JPH01199912A - Substance useful as medicine - Google Patents
Substance useful as medicineInfo
- Publication number
- JPH01199912A JPH01199912A JP63024696A JP2469688A JPH01199912A JP H01199912 A JPH01199912 A JP H01199912A JP 63024696 A JP63024696 A JP 63024696A JP 2469688 A JP2469688 A JP 2469688A JP H01199912 A JPH01199912 A JP H01199912A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- diseases
- treating
- pearl
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 title claims abstract description 17
- 239000003814 drug Substances 0.000 title abstract description 18
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000011049 pearl Substances 0.000 claims description 8
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract description 9
- 229910001424 calcium ion Inorganic materials 0.000 abstract description 9
- 201000010099 disease Diseases 0.000 abstract description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 9
- 229940079593 drug Drugs 0.000 abstract description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 5
- 206010020772 Hypertension Diseases 0.000 abstract description 5
- 229910052791 calcium Inorganic materials 0.000 abstract description 5
- 239000011575 calcium Substances 0.000 abstract description 5
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 5
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 abstract description 5
- 201000004647 tinea pedis Diseases 0.000 abstract description 5
- 230000036541 health Effects 0.000 abstract description 4
- 208000014617 hemorrhoid Diseases 0.000 abstract description 3
- 230000001766 physiological effect Effects 0.000 abstract description 3
- 230000002459 sustained effect Effects 0.000 abstract description 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000025301 tympanitis Diseases 0.000 abstract 1
- 206010033078 Otitis media Diseases 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000003779 hair growth Effects 0.000 description 3
- 239000012907 medicinal substance Substances 0.000 description 3
- 201000001245 periodontitis Diseases 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 206010002383 Angina Pectoris Diseases 0.000 description 2
- 208000001034 Frostbite Diseases 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 230000007721 medicinal effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 241000242757 Anthozoa Species 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 235000014653 Carica parviflora Nutrition 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 241000212342 Sium Species 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 208000004631 alopecia areata Diseases 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 108010006161 conchiolin Proteins 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000008821 health effect Effects 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は高血圧、糖尿病、心臓病等の内科的疾患、痔、
中耳炎、凍傷、水虫、養毛等の外科的皮膚科的疾患等広
範囲の疾病の治療あるいけ予防のための医薬、あるい＃
−ｉ健康維持のための保健薬として有用な物質に関する
ものである。[Detailed Description of the Invention] [Industrial Application Field] The present invention is applicable to medical diseases such as hypertension, diabetes, heart disease, hemorrhoids,
Medicines for the treatment or prevention of a wide range of diseases such as otitis media, frostbite, athlete's foot, surgical dermatological diseases such as hair growth, etc.
-i It relates to substances useful as health medicines for maintaining health.
従来から活性カルシウムイオンを含有する水は医薬ある
いは保健薬的な作用、効果を有することが知られている
。このような活性カルシウムイオンを含有する水はカル
シウムを含有する水を！気分解することによって得られ
る。It has been known that water containing active calcium ions has medicinal or health effects. Water containing such active calcium ions is water containing calcium! Obtained by gas decomposition.
しかしながら上記活性力〃シウムイオンを含有する水を
製造するには電気分解装置と言う高価な装置が必要であ
り、また生ずる活性カルシウムイオンに長期にわ念る持
続性がない。However, in order to produce water containing active calcium ions, an expensive device called an electrolyzer is required, and the produced active calcium ions do not have the desired long-term sustainability.
本発明は上記従来の問題点を解決する手段として、真珠
を加熱することにより長期にわたって持続的に活性力〃
シウムイオンを発生する物質を得るものである。The present invention is a means to solve the above-mentioned conventional problems by heating pearls to maintain their vitality over a long period of time.
This is to obtain a substance that generates sium ions.
本発明においては真珠は加−に際して通常粉末吠１粒状
あるいけフレーク状等に！！！細化される。In the present invention, the pearls are usually shaped into powder grains or flakes when added. ! ! Be refined.
このように微細化された真珠は所定の温度で加熱せられ
るが、得られる物質の医薬的効果を最大とするには該加
熱温度は４００〜１５００℃であることが望ましく、更
に望ましくけ加熱温度は６５０〜９６０℃である。The pearls thus refined are heated at a predetermined temperature, and in order to maximize the medicinal effects of the obtained substance, the heating temperature is preferably 400 to 1500°C, and more preferably the heating temperature is is 650-960°C.
このようにして医薬として卓効のある本発明の物質が得
られる力ζ本発明の物質には貝殻、サンゴ、動物の骨、
甲殻類の甲羅等のカルシウム含有物を本発明の物質と同
様にして加熱処理した物質を混合してもよい。更に本発
明の物質には鎮痛剤。In this way, the substance of the present invention which is highly effective as a medicine can be obtained.The substance of the present invention includes shells, corals, animal bones,
A substance obtained by heat-treating a calcium-containing substance such as the shell of a crustacean in the same manner as the substance of the present invention may be mixed. Additionally, the substances of the invention are analgesics.
