JPH01158412A - Cleaning and preserving liquid for contact lens - Google Patents

Abstract

PURPOSE:To incorporate a water soluble cation formed polymer into the title liquid so that the cleaning of a contact lens surface to get rid of the dirt such as sebum and protein secured onto said surface is effected simply by immersing and preserving the contact lens in said liquid and that a preserving effect is obtd. CONSTITUTION:The water soluble cation formed polymer is incorporated into the liquid. The water soluble cation formed polymer may be general water soluble cation formed polymers which include the polymers cationated from polysaccharides such as cation formed cellulose, cation formed starch, cation formed guagam, and cation formed tamarind as well as the derivatives obtd. by adding alkylene oxides such as propylene oxide and butyrene oxide of grindol, etc., thereto before or after cationation. The labor in cleaning and preserving of the contact lens at the time of the use thereof is thereby facilitated and the performance of the cleaning and preserving liquid is enhanced.

Description

[Detailed description of the invention] (Industrial application field) The present invention relates to a cleaning solution for contact lenses.

(Conventional technology and problems) Various contact lenses have been used in the past, but
Contact lenses can be roughly divided into two types: non-hydrophobic contact lenses and hydrous contact lenses. The cleaning and storage methods for these contact lenses are somewhat different, but when non-hydrocontaining contact lenses are worn in the eyes, their surfaces are contaminated mainly by ocular sebum, which is secretion in the eyes. Therefore, after removing the contact lens from the eye, it is necessary to promptly wash the contact lens to remove contaminants such as eye oil that have adhered to the surface.

Wearing incompletely cleaned contact lenses on the eyes can be a major cause of unpleasant symptoms such as cloudy vision, eye pain, and bloodshot eyes.

A method for cleaning contact lenses is usually to apply a cleaning solution made of a sulfate ester of higher alcohol needles to both surfaces of the lens, and then rub the solution with your fingers.

After cleaning, contact lenses are rinsed with tap water, physiological saline, etc., and then immersed and stored in a storage solution containing sodium chloride, a buffer, a disinfectant, etc.

Storing contact lenses in a storage solution is important in the case of hydrophilic contact lenses to maintain their hydrated state, but even in the case of non-hydrous contact lenses, it is important to preserve the hydrophilic surface of the lens. In addition to retaining contact lenses and reducing the discomfort felt by the cornea when worn on the eye, it is also possible to store contact lenses in a hygienic manner and prepare them for the next wearing in a clean state. It is preferable to preserve it by immersion.

As described above, when handling contact lenses, cleaning and storage must be performed separately using predetermined cleaning solutions and preservation solutions, respectively, which is very time-consuming. Furthermore, in cleaning, contact lenses are scrubbed with hands and fingers, which has the disadvantage of damaging the lens surface. Furthermore, contact lenses made of water-repellent or hydrophobic materials, such as silicone rubber, may be treated to make them hydrophilic, and when you scrub them with your fingers, these hydrophilic treatments are damaged. There were drawbacks that shortened the lifespan of the product.

The present invention δ was arrived at as a result of intensive studies aimed at simplifying the effort during cleaning and storage when using contact lenses, and improving the performance of the cleaning and storage solution.

(Means for Solving the Problems) That is, the present invention is a contact lens cleaning and preservation solution characterized by containing a water-soluble cationized polymer.

The water-soluble cationized polymer used in the present invention is -
In-shell water-soluble cationized polymers may be used, such as cationized natural polysaccharides such as cationized cellulose, cationized starch, cationized guar gum, and cationized tamarind, and ethylene oxide, propylene oxide,
Examples include alkylene oxides such as butylene oxide, or derivatives obtained by cationizing glycidol or the like or which are added afterward. Furthermore, cationized synthetic polymers such as cationized polyvinylpyrrolidone and cationized polyacrylic acid and derivatives thereof are also included. It is also possible to use a mixture of two or more cationized polymers.

The washing preservation solution of the present invention can be prepared by adding and dissolving a water-soluble cationized polymer in physiological saline or pure water. The amount added varies depending on the type of cationized polymer, degree of polymerization, degree of substitution, etc., but is usually in the range of 0.01 to 5% (wt%), preferably 0.01 to 2%. Addition m is 0.
If it is less than 0.001%, the effect of the present invention cannot be obtained, and if it is more than 5%, the viscosity of the cleaning preservation solution becomes too high, making it inconvenient to handle.

The cleaning and preservation solution of the present invention contains a water-soluble cationized polymer, and its bactericidal action causes IIA bacteria to propagate in the solution, so there is no need to add a bactericidal agent, but commonly used cleaning aids can be used. , am agent and other additives may be appropriately blended.

(Effects of the Invention) The cleaning and preservation solution for contact lenses of the present invention has both the functions of cleaning and preserving contact lenses, and by simply immersing and preserving the contact lenses in the solution, the eye fluid that adheres to the surface of the contact lenses can be removed. It cleans away impurities such as proteins and has excellent preservation effects.

Furthermore, the cleaning and preservation solution of the present invention maintains the hydrophilicity of the surface of the contact lens and suppresses the proliferation of bacteria, etc., and therefore does not particularly require the addition of a bactericidal agent.

(Examples) Next, the present invention will be explained with reference to examples, but the invention is not limited to the scope of the examples listed here.

Examples 1 to 6, Comparative Example Non-hydrous contact lenses were given to subjects for 1 day (12 hours)
The contact lenses, which were worn by the participants and contaminated with eye secretions, proteins, etc., were immersed for 8 hours in a cleaning and preservation solution prepared by dissolving various cationized polymers in the amounts shown in Table 1 in pure water. For comparison, a similar immersion test was conducted using a commercially available cleaning solution.

After the contact lenses that had undergone the immersion treatment were washed in running water for 1 minute, 10 subjects were asked to wear 6 contact lenses, and a sensory test was conducted. Table 1 shows the average results of the 10-level evaluation.

(Margin below) Table 1 Example 7 Contact lenses treated in the same manner as Examples 1 to 6 were washed in running water for 1 minute, and then observed whether the surface was covered with water.

As a result, the surfaces of the contact lenses crushed in the cleaning solutions of Examples 1 to 6 were uniformly covered with water and had good hydrophilicity, whereas the surfaces of the contact lenses crushed in the cleaning solutions of Examples 1 to 6 were uniformly covered with water and had good hydrophilicity. was observed repelling water.

Patent applicant Daicel Chemical Industries, Ltd. Agent Patent attorney Takashi Koshiba Procedure amendment
(Spontaneous) 1. Indication of the incident Patent Application No. 308716 filed in 1985 2. Name of the invention: Cleaning and preservation solution for contact lenses 3. Correcting 1. Relationship with the case Patent applicant address: 1 Teppo-cho, Sakai City, Osaka Prefecture Name (290) Daicel Chemical Industries, Ltd. Representative Yoshifumi Kubota's Gate Corrected to Mitsui Building.

Procedural amendment (method) % formula % 1. Indication of the case Patent Application No. 308716 of 1985 2. Name of the invention Cleaning preservation solution for contact lenses 3. Person making the amendment Relationship with the case Patent applicant address Osaka Prefecture 1 Teppo-cho, Sakai City Name (290) Daicel Chemical Industries, Ltd. March 31, 1988 6. Between lines 5 and 6 of page 1 of the specification of contents of the amendment, ``3. Add "Explanation".

Claims (1)

[Claims] A contact lens cleaning and storage solution containing a water-soluble cationized polymer.