JP7744344B2 - 神経系疾患および障害を改善するための方法 - Google Patents
神経系疾患および障害を改善するための方法Info
- Publication number
- JP7744344B2 JP7744344B2 JP2022537311A JP2022537311A JP7744344B2 JP 7744344 B2 JP7744344 B2 JP 7744344B2 JP 2022537311 A JP2022537311 A JP 2022537311A JP 2022537311 A JP2022537311 A JP 2022537311A JP 7744344 B2 JP7744344 B2 JP 7744344B2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962950077P | 2019-12-18 | 2019-12-18 | |
| US62/950,077 | 2019-12-18 | ||
| US202063034364P | 2020-06-03 | 2020-06-03 | |
| US63/034,364 | 2020-06-03 | ||
| PCT/US2020/065655 WO2021127210A1 (en) | 2019-12-18 | 2020-12-17 | Methods for improving neurological diseases and disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023507408A JP2023507408A (ja) | 2023-02-22 |
| JP2023507408A5 JP2023507408A5 (enExample) | 2023-12-08 |
| JP7744344B2 true JP7744344B2 (ja) | 2025-09-25 |
Family
ID=76437605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022537311A Active JP7744344B2 (ja) | 2019-12-18 | 2020-12-17 | 神経系疾患および障害を改善するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11607395B2 (enExample) |
| EP (1) | EP4076422A4 (enExample) |
| JP (1) | JP7744344B2 (enExample) |
| AU (1) | AU2020405091B2 (enExample) |
| CA (1) | CA3161376A1 (enExample) |
| WO (1) | WO2021127210A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11607395B2 (en) * | 2019-12-18 | 2023-03-21 | Curasen Therapeutics, Inc. | Methods for improving neurological diseases and disorders |
| JP2023541379A (ja) * | 2020-09-01 | 2023-10-02 | キュラセン セラピューティクス インコーポレイテッド | 神経系の疾患及び障害を改善するための組成物及び方法 |
| US12616667B2 (en) * | 2021-11-15 | 2026-05-05 | Curasen Therapeutics, Inc. | Compositions and methods for improving neurological diseases and disorders |
| CN115212194B (zh) * | 2022-01-07 | 2024-08-13 | 中南大学湘雅三医院 | 纳多洛尔在制备治疗缺血/再灌注损伤药物及细胞保护药物中的应用 |
| CN116212002A (zh) * | 2022-01-14 | 2023-06-06 | 中南大学湘雅三医院 | 一种预防或治疗缺血/再灌注损伤的药物组合物及应用 |
| GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
| WO2023225021A1 (en) * | 2022-05-17 | 2023-11-23 | Curasen Therapeutics, Inc. | Compositions and methods for treating patients with amyotrophic lateral sclerosis (als) |
| US20260207533A1 (en) * | 2022-12-21 | 2026-07-23 | Curasen Therapeutics, Inc. | Methods for treating various conditions and indications with agonists and antagonists |
| CN120583945A (zh) | 2023-01-20 | 2025-09-02 | 阿托基公司 | 用于治疗或预防肌肉消耗的β2-肾上腺素能受体激动剂 |
| GB202302225D0 (en) | 2023-02-16 | 2023-04-05 | Atrogi Ab | New medical uses |
| GB202303229D0 (en) | 2023-03-06 | 2023-04-19 | Atrogi Ab | New medical uses |
| GB202403169D0 (en) | 2024-03-05 | 2024-04-17 | Atrogi Ab | New medical uses |
| WO2025188807A1 (en) * | 2024-03-06 | 2025-09-12 | Curasen Therapeutics, Inc. | Combination compositions and methods of use |
| WO2025238248A1 (en) | 2024-05-17 | 2025-11-20 | Atrogi Ab | USE OF β2-ADRENERGIC RECEPTOR AGONISTS IN TREATING MUSCLE WASTING |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140235726A1 (en) | 2013-02-13 | 2014-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improving cognition and increasing dendritic complexity in humans with down syndrome and compositions therefor |
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| US5541188A (en) * | 1987-09-15 | 1996-07-30 | The Rowett Research Institute | Therapeutic applications of beta-adrenergic agonists |