消炎剤、抗生物質等の他の医薬、あるいけ清涼剤。Other medicines such as anti-inflammatories, antibiotics, and coolants.
増量剤、結着剤等の他の添加剤が添加されてもよい。Other additives such as fillers, binders, etc. may be added.
本発明の物質は粉状２粒状、フレーク状、あるいけダブ
レフト等の形状として経口薬として、またペースト、ク
リーム等のベースに混合して塗布薬として提供される。The substance of the present invention can be provided as an oral medicine in the form of powder, flakes, double left, or the like, or as a liniment by mixing it with a base of a paste, cream, or the like.
本発明の医薬として有用な物質は生物活性効果を有する
から高血圧、糖尿病、心臓病等積々の内科的疾患の治療
薬、予防薬あるいは保健薬として有用であり、また養毛
剤、白髪止め剤等としても有用であるとともに殺菌、消
画効果等を有するから、痔、中耳炎、凍傷、水虫、しみ
そげかす等の外科的皮膚科的疾患の治療薬や予防薬とし
ても有用である。The substance useful as a medicine of the present invention has a biologically active effect, and is therefore useful as a therapeutic, preventive, or health drug for a number of medical diseases such as hypertension, diabetes, and heart disease, and as a hair tonic, anti-grey agent, etc. Since it is also useful and has sterilizing and eradicating effects, it is also useful as a therapeutic or preventive agent for surgical and dermatological diseases such as hemorrhoids, otitis media, frostbite, athlete's foot, and scabies.
真珠を加熱すると該真珠中に含まれるカルシウム分が活
性化するものと思われる。そして本発明の物質を生体に
投与すると生体内において活性カルシウムイオンを除々
に発生し長期にわたって該活性カルシウムイオンの持続
的生理効果が発現される。真珠内ではカルシウムはコン
キオリン蛋白質含有燐酸カルシウムとして存在し、この
ような存在形顔が活性カルシウムイオンの持続的生理効
果に大きな役割を果しているように思われる。It is thought that heating the pearl activates the calcium contained in the pearl. When the substance of the present invention is administered to a living body, active calcium ions are gradually generated in the living body, and the active calcium ions exert a sustained physiological effect over a long period of time. In pearls, calcium exists as calcium phosphate containing conchiolin protein, and this form of existence appears to play a major role in the sustained physiological effects of active calcium ions.
実施例１（高血圧の治療）
真珠粉を７５０〜８５０℃で１０時間加熱して得た医薬
物質を血圧最高値約２１０、最低値約１８０の高血圧患
者に毎日０．５ｇ服用させたところ、６ケ月後には骸患
者の血圧最高値約１８０、最低値約８６となり、以後し
医薬物質の服用を中止しても血圧は路上記数値に安定し
た。Example 1 (Treatment of Hypertension) When a hypertensive patient with a maximum blood pressure of about 210 and a minimum blood pressure of about 180 took 0.5g of a medicinal substance obtained by heating pearl powder at 750 to 850°C for 10 hours every day, 6. After several months, Mukuro's blood pressure reached a maximum of about 180 and a minimum of about 86, and even after he stopped taking the drug, his blood pressure remained stable at the above-mentioned values.
実施例２（糖尿病の治療）
血糖値約４００の糖尿病患者に実施例１の医薬物質を毎
日０．５ｇ服用させたところ、８週間後にＦｉ卑糖値け
９５となり、以後該医薬物質の服用を中止しても血糖値
は路上記数値に安定した。Example 2 (Treatment of Diabetes) When a diabetic patient with a blood sugar level of about 400 was given 0.5 g of the pharmaceutical substance of Example 1 daily, the Fi base sugar level became 95 after 8 weeks, and the patient was unable to take the pharmaceutical substance from then on. Even after discontinuing treatment, blood sugar levels remained stable at the values listed above.
実施例８（歯槽膿漏の治療）
実施例１の医薬物質を歯槽膿漏患者の歯ぐきに１日１回
少量擦り込んだところ、８日目には歯ぐきからの膿の滲
出、出血がなくなり口臭も消失した。更に４週間後には
歯ぐきがしまった状態になり歯槽膿漏の完治をみた。Example 8 (Treatment of alveolar pyorrhea) When a small amount of the medicinal substance of Example 1 was rubbed into the gums of a patient with alveolar pyorrhea once a day, pus exudation and bleeding from the gums disappeared and bad breath disappeared on the 8th day. has also disappeared. After another 4 weeks, the gums became tight and the pyorrhea completely healed.
