JP7839260B2 - 糖尿病性腎症の処置のためのil1ra由来ペプチド - Google Patents
糖尿病性腎症の処置のためのil1ra由来ペプチドInfo
- Publication number
- JP7839260B2 JP7839260B2 JP2024501194A JP2024501194A JP7839260B2 JP 7839260 B2 JP7839260 B2 JP 7839260B2 JP 2024501194 A JP2024501194 A JP 2024501194A JP 2024501194 A JP2024501194 A JP 2024501194A JP 7839260 B2 JP7839260 B2 JP 7839260B2
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- compound
- seq
- peptide
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2021/069450 WO2023284947A1 (en) | 2021-07-13 | 2021-07-13 | Il1ra derived peptides for treatment of diabetic nephropathy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024525669A JP2024525669A (ja) | 2024-07-12 |
| JP2024525669A5 JP2024525669A5 (https=) | 2024-07-23 |
| JP7839260B2 true JP7839260B2 (ja) | 2026-04-01 |
Family
ID=76958978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024501194A Active JP7839260B2 (ja) | 2021-07-13 | 2021-07-13 | 糖尿病性腎症の処置のためのil1ra由来ペプチド |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240216464A1 (https=) |
| EP (1) | EP4351617B1 (https=) |
| JP (1) | JP7839260B2 (https=) |
| CN (1) | CN117642174A (https=) |
| AU (1) | AU2021455992A1 (https=) |
| CA (1) | CA3226176A1 (https=) |
| ES (1) | ES3026437T3 (https=) |
| WO (1) | WO2023284947A1 (https=) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014510082A (ja) | 2011-03-14 | 2014-04-24 | セロドウス アーエスアー | インターロイキン−1受容体のアンタゴニスト |
| WO2017063657A1 (en) | 2015-10-14 | 2017-04-20 | Phlogo Aps | Il1ra-derived peptide antagonist |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075222A (en) | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
| KR101317045B1 (ko) * | 2002-09-06 | 2013-10-16 | 암젠 인코포레이티드 | 치료학적 인체 항-il-1r1 모노클로날 항체 |
| WO2018022982A1 (en) * | 2016-07-29 | 2018-02-01 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
-
2021
- 2021-07-13 JP JP2024501194A patent/JP7839260B2/ja active Active
- 2021-07-13 WO PCT/EP2021/069450 patent/WO2023284947A1/en not_active Ceased
- 2021-07-13 AU AU2021455992A patent/AU2021455992A1/en active Pending
- 2021-07-13 CA CA3226176A patent/CA3226176A1/en active Pending
- 2021-07-13 ES ES21742823T patent/ES3026437T3/es active Active
- 2021-07-13 EP EP21742823.4A patent/EP4351617B1/en active Active
- 2021-07-13 US US18/577,588 patent/US20240216464A1/en active Pending
- 2021-07-13 CN CN202180100484.5A patent/CN117642174A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014510082A (ja) | 2011-03-14 | 2014-04-24 | セロドウス アーエスアー | インターロイキン−1受容体のアンタゴニスト |
| WO2017063657A1 (en) | 2015-10-14 | 2017-04-20 | Phlogo Aps | Il1ra-derived peptide antagonist |
Non-Patent Citations (2)
| Title |
|---|
| Kidney Int,2014年06月30日,vol. 87(1),pp. 74-84 |
| SER140 is a peptide with anti-inflammatory properties, [online],Serodus,2021年04月19日,<URL: https://web.archive.org/web/20210419192221/https://serodus.com/ser140/ >, [retrieved on 2025.07.24] which retrieved from the internet |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021455992A1 (en) | 2024-01-18 |
| CA3226176A1 (en) | 2023-01-19 |
| EP4351617B1 (en) | 2025-03-26 |
| WO2023284947A1 (en) | 2023-01-19 |
| EP4351617C0 (en) | 2025-03-26 |
| JP2024525669A (ja) | 2024-07-12 |
| EP4351617A1 (en) | 2024-04-17 |
| ES3026437T3 (en) | 2025-06-11 |
| US20240216464A1 (en) | 2024-07-04 |
| CN117642174A (zh) | 2024-03-01 |
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