JP7744344B2 - 神経系疾患および障害を改善するための方法 - Google Patents

神経系疾患および障害を改善するための方法

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Publication number
JP7744344B2
JP7744344B2 JP2022537311A JP2022537311A JP7744344B2 JP 7744344 B2 JP7744344 B2 JP 7744344B2 JP 2022537311 A JP2022537311 A JP 2022537311A JP 2022537311 A JP2022537311 A JP 2022537311A JP 7744344 B2 JP7744344 B2 JP 7744344B2
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JP2023507408A5 (enExample
JP2023507408A (ja
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アンソニー ピー. フォード
ガブリエル ヴァルガス
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キュラセン セラピューティクス インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022537311A 2019-12-18 2020-12-17 神経系疾患および障害を改善するための方法 Active JP7744344B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962950077P 2019-12-18 2019-12-18
US62/950,077 2019-12-18
US202063034364P 2020-06-03 2020-06-03
US63/034,364 2020-06-03
PCT/US2020/065655 WO2021127210A1 (en) 2019-12-18 2020-12-17 Methods for improving neurological diseases and disorders

Publications (3)

Publication Number Publication Date
JP2023507408A JP2023507408A (ja) 2023-02-22
JP2023507408A5 JP2023507408A5 (enExample) 2023-12-08
JP7744344B2 true JP7744344B2 (ja) 2025-09-25

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JP2022537311A Active JP7744344B2 (ja) 2019-12-18 2020-12-17 神経系疾患および障害を改善するための方法

Country Status (6)

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US (3) US11607395B2 (enExample)
EP (1) EP4076422A4 (enExample)
JP (1) JP7744344B2 (enExample)
AU (1) AU2020405091B2 (enExample)
CA (1) CA3161376A1 (enExample)
WO (1) WO2021127210A1 (enExample)

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JP2023541379A (ja) * 2020-09-01 2023-10-02 キュラセン セラピューティクス インコーポレイテッド 神経系の疾患及び障害を改善するための組成物及び方法
US12616667B2 (en) * 2021-11-15 2026-05-05 Curasen Therapeutics, Inc. Compositions and methods for improving neurological diseases and disorders
CN115212194B (zh) * 2022-01-07 2024-08-13 中南大学湘雅三医院 纳多洛尔在制备治疗缺血/再灌注损伤药物及细胞保护药物中的应用
CN116212002A (zh) * 2022-01-14 2023-06-06 中南大学湘雅三医院 一种预防或治疗缺血/再灌注损伤的药物组合物及应用
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
WO2023225021A1 (en) * 2022-05-17 2023-11-23 Curasen Therapeutics, Inc. Compositions and methods for treating patients with amyotrophic lateral sclerosis (als)
US20260207533A1 (en) * 2022-12-21 2026-07-23 Curasen Therapeutics, Inc. Methods for treating various conditions and indications with agonists and antagonists
CN120583945A (zh) 2023-01-20 2025-09-02 阿托基公司 用于治疗或预防肌肉消耗的β2-肾上腺素能受体激动剂
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses
WO2025188807A1 (en) * 2024-03-06 2025-09-12 Curasen Therapeutics, Inc. Combination compositions and methods of use
WO2025238248A1 (en) 2024-05-17 2025-11-20 Atrogi Ab USE OF β2-ADRENERGIC RECEPTOR AGONISTS IN TREATING MUSCLE WASTING

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Also Published As

Publication number Publication date
EP4076422A4 (en) 2024-01-24
AU2020405091A1 (en) 2022-07-14
US11607395B2 (en) 2023-03-21
CA3161376A1 (en) 2021-06-24
US20260151356A1 (en) 2026-06-04
US20230181492A1 (en) 2023-06-15
US20210186897A1 (en) 2021-06-24
EP4076422A1 (en) 2022-10-26
WO2021127210A1 (en) 2021-06-24
AU2020405091B2 (en) 2026-04-23
US12558325B2 (en) 2026-02-24
JP2023507408A (ja) 2023-02-22

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