JP7783187B2 - ステロイドのヒドロキシ化方法 - Google Patents

ステロイドのヒドロキシ化方法

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Publication number
JP7783187B2
JP7783187B2 JP2022552739A JP2022552739A JP7783187B2 JP 7783187 B2 JP7783187 B2 JP 7783187B2 JP 2022552739 A JP2022552739 A JP 2022552739A JP 2022552739 A JP2022552739 A JP 2022552739A JP 7783187 B2 JP7783187 B2 JP 7783187B2
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Prior art keywords
seq
cytochrome
acid
present
group
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JP2022552739A
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Japanese (ja)
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JP2023520307A (ja
JP2023520307A5 (https=
Inventor
シュタウニッヒ、ニコール
オリビエ ドンスバッハ、カイ
Original Assignee
ファーマツェル・ゲーエムベーハー
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022552739A 2020-03-06 2021-03-05 ステロイドのヒドロキシ化方法 Active JP7783187B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20161536.6A EP3875596A1 (de) 2020-03-06 2020-03-06 Verfahren zur hydroxylierung von steroiden
EP20161536.6 2020-03-06
PCT/EP2021/055617 WO2021176068A1 (de) 2020-03-06 2021-03-05 Verfahren zur hydroxylierung von steroiden

Publications (3)

Publication Number Publication Date
JP2023520307A JP2023520307A (ja) 2023-05-17
JP2023520307A5 JP2023520307A5 (https=) 2023-06-16
JP7783187B2 true JP7783187B2 (ja) 2025-12-09

Family

ID=69780052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022552739A Active JP7783187B2 (ja) 2020-03-06 2021-03-05 ステロイドのヒドロキシ化方法

Country Status (5)

Country Link
US (1) US12305212B2 (https=)
EP (2) EP3875596A1 (https=)
JP (1) JP7783187B2 (https=)
KR (1) KR20220150947A (https=)
WO (1) WO2021176068A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3875597A1 (de) * 2020-03-06 2021-09-08 Annikki GmbH Verfahren zur hydroxylierung von steroiden

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005512532A (ja) 2001-08-03 2005-05-12 ディヴァーサ コーポレイション Ｐ４５０酵素、それらをコードした核酸及びそれらの作製と使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
永田 清，"チトクロムＰ－４５０を介した薬物代謝"，日本薬理学雑誌，2009年，第134巻, 第3号，p.146－148

Also Published As

Publication number Publication date
WO2021176068A1 (de) 2021-09-10
US20240240221A1 (en) 2024-07-18
KR20220150947A (ko) 2022-11-11
JP2023520307A (ja) 2023-05-17
EP3875596A1 (de) 2021-09-08
US12305212B2 (en) 2025-05-20
EP4114929A1 (de) 2023-01-11

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