実施例４（水虫の治療）
実施例１の医薬物質６０重量％と酸化亜鉛５０重量％の
混合粉末を水虫の患部に１日１回少量擦り込んだところ
８日目にはかゆみが止り１週間の連続塗布で完治した。Example 4 (Treatment of Athlete's Foot) When a small amount of the mixed powder of 60% by weight of the pharmaceutical substance of Example 1 and 50% by weight of zinc oxide was rubbed into the affected area of athlete's foot once a day, the itching stopped on the 8th day and continued for 1 week. It was completely cured with continuous application.
実施例６（狭心症の治療）
狭心症の患者に１日２回、朝夕０．５ｇずつ実施例１の
医薬物質を服用さ訃たところ、１ケ月後には発作をみな
くなり、２ケ月後には心電図にて異常がみらｈなかった
。Example 6 (Treatment of angina pectoris) When a patient with angina pectoris took 0.5 g of the pharmaceutical substance of Example 1 twice a day in the morning and evening, he did not have an attack after 1 month, and the patient did not have an attack for 2 months. Afterwards, no abnormality was observed in the electrocardiogram.
実施例６（中耳炎の治療）
中耳炎の患者に１日２回、朝夕０．５ｇずつ実施例１の
医薬物質を服用させたところ、１ケ月後には耳内からの
滲出水をみなくなり聴力も顕著に回復した。Example 6 (Treatment of otitis media) When a patient with otitis media was given 0.5 g of the pharmaceutical substance of Example 1 twice a day in the morning and evening, the exudate from the ear ceased and his hearing became noticeable after one month. recovered.
実施例７（白髪止め）
完全に白髪である被処理者に実施例１の医薬物質を毎日
０．５ｇ服用させたところ４ケ月後には白髪中に２割程
度の黒髪の成育が認めらねた。Example 7 (prevention of gray hair) When a subject with completely gray hair was given 0.5 g of the pharmaceutical substance of Example 1 every day, after 4 months, about 20% of black hair among the gray hair was not observed to grow. .
実施例８（養毛）
円形脱毛症の患者に実施例１の医薬物質を１日２回、朝
夕０．５ｇずつ服用させたところ、１ケ月後には脱毛部
分に発毛をみた。Example 8 (Hair growth) When a patient suffering from alopecia areata took 0.5 g of the pharmaceutical substance of Example 1 twice a day in the morning and evening, hair growth was observed in the bald areas one month later.
実施例９（切傷の治療）
手の指の切傷に実施例１の医薬物質を１日８回少量塗布
したところ化膿することなく、８回目には全治した。Example 9 (Treatment of Cuts) When a small amount of the medicinal substance of Example 1 was applied to a cut on a finger of a hand 8 times a day, no suppuration occurred and the cut was completely cured by the 8th application.
特許出願人 加 藤 正 俊 加藤 益浩Patent applicant Masatoshi Kafuji Masuhiro Kato
Claims (1)
薬として有用な物質A medicinally useful substance obtained by heating pearls
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63024696A JPH01199912A (en) | 1988-02-04 | 1988-02-04 | Substance useful as medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63024696A JPH01199912A (en) | 1988-02-04 | 1988-02-04 | Substance useful as medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH01199912A true JPH01199912A (en) | 1989-08-11 |
Family
ID=12145334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63024696A Pending JPH01199912A (en) | 1988-02-04 | 1988-02-04 | Substance useful as medicine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01199912A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100397682B1 (en) * | 2001-02-26 | 2003-09-13 | 송선자 | Ionized calcium and ionized calcium water made of pearl shell and preparation method of the same |
| WO2022257693A1 (en) * | 2021-06-07 | 2022-12-15 | 河北以岭医药研究院有限公司 | Traditional chinese medicine composition for treating hypertension and preparation method therefor |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01117833A (en) * | 1987-10-29 | 1989-05-10 | Masatoshi Kato | Biologically active substance |
| JPH01132529A (en) * | 1987-11-19 | 1989-05-25 | Takeo Kagitani | Remedy for disease of digestive organ |
-
1988
- 1988-02-04 JP JP63024696A patent/JPH01199912A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01117833A (en) * | 1987-10-29 | 1989-05-10 | Masatoshi Kato | Biologically active substance |
| JPH01132529A (en) * | 1987-11-19 | 1989-05-25 | Takeo Kagitani | Remedy for disease of digestive organ |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100397682B1 (en) * | 2001-02-26 | 2003-09-13 | 송선자 | Ionized calcium and ionized calcium water made of pearl shell and preparation method of the same |
| WO2022257693A1 (en) * | 2021-06-07 | 2022-12-15 | 河北以岭医药研究院有限公司 | Traditional chinese medicine composition for treating hypertension and preparation method therefor |
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