JP7853288B2 - 新規ペプトイド及び慢性疼痛の予防又は治療におけるそれらの使用 - Google Patents

新規ペプトイド及び慢性疼痛の予防又は治療におけるそれらの使用

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Publication number
JP7853288B2
JP7853288B2 JP2023521558A JP2023521558A JP7853288B2 JP 7853288 B2 JP7853288 B2 JP 7853288B2 JP 2023521558 A JP2023521558 A JP 2023521558A JP 2023521558 A JP2023521558 A JP 2023521558A JP 7853288 B2 JP7853288 B2 JP 7853288B2
Authority
JP
Japan
Prior art keywords
peptoid
formula
trip8b
minutes
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2023521558A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023544842A5 (enExample
JP2023544842A (ja
Inventor
ビュセロール，ジェローム
ブリネ，エマニュエル
タイユフミエール，クロード
ロイ，オリビエ
ノートン，リオネル
アイソーニ，ユセフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Santé et de la Recherche Médicale
Original Assignee
Institut National de la Santé et de la Recherche Médicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Institut National de la Santé et de la Recherche Médicale filed Critical Institut National de la Santé et de la Recherche Médicale
Publication of JP2023544842A publication Critical patent/JP2023544842A/ja
Publication of JP2023544842A5 publication Critical patent/JP2023544842A5/ja
Application granted granted Critical
Publication of JP7853288B2 publication Critical patent/JP7853288B2/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2023521558A 2020-10-06 2021-09-30 新規ペプトイド及び慢性疼痛の予防又は治療におけるそれらの使用 Active JP7853288B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR2010186A FR3114739B1 (fr) 2020-10-06 2020-10-06 Nouveaux peptoides et leur utilisation dans la prevention ou le traitement de la douleur chronique
FR2010186 2020-10-06
PCT/FR2021/051694 WO2022074313A1 (fr) 2020-10-06 2021-09-30 Nouveaux peptoides et leur utilisation dans la prevention ou le traitement de la douleur chronique

Publications (3)

Publication Number Publication Date
JP2023544842A JP2023544842A (ja) 2023-10-25
JP2023544842A5 JP2023544842A5 (enExample) 2024-10-02
JP7853288B2 true JP7853288B2 (ja) 2026-04-28

Family

ID=74553909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023521558A Active JP7853288B2 (ja) 2020-10-06 2021-09-30 新規ペプトイド及び慢性疼痛の予防又は治療におけるそれらの使用

Country Status (8)

Country Link
US (1) US20230374067A1 (enExample)
EP (1) EP4225295B1 (enExample)
JP (1) JP7853288B2 (enExample)
CN (1) CN116744957A (enExample)
CA (1) CA3194875A1 (enExample)
ES (1) ES3005857T3 (enExample)
FR (1) FR3114739B1 (enExample)
WO (1) WO2022074313A1 (enExample)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019517530A (ja) 2016-06-07 2019-06-24 江蘇恒瑞医薬股▲ふん▼有限公司 フェニルプロパンアミド誘導体ならびにそれらの製造方法および医薬用途
JP2020505409A (ja) 2017-01-27 2020-02-20 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ 痛みの予防および治療に使用するための鎮痛効果を有する化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60100055T2 (de) * 2001-03-21 2003-07-24 Schwarz Pharma Ag Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen
KR20080038408A (ko) * 2005-08-18 2008-05-06 쉬바르츠파르마에이지 근육통 치료를 위한 펩티드 화합물의 신규한 용도
EP2289886A1 (en) * 2009-08-31 2011-03-02 Institut d'Investigacions Biomédiques August PI I Sunyer Peptoid agonists of nerve growth factor and their use as medicaments
US9216210B2 (en) * 2013-12-23 2015-12-22 Dublin City University Multiprotease therapeutics for chronic pain

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019517530A (ja) 2016-06-07 2019-06-24 江蘇恒瑞医薬股▲ふん▼有限公司 フェニルプロパンアミド誘導体ならびにそれらの製造方法および医薬用途
JP2020505409A (ja) 2017-01-27 2020-02-20 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ 痛みの予防および治療に使用するための鎮痛効果を有する化合物

Also Published As

Publication number Publication date
US20230374067A1 (en) 2023-11-23
EP4225295B1 (fr) 2024-11-13
EP4225295C0 (fr) 2024-11-13
CA3194875A1 (fr) 2022-04-14
CN116744957A (zh) 2023-09-12
EP4225295A1 (fr) 2023-08-16
ES3005857T3 (en) 2025-03-17
WO2022074313A1 (fr) 2022-04-14
JP2023544842A (ja) 2023-10-25
FR3114739B1 (fr) 2022-08-26
FR3114739A1 (fr) 2022-04-08

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