (2) The second blood inflow part is provided near the opening of the second blood inflow port in the blood inflow part, and includes a baffle plate that suppresses spouting of blood that has flowed in from the second blood inflow port. The blood reservoir according to claim 1. (3) The second blood inlet port projects into the housing from below the housing.
Blood reservoir as described. (4) The blood processing section includes a blood filtration member provided so as to surround the outer periphery of the first blood inflow section and a blood defoaming member provided so as to surround the blood filtration member. The blood reservoir according to any one of claims 1 to 3. (5) The blood storage tank according to claim 4, wherein the communication port communicates between the blood filtering member and the blood defoaming member and the second blood inflow portion.