| PL200923B1 (pl) | 1999-08-21 | 2009-02-27 | Nycomed Gmbh | Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu |
| US7135497B1 (en) | 2000-07-07 | 2006-11-14 | New York Medical College | Treating neural conditions resulting from spinal cord contusions and other causes |
| AU2003251949A1 (en) | 2002-07-18 | 2004-02-09 | Vanderbilt University | Therapeutic and screening methods employing partial agonism of the alpha-2a adrenergic receptor subtype |
| CA2544611A1 (en) | 2003-10-09 | 2005-04-21 | Inverseon, Inc. | Method of treating airway diseases with beta-adrenergic inverse agonists |
| US9492114B2 (en) | 2004-06-18 | 2016-11-15 | Banner Health Systems, Inc. | Accelerated evaluation of treatments to prevent clinical onset of alzheimer's disease |
| US7528175B2 (en) | 2004-10-08 | 2009-05-05 | Inverseon, Inc. | Method of treating airway diseases with beta-adrenergic inverse agonists |
| EP1754474A1 (en) | 2005-02-02 | 2007-02-21 | Eucro European Contract Research GmbH & Co. KG | Use of S-Clenbuterol |
| US20080033027A1 (en) | 2005-03-21 | 2008-02-07 | Vicus Therapeutics Spe 1, Llc | Drug combination pharmaceutical compositions and methods for using them |
| WO2006108424A2 (en) | 2005-04-13 | 2006-10-19 | Astion Pharma A/S | Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin |
| US20070021421A1 (en) | 2005-07-25 | 2007-01-25 | Hampton Thomas G | Measurement of gait dynamics and use of beta-blockers to detect, prognose, prevent and treat amyotrophic lateral sclerosis |
| SI1924264T1 (sl) * | 2005-09-01 | 2013-12-31 | F. Hoffmann-La Roche Ag | Diaminopirimidini kot modulatorji p2x3 in p2x2/3 |
| US20110046090A1 (en) | 2005-10-31 | 2011-02-24 | Braincells Inc. | Modulation of neurogenesis with gaba agents and gaba analogs |
| CN1991364A (zh) * | 2005-12-26 | 2007-07-04 | 中国科学院上海生命科学研究院 | 预防和治疗阿尔兹海默症的g蛋白偶联受体拮抗剂 |
| CA2732513C (en) | 2008-08-01 | 2017-04-25 | Arca Biopharma, Inc. | Methods and compositions involving (s)-bucindolol |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2011133226A2 (en) * | 2010-04-22 | 2011-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Method for enhancing learning and memory impaired by neurodegenerative disorders and compounds and compositions for effecting the same |
| EP2696849A4 (en) | 2011-04-13 | 2014-10-29 | Revalesio Corp | COMPOSITIONS AND METHODS FOR INHIBITING AND / OR MODULATING EFFECTOR CELLS IN INFLAMMABLE NEURODEGENERATIVE ILLNESSES |
| US9784001B1 (en) | 2011-05-03 | 2017-10-10 | Paul Kristen, Inc | Adjustable scaffolding suspension assembly |
| WO2013061161A2 (en) * | 2011-10-28 | 2013-05-02 | Green Bcn Consulting Services Sl | New combination therapies for treating neurological disorders |
| US20140256822A1 (en) | 2013-03-11 | 2014-09-11 | Pharmaceutical Productions Inc. | Transmucosal drug delivery system |
| US10111879B2 (en) | 2013-06-27 | 2018-10-30 | Cedars-Sinai Medical Center | Adrenoceptors antagonists for the prevention and treatment of neurodegenerative conditions |
| AU2014287418A1 (en) | 2013-07-08 | 2016-01-28 | Auspex Pharmaceuticals, Inc. | Dihydroxyphenyl neurotransmitter compounds, compositions and methods |
| WO2015126915A2 (en) | 2014-02-18 | 2015-08-27 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improving cognition and social behavior in humans having deficits therein due to neurological disorders and compounds and compositions therefor |
