JP7840505B2 - 変形性関節症及び/又は関節リウマチの予防及び/又は治療用医薬組成物 - Google Patents
変形性関節症及び/又は関節リウマチの予防及び/又は治療用医薬組成物Info
- Publication number
- JP7840505B2 JP7840505B2 JP2025568955A JP2025568955A JP7840505B2 JP 7840505 B2 JP7840505 B2 JP 7840505B2 JP 2025568955 A JP2025568955 A JP 2025568955A JP 2025568955 A JP2025568955 A JP 2025568955A JP 7840505 B2 JP7840505 B2 JP 7840505B2
- Authority
- JP
- Japan
- Prior art keywords
- galnac
- osteoarthritis
- expression
- rheumatoid arthritis
- chondrocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biotechnology (AREA)
- Physical Education & Sports Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024015445 | 2024-02-05 | ||
| JP2024015445 | 2024-02-05 | ||
| PCT/JP2025/003340 WO2025169865A1 (ja) | 2024-02-05 | 2025-02-03 | 変形性関節症及び/又は関節リウマチの予防及び/又は治療用医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2025169865A1 JPWO2025169865A1 (https=) | 2025-08-14 |
| JPWO2025169865A5 JPWO2025169865A5 (https=) | 2026-01-28 |
| JP7840505B2 true JP7840505B2 (ja) | 2026-04-03 |
Family
ID=96699915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025568955A Active JP7840505B2 (ja) | 2024-02-05 | 2025-02-03 | 変形性関節症及び/又は関節リウマチの予防及び/又は治療用医薬組成物 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP7840505B2 (https=) |
| WO (1) | WO2025169865A1 (https=) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008078588A1 (ja) | 2006-12-25 | 2008-07-03 | National University Corporation Tokyo Medical And Dental University | 関節軟骨の変性を治療又は予防するための医薬及び方法 |
| JP2012512177A (ja) | 2008-12-16 | 2012-05-31 | カオフシウン メディカル ユニヴァーシティー | 早期変形性関節症の治療 |
| JP2021084867A (ja) | 2019-11-27 | 2021-06-03 | 学校法人慶應義塾 | 変形性関節症の予防薬及び治療薬 |
-
2025
- 2025-02-03 WO PCT/JP2025/003340 patent/WO2025169865A1/ja active Pending
- 2025-02-03 JP JP2025568955A patent/JP7840505B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008078588A1 (ja) | 2006-12-25 | 2008-07-03 | National University Corporation Tokyo Medical And Dental University | 関節軟骨の変性を治療又は予防するための医薬及び方法 |
| JP2012512177A (ja) | 2008-12-16 | 2012-05-31 | カオフシウン メディカル ユニヴァーシティー | 早期変形性関節症の治療 |
| JP2021084867A (ja) | 2019-11-27 | 2021-06-03 | 学校法人慶應義塾 | 変形性関節症の予防薬及び治療薬 |
Non-Patent Citations (2)
| Title |
|---|
| HAYASHI, S. et al.,A genome-wide association study identifying the SNPs predictive of rapid joint destruction in patients with rheumatoid arthritis,Biomedical Reports,2021年,Vol. 14, No. 3,31,doi:10.3892/br.2021.1407, ISSN:2049-9434 |
| 積山 賢 ほか,N-アセチルガラクトサミン転移酵素12(GalNAc-T12)の軟骨細胞への影響の検討,第66回 日本リウマチ学会総会・学術集会 プログラム・抄録集,2022年03月07日,p. 341 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025169865A1 (ja) | 2025-08-14 |
| JPWO2025169865A1 (https=) | 2025-08-14 |
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