JP7805010B2 - コロナウイルス感染を予防および処置する化合物および方法 - Google Patents

コロナウイルス感染を予防および処置する化合物および方法

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Publication number
JP7805010B2
JP7805010B2 JP2022566726A JP2022566726A JP7805010B2 JP 7805010 B2 JP7805010 B2 JP 7805010B2 JP 2022566726 A JP2022566726 A JP 2022566726A JP 2022566726 A JP2022566726 A JP 2022566726A JP 7805010 B2 JP7805010 B2 JP 7805010B2
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JP
Japan
Prior art keywords
sars
cov
coronavirus
compound
3clpro
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JP2022566726A
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English (en)
Japanese (ja)
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JP2023524274A5 (cg-RX-API-DMAC10.html
JP2023524274A (ja
Inventor
ロ，ジャー－メン
ホアン，チェン
ビー ウー，イェー
ジュー リアン，ホイ
リン，ペイ－シン
チャン，ハオ
チュウ，ウェイ－チョン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arjil Biotech Holding Co Ltd
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Arjil Biotech Holding Co Ltd
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Publication of JP2023524274A5 publication Critical patent/JP2023524274A5/ja
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022566726A 2020-05-01 2021-04-29 コロナウイルス感染を予防および処置する化合物および方法 Active JP7805010B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063018690P 2020-05-01 2020-05-01
US63/018,690 2020-05-01
PCT/US2021/029840 WO2021222534A1 (en) 2020-05-01 2021-04-29 Compounds and methods for prevention and treatment of coronavirus infections

Publications (3)

Publication Number Publication Date
JP2023524274A JP2023524274A (ja) 2023-06-09
JP2023524274A5 JP2023524274A5 (cg-RX-API-DMAC10.html) 2024-06-14
JP7805010B2 true JP7805010B2 (ja) 2026-01-23

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JP2022566726A Active JP7805010B2 (ja) 2020-05-01 2021-04-29 コロナウイルス感染を予防および処置する化合物および方法

Country Status (7)

Country Link
US (1) US12433901B2 (cg-RX-API-DMAC10.html)
EP (1) EP4142713A1 (cg-RX-API-DMAC10.html)
JP (1) JP7805010B2 (cg-RX-API-DMAC10.html)
CN (1) CN116568295B (cg-RX-API-DMAC10.html)
AU (1) AU2021264554B2 (cg-RX-API-DMAC10.html)
TW (1) TW202206080A (cg-RX-API-DMAC10.html)
WO (1) WO2021222534A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021311814A1 (en) * 2020-07-23 2023-03-02 Arjil Biotech Holding Company Limited Method and composition for inhibiting virus infection
WO2023065223A1 (zh) * 2021-10-21 2023-04-27 北京大学深圳研究生院 鱼针草酸在制备抑制新型冠状病毒与变异株的感染与复制的医药组合物中的用途

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US20140105928A1 (en) * 2004-01-06 2014-04-17 Paul Edward Stamets Antiviral and antibacterial activity from medicinal mushrooms
CA2481489A1 (en) * 2002-11-29 2004-06-17 Morinaga Milk Industry Co., Ltd. Cysteine protease inhibitor
TWI389699B (zh) * 2009-02-13 2013-03-21 高雄醫學大學 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法
US7919665B2 (en) 2009-02-17 2011-04-05 Conocophillips Company Mercury removal from hydrocarbons
TW201231474A (en) * 2011-01-26 2012-08-01 Univ Kaohsiung Medical Triterpenoid composition of Antrodia cinnamomea, preparation and analysis method thereof
FI126047B (en) * 2012-08-28 2016-06-15 John Eriksson Pharmaceutical compositions of anisomelic acid and their use
TWI453026B (zh) * 2013-05-14 2014-09-21 Jenisa Biotechnology Corp Ltd 魚針草萃取物及其純化物抗流感病毒之用途
US9645651B2 (en) 2013-09-24 2017-05-09 Microsoft Technology Licensing, Llc Presentation of a control interface on a touch-enabled device based on a motion or absence thereof
CN113795258B (zh) * 2019-02-25 2024-04-16 吉亚生技控股股份有限公司 抑制病毒感染的方法及组合物
US11779620B2 (en) * 2020-04-03 2023-10-10 Turtle Bear Holdings, Llc Combined fungal composition for modulating inflammatory response
CN113521060B (zh) * 2020-04-17 2022-12-06 北京大学深圳研究生院 鱼针草内酯抗新型冠状病毒的用途
WO2021218974A1 (en) * 2020-04-28 2021-11-04 Alps Biotech Co., Ltd. Uses of antrodia cinnamomea extract in manufacturing products for reducing expression and treating associated diseases of angiotensin converting enzyme 2

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Acta Pharmacologica Sinica，2011年，Vol.32，pp.904-911
Appl. Sci.，2019年，Vol.9, 4281，pp.1-15，doi:10.3390/app9204281
Journal of Endocrinological Investigation，2020年04月25日，Vol.43，pp.1141-1147，https://doi.org/10.1007/s40618-020-01266-w

Also Published As

Publication number Publication date
TW202206080A (zh) 2022-02-16
AU2021264554B2 (en) 2026-05-21
US20210338690A1 (en) 2021-11-04
CN116568295A (zh) 2023-08-08
AU2021264554A1 (en) 2023-01-05
US12433901B2 (en) 2025-10-07
CN116568295B (zh) 2026-02-13
WO2021222534A1 (en) 2021-11-04
EP4142713A1 (en) 2023-03-08
JP2023524274A (ja) 2023-06-09

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