| ES2864079T3 (es) * | 2014-05-30 | 2021-10-13 | Pfizer | Derivados de carbonitrilo como moduladores selectivos del receptor de andrógenos |
| US9889087B2 (en) | 2014-06-10 | 2018-02-13 | The Board Of Trustees Of The Leland Stanford Junior University | Intranasal delivery of β2-adrenergic receptor agonists for improving cognition in humans with down syndrome and compositions therefor |
| US10195198B2 (en) * | 2014-07-03 | 2019-02-05 | Afferent Pharmaceuticals, Inc. | Methods and compositions for treating diseases and conditions |
| TWI728953B (zh) * | 2015-04-24 | 2021-06-01 | 美商安美基公司 | 治療或預防偏頭痛之方法 |
| EP3398614B1 (en) | 2015-12-29 | 2021-07-28 | Kyoto University | Agent for preventing and/or treating alzheimer's disease |
| BR112018073227A2 (pt) | 2016-05-13 | 2019-02-19 | The Board Of Trustees Of The Leland Stanford Junior University | compostos moduladores do receptor adrenérgico e métodos de uso do mesmo |
| WO2018195473A1 (en) | 2017-04-20 | 2018-10-25 | The Brigham And Women's Hospital, Inc. | Combinations including beta-adrenoreceptor agonists for treatment of parkinson's disease and movement disorders |
| EP3806957A4 (en) * | 2018-06-14 | 2022-03-16 | Curasen Therapeutics, Inc. | METHODS OF DIAGNOSIS, MONITORING AND TREATMENT OF NEUROLOGICAL DISEASES AND DISORDERS |
| US10947196B2 (en) * | 2019-03-27 | 2021-03-16 | Curasen Therapeutics, Inc. | Beta adrenergic agonist and methods of using the same |
| US20220401415A1 (en) | 2019-10-25 | 2022-12-22 | Curasen Therapeutics, Inc. | Methods for treating neurological disorders with alpha1a-ar partial agonists |
| US11607395B2 (en) * | 2019-12-18 | 2023-03-21 | Curasen Therapeutics, Inc. | Methods for improving neurological diseases and disorders |
| JP7734700B2 (ja) | 2020-06-04 | 2025-09-05 | キュラセン セラピューティクス インコーポレイテッド | ベータアドレナリンアゴニストの形態及び組成物 |
| WO2023225021A1 (en) * | 2022-05-17 | 2023-11-23 | Curasen Therapeutics, Inc. | Compositions and methods for treating patients with amyotrophic lateral sclerosis (als) |
-
2020
- 2020-12-17 US US17/125,741 patent/US11607395B2/en active Active
- 2020-12-17 CA CA3161376A patent/CA3161376A1/en active Pending
- 2020-12-17 WO PCT/US2020/065655 patent/WO2021127210A1/en not_active Ceased
- 2020-12-17 AU AU2020405091A patent/AU2020405091B2/en active Active
- 2020-12-17 EP EP20902094.0A patent/EP4076422A4/en active Pending
- 2020-12-17 JP JP2022537311A patent/JP7744344B2/ja active Active
-
2023
- 2023-02-09 US US18/107,886 patent/US12558325B2/en active Active
-
2026
- 2026-01-21 US US19/455,349 patent/US20260151356A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140235726A1 (en) | 2013-02-13 | 2014-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improving cognition and increasing dendritic complexity in humans with down syndrome and compositions therefor |
Non-Patent Citations (1)
| Title |
|---|
| Movement Disorders,2002年,Vol.17, No.1, pp.54-59 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4076422A4 (en) | 2024-01-24 |
| AU2020405091A1 (en) | 2022-07-14 |
| US11607395B2 (en) | 2023-03-21 |
| CA3161376A1 (en) | 2021-06-24 |
| US20260151356A1 (en) | 2026-06-04 |
| US20230181492A1 (en) | 2023-06-15 |
| US20210186897A1 (en) | 2021-06-24 |
| EP4076422A1 (en) | 2022-10-26 |
| WO2021127210A1 (en) | 2021-06-24 |
| AU2020405091B2 (en) | 2026-04-23 |
| US12558325B2 (en) | 2026-02-24 |
| JP2023507408A (ja) | 2023-02-22 |
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