JP7807018B2 - 卵子評価方法、卵子評価装置、及び卵子評価用プログラム - Google Patents

卵子評価方法、卵子評価装置、及び卵子評価用プログラム

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Publication number
JP7807018B2
JP7807018B2 JP2023555104A JP2023555104A JP7807018B2 JP 7807018 B2 JP7807018 B2 JP 7807018B2 JP 2023555104 A JP2023555104 A JP 2023555104A JP 2023555104 A JP2023555104 A JP 2023555104A JP 7807018 B2 JP7807018 B2 JP 7807018B2
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egg
evaluation
quality
ovum
target
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Japanese (ja)
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JPWO2023063099A5 (https=
JPWO2023063099A1 (https=
Inventor
求 田中
暁久 山本
佳織 杉村
文敏 古賀
茂樹 北上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOGA FUMITOSHI WOMEN'S CLINIC
Shimadzu Corp
Kyoto University NUC
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KOGA FUMITOSHI WOMEN'S CLINIC
Shimadzu Corp
Kyoto University NUC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G06T7/0016—Biomedical image inspection using an image reference approach involving temporal comparison
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/435—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for embryo or ova transplantation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/20—Analysis of motion
    • G06T7/246—Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G01N2015/1495—Deformation of particles
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20081—Training; Learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30044—Fetus; Embryo

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Quality & Reliability (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Sustainable Development (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
JP2023555104A 2021-10-14 2022-09-29 卵子評価方法、卵子評価装置、及び卵子評価用プログラム Active JP7807018B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021168634 2021-10-14
JP2021168634 2021-10-14
PCT/JP2022/036466 WO2023063099A1 (ja) 2021-10-14 2022-09-29 卵子評価方法、卵子評価装置、及び卵子評価用プログラム

Publications (3)

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JPWO2023063099A1 JPWO2023063099A1 (https=) 2023-04-20
JPWO2023063099A5 JPWO2023063099A5 (https=) 2024-07-24
JP7807018B2 true JP7807018B2 (ja) 2026-01-27

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US (1) US20240319163A1 (https=)
EP (1) EP4417700A4 (https=)
JP (1) JP7807018B2 (https=)
CN (1) CN118176304A (https=)
WO (1) WO2023063099A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12354267B1 (en) * 2024-06-24 2025-07-08 Inti Taiwan, Inc. Oocyte quality analysis system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012531584A (ja) 2009-06-25 2012-12-10 フェイズ ホログラフィック イメージング ペーホーイー アーベー デジタルホログラフィック撮像による卵又は胚の分析
WO2021014461A1 (en) 2019-07-19 2021-01-28 Payeli Sravan Kumar Intracytoplasmic sperm injection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016054684A (ja) 2014-09-09 2016-04-21 国立大学法人名古屋大学 マイクロ流体チップ及びマイクロ流体チップ内のマイクロプローブの駆動方法、弾性粒子の駆動方法、および装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012531584A (ja) 2009-06-25 2012-12-10 フェイズ ホログラフィック イメージング ペーホーイー アーベー デジタルホログラフィック撮像による卵又は胚の分析
WO2021014461A1 (en) 2019-07-19 2021-01-28 Payeli Sravan Kumar Intracytoplasmic sperm injection

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BARNETT-ITZHAKI, Zohar，Machine learning vs. classic statistics for the prediction of IVF outcomes，Journal of Assisted Reproduction and Genetics，2020年08月11日，Vol. 37，No. 10，p.2405-2412，doi.org/10.1007/s10815-020-01908-1
JEONG, ye Gyeong，Injection funnel persistence time and oolemma resistance during intracytoplasmic sperm injection and subsequent embryo development，Journal of Obstetrics and Gynaecology Research，2021年07月20日，Vol. 47，No. 10，p.3590-3597，doi:10.1111/jog.14943
KHALILIAN, Morteza，Estimating zona pellucida hardness under microinjection to assess oocyte/embryo quality: Analytical and experimental studies，Advances in Bioscience and Biotechnology，2013年，Vol. 04，No. 05，p.679-688，doi.org/10.4236/abb.2013.45089
PRIEL, Elad，Zona pellucida shear modulus, a possible novel non-invasive method to assist in embryo selection during in-vitro fertilization treatment，Scientific Reports，2020年08月21日，Vol. 10，No. 1，DOI: 10.1038/s41598-020-70739-y
TARGOSZ, Anna，Semantic segmentation of human oocyte images using deep neural networks，BioMedical Engineering OnLine，2021年04月23日，Vol. 20，No. 1，doi.org/10.1186/s12938-021-00864-w
村山 嘉延，選択的単一胚移植（eSET）へ向けた体外受精卵の品質モニタリングシステムの開発，科学研究費助成事業（科学研究費補助金）研究成果報告書，2012年03月31日，機関番号：35665, 課題番号：20680026

Also Published As

Publication number Publication date
WO2023063099A1 (ja) 2023-04-20
JPWO2023063099A1 (https=) 2023-04-20
EP4417700A1 (en) 2024-08-21
CN118176304A (zh) 2024-06-11
US20240319163A1 (en) 2024-09-26
EP4417700A4 (en) 2025-04-23

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